AutismKB 2.0

Annotation Detail for SLCO3A1


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Basic Information Top
Gene Symbol:SLCO3A1 ( FLJ40478,OATP-D,OATP3A1,OATPD,SLC21A11 )
Gene Full Name: solute carrier organic anion transporter family, member 3A1
Band: 15q26.1
Quick LinksEntrez ID:28232; OMIM: 612435; Uniprot ID:SO3A1_HUMAN; ENSEMBL ID: ENSG00000176463; HGNC ID: 10952
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Transmembrane transport of small molecules
No data
No data
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
response to iloperidone treatment (QT prolongation)
inattentive symptoms
PSYCH
PHARMACOGENOMIC
Desease Name
Response to iloperidone treatment (QT prolongation)
Inattentive symptoms
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023035 3,4,5,3',4'-pentachlorobiphenyl 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLCO3A1 mRNAincreases expression 15919853
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of SLCO3A1 mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of SLCO3A1 mRNAaffects expression 17562736
C006632 arsenic trioxide arsenic trioxide results in increased expression of SLCO3A1 mRNAincreases expression 15761015
D019324 beta-Naphthoflavone beta-Naphthoflavone results in increased expression of SLCO3A1 mRNAincreases expression 15919853
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of SLCO3A1 mRNAdecreases expression 20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SLCO3A1 mRNAdecreases expression 19150397
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of SLCO3A1 mRNAaffects expression 17484886
D004958 Estradiol [Progesterone co-treated with Estradiol] results in decreased expression of SLCO3A1 mRNAaffects cotreatment|decreases expression 17404688
D005419 Flavonoids Flavonoids results in decreased expression of SLCO3A1 mRNAdecreases expression 18035473
D011374 Progesterone [Progesterone co-treated with Estradiol] results in decreased expression of SLCO3A1 mRNAaffects cotreatment|decreases expression 17404688
D014050 Toluene Toluene affects the expression of SLCO3A1 mRNAaffects expression 18653662
D014212 Tretinoin Tretinoin results in decreased expression of SLCO3A1 mRNAdecreases expression 16604517
D014635 Valproic Acid Valproic Acid results in increased expression of SLCO3A1 mRNAincreases expression 19101580
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 3.578875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.9819490988
MESH:D000230 Adenocarcinoma arsenic trioxide 7.1411798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 7.1420127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 7.1411473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 11.373712494
MESH:D000236 Adenoma Benzo(a)pyrene 11.376695378
MESH:D000236 Adenoma beta-Naphthoflavone 11.3719389873
MESH:D018248 Adenoma, Liver Cell 3,4,5,3',4'-pentachlorobiphenyl 5.3116628245
MESH:D000505 Alopecia Tretinoin 3.6615955085
MESH:D000550 Amblyopia Valproic Acid 5.3317688650
MESH:D000799 Angioedema Acetaminophen 3.9410982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.6217497229
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.1519183758
MESH:D001169 Arthritis, Experimental Tretinoin 3.1116412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2716292516
MESH:D001249 Asthma Tretinoin 2.3616456186
MESH:D001321 Autistic Disorder Acetaminophen 1.8518445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8518775368 18940202 17157402 18558336 17688650 20603192 18316065 15238991 16609825 18396377 17507914 19232924 18177632 18985861 19460635
MESH:D001471 Barrett Esophagus Tretinoin 4.4716935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.121440618 11289319
MESH:D001714 Bipolar Disorder Valproic Acid 3.1020046352 17594078
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 9.3516206674
MESH:D001778 Blood Coagulation Disorders Tretinoin 9.3516197459 16206674
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.438888407
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.4317868700
MESH:D001930 Brain Injuries Progesterone 4.3315845082 15665606 15380490
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9620146248 17474063
MESH:D001943 Breast Neoplasms Estradiol 1.9617289903 18497071 12948864 14630087 16675129 17018787 17261762 19861407
MESH:D001943 Breast Neoplasms Progesterone 1.9617614352 15562024 16175315
MESH:D001943 Breast Neoplasms Tretinoin 1.9616166294 16873071 16443354
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.6716813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.3911589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.5516111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.8516097048 15700767 3786805 15673190 16124888 16050911 16011737 16227642 10355542 16192424 18705752 15721981
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2616168501
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 11.517296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.513084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.5111135700 16217749 14691202 15073043 15553829
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 11.5118788625
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.5116924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.511917145
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.9719014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.707296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.1712490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.6220419170
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.6216096774 16051514
MESH:D002386 Cataract Acetaminophen 7.3310977129
MESH:D002386 Cataract Tretinoin 7.3317460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 11.397505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.3920889678
MESH:D002471 Cell Transformation, Neoplastic Estradiol 11.3918566989
MESH:D002547 Cerebral Palsy Toluene 5.939294310
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.6716129372
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.7220734317
MESH:D018281 Cholangiocarcinoma 3,4,5,3',4'-pentachlorobiphenyl 5.0616628245
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.1919486331 9022650
MESH:D002822 Choriocarcinoma Tretinoin 5.2616461808
MESH:D002972 Cleft Palate Tretinoin 2.699407595
MESH:D003092 Colitis Tretinoin 3.7817035595
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.2512609071
MESH:D019465 Craniofacial Abnormalities 3,4,5,3',4'-pentachlorobiphenyl 7.4417686920
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 7.4410525206
MESH:D019465 Craniofacial Abnormalities Toluene 7.449294310
MESH:D019465 Craniofacial Abnormalities Tretinoin 7.449125849 17551590 9664655 16925845 9142499 10589399 9211117 14991402 9224671 8800419
MESH:D019465 Craniofacial Abnormalities Valproic Acid 7.4416575769 8888407 17688650
MESH:D003643 Death Toluene 5.766431079
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.1515213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.8711298694 11906362 18759878 2524372 8156756 14531868 8970840 12868966
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.553621924 2952479
MESH:D003928 Diabetic Nephropathies Estradiol 3.4619279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.5617187935
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 9.1018648102 9022650 18692083 7440962 8291058 6679447 18289764 6482804 16192314 11289319 9328219 9653073 1440618
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.1010663392 16227642 17522070 17906064 19420014 14725611 12594235 11834606 12392966 16781746 16485898 18071297 10774834 14986274 19923254 12705907 19164858 19416960 16393943 18713872 15619225 15968718 17562736 12153990 19370779 12958197 11529661 16177239 11421492 16081117 2444490 10915739 11461765 12540782 16109766 11287661 11739529 19739265 19085960 11743745 14550746
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 9.107179309 11566570 2869522 15998439 15027814 6623471 21278145 16177239 10092053 4309450 6884620 19336974 3732212 17522070 15968718 7440962 7120509 19085960 16227642 9327722 3786805 10915739
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 9.101733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1919426721
MESH:D004421 Dystonia Valproic Acid 4.111851702
MESH:D004489 Edema, Cardiac 3,4,5,3',4'-pentachlorobiphenyl 12.9517686920
MESH:D004489 Edema, Cardiac Tretinoin 12.9518230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 3.8417692515
MESH:D016889 Endometrial Neoplasms Estradiol 7.5311473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Tretinoin 7.5316569247
MESH:D004715 Endometriosis Progesterone 3.8216134523
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.233659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 4.0116628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.9618234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.637562514 6254150 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.377750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.153659116
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 10.493581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.4920426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 10.4912903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 10.4916530937
MESH:D005124 Eye Abnormalities Tretinoin 3.6216938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 13.5015073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 13.5012795759 12631006 61145 16239168 19224547 15959796 16045604 17595544
MESH:D005234 Fatty Liver Valproic Acid 13.5014986274 19224547
MESH:D005315 Fetal Diseases Valproic Acid 4.9816575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.198888407 18558336
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.126705139
MESH:D005355 Fibrosis Carbon Tetrachloride 9.0518705752
MESH:D005355 Fibrosis Tretinoin 9.0517994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.3316904648
MESH:D005756 Gastritis Acetaminophen 3.7716983495
MESH:D005909 Glioblastoma Tretinoin 3.0417312396
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.107505956
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.2216096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2616084493
MESH:D006330 Heart Defects, Congenital 3,4,5,3',4'-pentachlorobiphenyl 11.5020471113 17686920
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 11.5020471113
MESH:D006330 Heart Defects, Congenital Tretinoin 11.509664655 14991402
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 9.446705139
MESH:D006505 Hepatitis Carbon Tetrachloride 9.4419900420 19110552
MESH:D006558 Herpes Genitalis Estradiol 5.1315709030
MESH:D019584 Hot Flashes Estradiol 3.8517088409
MESH:D006849 Hydrocephalus Valproic Acid 4.9517688650
MESH:D006930 Hyperalgesia Acetaminophen 7.7716870215
MESH:D006930 Hyperalgesia Tretinoin 7.7716870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.6116899240
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6416778211
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.0115034207
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.1615338365
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.4715869954
MESH:D007249 Inflammation Flavonoids 5.3617296493
MESH:D007249 Inflammation Progesterone 5.3615869954
MESH:D007333 Insulin Resistance Estradiol 3.0016627594 16393666
MESH:D007410 Intestinal Diseases Tretinoin 3.8417994277
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.129022650 8074119
MESH:D007569 Jaw Abnormalities Tretinoin 3.9515992940 17551590
MESH:D007674 Kidney Diseases Acetaminophen 5.9812587719 15629191
MESH:D007674 Kidney Diseases Estradiol 5.9815618244
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 7.516582329
MESH:D007680 Kidney Neoplasms Estradiol 7.5115610895
MESH:D007938 Leukemia arsenic trioxide 6.4315070760
MESH:D007938 Leukemia Tretinoin 6.4317143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.8517077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.3916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.4714633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.6619077051
MESH:D007951 Leukemia, Myeloid Tretinoin 9.6616482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 6.1816467208 17050201 16968895 19850784 20471514
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 6.1817596541 16294345 19850784
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 6.1817596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.7516112521 12712474 19035177 11161223 16966277 17217047 11468182 16330433 16823087 16331271 9834237 19642359 19075265 12018890 15622746 17712046 17869043 15336539 15213294 15748426 16891316 17107899 12679006 19225113 17649720
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.7516766008 16788101 17107899 17506722 17368321 17649720 16140955 19029980 17339181 17301526 17217047 16823087 16331271 16891316 17712046 17294898 15748426 19035177 16935935 19642359 19225113 19075265 17361223 9834237 12679006
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.4216882451
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.349224671
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.8317334410 11903743 17174718 17157831 16239168 21278145 16221502 11408273 16943688
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.239327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 3.5418054572 17766677 16638106 16248980 16015684 18395095 15925388 12609069 17565644 15996030 15959796 12546737 14620537 17805973 17823541 15673190 17481882 12741479 18263696 18429990 15052691 18395914 16136751 18412020 18006644 12586293 15370692 16033810 17761835 15876570 15931870 12445421 14716496 17640975 18472094 15338365 12649538 18251166 17698563 13678700 14512876 18205269 17869086 17557913 14748882 15730626 17976157 18156304 12666154 14716833 17922224 18418968 12445418 17900296 18317297 18210741 12389079 15893842 15818738 18376398 17708605 17944888 16116963 12632514 16011737 15650968 18277467 17714472 18472332 15057751 18705752 12958196 10355542 17721639 12898905 18166357 18481824 17631135 12632512 16192424 12667390 16097048 18279442 11481614 18187930 18339082 16027843 18420326 15362042 15123356 20821823 14724832 17525996
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 3.5414659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 3.5418397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 3.9419784758 16611625 16610002 11587558 19460945 19014921 12587719 12969438
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.9416246199 16964402 15830285 17285989 15720792
MESH:D017093 Liver Failure Carbon Tetrachloride 4.2415123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.5816871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.5814706259 16899240
MESH:D008113 Liver Neoplasms arsenic trioxide 10.9014682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 10.9020195826 21137059
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 10.9019389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 10.9019294768
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 14.44598648 6587162 1399818 3712494
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 14.4420377131
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 14.4418164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 14.4412014681 15583823
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3915213294
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.3617228818
MESH:D008175 Lung Neoplasms arsenic trioxide 2.4319825857 11798837
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.4317053015 20135361 18520028 20869020 20464547 20064080 6695378 18816296 18569708
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 6.1711807958 17203775 16891317 11408345
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 6.1717203775 11408345
MESH:D020149 Manganese Poisoning Estradiol 4.5819453300
MESH:D008527 Medulloblastoma Tretinoin 2.8017453147
MESH:D008545 Melanoma Tretinoin 1.9516752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6419513568
MESH:D008591 Meningomyelocele Tretinoin 4.5016940565
MESH:D008607 Mental Retardation Toluene 3.679294310
MESH:D008881 Migraine Disorders Valproic Acid 3.2318765137 18803445
MESH:D019957 Motor Skills Disorders Toluene 5.299294310
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.2316381670
MESH:D009101 Multiple Myeloma arsenic trioxide 3.1415949261 11468182 19417148 14977855 19549372
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.088888407
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.7718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 12.4816882451 16105982
MESH:D009190 Myelodysplastic Syndromes Tretinoin 12.4817596541
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 12.4817596541
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.3216810080
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.0216624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.493581430
MESH:D009369 Neoplasms Benzo(a)pyrene 5.0711141357
MESH:D009369 Neoplasms Tretinoin 5.0716946489 16594593
MESH:D009389 Neovascularization, Pathologic Estradiol 3.8117289903
MESH:D009421 Nervous System Malformations Estradiol 9.8911399458 16427766
MESH:D009421 Nervous System Malformations Tretinoin 9.899125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 17.626679447
MESH:D009436 Neural Tube Defects arsenic trioxide 17.6210525206
MESH:D009436 Neural Tube Defects Tretinoin 17.629142499
MESH:D009436 Neural Tube Defects Valproic Acid 17.628888407 16359493
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.9118514411
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.474026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.123988306
MESH:D010051 Ovarian Neoplasms arsenic trioxide 11.4319769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Estradiol 11.4319401270
MESH:D010051 Ovarian Neoplasms Progesterone 11.4317393432 16525653
MESH:D010051 Ovarian Neoplasms Tretinoin 11.4316936753
MESH:D010146 Pain Acetaminophen 6.7416870215
MESH:D010146 Pain Tretinoin 6.7416870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 5.3515580305
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.3515976015
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.557296757
MESH:D010235 Paraganglioma arsenic trioxide 4.2219927285
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.576228378
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 3.9120603192
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.9420887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.5119131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.5117292933
MESH:D011471 Prostatic Neoplasms Estradiol 2.5116740699
MESH:D011507 Proteinuria Tretinoin 3.6616636307
MESH:D019310 Pseudolymphoma Valproic Acid 4.6412752131 11422049
MESH:D011625 Pterygium Tretinoin 4.8816723453
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.413692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 11.0616283617 16116481
MESH:D012208 Rhabdomyosarcoma Valproic Acid 11.0619155313
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.8718045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.0216646077
MESH:D012559 Schizophrenia Valproic Acid 2.0719110320 15737665
MESH:D012640 Seizures Toluene 6.506431079 9294310
MESH:D012640 Seizures Valproic Acid 6.5017978042 11044598 15475178 14763951 16876388 3137016 1511512 11738929
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.7619755658 10029692
MESH:D012878 Skin Neoplasms Tretinoin 5.7616467112
MESH:D013119 Spinal Cord Injuries Progesterone 4.3616503802 15862959
MESH:D016135 Spinal Dysraphism Valproic Acid 3.8219490988
MESH:D013226 Status Epilepticus Valproic Acid 4.6412833885
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.3717007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.3720155912 2093021
MESH:D013274 Stomach Neoplasms Tretinoin 3.3717261132
MESH:D013733 Testicular Diseases Toluene 5.0410514026 10048760
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 12.213712494 6582329 1399818 6587162 7505956
MESH:D013964 Thyroid Neoplasms arsenic trioxide 12.2119014326
MESH:D013964 Thyroid Neoplasms Tretinoin 12.2117045167 16026305
MESH:D013978 Tibial Fractures Estradiol 4.7819048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.8416051514
MESH:D016171 Torsades de Pointes arsenic trioxide 4.0415213294
MESH:D014178 Translocation, Genetic Valproic Acid 5.3317262798
MESH:D014376 Tuberculosis Tretinoin 3.2616040207
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.603119515
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 8.418074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.4111780464 12973940 20435036 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.4117053015
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.718888407
MESH:D014581 Urticaria Acetaminophen 3.0310982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.7316129372
MESH:D014604 Uveal Neoplasms Tretinoin 4.7116752155
MESH:D014820 Vitiligo Tretinoin 4.1216761959
MESH:D009396 Wilms Tumor Tretinoin 4.0216287080
Pathway ID Pathway Name
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35837
    • Releated gene ID Related gene Name
    PA35837SLCO3A1
    Releated disease ID Related disease Name
    PA447300Acquired Long QT Syndrome (aLQTS)
    PA447228congenital long QT syndrome
    PA444807Long QT Syndrome
    PA447300Acquired Long QT Syndrome (aLQTS)
    Releated drug ID Related drug Name
    PA449512estrone
    PA450842penicillin g
    PA151070295thyroxine
    PA451858vasopressin
    PA161199368iloperidone
    PA161199368iloperidone
    Drug Bank Top
    No data
    No data
    Drugbank ID Action Drug Name Description
    DB00286 substrate Prempro Estrogens
    DB00345 inhibitor Aminohippurate Diagnostic aids;Indicators and Reagents
    DB00563 substrate Methotrexate Antineoplastic Agents;Antirheumatic Agents;Antimetabolites;Enzyme Inhibitors;Folic Acid Antagonists;Dermatologic Agents;Immunosuppressive Agents;Nucleic Acid Synthesis Inhibitors;Abortifacient Agents, Nonsteroidal;Abortifacient Agents;Antimetabolites, Antineoplastic
    DB00770 inhibitor Caverject Sterile Powder - Kit 23.2mcg/Vial Vasodilator Agents;Platelet Aggregation Inhibitors;Fibrinolytic Agents
    DB00917 substrate Dinoprostone Oxytocics;Prostaglandins
    DB01053 substrate Penicillin G Anti-Bacterial Agents;Penicillins
    DB01088 substrate Iloprost Antihypertensive Agents
    DB04348 inhibitor Taurocholic Acid Cholagogues and Choleretics;Detergents
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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