AutismKB 2.0

Annotation Detail for MKNK2


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Basic Information Top
Gene Symbol:MKNK2 ( GPRK7,MNK2 )
Gene Full Name: MAP kinase interacting serine/threonine kinase 2
Band: 19p13.3
Quick LinksEntrez ID:2872; OMIM: 605069; Uniprot ID:MKNK2_HUMAN; ENSEMBL ID: ENSG00000099875; HGNC ID: 7111
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04910Insulin signaling pathway
hsa04010MAPK signaling pathway
No data
No data
Pathway IDPathway Name
P00046Oxidative stress response
P00047PDGF signaling pathway
P00036Interleukin signaling pathway
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of MKNK2 mRNAaffects expression 17562736
15606129
C006632 arsenic trioxide arsenic trioxide results in increased phosphorylation of and results in increased activity of MKNK2 proteinincreases activity|increases phosphorylation 18299328
C006632 arsenic trioxide MAPK14 protein promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MKNK2 protein]increases activity|increases phosphorylation|increases reaction 18299328
C006632 arsenic trioxide MKNK2 protein promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of EIF4E protein]increases activity|increases phosphorylation|increases reaction 18299328
C006632 arsenic trioxide MKNK2 protein results in decreased susceptibility to arsenic trioxidedecreases response to substance 18299328
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MKNK2 mRNAaffects cotreatment|increases expression 18164116
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of MKNK2 mRNAdecreases expression 15336504
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of MKNK2 mRNAincreases expression 15003993
D004040 Dietary Carbohydrates Dietary Carbohydrates results in increased expression of MKNK2 mRNAincreases expression 17490981
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MKNK2 mRNAaffects cotreatment|increases expression 18164116
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of MKNK2 mRNAincreases expression 15289156
D004958 Estradiol Estradiol results in increased expression of MKNK2 mRNAincreases expression 15289156
D000431 Ethanol Ethanol results in decreased expression of MKNK2 mRNAdecreases expression 15513904
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of MKNK2 mRNAincreases expression 17942748
D019833 Genistein Genistein results in increased expression of MKNK2 mRNAincreases expression 15289156
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of MKNK2 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of MKNK2 mRNAincreases expression 19270015
19482888
D011374 Progesterone Progesterone results in increased expression of MKNK2 mRNAincreases expression 18037150
D019772 Topotecan MKNK2 protein affects the susceptibility to Topotecanaffects response to substance 16217747
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 8.9717676605 18926900
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 8.976195326
MESH:D000138 Acidosis Ethanol 4.5811192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0417505938
MESH:D000230 Adenocarcinoma arsenic trioxide 10.2919825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 10.2911473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.2914692618
MESH:D000230 Adenocarcinoma Genistein 10.2911473722
MESH:D000236 Adenoma beta-Naphthoflavone 6.9819389873
MESH:D000236 Adenoma Diethylnitrosamine 6.9810737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 10.5517162532 19061943 16434500 17620307 18056438 19052882
MESH:D018248 Adenoma, Liver Cell Phenobarbital 10.5517620307
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 5.4215451039 15451040
MESH:D000686 Amyloidosis Diethylstilbestrol 4.5415469931
MESH:D000799 Angioedema Acetaminophen 3.9410982225
MESH:D000853 Anophthalmos Ethanol 4.8915513904
MESH:D001008 Anxiety Disorders Ethanol 4.0511141031
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6915885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4118445737
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 3.7216206674
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.4317868700
MESH:D001930 Brain Injuries Progesterone 4.3315665606 15380490 15845082
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.3617474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.3615324884 17129689
MESH:D001943 Breast Neoplasms Estradiol 2.3619861407 14630087 17289903 18497071 17261762 16675129 12948864 17018787
MESH:D001943 Breast Neoplasms Genistein 2.3616873071 17200150 16541309
MESH:D001943 Breast Neoplasms Progesterone 2.3615562024 16175315 17614352
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.3911589617
MESH:D002056 Burns Ethanol 4.7216374292
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.5516111702
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 17.123084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 17.1215073043 16217749 11135700 14691202 15553829
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 17.1220514400 19822196 16502159 19519916 18691550 17162532 20727157 17428255 18393292 16830150 19919837 17138121 18665156 18494052 17055752 20101231 18971187 20935162 10737359 20524982 16878318 20512989 18506893 16779866 10672840 17978847 20432363 18978308 16935385 16807293 17761372 18785209 3084413 19539802 19418558 19107877 19052882 19383236 16569478 11831363 17173139 21159647 16681979 19335982 18788625 19394651 16328049 3581430 19701751 19171122 20214788 20084675 18210153 20007298 19208518 16540662 18056438 16698587 16288022
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 17.1216924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 17.1216924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 17.1218788625 15763234 15289165
MESH:D006528 Carcinoma, Hepatocellular Genistein 17.1216924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 17.1220935162 1701930 6705139 17173139 20007298
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.9719014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.1712490120
MESH:D006332 Cardiomegaly Ethanol 3.4619332462
MESH:D002318 Cardiovascular Diseases Genistein 3.3416332659
MESH:D002386 Cataract Acetaminophen 2.6110977129
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 6.8217174075 7505956 21159647 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.8218566989
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.324080065
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.7319052882
MESH:D002779 Cholestasis Ethinyl Estradiol 2.9116919318 17110522 16105132 17333356 11677210 17681005 15861022
MESH:D002971 Cleft Lip Ethanol 3.6115513904
MESH:D002972 Cleft Palate Ethanol 3.1915513904
MESH:D003110 Colonic Neoplasms Genistein 2.2917182828
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.2512609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.8810525206
MESH:D019465 Craniofacial Abnormalities Ethanol 2.8811198716 10194807 19302082 15451039 11873399 15451040 15513904
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.6216002989 12952375
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.1515213294
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.5620387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 4.5616647724
MESH:D003928 Diabetic Nephropathies Estradiol 3.4619279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.5617187935
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.3611421492 16393943 19164858 10663392 12594235 11529661 19085960 18713872 15968718 19923254 17522070 17562736 16227642 14725611 16177239 11461765 14986274 19416960 17906064 11743745 11834606 16781746 12958197 11739529 18071297 15619225 10915739 12540782 12705907 19370779 16109766 2444490 11287661 12392966 16081117 12153990 19739265 16485898 10774834 19420014 14550746
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 6.3619107877
MESH:D056486 Drug-Induced Liver Injury Ethanol 6.3611566570
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1919426721
MESH:D004421 Dystonia Phenobarbital 4.061851702
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.2512538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 9.2517692515
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 12.1716402032
MESH:D004714 Endometrial Hyperplasia Genistein 12.1716402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 12.7216804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 12.7218566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Genistein 12.7211473722
MESH:D004715 Endometriosis Progesterone 3.8216134523
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.183659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.9711558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.9120417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.596401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.327750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.103659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.2116302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.7512903497
MESH:D004938 Esophageal Neoplasms Ethanol 4.7516704527
MESH:D005234 Fatty Liver arsenic trioxide 19.2815073043
MESH:D005234 Fatty Liver Diethylnitrosamine 19.2821071580 20387270
MESH:D005234 Fatty Liver Ethanol 19.2816409862 19236843 18620774
MESH:D005234 Fatty Liver Ethinyl Estradiol 19.2815345470
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.7617920746
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.6916611131 16513791 16534752 15751030 16002989
MESH:D005310 Fetal Alcohol Syndrome Ethanol 5.3815513904 16946407 10194807 15451040
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.3316904648
MESH:D005756 Gastritis Acetaminophen 11.4616983495
MESH:D005756 Gastritis Ethanol 11.4615046732
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 5.0316452187
MESH:D005909 Glioblastoma Genistein 3.2916598420
MESH:D006529 Hepatomegaly Phenobarbital 3.5616109766
MESH:D006558 Herpes Genitalis Estradiol 5.1315709030
MESH:D019584 Hot Flashes Estradiol 3.8517088409
MESH:D006930 Hyperalgesia Acetaminophen 7.9516870215
MESH:D006930 Hyperalgesia Ethanol 7.9518783367
MESH:D006965 Hyperplasia Diethylstilbestrol 4.5114722030 12960047
MESH:D007021 Hypospadias Diethylstilbestrol 11.4916002989
MESH:D007021 Hypospadias Ethinyl Estradiol 11.4916945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.4715869954
MESH:D007246 Infertility Diethylstilbestrol 4.4215036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5217937319
MESH:D007249 Inflammation Diethylnitrosamine 5.2618785209
MESH:D007249 Inflammation Progesterone 5.2615869954
MESH:D007333 Insulin Resistance Estradiol 3.0016393666 16627594
MESH:D007569 Jaw Abnormalities Ethanol 4.4615513904
MESH:D007674 Kidney Diseases Acetaminophen 5.9815629191 12587719
MESH:D007674 Kidney Diseases Estradiol 5.9815618244
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 7.6916762066 15003126 14681315
MESH:D007680 Kidney Neoplasms Estradiol 7.6915610895
MESH:D007859 Learning Disorders Diethylstilbestrol 10.0317184923
MESH:D007859 Learning Disorders Ethanol 10.0315451040
MESH:D007938 Leukemia arsenic trioxide 6.5215070760
MESH:D007938 Leukemia Genistein 6.5217468513 18980019
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.8512560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.3916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.4714633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.8119077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1516467208 20471514 16968895 19850784 17050201
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.2511468182 16330433 17649720 12679006 19642359 19075265 19035177 15748426 16112521 16331271 16823087 12018890 12712474 19225113 9834237 15336539 17107899 15622746 17712046 17869043 15213294 16966277 16891316 11161223 17217047
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.4216882451
MESH:D017880 Limb Deformities, Congenital Ethanol 3.8517676605
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 11.2618522880 19638242 20032147 18407596 18665156
MESH:D008103 Liver Cirrhosis Ethanol 11.2615289165
MESH:D008103 Liver Cirrhosis Phenobarbital 11.2621047994
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 5.1818295389
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 3.6514716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 3.6518166357
MESH:D008106 Liver Cirrhosis, Experimental Genistein 3.6517823541
MESH:D008107 Liver Diseases Acetaminophen 6.5612969438 11587558 19784758 16611625 16610002 19460945 19014921 12587719
MESH:D008107 Liver Diseases Diethylnitrosamine 6.5617034775
MESH:D008107 Liver Diseases Phenobarbital 6.5619363144
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.7217347304 17207112
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2917185352 16871587
MESH:D008113 Liver Neoplasms arsenic trioxide 14.4814682389
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 14.4821295105 19389873
MESH:D008113 Liver Neoplasms Diethylnitrosamine 14.4819833225 20101389 20405173 19426721 19690152 2422723 19996281 20452335 19073162 19254457 20583210 18648771 19256749 21278145 19255062 15175105 21167192 20118626 12112319 18977376 19427195 19499222 9163691 18978307 20434301 19812893 21047994 19294768 19850985 20501860 20492335 18754104 10737359 18644402 16942905 12771043 15885732 19638242 21071580 19551842 2862719 19090486 19642983 20137499
MESH:D008113 Liver Neoplasms Diethylstilbestrol 14.4816712894 15890375
MESH:D008113 Liver Neoplasms Phenobarbital 14.4815975961 19812893 19073162 8742319 21047994 19482888
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 14.4420377131
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 14.4418164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 14.4418282651 18544905 18093689 19009564 18253720 17174075 18164116 16267830 19126423 18775883 19519916 18079962 18308698 2563599 16842330 19539802 17854601 19004024 3124819 9362446 17942915 21159647
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 14.442563599 17172636 6150874 1399818 18308698
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3915213294
MESH:D008175 Lung Neoplasms arsenic trioxide 2.5011798837 19825857
MESH:D008175 Lung Neoplasms Diethylnitrosamine 2.506695378 20970405 20512841 21163286
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.2315166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.5115700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.6116002989
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 10.2216891317 17203775 11408345 11807958
MESH:D008325 Mammary Neoplasms, Experimental Genistein 10.2212929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 10.2211408345 17203775
MESH:D020149 Manganese Poisoning Estradiol 4.5819453300
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6419513568
MESH:D008569 Memory Disorders Ethanol 4.2518411066 15451040
MESH:D009101 Multiple Myeloma arsenic trioxide 3.1419417148 19549372 15949261 14977855 11468182
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.7718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.1716105982 16882451
MESH:D009203 Myocardial Infarction Genistein 2.8817141266
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.6516810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 8.6517141266
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.5617484760
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.0216624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.593581430 9029167
MESH:D009369 Neoplasms Diethylstilbestrol 2.7915313581
MESH:D009389 Neovascularization, Pathologic Estradiol 3.8117289903
MESH:D009421 Nervous System Malformations Diethylstilbestrol 16.8811399458
MESH:D009421 Nervous System Malformations Estradiol 16.8816427766 11399458
MESH:D009421 Nervous System Malformations Genistein 16.8816427766
MESH:D009436 Neural Tube Defects arsenic trioxide 3.1510525206
MESH:D009447 Neuroblastoma Topotecan 3.8715176712
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.3318514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.3320387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.2120387270
MESH:D010018 Osteomalacia Phenobarbital 4.4517016548
MESH:D010024 Osteoporosis Genistein 3.2819401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 4.1416169203
MESH:D010051 Ovarian Neoplasms arsenic trioxide 11.4412452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Estradiol 11.4419401270
MESH:D010051 Ovarian Neoplasms Genistein 11.4419005980
MESH:D010051 Ovarian Neoplasms Progesterone 11.4416525653 17393432
MESH:D010146 Pain Acetaminophen 2.4316870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 12.5115580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 12.5116540662
MESH:D010190 Pancreatic Neoplasms Ethanol 12.5112384795
MESH:D010190 Pancreatic Neoplasms Phenobarbital 12.5116965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7511578682
MESH:D010235 Paraganglioma arsenic trioxide 4.2219927285
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.2714722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.7416977796 15687265
MESH:D011230 Precancerous Conditions Diethylnitrosamine 9.252563599
MESH:D011230 Precancerous Conditions Phenobarbital 9.252563599
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 4.1917184923
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.9420887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0919131511
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.0915046698 17136230 15846301
MESH:D011471 Prostatic Neoplasms Estradiol 2.0916740699
MESH:D011471 Prostatic Neoplasms Genistein 2.0916925846 15256057 15378649
MESH:D011537 Pruritus Ethinyl Estradiol 3.3916919318 15861022
MESH:D019310 Pseudolymphoma Phenobarbital 4.5912752131
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.8718045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.0216646077
MESH:D012640 Seizures Ethanol 6.289754883
MESH:D012640 Seizures Phenobarbital 6.283137016 16876388 11442880 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 4.906407741
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 2.718532709
MESH:D013088 Spermatocele Diethylstilbestrol 12.0416002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 12.0416709447
MESH:D013119 Spinal Cord Injuries Progesterone 4.3616503802 15862959
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.4617007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.4618456281
MESH:D013274 Stomach Neoplasms Ethanol 3.4618456281
MESH:D013276 Stomach Ulcer Ethanol 3.589562338 17918041 9211565 11906479 17189318 16755016
MESH:D013375 Substance Withdrawal Syndrome Ethanol 4.309754883
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2015669648
MESH:D013964 Thyroid Neoplasms arsenic trioxide 12.2319014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 12.237505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 12.231399818
MESH:D013978 Tibial Fractures Estradiol 4.7819048282
MESH:D016171 Torsades de Pointes arsenic trioxide 4.0415213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 5.3311780464 20435036 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 5.3316712894 17306315 16452187
MESH:D014581 Urticaria Acetaminophen 3.0310982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 4.0816175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.2714652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 9.6915809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.6914692618
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.5116002989 16513791
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5914671159 15869587
Pathway ID Pathway Name
KEGG:04910 Insulin signaling pathway
KEGG:04010 MAPK signaling pathway
Pharmacogenomics Knowledge Base Top
Drug Bank Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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