AutismKB 2.0

Annotation Detail for RBMS3


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Basic Information Top
Gene Symbol:RBMS3 ( FLJ36544 )
Gene Full Name: RNA binding motif, single stranded interacting protein 3
Band: 3p24.1
Quick LinksEntrez ID:27303; OMIM: 605786; Uniprot ID:RBMS3_HUMAN; ENSEMBL ID: ENSG00000144642; HGNC ID: 13427
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
CHEMDEPENDENCY
Bone Mineral Density
smoking cessation
METABOLIC
Desease Name
Bone mineral density
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of RBMS3 mRNAdecreases expression 20713471
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RBMS3 mRNAdecreases expression 19150397
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of RBMS3 mRNAaffects expression 17484886
D016572 Cyclosporine Cyclosporine results in decreased expression of RBMS3 mRNAdecreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of RBMS3 mRNAaffects expression 17555576
D008748 Methylcholanthrene Methylcholanthrene results in decreased expression of RBMS3 mRNAdecreases expression 20713471
D013629 Tamoxifen Tamoxifen affects the expression of RBMS3 mRNAaffects expression 17555576
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.9914745880
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.3817505938
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.3720127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.3714692618
MESH:D000236 Adenoma Benzo(a)pyrene 7.366695378
MESH:D000236 Adenoma Methylcholanthrene 7.3610545420 6695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.4319183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.8211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8215885639
MESH:D050197 Atherosclerosis Methylcholanthrene 3.6011922910
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9520146248 17474063
MESH:D001943 Breast Neoplasms Methylcholanthrene 1.9517474063
MESH:D001943 Breast Neoplasms Tamoxifen 1.9519103187 18815881 20390343 19155303 20544844 19142967 18997820 11161223 19200415 19011961 19487384 18629630 21152245 18855134 19189210 16273361 15565566 19189212 17261762 16202921 16818667 17893378 18821012 19084267 20065188 19221464 17440819 18351453 20005174 19244106 18984771 19059307 18425577 20135344 17049068 19066611 19289846 19115204 20859285 19410462 21138602 19288272 17242785 15668708 16873071
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.1415721981 3786805 15673190 16011737 16227642 16097048 18705752 10355542 15700767 16124888 16050911 16192424
MESH:D002277 Carcinoma Methylcholanthrene 4.1910545420
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.8719066611
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 3.1118788625
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 3.1116924424
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1120419170
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.8817572228
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 12.3220889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 12.3212371664
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 12.3216192471
MESH:D002779 Cholestasis Cyclosporine 8.4619486331
MESH:D002779 Cholestasis Ethinyl Estradiol 8.4616105132 11677210 16919318 17333356 15861022 17681005 17110522
MESH:D003711 Demyelinating Diseases Tamoxifen 4.7219031437
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.7219279558
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 2.107120509 21278145 19085960 6884620 3732212 9327722 7440962 7179309 15027814 10915739 19336974 2869522 15998439 4309450 11566570 16227642 10092053 17522070 3786805 6623471 15968718 16177239
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 10.0612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 10.0619031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.2120544844 17893378 19155303 16202921
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.5420426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.5416530937
MESH:D005234 Fatty Liver Carbon Tetrachloride 21.2312795759 19224547 12631006 16239168 16045604 15959796 61145 17595544
MESH:D005234 Fatty Liver Cyclosporine 21.2319224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 21.2315345470
MESH:D005234 Fatty Liver Tamoxifen 21.2319224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.3916709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.9214745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.5819069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 5.3410962813 14633661
MESH:D005355 Fibrosis Carbon Tetrachloride 9.8918705752
MESH:D005355 Fibrosis Cyclosporine 9.8912639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.628708960
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.7820471113
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.8215720958
MESH:D006505 Hepatitis Carbon Tetrachloride 3.9219110552 19900420
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.9316899240
MESH:D006973 Hypertension Cyclosporine 2.1810903974
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.4515338365
MESH:D007021 Hypospadias Ethinyl Estradiol 4.1716569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.7712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.6617937319
MESH:D007249 Inflammation Tamoxifen 2.4819457130
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.8815604871
MESH:D007674 Kidney Diseases Cyclosporine 2.488314463 18776723 10903974
MESH:D007680 Kidney Neoplasms Cyclosporine 8.0912371664
MESH:D007680 Kidney Neoplasms Tamoxifen 8.0918625569
MESH:D008064 Lipidoses Tamoxifen 3.3515342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.9417174718 11903743 17334410 11408273 21278145 16943688 16221502 17157831 16239168
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 2.5415893842 18429990 15959796 18418968 16192424 12649538 15057751 12389079 15123356 18279442 12632512 13678700 17565644 15818738 18166357 17557913 15650968 14620537 12609069 17761835 17900296 12632514 17944888 18006644 16015684 15338365 18263696 17922224 15362042 18156304 17631135 17525996 18472332 15730626 12741479 12667390 20821823 15925388 12586293 15876570 18420326 16638106 18277467 14512876 14748882 18205269 16011737 17708605 18705752 12445418 12958196 15370692 11481614 12666154 15052691 17823541 18317297 17766677 14716833 12898905 14724832 12546737 18395095 17640975 18481824 16027843 16116963 17721639 15996030 18251166 18339082 18376398 16097048 18395914 17976157 15673190 18187930 12445421 16033810 18054572 17869086 18472094 17714472 17805973 18210741 16136751 14716496 15931870 16248980 17481882 10355542 17698563 18412020
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 2.5418564211
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1316246199 15720792 15830285 17285989 16964402
MESH:D017093 Liver Failure Carbon Tetrachloride 4.5215123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.9516899240 14706259
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 7.9620195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 7.9619294768
MESH:D008113 Liver Neoplasms Tamoxifen 7.9616684651
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 6.7315583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 6.731399818 598648
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 3.6420064080 20464547 18816296 17053015 18569708 18520028 6695378 20869020 20135361
MESH:D008175 Lung Neoplasms Methylcholanthrene 3.6415390079 17909032 16271038 11893704 20970405 20512841 16337739 6695378 1399818 9230183 10545420 7750092 21163286
MESH:D008175 Lung Neoplasms Tamoxifen 3.6418625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.1519428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.7914580682 19196723 11731420 16827153 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.9919453300
MESH:D008545 Melanoma Tamoxifen 1.9119393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.5815990972
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.2316801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4016381670
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.6419393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5919410462
MESH:D009369 Neoplasms Benzo(a)pyrene 2.2811141357
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.4419196722 19200415 19189210
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.8817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5319348381 18481113
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.9911578682
MESH:D011230 Precancerous Conditions Cyclosporine 3.4712371664
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.0717292933
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.0715067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.7116919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.3016882103
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.4819755658 10029692
MESH:D013088 Spermatocele Ethinyl Estradiol 13.0916709447
MESH:D013088 Spermatocele Tamoxifen 13.0916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.4319457130
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5620155912 2093021
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.9211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.4015669648
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.3017053015
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 5.308653321 17572228 16712894
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.6314692618
MESH:D014605 Uveitis Cyclosporine 4.431336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.8215869587 14671159
MESH:D014985 Xerophthalmia Cyclosporine 4.8817120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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