Annotation Detail for RRP7A
Basic Information
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| Gene Symbol: | RRP7A ( BK126B4.3,CGI-96,MGC150422,MGC150423 ) |
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| Gene Full Name: | ribosomal RNA processing 7 homolog A (S. cerevisiae) |
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| Band: | 22q13.2 |
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| Quick Links | Entrez ID:27341; OMIM: NA; Uniprot ID:RRP7A_HUMAN; ENSEMBL ID: ENSG00000189306; HGNC ID: 24286 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of RRP7A mRNA | affects expression | 17562736
|
| C014347 |
decitabine |
decitabine results in increased expression of RRP7A mRNA | increases expression | 17908484
|
| D015741 |
Metribolone |
Metribolone results in increased expression of RRP7A mRNA | increases expression | 17010196
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of RRP7A mRNA | affects binding|decreases expression|increases activity | 19710929
|
| D012643 |
Selenium |
Selenium results in increased expression of RRP7A mRNA | increases expression | 19244175
|
| C004648 |
testosterone enanthate |
testosterone enanthate affects the expression of RRP7A mRNA | affects expression | 17440010
|
| D014810 |
Vitamin E |
Vitamin E results in increased expression of RRP7A mRNA | increases expression | 19244175
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.42 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
3.88 | 16434500 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.29 | 10982225 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.43 | 19483382 |
| MESH:D001943 |
Breast Neoplasms |
|
decitabine |
2.55 | 18320071 19208741 |
| MESH:D002252 |
Carbon Tetrachloride Poisoning |
|
Vitamin E |
4.29 | 16050911 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
1.40 | 3084413 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
decitabine |
2.65 | 19215824 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.73 | 10977129 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.03 | 19176532 |
| MESH:D003092 |
Colitis |
|
Selenium |
4.14 | 17936198 |
| MESH:D003110 |
Colonic Neoplasms |
|
decitabine |
2.37 | 17616700 |
| MESH:D015179 |
Colorectal Neoplasms |
|
decitabine |
2.10 | 18981723 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Vitamin E |
1.92 | 19769572 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.53 | 18249437 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
4.01 | 18713872 10915739 12153990 19739265 11834606 16781746 19923254 12705907 19420014 11743745 10774834 11529661 11421492 11461765 16177239 11739529 14986274 19416960 17522070 11287661 10663392 16109766 16227642 18071297 14550746 17906064 12958197 14725611 2444490 16081117 19085960 16485898 12594235 17562736 19164858 19370779 16393943 15968718 12540782 15619225 12392966 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Selenium |
4.01 | 15131321 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.54 | 19426721 |
| MESH:C538011 |
Eales disease |
|
Vitamin E |
5.15 | 9068938 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.76 | 12083418 |
| MESH:D004701 |
Endocrine Gland Neoplasms |
|
decitabine |
5.56 | 19294695 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.04 | 20131406 19236843 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.12 | 16983495 |
| MESH:D006258 |
Head and Neck Neoplasms |
|
decitabine |
3.66 | 19215824 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Vitamin E |
3.12 | 16080930 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
7.48 | 20558911 |
| MESH:D006333 |
Heart Failure |
|
Selenium |
7.48 | 17162251 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.35 | 18467677 19772884 19176532 16221962 |
| MESH:D006548 |
Hernia, Diaphragmatic |
|
Vitamin E |
2.78 | 16863852 16490937 |
| MESH:D019247 |
HIV Wasting Syndrome |
|
testosterone enanthate |
6.19 | 17440010 |
| MESH:D019584 |
Hot Flashes |
|
Vitamin E |
4.41 | 14716179 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.92 | 16870215 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.45 | 20558911 |
| MESH:D007248 |
Infertility, Male |
|
decitabine |
3.38 | 17581917 |
| MESH:D007251 |
Influenza, Human |
|
Selenium |
12.48 | 16624496 |
| MESH:D007251 |
Influenza, Human |
|
Vitamin E |
12.48 | 16624496 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.80 | 16306350 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
6.45 | 15629191 12587719 |
| MESH:D007674 |
Kidney Diseases |
|
Vitamin E |
6.45 | 12488133 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Selenium |
4.17 | 16518626 |
| MESH:D007938 |
Leukemia |
|
decitabine |
3.19 | 18980019 19235587 |
| MESH:D007951 |
Leukemia, Myeloid |
|
decitabine |
4.28 | 18454857 19117987 17236224 |
| MESH:D015470 |
Leukemia, Myeloid, Acute |
|
decitabine |
2.41 | 18460780 19010910 18704418 19387464 17679729 18206229 |
| MESH:D015477 |
Leukemia, Myelomonocytic, Chronic |
|
decitabine |
5.91 | 18055864 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
2.45 | 15474484 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Vitamin E |
2.45 | 16169303 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.68 | 19014921 16610002 19460945 16611625 19784758 12587719 12969438 11587558 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.50 | 17185352 16871587 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.90 | 16377806 20007298 15890375 |
| MESH:D008171 |
Lung Diseases |
|
Vitamin E |
3.35 | 16863852 |
| MESH:D008175 |
Lung Neoplasms |
|
Vitamin E |
1.90 | 11062179 |
| MESH:D008223 |
Lymphoma |
|
decitabine |
3.61 | 19470736 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Selenium |
2.92 | 15318939 |
| MESH:D008545 |
Melanoma |
|
decitabine |
2.27 | 17785578 16505122 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
3.93 | 19513568 |
| MESH:D008654 |
Mesothelioma |
|
Selenium |
2.88 | 15107826 |
| MESH:D009101 |
Multiple Myeloma |
|
decitabine |
3.54 | 18172295 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
3.86 | 16239165 |
| MESH:D009190 |
Myelodysplastic Syndromes |
|
decitabine |
3.52 | 19010910 19157545 16882708 18608210 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.24 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.16 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
decitabine |
5.42 | 17925555 19470736 19116145 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
5.42 | 17405874 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.10 | 18514411 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.86 | 20558911 |
| MESH:D010051 |
Ovarian Neoplasms |
|
decitabine |
2.72 | 19259094 19331143 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.62 | 16870215 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
decitabine |
2.84 | 19294695 |
| MESH:D010954 |
Plasmacytoma |
|
Selenium |
5.33 | 15087411 |
| MESH:D055728 |
Primary Myelofibrosis |
|
decitabine |
5.09 | 17616702 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Vitamin E |
3.26 | 15084515 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.50 | 19058328 |
| MESH:D012208 |
Rhabdomyosarcoma |
|
decitabine |
4.71 | 19155313 |
| MESH:D012871 |
Skin Diseases |
|
Vitamin E |
2.50 | 18709164 |
| MESH:D013274 |
Stomach Neoplasms |
|
decitabine |
2.10 | 19037991 |
| MESH:D020521 |
Stroke |
|
Vitamin E |
3.74 | 16517955 |
| MESH:D013964 |
Thyroid Neoplasms |
|
decitabine |
3.54 | 17967635 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
decitabine |
2.81 | 19087683 17616700 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.28 | 10982225 |
| MESH:D014604 |
Uveal Neoplasms |
|
decitabine |
5.36 | 17785578 |
| Pathway ID |
Pathway Name |
|---|
| KEGG:03008 |
Ribosome biogenesis in eukaryotes |
Related Pathway Information