AutismKB 2.0

Annotation Detail for PPP2R3B


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Basic Information Top
Gene Symbol:PPP2R3B ( FLJ60425,NYREN8,PPP2R3L,PPP2R3LY,PR48 )
Gene Full Name: protein phosphatase 2, regulatory subunit B'', beta
Band: Xp22.3 and Yp11.3
Quick LinksEntrez ID:28227; OMIM: 300339; Uniprot ID:P2R3B_HUMAN; ENSEMBL ID: ENSG00000167393; HGNC ID: 13417
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D004390 Chlorpyrifos Chlorpyrifos results in increased expression of PPP2R3B proteinincreases expression 16790487
C052570 cyfluthrin cyfluthrin results in increased expression of PPP2R3B proteinincreases expression 16790487
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000382 Agricultural Workers' Diseases Chlorpyrifos 5.2216611668 17119214 11874814
MESH:D008107 Liver Diseases Chlorpyrifos 3.1615991261
MESH:D020258 Neurotoxicity Syndromes Chlorpyrifos 4.4815081274
MESH:D012135 Respiratory Sounds Chlorpyrifos 5.4011874814 17119214 16611668
MESH:D012140 Respiratory Tract Diseases Chlorpyrifos 5.9616611668 17119214
MESH:D012729 Sex Chromosome Aberrations Chlorpyrifos 7.166418539
Pathway ID Pathway Name
KEGG:03015 mRNA surveillance pathway
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018