AutismKB 2.0

Annotation Detail for RASSF3


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Basic Information Top
Gene Symbol:RASSF3 ( MGC119194,MGC119195,MGC119197,RASSF5 )
Gene Full Name: Ras association (RalGDS/AF-6) domain family member 3
Band: 12q14.2
Quick LinksEntrez ID:283349; OMIM: 607019; Uniprot ID:RASF3_HUMAN; ENSEMBL ID: ENSG00000153179; HGNC ID: 14271
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of RASSF3 mRNAaffects expression 17562736
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of RASSF3 mRNAaffects expression 17484886
D004041 Dietary Fats Dietary Fats results in increased expression of RASSF3 mRNAincreases expression 18042831
D002117 Calcitriol Calcitriol results in increased expression of RASSF3 mRNAincreases expression 16002434
C011890 kojic acid kojic acid results in increased expression of RASSF3 mRNAincreases expression 16595896
C406082 monomethylarsonous acid monomethylarsonous acid results in decreased expression of RASSF3 mRNAdecreases expression 20024957
C041786 palm oil palm oil results in increased expression of RASSF3 mRNAincreases expression 18042831
C006253 pirinixic acid pirinixic acid results in increased expression of RASSF3 mRNAincreases expression 18301758
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.3818653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.8216434500
MESH:D000799 Angioedema Acetaminophen 4.2210982225
MESH:D001161 Arteriosclerosis Dietary Fats 4.1915238619
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.3919483382
MESH:D001943 Breast Neoplasms Calcitriol 2.2911237771
MESH:D001943 Breast Neoplasms Dietary Fats 2.2920435547
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.0815721981 16124888 18705752 10355542 15700767 16011737 15673190 16192424 16227642 16050911 3786805 16097048
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.943084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 2.9418788625
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 2.6811237771
MESH:D002386 Cataract Acetaminophen 2.7110977129
MESH:D002471 Cell Transformation, Neoplastic monomethylarsonous acid 4.0819716837
MESH:D002779 Cholestasis pirinixic acid 3.0019176532
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5218249437
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.9419085960 16485898 15968718 12153990 11287661 16393943 15619225 18071297 19739265 11743745 16109766 17906064 16081117 17562736 17522070 11529661 2444490 12392966 19164858 19370779 19416960 12540782 11834606 12705907 14986274 10663392 12958197 18713872 10915739 10774834 11461765 11739529 14725611 14550746 12594235 11421492 16227642 19923254 19420014 16177239 16781746
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 3.9411566570 16227642 6623471 6884620 3786805 10092053 7440962 10915739 16177239 21278145 19336974 15027814 7120509 7179309 19085960 9327722 15998439 15968718 3732212 4309450 2869522 17522070
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.4719426721
MESH:D050171 Dyslipidemias Dietary Fats 3.6218367378
MESH:D004487 Edema pirinixic acid 2.7212083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 4.2115138306
MESH:D005234 Fatty Liver Carbon Tetrachloride 14.5616045604 16239168 15959796 17595544 12631006 12795759 61145 19224547
MESH:D005234 Fatty Liver Dietary Fats 14.5617967931 19004024 18296743 19551842
MESH:D005234 Fatty Liver pirinixic acid 14.5619236843 20131406
MESH:D005355 Fibrosis Carbon Tetrachloride 9.8518705752
MESH:D005355 Fibrosis Dietary Fats 9.8518296743
MESH:D005756 Gastritis Acetaminophen 4.0516983495
MESH:D006333 Heart Failure pirinixic acid 2.6720558911
MESH:D006505 Hepatitis Carbon Tetrachloride 3.8819900420 19110552
MESH:D006529 Hepatomegaly pirinixic acid 3.3019176532 18467677 16221962 19772884
MESH:D006930 Hyperalgesia Acetaminophen 2.8916870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.8716899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.8321332399
MESH:D006943 Hyperglycemia pirinixic acid 3.4120558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.8721332399
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.3915338365
MESH:D007249 Inflammation Dietary Fats 2.5420412841
MESH:D007333 Insulin Resistance Dietary Fats 7.7418457598 11836018
MESH:D007333 Insulin Resistance pirinixic acid 7.7416306350
MESH:D007674 Kidney Diseases Acetaminophen 2.3215629191 12587719
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 7.0317157831 11408273 21278145 11903743 17334410 16943688 16221502 17174718 16239168
MESH:D008103 Liver Cirrhosis Dietary Fats 7.0318296743
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 2.3815959796 17761835 16136751 18279442 18472094 15996030 14724832 16015684 12445421 15925388 17640975 17557913 16033810 12741479 18705752 16248980 15057751 15730626 16116963 18210741 18317297 17805973 17944888 12546737 18420326 18205269 17565644 17708605 15052691 18054572 18263696 18006644 18481824 17823541 18277467 17714472 17766677 15818738 15123356 12389079 15931870 18429990 18166357 18395914 18395095 12445418 18339082 14512876 15362042 14620537 13678700 14716496 17922224 12898905 17900296 18412020 17869086 12666154 14716833 10355542 15876570 17721639 18418968 18251166 16097048 15673190 17976157 17698563 18156304 15370692 18472332 16027843 20821823 15338365 12958196 12586293 17481882 12632514 16638106 18376398 14748882 11481614 12609069 12667390 18187930 15893842 15650968 17631135 16192424 12632512 16011737 12649538 17525996
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.3815474484
MESH:D008107 Liver Diseases Acetaminophen 4.0719784758 19460945 11587558 12969438 16610002 16611625 12587719 19014921
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.0715720792 17285989 15830285 16964402 16246199
MESH:D017093 Liver Failure Carbon Tetrachloride 4.4715123358
MESH:D017114 Liver Failure, Acute Acetaminophen 10.1816871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 10.1816899240 14706259
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 4.6919294768
MESH:D008113 Liver Neoplasms pirinixic acid 4.6915890375 20007298 16377806
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 6.6815583823 12014681
MESH:D008114 Liver Neoplasms, Experimental kojic acid 6.6818544905
MESH:D008546 Melanoma, Experimental Acetaminophen 3.8719513568
MESH:D009135 Muscular Diseases pirinixic acid 3.8116239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2219151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1316411023
MESH:D009369 Neoplasms pirinixic acid 2.0517405874
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.0718514411
MESH:D009765 Obesity Dietary Fats 4.6020132043 20518802 11836018 18674790 17217161 16723640 21332399 18457598 19632207
MESH:D009765 Obesity pirinixic acid 4.6020558911
MESH:D010146 Pain Acetaminophen 2.5916870215
MESH:D011470 Prostatic Hyperplasia Calcitriol 5.1215572423
MESH:D011471 Prostatic Neoplasms Calcitriol 3.5012479363 16289102 15754350 18247401 16644109
MESH:D015427 Reperfusion Injury pirinixic acid 2.4919058328
MESH:D012871 Skin Diseases monomethylarsonous acid 3.4317431481
MESH:D001749 Urinary Bladder Neoplasms monomethylarsonous acid 3.5220375083
MESH:D014581 Urticaria Acetaminophen 3.2410982225
MESH:D015430 Weight Gain Dietary Fats 3.9516723640
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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