AutismKB 2.0

Annotation Detail for ITGB1BP3


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Basic Information Top
Gene Symbol:ITGB1BP3 ( MGC126624,MIBP,NRK2 )
Gene Full Name: integrin beta 1 binding protein 3
Band: 19p13.3
Quick LinksEntrez ID:27231; OMIM: 608705; Uniprot ID:NRK2_HUMAN; ENSEMBL ID: ENSG00000077009; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
NAD-BIOSYNTHESIS-IINAD salvage pathway II
PWY3O-4106NAD salvage pathway III
No data
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009160 cyclonite cyclonite results in decreased expression of ITGB1BP3 mRNAdecreases expression 19417177
D004041 Dietary Fats Dietary Fats results in increased expression of ITGB1BP3 mRNAincreases expression 18042831
C041786 palm oil palm oil results in increased expression of ITGB1BP3 mRNAincreases expression 18042831
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D001161 Arteriosclerosis Dietary Fats 4.5415238619
MESH:D001943 Breast Neoplasms Dietary Fats 2.2420435547
MESH:D050171 Dyslipidemias Dietary Fats 3.7618367378
MESH:D005234 Fatty Liver Dietary Fats 3.7217967931 18296743 19551842 19004024
MESH:D005355 Fibrosis Dietary Fats 4.1718296743
MESH:D006937 Hypercholesterolemia Dietary Fats 4.0821332399
MESH:D006949 Hyperlipidemias Dietary Fats 4.1421332399
MESH:D007249 Inflammation Dietary Fats 2.6220412841
MESH:D007333 Insulin Resistance Dietary Fats 3.3718457598 11836018
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0918296743
MESH:D009765 Obesity Dietary Fats 2.3620132043 21332399 19632207 17217161 16723640 11836018 18457598 20518802 18674790
MESH:D012640 Seizures cyclonite 4.8119417177
MESH:D015430 Weight Gain Dietary Fats 4.1516723640
No data
Pharmacogenomics Knowledge Base Top
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018