Annotation Detail for SLC13A5
Basic Information
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| Gene Symbol: | SLC13A5 ( DKFZp686E17257,MGC138356,NACT ) |
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| Gene Full Name: | solute carrier family 13 (sodium-dependent citrate transporter), member 5 |
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| Band: | 17p13.1 |
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| Quick Links | Entrez ID:284111; OMIM: 608305; Uniprot ID:S13A5_HUMAN; ENSEMBL ID: ENSG00000141485; HGNC ID: 23089 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| Transmembrane transport of small molecules |
| Bile salt and organic anion SLC transporters |
| Pathway ID | Pathway Name |
|---|
| 500002 | Sodium-coupled sulphate, di- and tri-carboxylate transporters |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of SLC13A5 mRNA | affects expression | 21346803
|
| D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of SLC13A5 mRNA | affects expression | 16483693
|
| D019324 |
beta-Naphthoflavone |
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLC13A5 mRNA | affects cotreatment|decreases expression | 18164116
|
| D004052 |
Diethylnitrosamine |
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLC13A5 mRNA | affects cotreatment|decreases expression | 18164116
|
| D014050 |
Toluene |
Toluene affects the expression of SLC13A5 mRNA | affects expression | 18653662
|
| D014415 |
Tunicamycin |
Tunicamycin results in increased expression of SLC13A5 mRNA | increases expression | 17127020
|
| C025643 |
vinclozolin |
vinclozolin affects the expression of SLC13A5 mRNA | affects expression | 19015723
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
3.95 | 18287403 |
| MESH:D000236 |
Adenoma |
|
beta-Naphthoflavone |
7.37 | 19389873 |
| MESH:D000236 |
Adenoma |
|
Diethylnitrosamine |
7.37 | 10737359 6695378 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
Diethylnitrosamine |
4.30 | 19061943 19052882 17620307 18056438 16434500 17162532 |
| MESH:D001008 |
Anxiety Disorders |
|
vinclozolin |
3.86 | 19015723 |
| MESH:D001943 |
Breast Neoplasms |
|
Diethylnitrosamine |
2.20 | 17474063 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
3.10 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Diethylnitrosamine |
3.10 | 17162532 17978847 16807293 20727157 18691550 19539802 18494052 3084413 20512989 19701751 18785209 20214788 19919837 17173139 10672840 16779866 16681979 21159647 20432363 19822196 19335982 19052882 18978308 18393292 16502159 16569478 18788625 20007298 20514400 17138121 10737359 18210153 19394651 16288022 20084675 19171122 16328049 18506893 19418558 16935385 18665156 19208518 19519916 17761372 16698587 18971187 20935162 18056438 19107877 17428255 20101231 19383236 11831363 16878318 16830150 20524982 3581430 17055752 16540662 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Diethylnitrosamine |
3.04 | 21159647 7505956 2727394 17174075 |
| MESH:D002547 |
Cerebral Palsy |
|
Toluene |
6.25 | 9294310 |
| MESH:D018281 |
Cholangiocarcinoma |
|
Diethylnitrosamine |
3.93 | 19052882 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Toluene |
2.88 | 9294310 |
| MESH:D003456 |
Cryptorchidism |
|
vinclozolin |
4.67 | 14966744 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
4.37 | 18551238 |
| MESH:D003643 |
Death |
|
Toluene |
6.11 | 6431079 |
| MESH:D003924 |
Diabetes Mellitus, Type 2 |
|
Diethylnitrosamine |
2.24 | 20387270 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
4.11 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Diethylnitrosamine |
4.11 | 19107877 |
| MESH:D004931 |
Esophageal Achalasia |
|
Diethylnitrosamine |
5.56 | 16302075 |
| MESH:D005234 |
Fatty Liver |
|
Diethylnitrosamine |
3.46 | 20387270 21071580 |
| MESH:D030342 |
Genetic Diseases, Inborn |
|
vinclozolin |
5.33 | 16973722 |
| MESH:D005832 |
Genital Diseases, Male |
|
vinclozolin |
5.74 | 16417039 |
| MESH:D007248 |
Infertility, Male |
|
vinclozolin |
3.21 | 16467254 |
| MESH:D007249 |
Inflammation |
|
Diethylnitrosamine |
2.50 | 18785209 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
3.21 | 16705839 |
| MESH:D007984 |
Leydig Cell Tumor |
|
vinclozolin |
5.13 | 16417039 |
| MESH:D008103 |
Liver Cirrhosis |
|
Diethylnitrosamine |
2.96 | 18407596 18665156 18522880 20032147 19638242 |
| MESH:D008107 |
Liver Diseases |
|
Diethylnitrosamine |
2.15 | 17034775 |
| MESH:D008113 |
Liver Neoplasms |
|
beta-Naphthoflavone |
5.06 | 19389873 21295105 |
| MESH:D008113 |
Liver Neoplasms |
|
Diethylnitrosamine |
5.06 | 19426721 15885732 19812893 18978307 19427195 2422723 16942905 19850985 19073162 21167192 19690152 20434301 18644402 21071580 19294768 19090486 19833225 15175105 20452335 19642983 18754104 20501860 12112319 21047994 20137499 20118626 19638242 2862719 18977376 20492335 12771043 10737359 19499222 20101389 21278145 20405173 19551842 19256749 19254457 20583210 9163691 18648771 19255062 19996281 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
beta-Naphthoflavone |
6.67 | 18164116 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Diethylnitrosamine |
6.67 | 19519916 18775883 19539802 18093689 16267830 19126423 17942915 18544905 17854601 18079962 3124819 21159647 18308698 19004024 9362446 17174075 19009564 2563599 18282651 18253720 18164116 16842330 |
| MESH:D008175 |
Lung Neoplasms |
|
Diethylnitrosamine |
1.76 | 21163286 6695378 20970405 20512841 |
| MESH:D008607 |
Mental Retardation |
|
Toluene |
3.72 | 9294310 |
| MESH:D019957 |
Motor Skills Disorders |
|
Toluene |
5.54 | 9294310 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
4.25 | 18551238 |
| MESH:D009362 |
Neoplasm Metastasis |
|
Diethylnitrosamine |
2.66 | 9029167 3581430 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Diethylnitrosamine |
3.57 | 20387270 |
| MESH:D009461 |
Neurologic Manifestations |
|
Diethylnitrosamine |
5.56 | 20387270 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
3.69 | 16049721 12819281 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Diethylnitrosamine |
2.50 | 16540662 |
| MESH:D011230 |
Precancerous Conditions |
|
Diethylnitrosamine |
3.80 | 2563599 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
vinclozolin |
4.29 | 18042343 19015723 18220299 |
| MESH:D011469 |
Prostatic Diseases |
|
vinclozolin |
5.33 | 18220299 |
| MESH:D011472 |
Prostatitis |
|
vinclozolin |
5.33 | 18629315 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
6.91 | 18551238 |
| MESH:D012640 |
Seizures |
|
Toluene |
6.91 | 6431079 9294310 |
| MESH:D013274 |
Stomach Neoplasms |
|
Diethylnitrosamine |
1.76 | 18456281 |
| MESH:D013733 |
Testicular Diseases |
|
Toluene |
5.35 | 10514026 10048760 |
| MESH:D013964 |
Thyroid Neoplasms |
|
Diethylnitrosamine |
3.19 | 7505956 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
2.37 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
4.71 | 10091137 |
| Pathway ID |
Pathway Name |
|---|
| REACT:20633 |
Bile salt and organic anion SLC transporters |
| REACT:15518 |
Transmembrane transport of small molecules |
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