AutismKB 2.0

Annotation Detail for GLS


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Basic Information Top
Gene Symbol:GLS ( AAD20,DKFZp686O15119,FLJ10358,GLS1,KIAA0838 )
Gene Full Name: glutaminase
Band: 2q32.2
Quick LinksEntrez ID:2744; OMIM: 138280; Uniprot ID:GLSK_HUMAN; ENSEMBL ID: ENSG00000115419; HGNC ID: 4331
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
CITRULBIO-PWYcitrulline biosynthesis
PWY-5004superpathway of citrulline metabolism
Pathway IDPathway Name
hsa00250Alanine, aspartate and glutamate metabolism
hsa00910Nitrogen metabolism
hsa00330Arginine and proline metabolism
hsa04964Proximal tubule bicarbonate reclamation
hsa01100Metabolic pathways
hsa00471D-Glutamine and D-glutamate metabolism
Pathway IDPathway Name
Synaptic Transmission
Metabolism of amino acids and derivatives
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1770Melanoma
2126Encephalopathies
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in decreased expression of GLS mRNAdecreases expression 20406850
D000082 Acetaminophen Acetaminophen affects the expression of GLS mRNAaffects expression 17562736
D020106 Acrylamide Acrylamide results in increased expression of GLS mRNAincreases expression 15749267
D000641 Ammonia GLS protein affects the secretion of Ammoniaaffects secretion 20719974
D000641 Ammonia [Hydrochloric Acid results in decreased expression of GLS protein] which results in increased secretion of Ammoniadecreases expression|increases secretion 20719974
D000641 Ammonia [RHBG protein mutant form results in decreased expression of GLS protein] which results in increased secretion of Ammoniadecreases expression|increases secretion 20719974
D000643 Ammonium Chloride Ammonium Chloride results in increased expression of GLS proteinincreases expression 18287403
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GLS mRNAaffects expression 16483693
D001151 Arsenic Arsenic results in decreased activity of GLS proteindecreases activity 19428935
C006632 arsenic trioxide arsenic trioxide results in increased expression of GLS mRNAincreases expression 20458559
D001205 Ascorbic Acid [Quercetin co-treated with Ascorbic Acid] results in decreased expression of GLS mRNAaffects cotreatment|decreases expression 17639512
C020979 benzenearsonic acid benzenearsonic acid results in decreased activity of GLS proteindecreases activity 19428935
C020979 benzenearsonic acid benzenearsonic acid results in decreased expression of GLS proteindecreases expression 19428935
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of GLS mRNAincreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of GLS mRNAdecreases expression 20018196
C006780 bisphenol A bisphenol A affects the expression of GLS mRNAaffects expression 20170705
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GLS mRNAaffects cotreatment|decreases expression 20360939
D003520 Cyclophosphamide GLS protein affects the susceptibility to Cyclophosphamideaffects response to substance 16217747
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GLS mRNAaffects cotreatment|decreases expression 20360939
D002117 Calcitriol Calcitriol results in decreased expression of GLS mRNAdecreases expression 16002434
C493087 diphenylarsinic acid diphenylarsinic acid results in decreased activity of GLS proteindecreases activity 19428935
C493087 diphenylarsinic acid diphenylarsinic acid results in decreased expression of GLS proteindecreases expression 19428935
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of GLS mRNAaffects expression 20170705
D005419 Flavonoids Flavonoids results in increased expression of GLS mRNAincreases expression 18035473
D006851 Hydrochloric Acid [Hydrochloric Acid results in decreased expression of GLS protein] which results in increased secretion of Ammoniadecreases expression|increases secretion 20719974
D006851 Hydrochloric Acid Hydrochloric Acid results in increased expression of GLS proteinincreases expression 20719974
D007213 Indomethacin Indomethacin results in decreased expression of GLS mRNAdecreases expression 16984733
D008094 Lithium Lithium inhibits the reaction [Methamphetamine results in decreased expression of GLS mRNA]decreases expression|decreases reaction 19149911
D008694 Methamphetamine Lithium inhibits the reaction [Methamphetamine results in decreased expression of GLS mRNA]decreases expression|decreases reaction 19149911
D008694 Methamphetamine Methamphetamine results in decreased expression of GLS mRNAdecreases expression 19149911
D008694 Methamphetamine Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of GLS mRNA]decreases expression|decreases reaction 19149911
D011794 Quercetin [Quercetin co-treated with Ascorbic Acid] results in decreased expression of GLS mRNAaffects cotreatment|decreases expression 17639512
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of GLS mRNAincreases expression 20106945
D014635 Valproic Acid Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of GLS mRNA]decreases expression|decreases reaction 19149911
C025643 vinclozolin vinclozolin affects the expression of GLS mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.5515322242 14514962 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 7.558875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.7219490988
MESH:D000138 Acidosis Ammonium Chloride 9.9618287403
MESH:D000138 Acidosis Hydrochloric Acid 9.9616144966 20872349 15920416 19262391 12771618 11574821
MESH:D000141 Acidosis, Renal Tubular Hydrochloric Acid 5.5517183249
MESH:D000142 Acidosis, Respiratory Hydrochloric Acid 5.5820597076
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7117505938
MESH:D055371 Acute Lung Injury Hydrochloric Acid 4.5719094174 19060228 19760209 16759491 11953099 11850527 15970105
MESH:D000230 Adenocarcinoma arsenic trioxide 9.6911798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 9.6920127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.6914692618
MESH:D000230 Adenocarcinoma Indomethacin 9.6916537180
MESH:D000236 Adenoma Benzo(a)pyrene 10.466695378
MESH:D000236 Adenoma Diethylnitrosamine 10.466695378 10737359
MESH:D000236 Adenoma Indomethacin 10.4611497255
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 9.2919052882 18056438 19061943 17162532 17620307 16434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.2916835633
MESH:D018246 Adrenocortical Adenoma Arsenic 4.9817306315
MESH:D016301 Alveolar Bone Loss Indomethacin 5.1417225004
MESH:D000544 Alzheimer Disease Indomethacin 4.6317627676 15579461
MESH:D000544 Alzheimer Disease Lithium 4.6319621015
MESH:D000550 Amblyopia Valproic Acid 5.0017688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7511748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.0317084956
MESH:D000799 Angioedema Acetaminophen 3.6110982225
MESH:D000860 Anoxia Hydrochloric Acid 5.0815090967
MESH:D001008 Anxiety Disorders Valproic Acid 8.2617497229
MESH:D001008 Anxiety Disorders vinclozolin 8.2619015723
MESH:D001014 Aortic Aneurysm Indomethacin 4.6310231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 10.9619183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 10.9610388637
MESH:D020261 Arsenic Poisoning Arsenic 2.8012569548 18414634 16835338 16251483
MESH:D001161 Arteriosclerosis Cyclophosphamide 9.4215014928
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.4211256880
MESH:D018771 Arthralgia Indomethacin 4.942160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5315885639
MESH:D001172 Arthritis, Rheumatoid Indomethacin 2.7711248219
MESH:D001260 Ataxia Telangiectasia Quercetin 4.7515336622
MESH:D050197 Atherosclerosis Arsenic 3.1212928151 19371607
MESH:D001321 Autistic Disorder Acetaminophen 1.8518445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8518775368 18940202 16609825 15238991 19460635 18558336 19232924 18396377 18177632 18985861 17688650 18316065 17157402 20603192 17507914
MESH:D001327 Autoimmune Diseases Quercetin 4.1819761891
MESH:D001477 Bartter Syndrome Indomethacin 4.7610684365
MESH:D001714 Bipolar Disorder Lithium 7.2420338123 20046352 17594078 19153942
MESH:D001714 Bipolar Disorder Valproic Acid 7.2417594078 20046352
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 14.3116206674
MESH:D001778 Blood Coagulation Disorders Hydrochloric Acid 14.3115920416
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 14.3112125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.5415746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.548888407
MESH:D001862 Bone Resorption bisphenol A 3.6611985600
MESH:D001929 Brain Edema Ammonia 12.2511481608 20217200 19393034
MESH:D001929 Brain Edema Indomethacin 12.2511481608
MESH:D002545 Brain Ischemia Indomethacin 4.1912524144
MESH:D001943 Breast Neoplasms Acrylamide 6.7718183576 16253758
MESH:D001943 Breast Neoplasms Ascorbic Acid 6.7716443354
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 6.7720146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 6.7717123778
MESH:D001943 Breast Neoplasms Calcitriol 6.7711237771
MESH:D001943 Breast Neoplasms Cyclophosphamide 6.7715093573 11325840 17020986 18234424 15136595 16978400 12006526 17388661 18323546
MESH:D001943 Breast Neoplasms Diethylnitrosamine 6.7717474063
MESH:D001943 Breast Neoplasms Indomethacin 6.7717401462
MESH:D001943 Breast Neoplasms Quercetin 6.7718628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 6.7720435547
MESH:D016535 Bronchial Hyperreactivity Hydrochloric Acid 4.4112378975
MESH:D001986 Bronchial Spasm Hydrochloric Acid 5.2415578804
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1211589617
MESH:D002056 Burns Indomethacin 4.4810459503
MESH:D002100 Cachexia Indomethacin 4.7811239499 16537180 15141370 15625704
MESH:D002105 Cadmium Poisoning Quercetin 5.3116962696
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6216835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.4615504454 17687452
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 16.2616705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 16.263084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 16.2617306315 16507464
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 16.2615073043 16217749 11135700 14691202 15553829
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 16.2619701751
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 16.2611831363 18971187 3084413 18978308 16779866 19383236 19701751 20524982 21159647 16681979 19539802 20512989 19052882 17162532 18210153 18665156 16328049 10737359 20514400 19822196 16502159 17428255 16288022 18691550 18393292 16830150 17173139 19519916 19171122 20084675 18788625 18056438 16878318 20101231 17138121 19418558 17761372 16698587 17978847 16540662 19208518 19394651 10672840 20935162 16935385 3581430 20214788 19107877 17055752 18785209 16569478 16807293 20727157 18494052 18506893 19335982 19919837 20432363 20007298
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 16.2616391822
MESH:D006528 Carcinoma, Hepatocellular Quercetin 16.2619519916 12508355
MESH:D002278 Carcinoma in Situ bisphenol A 4.7617123778
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 10.7716152834
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 10.7711053908
MESH:D018276 Carcinoma, Medullary Indomethacin 5.1218791128 14736730 11352223
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.7317234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.6419014326
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 6.5916201981
MESH:D002292 Carcinoma, Renal Cell Indomethacin 6.5917341418
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9212490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 10.2818922899 17687452 15504454
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 10.2820419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 10.2811237771
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 10.2815482327 12636206
MESH:D002295 Carcinoma, Transitional Cell Arsenic 3.8818640142
MESH:D006332 Cardiomegaly Quercetin 6.3919794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.3918670907 16120746 18850075
MESH:D002318 Cardiovascular Diseases Arsenic 3.2915738583 17938729 19152805
MESH:D002340 Carotid Artery Diseases Arsenic 4.1218022660 16973168
MESH:D002386 Cataract Acetaminophen 2.4510977129
MESH:D002418 Cattle Diseases Acrylamide 5.2212510666
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 10.286135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.2820889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 10.2821159647 7505956 17174075 2727394
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.6320734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.6919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.6916835633
MESH:D002764 Cholecystitis Indomethacin 4.9411181007
MESH:D002779 Cholestasis Ethinyl Estradiol 2.7116105132 15861022 16919318 11677210 17681005 17333356 17110522
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.018697196 15668235 15340226 16354765 12621046
MESH:D003110 Colonic Neoplasms Indomethacin 3.8815786552 11260862 15625704 15637740 15963497 15936596
MESH:D003110 Colonic Neoplasms Quercetin 3.8811134977 19056647 17148506 17191121 16640504 15741050 19440933
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.4120501625
MESH:D015179 Colorectal Neoplasms Indomethacin 3.4117054584 12606626 11197048 18059344
MESH:D015179 Colorectal Neoplasms Quercetin 3.4118852136 18095365
MESH:D003139 Common Cold Ascorbic Acid 5.2417323712
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8714669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.9712609071
MESH:D018352 Coronavirus Infections Indomethacin 5.4917302372
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.6210525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.6210048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Valproic Acid 3.6216575769 8888407 17688650
MESH:D003456 Cryptorchidism vinclozolin 4.1214966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.7918551238
MESH:D003556 Cystitis Cyclophosphamide 11.3416651033 18372110 18295254 12388444 17010015 16614059 12161096 10498854 18483878 15643279 18710439 11948286 17979934 18093676 16989017 16413132 10700343 12913760 18433785 15276878
MESH:D003556 Cystitis Hydrochloric Acid 11.3419279288 12599022 20719367 12853844
MESH:D018856 Cystitis, Interstitial Hydrochloric Acid 5.5817714534
MESH:D007644 Darier Disease Lithium 5.6820338123
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.8815213294
MESH:D017449 Dermatitis, Allergic Contact Ammonia 4.5416823706
MESH:D018500 Diabetes Insipidus, Nephrogenic Lithium 5.5219244398
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 8.0515331540 11751995 10990075
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 8.0519496084
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 3.1518772604
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 6.8416506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.8420387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.8417107852
MESH:D003967 Diarrhea Indomethacin 3.587907874 7237001
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 11.2521346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.2515619225 10915739 19370779 11461765 10663392 16227642 16485898 11287661 11743745 12958197 19420014 17522070 11529661 14725611 12392966 15968718 16393943 17906064 11739529 18071297 12153990 16177239 18713872 12705907 12540782 16781746 10774834 19739265 17562736 11421492 14550746 19416960 19164858 19085960 14986274 16081117 2444490 16109766 12594235 11834606 19923254
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 11.2519107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.2520420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 11.251733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.8719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5911462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.9218446180 16326151 18043480 16133044 17190690 12774134
MESH:D004381 Duodenal Ulcer Indomethacin 3.9217151854 11595415 17329845 17351913 17045617 11535926 17202747 16699067 11991626 10671773 11595431
MESH:D004421 Dystonia Valproic Acid 3.841851702
MESH:C538011 Eales disease Ascorbic Acid 5.249068938
MESH:D004487 Edema Indomethacin 6.248985016 7907874 10653021 16100529 7990266 8273558 19703484
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.2411000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.6718230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 8.3615138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.3612538720
MESH:D004715 Endometriosis Indomethacin 8.4115652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.4110568697 9294722
MESH:D019446 Endotoxemia Indomethacin 4.2718509659
MESH:D004751 Enteritis Indomethacin 4.5210567023 16328016 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.7617980183
MESH:D004802 Eosinophilia Cyclophosphamide 8.4911006010
MESH:D004802 Eosinophilia Indomethacin 8.4911298111
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 3.9317275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 3.693922381 16628512
MESH:D004827 Epilepsy Valproic Acid 2.8220417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.406426943 6254150 7562514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.077750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.843659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.8916302075
MESH:D004935 Esophageal Diseases Hydrochloric Acid 5.5619566590
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 9.9020426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 9.9012903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 9.9016530937
MESH:D004938 Esophageal Neoplasms Indomethacin 9.9011005569
MESH:D004941 Esophagitis Hydrochloric Acid 5.7712928072
MESH:D004942 Esophagitis, Peptic Hydrochloric Acid 5.7811346197 14621274 20516732
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8411564622
MESH:D005234 Fatty Liver arsenic trioxide 17.0915073043
MESH:D005234 Fatty Liver Diethylnitrosamine 17.0921071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 17.0915345470
MESH:D005234 Fatty Liver Valproic Acid 17.0914986274 19224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2311858732
MESH:D005315 Fetal Diseases Valproic Acid 4.6616575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.918888407 18558336
MESH:D005334 Fever Indomethacin 3.9211852909 10431976 17627676
MESH:D005354 Fibrosarcoma Indomethacin 4.6610962813
MESH:D005355 Fibrosis Hydrochloric Acid 19.4118497604
MESH:D005355 Fibrosis Indomethacin 19.4117994277
MESH:D005355 Fibrosis Quercetin 19.4119474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 19.4120067830
MESH:D005499 Folliculitis Indomethacin 4.9411298111
MESH:D005534 Foot Diseases Arsenic 5.336392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.0416904648
MESH:D005739 Gas Poisoning Hydrochloric Acid 5.2412378975
MESH:D005756 Gastritis Acetaminophen 10.3816983495
MESH:D005756 Gastritis Indomethacin 10.3815046732
MESH:D005764 Gastroesophageal Reflux Hydrochloric Acid 5.1120616304 19957777 20545468 19951613 20516732 12212954
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.7016973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.0716417039
MESH:D005909 Glioblastoma Indomethacin 6.9812870263
MESH:D005909 Glioblastoma Quercetin 6.9819804834
MESH:D005910 Glioma Indomethacin 6.0218371953 16487511
MESH:D005910 Glioma Quercetin 6.0217643826
MESH:D018316 Gliosarcoma Cyclophosphamide 5.2811389073
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.1011849393
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3610696789
MESH:D006073 Gout Indomethacin 5.1211248219
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.8116376943 11014644 15172196
MESH:D006258 Head and Neck Neoplasms Indomethacin 3.5915482327
MESH:D006356 Heartburn Hydrochloric Acid 5.5619566590
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 15.0916080930
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 15.0920471113
MESH:D006330 Heart Defects, Congenital Lithium 15.0919638421
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 15.0910048152 11294989
MESH:D006467 Hemophilia A Cyclophosphamide 5.0611918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1311000095
MESH:D006501 Hepatic Encephalopathy Ammonia 10.7112420312 16338762 20549931
MESH:D006501 Hepatic Encephalopathy Indomethacin 10.7115633222
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 5.3014986274
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.4615135802
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.6715340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 3.4016490937 16863852
MESH:D006689 Hodgkin Disease Cyclophosphamide 3.6017606976 16135485
MESH:D006849 Hydrocephalus Valproic Acid 4.6417688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8116959395 18606429 16354765 8697196 15340226
MESH:D006930 Hyperalgesia Acetaminophen 7.2416870215
MESH:D006930 Hyperalgesia Indomethacin 7.2412727271
MESH:D034321 Hyperamylasemia Indomethacin 5.4917883296
MESH:D006940 Hyperemia Hydrochloric Acid 11.9712646421
MESH:D006940 Hyperemia Indomethacin 11.9712524144
MESH:D006943 Hyperglycemia Quercetin 3.8311834736 18262572
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.2617050553
MESH:D006948 Hyperkinesis Methamphetamine 5.2817658665
MESH:D006949 Hyperlipidemias Indomethacin 3.9517546600
MESH:D006973 Hypertension Arsenic 8.1716076760 9931084 11953799
MESH:D006973 Hypertension Quercetin 8.1718356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.1718670907 18850075
MESH:D006975 Hypertension, Portal Hydrochloric Acid 5.1216984587
MESH:D006976 Hypertension, Pulmonary Hydrochloric Acid 4.2919262391
MESH:D006987 Hypesthesia Arsenic 5.3316093927
MESH:D007021 Hypospadias Ethinyl Estradiol 3.5816945680 16569931
MESH:D007022 Hypotension Hydrochloric Acid 4.5511574821
MESH:D007077 Ileal Diseases Indomethacin 4.7910574470 18306037
MESH:D007079 Ileitis Indomethacin 5.1216133968 10651667 10647630
MESH:D007154 Immune System Diseases Cyclophosphamide 5.1016076520
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.1416133044
MESH:D007247 Infertility, Female Acrylamide 9.6811020651
MESH:D007247 Infertility, Female Ethinyl Estradiol 9.6812013081
MESH:D007248 Infertility, Male Acrylamide 14.9011020651 12507653 15749267 15355880
MESH:D007248 Infertility, Male Cyclophosphamide 14.9016517039 7193160
MESH:D007248 Infertility, Male Ethinyl Estradiol 14.9017937319
MESH:D007248 Infertility, Male vinclozolin 14.9016467254
MESH:D007249 Inflammation Diethylnitrosamine 14.6318785209
MESH:D007249 Inflammation Flavonoids 14.6317296493
MESH:D007249 Inflammation Hydrochloric Acid 14.6311574821
MESH:D007249 Inflammation Indomethacin 14.6312568917 3291741 7812673
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 14.6312200463 12878042
MESH:D007251 Influenza, Human Quercetin 4.2816624496
MESH:D007333 Insulin Resistance bisphenol A 3.1416393666
MESH:D007410 Intestinal Diseases Hydrochloric Acid 9.5811574821
MESH:D007410 Intestinal Diseases Indomethacin 9.5815831440 11855677 17329856 15610444 17994277 10210152 11713966 18236018 11686837
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.3910783313
MESH:D019586 Intracranial Hypertension Indomethacin 5.1415241188
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1316580747
MESH:D007579 Jejunal Diseases Indomethacin 4.7910574470 16133968 18306037
MESH:D007627 Keloid Quercetin 4.7317086741
MESH:D007642 Keratosis Arsenic 4.7616930632 12749816
MESH:D007674 Kidney Diseases Acetaminophen 13.4512587719 15629191
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 13.4515369732
MESH:D007674 Kidney Diseases Indomethacin 13.4517190690
MESH:D007674 Kidney Diseases Quercetin 13.4516962696
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 2.8016705839
MESH:D007818 Laryngeal Diseases Hydrochloric Acid 6.1316498863
MESH:D007826 Laryngismus Hydrochloric Acid 6.1311510729
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.7212228301 10320625 11703811
MESH:D007938 Leukemia arsenic trioxide 9.9615070760
MESH:D007938 Leukemia Cyclophosphamide 9.9610602166
MESH:D007938 Leukemia Quercetin 9.9617468513
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.4017802794 17658394 17008537 18172266 17296974 18587576
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.5912560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.0816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 13.1914633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 13.1910373061
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 13.1910785260 15631656 16572323
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.5619077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.9316467208 20471514 19850784 17050201 16968895
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 5.9318360721
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 5.9316294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 12.0417339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 12.0419642359 15336539 16891316 11161223 16112521 17869043 17649720 16330433 16823087 12679006 17107899 19225113 17712046 15622746 19035177 16966277 15213294 17217047 9834237 12018890 19075265 15748426 12712474 16331271 11468182
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 12.0416766008
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.1316882451
MESH:D007964 Leukocytosis Indomethacin 5.1416537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.4917980183
MESH:D007970 Leukopenia Cyclophosphamide 4.7411830472 10052129
MESH:D007984 Leydig Cell Tumor vinclozolin 4.5016417039
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.4911479899
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.6619638242 18522880 18407596 18665156 20032147
MESH:D008103 Liver Cirrhosis Hydrochloric Acid 6.6616984587
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 3.4318194892
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 3.4312741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.4312878042
MESH:D008107 Liver Diseases Acetaminophen 6.1719784758 16610002 19460945 12587719 11587558 16611625 19014921 12969438
MESH:D008107 Liver Diseases Arsenic 6.1711134558
MESH:D008107 Liver Diseases Diethylnitrosamine 6.1717034775
MESH:D017114 Liver Failure, Acute Acetaminophen 3.0416871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 20.567678174
MESH:D008113 Liver Neoplasms Arsenic 20.5616368122
MESH:D008113 Liver Neoplasms arsenic trioxide 20.5614682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 20.5621137059 20195826
MESH:D008113 Liver Neoplasms Diethylnitrosamine 20.5618754104 20492335 19073162 2422723 19690152 21047994 19426721 19642983 18644402 16942905 20137499 21167192 21278145 10737359 12771043 19996281 20101389 19256749 20452335 20118626 18648771 15885732 15175105 9163691 19812893 20583210 19254457 19427195 19638242 20405173 19294768 19833225 12112319 20501860 19499222 18978307 18977376 19090486 19551842 20434301 19850985 2862719 21071580 19255062
MESH:D008113 Liver Neoplasms Quercetin 20.5618980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 20.5616984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 21.542876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 21.5420377131
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 21.5418544905
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 21.5418775883 18253720 18079962 2563599 18544905 16842330 19539802 19004024 16267830 19126423 17854601 18282651 9362446 3124819 19519916 18093689 18164116 18308698 19009564 21159647 17174075 17942915
MESH:D008114 Liver Neoplasms, Experimental Quercetin 21.5419519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 21.5412151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.1815213294
MESH:D008171 Lung Diseases Ascorbic Acid 7.6316863852
MESH:D008171 Lung Diseases Hydrochloric Acid 7.6316784557
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.0317228818
MESH:D055370 Lung Injury Hydrochloric Acid 4.5418497604 16129981 19644408 18339021 21114838 18573544 20597076 15044056 11395602 15090967 15607125 19262391 21311175 17627322
MESH:D008175 Lung Neoplasms Arsenic 12.4819168569 17306315 17976673
MESH:D008175 Lung Neoplasms arsenic trioxide 12.4819825857 11798837
MESH:D008175 Lung Neoplasms Ascorbic Acid 12.4816401635
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 12.4820135361 18816296 20869020 20464547 20064080 18569708 6695378 18520028 17053015
MESH:D008175 Lung Neoplasms Diethylnitrosamine 12.4820512841 20970405 21163286 6695378
MESH:D008175 Lung Neoplasms Indomethacin 12.4811497255 11053908 16537180
MESH:D008175 Lung Neoplasms Quercetin 12.4816280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 12.4811884234 19555203
MESH:D008223 Lymphoma Cyclophosphamide 3.6812854902
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 4.3816675587
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 3.9811911406
MESH:D008546 Melanoma, Experimental Acetaminophen 10.0819513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 10.0816388313
MESH:D008881 Migraine Disorders Indomethacin 7.1911903285
MESH:D008881 Migraine Disorders Valproic Acid 7.1918803445 18765137
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.0916381670
MESH:D009062 Mouth Neoplasms Indomethacin 8.0912636206
MESH:D009101 Multiple Myeloma arsenic trioxide 2.9519417148 11468182 15949261 14977855 19549372
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.828888407
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.4418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.9916882451 16105982
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 6.9917596541
MESH:D009203 Myocardial Infarction Hydrochloric Acid 9.3118534312
MESH:D009203 Myocardial Infarction Lithium 9.3116288908
MESH:D009203 Myocardial Infarction Quercetin 9.3119595682
MESH:D017202 Myocardial Ischemia Arsenic 8.4115371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.4112213967
MESH:D015428 Myocardial Reperfusion Injury Quercetin 3.6219207477
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.637678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.7416624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.653581430 9029167
MESH:D009362 Neoplasm Metastasis Indomethacin 5.6516537180 11053908 11239499
MESH:D009369 Neoplasms Benzo(a)pyrene 7.7511141357
MESH:D009369 Neoplasms Cyclophosphamide 7.7518854779
MESH:D009369 Neoplasms Quercetin 7.7515185748
MESH:D009374 Neoplasms, Experimental Indomethacin 3.9110663608 15625704
MESH:D009410 Nerve Degeneration Acrylamide 4.5212387367 11264303 12387366
MESH:D009422 Nervous System Diseases Acrylamide 4.7912507653 12164553
MESH:D009421 Nervous System Malformations bisphenol A 8.8616427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.8614600291
MESH:D009436 Neural Tube Defects Arsenic 11.3516620997
MESH:D009436 Neural Tube Defects arsenic trioxide 11.3510525206
MESH:D009436 Neural Tube Defects Valproic Acid 11.3516359493 8888407
MESH:D009447 Neuroblastoma Cyclophosphamide 3.528761367 15176712 16115947
MESH:D019636 Neurodegenerative Diseases Acetaminophen 13.0018514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 13.0020387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 13.0012349958
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 4.6612837982 8761367
MESH:D020078 Neurogenic Inflammation Arsenic 9.9817056641
MESH:D020078 Neurogenic Inflammation Quercetin 9.9817929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.8920387270
MESH:D009503 Neutropenia Cyclophosphamide 4.118291058
MESH:D009765 Obesity Ascorbic Acid 3.0917217161
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.946374098
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.7216049721
MESH:D009784 Occupational Diseases Hydrochloric Acid 8.7212378975
MESH:D009845 Oligospermia Cyclophosphamide 4.4816517039
MESH:D010003 Osteoarthritis Indomethacin 3.537009135
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.0119495926
MESH:D010049 Ovarian Diseases bisphenol A 4.7611985600
MESH:D010051 Ovarian Neoplasms Arsenic 7.5717306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 7.5712452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Quercetin 7.5719005980
MESH:D010146 Pain Acetaminophen 10.3116870215
MESH:D010146 Pain Cyclophosphamide 10.3118093676 12161096
MESH:D010146 Pain Indomethacin 10.3117627676 13679232 3291741 17440234
MESH:D010149 Pain, Postoperative Indomethacin 4.4518702446 12538197
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 11.7015580305
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 11.7011332152
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 11.7016540662
MESH:D010190 Pancreatic Neoplasms Quercetin 11.7016965848
MESH:D010195 Pancreatitis Indomethacin 3.7115028970 17883296
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4711578682
MESH:D010235 Paraganglioma arsenic trioxide 3.9519927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.4916537180
MESH:D020734 Parkinsonian Disorders Indomethacin 3.9212349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.4911903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0212520081
MESH:D010437 Peptic Ulcer Indomethacin 4.9211148446
MESH:D010518 Periodontitis Indomethacin 4.6817225004
MESH:D010523 Peripheral Nervous System Diseases Acrylamide 9.6311510240
MESH:D010523 Peripheral Nervous System Diseases Arsenic 9.6316093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.7615371236 16905509 6392382
MESH:D011015 Pneumonia, Aspiration Hydrochloric Acid 5.1415970105 15607125 18573544 18497604
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3418163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.592563599
MESH:D011230 Precancerous Conditions Quercetin 8.5919056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 3.6821297632
MESH:D047928 Premature Birth Indomethacin 4.9017000239
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 21.3510548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 21.3511399792 11222880 11118676 11896295
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 21.3520603192
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 21.3518220299 18042343 19015723
MESH:D011469 Prostatic Diseases vinclozolin 4.7018220299
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.5515572423
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.0020887781
MESH:D011471 Prostatic Neoplasms Arsenic 2.0716140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0719131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.0717292933
MESH:D011471 Prostatic Neoplasms bisphenol A 2.0716740699
MESH:D011471 Prostatic Neoplasms Calcitriol 2.0716289102 16644109 18247401 12479363 15754350
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 2.0717136230
MESH:D011471 Prostatic Neoplasms Quercetin 2.0714715546 17292933
MESH:D011472 Prostatitis vinclozolin 4.7018629315
MESH:D011507 Proteinuria Arsenic 8.7821343184
MESH:D011507 Proteinuria Indomethacin 8.7811849393
MESH:D011537 Pruritus Ethinyl Estradiol 3.0916919318 15861022
MESH:D019310 Pseudolymphoma Valproic Acid 4.3111422049 12752131
MESH:D011629 Puberty, Precocious bisphenol A 4.5610548101
MESH:D001261 Pulmonary Atelectasis Hydrochloric Acid 5.7820597076
MESH:D011654 Pulmonary Edema Hydrochloric Acid 4.9815090967
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 5.1014606601
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 3.2016636934
MESH:D012128 Respiratory Distress Syndrome, Adult Hydrochloric Acid 4.5518339021 17627322 18549715 16784557 16129981
MESH:D012133 Respiratory Paralysis Hydrochloric Acid 6.1311510729
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6218990726
MESH:D012140 Respiratory Tract Diseases Hydrochloric Acid 4.9420516732
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 3.2516849425
MESH:D012208 Rhabdomyosarcoma Valproic Acid 3.9619155313
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.7416646077
MESH:D012554 Schistosomiasis japonica Quercetin 5.3116862918
MESH:D012559 Schizophrenia Valproic Acid 2.0415737665 19110320
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 4.6116636934
MESH:D012640 Seizures 2,6-dinitrotoluene 9.1218551238
MESH:D012640 Seizures Lithium 9.1219660546
MESH:D012640 Seizures Valproic Acid 9.1217978042 14763951 11738929 3137016 16876388 11044598 15475178 1511512
MESH:D012871 Skin Diseases Arsenic 5.1216759981 19834688 15952646 6392382 17938729 17453740 16702368 17050553 18709164 16353154 17548696
MESH:D012871 Skin Diseases Ascorbic Acid 5.1218709164
MESH:D012878 Skin Neoplasms Arsenic 8.8217029826 17050553 17976673 16251483 19538983 15504454
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 8.8219755658 10029692
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.8216192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.7116709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 5.2816517039
MESH:D016135 Spinal Dysraphism Valproic Acid 3.6119490988
MESH:D013226 Status Epilepticus Lithium 11.8919430551 19570321 19951488
MESH:D013226 Status Epilepticus Valproic Acid 11.8912833885
MESH:D013272 Stomach Diseases Indomethacin 4.1916280098 15472012 18209964 17160473 10192188 10486359 16113693 15038085 18545984 10215738 17638125 16184426 17207306
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.5417007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 4.5420155912 2093021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 4.5418456281
MESH:D013274 Stomach Neoplasms Indomethacin 4.5415609394
MESH:D013276 Stomach Ulcer Ascorbic Acid 11.1718726076
MESH:D013276 Stomach Ulcer Hydrochloric Acid 11.1717189318 16755016 15309881
MESH:D013276 Stomach Ulcer Indomethacin 11.1717895592 12498302 17977527 18726076 16631530 18237397 15104355 12500499 11906479 11729361 17918041 11595415 16755016 11595431 17135157 10878458 10423059 18193104 1323529 16252198 18543354 11523592 18431645 18299717 17627676 16169175 10750652 18181030 16397915 16934674 14567935 18209962 15138204 18087811 16150113 17654042 12077510 17657623 12467913 11145282 12787963 15255614
MESH:D020521 Stroke Ascorbic Acid 4.1116517955 16403987
MESH:D019966 Substance-Related Disorders bisphenol A 3.7616045194 16684133
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 4.8312837982
MESH:D013733 Testicular Diseases Acrylamide 5.0015864552
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4111994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9615669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6712697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 11.0619014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 11.067505956
MESH:D013964 Thyroid Neoplasms Indomethacin 11.0614736730 18791128 11352223
MESH:D016171 Torsades de Pointes arsenic trioxide 3.7315213294
MESH:D014178 Translocation, Genetic Valproic Acid 5.0017262798
MESH:D014456 Ulcer Indomethacin 4.6610574470 17380554
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.293119515
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 18.7216049721
MESH:D001749 Urinary Bladder Neoplasms Arsenic 18.7219322015 19429237 11144890 15987713 17976673 17306315 18640142
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 18.7211780464 12845720 12973940 20435036
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 18.7217053015
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 18.7214692829
MESH:D001749 Urinary Bladder Neoplasms Quercetin 18.7216720314
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.428888407
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.0910091137
MESH:D014581 Urticaria Acetaminophen 2.7710982225
MESH:D014591 Uterine Diseases bisphenol A 4.7814652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.0814692618
MESH:D014652 Vascular Diseases Arsenic 4.5117056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3315869587 14671159
MESH:D014839 Vomiting Indomethacin 4.5211897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0215886252
Pathway ID Pathway Name
KEGG:00250 Alanine, aspartate and glutamate metabolism
KEGG:00330 Arginine and proline metabolism
KEGG:00471 D-Glutamine and D-glutamate metabolism
KEGG:04724 Glutamatergic synapse
KEGG:01100 Metabolic pathways
REACT:13 Metabolism of amino acids and derivatives
KEGG:00910 Nitrogen metabolism
KEGG:04964 Proximal tubule bicarbonate reclamation
REACT:13685 Synaptic Transmission
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28734
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA450197l-leucine
    PA10090l-glutamine
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00130 - L-Glutamine Dietary supplement;Micronutrient;Non-Essential Amino Acids
    DB00142 - L-Glutamic Acid Dietary supplement;Micronutrient;Non-Essential Amino Acids
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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