AutismKB 2.0

Annotation Detail for GOLGB1


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Basic Information Top
Gene Symbol:GOLGB1 ( GCP,GCP372,GIANTIN,GOLIM1 )
Gene Full Name: golgin B1
Band: 3q13.33
Quick LinksEntrez ID:2804; OMIM: 602500; Uniprot ID:GOGB1_HUMAN; ENSEMBL ID: ENSG00000173230; HGNC ID: 4429
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of GOLGB1 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GOLGB1 mRNAaffects expression 16483693
D003010 Clorgyline Clorgyline results in increased expression of GOLGB1 mRNAincreases expression 19691856
D016572 Cyclosporine Cyclosporine results in increased expression of GOLGB1 mRNAincreases expression 20106945
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of GOLGB1 mRNAaffects cotreatment|increases expression 17183730
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of GOLGB1 mRNAaffects binding|decreases expression|increases activity 19710929
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of GOLGB1 mRNAaffects cotreatment|increases expression 17183730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 3.888875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.2119490988
MESH:D000138 Acidosis Ammonium Chloride 3.9518287403
MESH:D055371 Acute Lung Injury pirinixic acid 3.4218653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.8816434500
MESH:D000550 Amblyopia Valproic Acid 5.6817688650
MESH:D001008 Anxiety Disorders Valproic Acid 3.7917497229
MESH:D001321 Autistic Disorder Valproic Acid 1.9916609825 18316065 18775368 18558336 17157402 20603192 18177632 17507914 19460635 15238991 18940202 18985861 19232924 18396377 17688650
MESH:D001714 Bipolar Disorder Valproic Acid 3.2017594078 20046352
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.4319483382
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.578888407
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 1.7816705839
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 7.196135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.1912371664
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.7920734317
MESH:D002779 Cholestasis Cyclosporine 8.4419486331
MESH:D002779 Cholestasis pirinixic acid 8.4419176532
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.9017688650 8888407 16575769
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.3818551238
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5318249437
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 4.1621346803 18551238
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 4.1619641884 1733752
MESH:D004421 Dystonia Valproic Acid 4.351851702
MESH:D004487 Edema pirinixic acid 2.7612083418
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.513659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 4.363922381 16628512
MESH:D004827 Epilepsy Valproic Acid 3.0620417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.846254150 7562514 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.667750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.463659116
MESH:D005234 Fatty Liver Cyclosporine 14.7719224547
MESH:D005234 Fatty Liver pirinixic acid 14.7719236843 20131406
MESH:D005234 Fatty Liver Valproic Acid 14.7719224547 14986274
MESH:D005315 Fetal Diseases Valproic Acid 5.3316575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.468888407 18558336
MESH:D005355 Fibrosis Cyclosporine 3.5012639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.628708960
MESH:D006333 Heart Failure pirinixic acid 2.6920558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.8215720958
MESH:D006529 Hepatomegaly pirinixic acid 3.3516221962 18467677 19772884 19176532
MESH:D006849 Hydrocephalus Valproic Acid 5.2617688650
MESH:D006943 Hyperglycemia pirinixic acid 3.4520558911
MESH:D006973 Hypertension Cyclosporine 2.1810903974
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.9816612254
MESH:D007333 Insulin Resistance pirinixic acid 2.8016306350
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.8815604871
MESH:D007674 Kidney Diseases Cyclosporine 2.488314463 10903974 18776723
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.0616705839
MESH:D007680 Kidney Neoplasms Cyclosporine 8.0612371664
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1916294345 17596541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 4.707678174
MESH:D008113 Liver Neoplasms pirinixic acid 4.7016377806 20007298 15890375
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.706135515 2876784 2876786
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.7017228818
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.2316801185
MESH:D008881 Migraine Disorders Valproic Acid 3.3818803445 18765137
MESH:D009135 Muscular Diseases pirinixic acid 3.8616239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.318888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3017596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.2419151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1616411023
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.2618551238 7678174
MESH:D009369 Neoplasms pirinixic acid 2.0617405874
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.8817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5319348381 18481113
MESH:D009436 Neural Tube Defects Valproic Acid 3.3016359493 8888407
MESH:D009765 Obesity pirinixic acid 1.8620558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.7016049721
MESH:D011230 Precancerous Conditions Cyclosporine 3.4712371664
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.2320603192
MESH:D011471 Prostatic Neoplasms Clorgyline 4.2419691856
MESH:D019310 Pseudolymphoma Valproic Acid 4.9811422049 12752131
MESH:D011565 Psoriasis Cyclosporine 2.3016882103
MESH:D015427 Reperfusion Injury pirinixic acid 2.5019058328
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.4819155313
MESH:D012559 Schizophrenia Valproic Acid 2.0915737665 19110320
MESH:D012640 Seizures 2,6-dinitrotoluene 6.5518551238
MESH:D012640 Seizures Valproic Acid 6.553137016 15475178 14763951 11738929 11044598 16876388 1511512 17978042
MESH:D016135 Spinal Dysraphism Valproic Acid 3.9919490988
MESH:D013226 Status Epilepticus Valproic Acid 4.9812833885
MESH:D014178 Translocation, Genetic Valproic Acid 5.6817262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.923119515
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.3816049721
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.008888407
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.7110091137
MESH:D014605 Uveitis Cyclosporine 4.431336536
MESH:D014985 Xerophthalmia Cyclosporine 4.8817120751
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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