AutismKB 2.0

Annotation Detail for CECR6


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Basic Information Top
Gene Symbol:CECR6 ( - )
Gene Full Name: cat eye syndrome chromosome region, candidate 6
Band: -
Quick LinksEntrez ID:27439; OMIM: NA; Uniprot ID:CECR6_HUMAN; ENSEMBL ID: ENSG00000183307; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D004958 Estradiol ESR1 protein affects the reaction [Estradiol promotes the reaction [NCOA1 protein binds to CECR6 gene]]affects binding|affects reaction|increases reaction 17962382
D004958 Estradiol ESR1 protein affects the reaction [Estradiol promotes the reaction [NCOA2 protein binds to CECR6 gene]]affects binding|affects reaction|increases reaction 17962382
D004958 Estradiol ESR1 protein affects the reaction [Estradiol promotes the reaction [NCOA3 protein binds to CECR6 gene]]affects binding|affects reaction|increases reaction 17962382
D004958 Estradiol ESR2 protein affects the reaction [Estradiol promotes the reaction [NCOA2 protein binds to CECR6 gene]]affects binding|affects reaction|increases reaction 17962382
D004958 Estradiol Estradiol promotes the reaction [ESR1 protein binds to CECR6 gene]affects binding|increases reaction 17962382
D004958 Estradiol Estradiol promotes the reaction [ESR2 protein binds to CECR6 gene]affects binding|increases reaction 17962382
D004958 Estradiol Estradiol results in increased expression of CECR6 mRNAincreases expression 17962382
D013629 Tamoxifen Tamoxifen results in increased expression of CECR6 mRNAincreases expression 17962382
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 5.6214745880
MESH:D000230 Adenocarcinoma Estradiol 2.1811473722
MESH:D001943 Breast Neoplasms Estradiol 2.0817018787 17289903 16675129 19861407 14630087 12948864 18497071 17261762
MESH:D001943 Breast Neoplasms Tamoxifen 2.0818821012 19011961 18997820 19221464 19244106 18855134 16273361 17893378 17242785 18815881 19059307 18351453 19066611 18629630 20065188 19142967 20135344 19189210 16818667 19189212 19155303 16202921 11161223 19084267 20859285 19487384 15668708 19200415 18425577 19289846 19115204 20390343 20544844 17049068 19410462 21152245 17440819 17261762 21138602 19288272 16873071 18984771 20005174 15565566 19103187
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 5.3516111702
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 5.2719066611
MESH:D006528 Carcinoma, Hepatocellular Estradiol 3.1516924424
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 3.1516924424
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 4.1217572228
MESH:D002471 Cell Transformation, Neoplastic Estradiol 3.0918566989
MESH:D003711 Demyelinating Diseases Tamoxifen 5.1319031437
MESH:D003928 Diabetic Nephropathies Estradiol 10.4419279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 10.4419279558
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 4.2119031437
MESH:D016889 Endometrial Neoplasms Estradiol 8.3911473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 8.3919155303 20544844 17893378 16202921
MESH:D005234 Fatty Liver Tamoxifen 3.7119224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.5016709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 5.4114745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 5.0719069698
MESH:D006558 Herpes Genitalis Estradiol 6.1015709030
MESH:D019584 Hot Flashes Estradiol 4.8217088409
MESH:D007249 Inflammation Tamoxifen 2.5719457130
MESH:D007333 Insulin Resistance Estradiol 3.2616627594 16393666
MESH:D007674 Kidney Diseases Estradiol 2.8315618244
MESH:D007680 Kidney Neoplasms Estradiol 8.8615610895
MESH:D007680 Kidney Neoplasms Tamoxifen 8.8618625569
MESH:D008064 Lipidoses Tamoxifen 3.5017567588 15342952
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 2.5514659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 2.5518564211
MESH:D008113 Liver Neoplasms Tamoxifen 2.3516684651
MESH:D008175 Lung Neoplasms Tamoxifen 1.7518625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.6419428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 6.9517203775 11807958 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 6.9519196722 11731420 16827153 14580682 19196723
MESH:D020149 Manganese Poisoning Estradiol 16.6619453300
MESH:D020149 Manganese Poisoning Tamoxifen 16.6619453300
MESH:D008545 Melanoma Tamoxifen 1.9319393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 5.0715990972
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.6616810080
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.7019393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.6319410462
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 5.0719200415 19196722 19189210
MESH:D009389 Neovascularization, Pathologic Estradiol 4.6217289903
MESH:D009421 Nervous System Malformations Estradiol 4.3216427766 11399458
MESH:D010051 Ovarian Neoplasms Estradiol 2.3319401270
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.4420887781
MESH:D011471 Prostatic Neoplasms Estradiol 3.0816740699
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.0815067354
MESH:D013088 Spermatocele Tamoxifen 5.3616709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.9219457130
MESH:D013978 Tibial Fractures Estradiol 5.7619048282
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 2.508653321 17572228 16712894
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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