AutismKB 2.0

Annotation Detail for CNTN6


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Basic Information Top
Gene Symbol:CNTN6 ( MGC133256,NB3 )
Gene Full Name: contactin 6
Band: 3p26.3
Quick LinksEntrez ID:27255; OMIM: 607220; Uniprot ID:CNTN6_HUMAN; ENSEMBL ID: ENSG00000134115; HGNC ID: 2176
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Axon guidance
Pathway IDPathway Name
200013Notch signaling pathway
No data
Pathway IDPathway Name
500101CHL1 interactions
Related Diseases/Disorders Top
No data
No data
No data
Desease Name
Response to statin therapy
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CNTN6 mRNAaffects expression 16483693
D005419 Flavonoids Flavonoids results in increased expression of CNTN6 mRNAincreases expression 18035473
D013755 Tetradecanoylphorbol Acetate [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CNTN6 mRNAaffects cotreatment|affects expression 16979875
D015032 Zinc [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CNTN6 mRNAaffects cotreatment|affects expression 16979875
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1918287403
MESH:D000169 Acrodermatitis Zinc 6.0316889938 17190629 17202136
MESH:D000544 Alzheimer Disease Zinc 2.8216580781 16325427 17119284 16410023
MESH:D000755 Anemia, Sickle Cell Zinc 5.4116916123
MESH:D001249 Asthma Zinc 3.0417085522
MESH:D001930 Brain Injuries Zinc 5.2517109824
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 5.4318922899
MESH:D002294 Carcinoma, Squamous Cell Zinc 5.4316543248
MESH:D002318 Cardiovascular Diseases Zinc 3.9216936243
MESH:D019465 Craniofacial Abnormalities Zinc 2.4419302082
MESH:D003920 Diabetes Mellitus Zinc 4.5716479319
MESH:D004487 Edema Tetradecanoylphorbol Acetate 4.037812673 11698051 8113982 15177302 8273558 9599246 16716910
MESH:D004938 Esophageal Neoplasms Zinc 2.9316543248
MESH:D005756 Gastritis Zinc 5.5217241300
MESH:D006130 Growth Disorders Zinc 4.1917217573
MESH:D006333 Heart Failure Zinc 3.8317162251
MESH:D006335 Heart Injuries Zinc 6.4917074742
MESH:D016481 Helicobacter Infections Zinc 5.0017241300
MESH:D006527 Hepatolenticular Degeneration Zinc 5.2517276780
MESH:D007249 Inflammation Flavonoids 6.0517296493
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 6.057812673 7562506 8273558 11698051 15177302
MESH:D007511 Ischemia Zinc 5.1916584753
MESH:D007674 Kidney Diseases Zinc 3.5216960431
MESH:D007676 Kidney Failure, Chronic Zinc 4.8516518626
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 2.4811807781
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 7.318985016
MESH:D008325 Mammary Neoplasms, Experimental Zinc 7.3112773700
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 3.2415976015
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 4.8518922899 8330346 12065085 18404319
MESH:D011225 Pre-Eclampsia Zinc 4.4817114810
MESH:D011471 Prostatic Neoplasms Zinc 3.7616517595 12429649 16700911 16606632
MESH:D012162 Retinal Degeneration Zinc 4.4216584753
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 3.438330346 11807781 18404319 12065085 8985016
MESH:D014062 Tongue Neoplasms Zinc 4.7916543248
Pathway ID Pathway Name
REACT:18266 Axon guidance
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA26690
  • No data
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018