Annotation Detail for GPR133
Basic Information Top
| Gene Symbol: | GPR133 ( DKFZp434B1272,FLJ16770,MGC138512,MGC138514,PGR25 ) |
|---|---|
| Gene Full Name: | G protein-coupled receptor 133 |
| Band: | 12q24.33 |
| Quick Links | Entrez ID:283383; OMIM: NA; Uniprot ID:GP133_HUMAN; ENSEMBL ID: ENSG00000111452; HGNC ID: |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| No data |
| No data |
| Desease Name |
|---|
| CARDIOVASCULAR |
| protein quantitative trait loci |
| height |
| RR interval (heart rate) |
| DEVELOPMENTAL |
| Desease Name |
|---|
| Height |
| Protein quantitative trait loci |
| RR interval (heart rate) |
| No data |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000638 | Amiodarone | Amiodarone results in increased expression of GPR133 mRNA | increases expression | 19774075 |
| D004041 | Dietary Fats | Dietary Fats results in decreased expression of GPR133 mRNA | decreases expression | 18042831 |
| C041786 | palm oil | palm oil results in decreased expression of GPR133 mRNA | decreases expression | 18042831 |
| C006253 | pirinixic acid | pirinixic acid results in increased expression of GPR133 mRNA | increases expression | 17426115 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 3.58 | 18653653 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 4.11 | 16434500 | |
| MESH:D001145 | Arrhythmias, Cardiac | Amiodarone | 4.20 | 18218290 18057881 20041841 | |
| MESH:D001161 | Arteriosclerosis | Dietary Fats | 4.45 | 15238619 | |
| MESH:D001281 | Atrial Fibrillation | Amiodarone | 4.20 | 19698954 18651412 | |
| MESH:D001778 | Blood Coagulation Disorders | Amiodarone | 10.53 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 10.53 | 19483382 | |
| MESH:D001943 | Breast Neoplasms | Dietary Fats | 2.24 | 20435547 | |
| MESH:D002311 | Cardiomyopathy, Dilated | Amiodarone | 3.00 | 19225199 15710769 | |
| MESH:D002341 | Carotid Artery Thrombosis | Amiodarone | 5.72 | 18974383 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 3.12 | 19176532 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.57 | 18249437 | |
| MESH:D056486 | Drug-Induced Liver Injury | Amiodarone | 2.47 | 15265979 18218290 | |
| MESH:D050171 | Dyslipidemias | Dietary Fats | 3.73 | 18367378 | |
| MESH:D004487 | Edema | pirinixic acid | 2.90 | 12083418 | |
| MESH:D005234 | Fatty Liver | Amiodarone | 15.74 | 14986274 | |
| MESH:D005234 | Fatty Liver | Dietary Fats | 15.74 | 17967931 18296743 19004024 19551842 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 15.74 | 19236843 20131406 | |
| MESH:D005355 | Fibrosis | Dietary Fats | 4.08 | 18296743 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 2.76 | 20558911 | |
| MESH:D006529 | Hepatomegaly | Amiodarone | 10.51 | 15265979 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 10.51 | 19772884 18467677 16221962 19176532 | |
| MESH:D006937 | Hypercholesterolemia | Amiodarone | 10.62 | 9751232 8137927 | |
| MESH:D006937 | Hypercholesterolemia | Dietary Fats | 10.62 | 21332399 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 3.58 | 20558911 | |
| MESH:D006949 | Hyperlipidemias | Dietary Fats | 4.08 | 21332399 | |
| MESH:D007037 | Hypothyroidism | Amiodarone | 5.08 | 17991464 18020914 | |
| MESH:D007249 | Inflammation | Dietary Fats | 2.60 | 20412841 | |
| MESH:D007333 | Insulin Resistance | Dietary Fats | 8.06 | 18457598 11836018 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 8.06 | 16306350 | |
| MESH:D008064 | Lipidoses | Amiodarone | 3.79 | 17567588 15342952 | |
| MESH:D008103 | Liver Cirrhosis | Dietary Fats | 3.07 | 18296743 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 1.35 | 15474484 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 1.93 | 20007298 15890375 16377806 | |
| MESH:D008133 | Long QT Syndrome | Amiodarone | 3.89 | 15350150 11989578 17391786 | |
| MESH:D008171 | Lung Diseases | Amiodarone | 3.62 | 12587719 | |
| MESH:D017563 | Lung Diseases, Interstitial | Amiodarone | 5.20 | 18516814 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 4.07 | 16239165 | |
| MESH:D009181 | Mycoses | Amiodarone | 5.62 | 17974566 12754197 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 2.27 | 19151258 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 3.25 | 16411023 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 2.11 | 17405874 | |
| MESH:D009765 | Obesity | Dietary Fats | 4.69 | 11836018 17217161 19632207 18674790 18457598 21332399 16723640 20132043 20518802 | |
| MESH:D009765 | Obesity | pirinixic acid | 4.69 | 20558911 | |
| MESH:D011658 | Pulmonary Fibrosis | Amiodarone | 2.97 | 12490602 12832656 11597910 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.55 | 19058328 | |
| OMIM:609620 | SHORT QT SYNDROME 1 | Amiodarone | 5.72 | 18724381 | |
| MESH:D013276 | Stomach Ulcer | Amiodarone | 3.74 | 18087811 | |
| MESH:D013610 | Tachycardia | Amiodarone | 4.80 | 11238279 | |
| MESH:D017180 | Tachycardia, Ventricular | Amiodarone | 4.70 | 19225199 | |
| MESH:D013959 | Thyroid Diseases | Amiodarone | 5.48 | 19731979 | |
| MESH:D013971 | Thyrotoxicosis | Amiodarone | 5.42 | 18020914 19584973 | |
| MESH:D016171 | Torsades de Pointes | Amiodarone | 4.82 | 17467628 11989578 | |
| MESH:D015430 | Weight Gain | Dietary Fats | 4.11 | 16723640 |
| No data |