AutismKB 2.0

Annotation Detail for GPR34


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Basic Information Top
Gene Symbol:GPR34 ( - )
Gene Full Name: G protein-coupled receptor 34
Band: Xp11.4
Quick LinksEntrez ID:2857; OMIM: 300241; Uniprot ID:GPR34_HUMAN; ENSEMBL ID: ENSG00000171659; HGNC ID: 4490
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of GPR34 mRNAdecreases expression 20064835
C014347 decitabine decitabine affects the expression of GPR34 mRNAaffects expression 17145863
D007501 Iron Iron deficiency results in increased expression of GPR34 mRNAincreases expression 20368581
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0620127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.886695378
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 6.3916640825
MESH:D000544 Alzheimer Disease Iron 3.0716640825 16563566
MESH:D000740 Anemia Iron 4.8216566752 16434484
MESH:D018798 Anemia, Iron-Deficiency Iron 5.0917162259 17163184 16569441 17375513 17147795
MESH:D000756 Anemia, Sideroblastic Iron 5.3016910769
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.7319183758
MESH:D001145 Arrhythmias, Cardiac Iron 4.8216604332
MESH:D001260 Ataxia Telangiectasia Iron 6.1915336622
MESH:D050197 Atherosclerosis Iron 3.9416632123 16640825
MESH:D001321 Autistic Disorder Iron 2.7617352947
MESH:D001424 Bacterial Infections Iron 5.9416640825
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.1817474063 20146248
MESH:D001943 Breast Neoplasms decitabine 2.1818320071 19208741
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 5.0120419170
MESH:D002294 Carcinoma, Squamous Cell decitabine 5.0119215824
MESH:D009202 Cardiomyopathies Iron 4.3116640825
MESH:D002311 Cardiomyopathy, Dilated Iron 3.5716604332
MESH:D003110 Colonic Neoplasms decitabine 4.3217616700
MESH:D003110 Colonic Neoplasms Iron 4.3216640825
MESH:D015179 Colorectal Neoplasms decitabine 2.1118981723
MESH:D003920 Diabetes Mellitus Iron 4.8716640825 16604332
MESH:D003922 Diabetes Mellitus, Type 1 Iron 3.4616506275
MESH:D003924 Diabetes Mellitus, Type 2 Iron 3.1716506275
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.9819294695
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0916530937
MESH:D005234 Fatty Liver Iron 4.5716640825
MESH:D005621 Friedreich Ataxia Iron 6.0816604332 16640825
MESH:D006258 Head and Neck Neoplasms decitabine 3.7719215824
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8520471113
MESH:D006432 Hemochromatosis Iron 4.8016574947 17236123 16640825 17255318 16604332 17053826
MESH:D006486 Hemosiderosis Iron 6.0816604332
MESH:D006525 Hepatitis, Viral, Human Iron 6.3416640825
MESH:D006527 Hepatolenticular Degeneration Iron 5.5917182432
MESH:D006529 Hepatomegaly Iron 4.9716890145
MESH:D015658 HIV Infections Iron 3.8716597321
MESH:D007006 Hypogonadism Iron 4.7016640825
MESH:D007037 Hypothyroidism Iron 5.7316640825
MESH:D007248 Infertility, Male decitabine 3.4817581917
MESH:D019189 Iron Metabolism Disorders Iron 5.5717163184
MESH:D007938 Leukemia decitabine 3.2519235587 18980019
MESH:D007951 Leukemia, Myeloid decitabine 4.4919117987 18454857 17236224
MESH:D015470 Leukemia, Myeloid, Acute decitabine 2.4318704418 18460780 19387464 19010910 18206229 17679729
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 6.3318055864
MESH:D020961 Lewy Body Disease Iron 6.0816563566
MESH:D008103 Liver Cirrhosis Iron 3.9316640825
MESH:D008108 Liver Diseases, Alcoholic Iron 5.6617207112 16737972
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 5.3021137059 20195826
MESH:D008113 Liver Neoplasms Iron 5.3016640825 20302851
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.8018520028 20464547 20135361 20064080 18569708 6695378 18816296 17053015 20869020
MESH:D008175 Lung Neoplasms Iron 2.8016640825
MESH:D008223 Lymphoma decitabine 3.7319470736
MESH:D008268 Macular Degeneration Iron 4.1916640825
MESH:D008545 Melanoma decitabine 2.2917785578 16505122
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5316381670
MESH:D009101 Multiple Myeloma decitabine 3.6518172295
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 6.5417086897
MESH:D009181 Mycoses Iron 6.3416640825
MESH:D009190 Myelodysplastic Syndromes decitabine 3.6016882708 19157545 18608210 19010910
MESH:D017202 Myocardial Ischemia Iron 4.8116604332
MESH:D015428 Myocardial Reperfusion Injury Iron 4.6116604332
MESH:D009369 Neoplasms Benzo(a)pyrene 5.7311141357
MESH:D009369 Neoplasms decitabine 5.7319470736 19116145 17925555
MESH:D009404 Nephrotic Syndrome Iron 4.9317178036
MESH:D019636 Neurodegenerative Diseases Iron 4.6316604332 17296847
MESH:D010003 Osteoarthritis Iron 4.2016640825
MESH:D010024 Osteoporosis Iron 4.1016640825 16648989
MESH:D010051 Ovarian Neoplasms decitabine 2.7519259094 19331143
MESH:D010190 Pancreatic Neoplasms decitabine 2.8919294695
MESH:D010212 Papilloma Iron 5.1312065085
MESH:D020447 Parasomnias Iron 6.8917352947
MESH:D010300 Parkinson Disease Iron 3.4516563566 16640825
MESH:D010900 Pituitary Diseases Iron 6.5416604332
MESH:D011041 Poisoning Iron 4.8216604332
MESH:D017119 Porphyria Cutanea Tarda Iron 5.5716640825
MESH:D011225 Pre-Eclampsia Iron 4.7716640825
MESH:D055728 Primary Myelofibrosis decitabine 5.3817616702
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9017292933
MESH:D011528 Protozoan Infections Iron 6.8916640825
MESH:D012148 Restless Legs Syndrome Iron 4.8716930377
MESH:D012208 Rhabdomyosarcoma decitabine 4.9319155313
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 6.5810029692 19755658
MESH:D012878 Skin Neoplasms Iron 6.5812065085
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.5420155912 2093021
MESH:D013274 Stomach Neoplasms decitabine 2.5419037991
MESH:D013398 Sudden Infant Death Iron 6.1916640825
MESH:D013964 Thyroid Neoplasms decitabine 3.6717967635
MESH:D014376 Tuberculosis Iron 4.3316597321
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.5917053015
MESH:D001749 Urinary Bladder Neoplasms decitabine 5.5917616700 19087683
MESH:D014604 Uveal Neoplasms decitabine 5.7817785578
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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