AutismKB 2.0

Annotation Detail for ANK3


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Basic Information Top
Gene Symbol:ANK3 ( ANKYRIN-G,FLJ45464 )
Gene Full Name: ankyrin 3, node of Ranvier (ankyrin G)
Band: 10q21.2
Quick LinksEntrez ID:288; OMIM: 600465; Uniprot ID:ANK3_HUMAN; ENSEMBL ID: ENSG00000151150; HGNC ID: 494
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1848Embryoma
2197Metabolism disease
Desease Name
bipolar disorder
PSYCH
schizophrenia
Desease Name
Bipolar disorder
Schizophrenia
Bipolar disorder and major depressive disorder (combined)
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of ANK3 mRNAdecreases expression 19933214
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in decreased expression of ANK3 mRNAdecreases expression 20406850
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of ANK3 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of ANK3 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ANK3 mRNAaffects expression 16483693
C004984 apocarotenal apocarotenal results in increased expression of ANK3 mRNAincreases expression 17034753
C006632 arsenic trioxide arsenic trioxide results in decreased expression of ANK3 mRNAdecreases expression 15761015
C006632 arsenic trioxide arsenic trioxide results in increased expression of ANK3 mRNAincreases expression 15761015
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of ANK3 mRNAdecreases expression 20106945
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of ANK3 mRNAdecreases expression 20713471
D019207 beta Carotene beta Carotene results in increased expression of ANK3 mRNAincreases expression 17034753
C095105 bexarotene bexarotene results in decreased expression of ANK3 mRNAdecreases expression 16648578
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of ANK3 mRNAdecreases expression 17484886
D016572 Cyclosporine Cyclosporine results in decreased expression of ANK3 mRNAdecreases expression 20106945
C056507 gemcitabine gemcitabine results in increased expression of ANK3 mRNAincreases expression 17039268
D007657 Ketone Bodies Ketone Bodies results in increased expression of ANK3 mRNAincreases expression 16807920
C008493 methylselenic acid methylselenic acid results in decreased expression of ANK3 mRNAdecreases expression 18548127
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ANK3 mRNAaffects binding|decreases expression|increases activity 19710929
D020849 Raloxifene Raloxifene affects the expression of ANK3 mRNAaffects expression 16079270
D012643 Selenium [Selenium co-treated with Vitamin E] results in decreased expression of ANK3 mRNAaffects cotreatment|decreases expression 19244175
C004648 testosterone enanthate testosterone enanthate affects the expression of ANK3 mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of ANK3 mRNAdecreases expression 20055451
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of ANK3 mRNAdecreases expression 19933214
C025643 vinclozolin vinclozolin affects the expression of ANK3 mRNAaffects expression 19015723
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in decreased expression of ANK3 mRNAaffects cotreatment|decreases expression 19244175
D014810 Vitamin E Vitamin E results in decreased expression of ANK3 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7411752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.4518287403
MESH:D055371 Acute Lung Injury pirinixic acid 3.0118653653
MESH:D000230 Adenocarcinoma arsenic trioxide 4.2619825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.2620464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 2.596695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.5416434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.5416835633
MESH:D000419 Albuminuria Raloxifene 4.4917308373 17451421
MESH:D000544 Alzheimer Disease Raloxifene 2.5215800139
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8511748828
MESH:D000799 Angioedema Acetaminophen 3.7410982225
MESH:D001008 Anxiety Disorders vinclozolin 3.5519015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.9619183758
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001714 Bipolar Disorder marker/mechanism 18711365
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 14.6916206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 14.6919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 14.6912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6915746008
MESH:D001930 Brain Injuries Raloxifene 4.3716580743
MESH:D002545 Brain Ischemia beta Carotene 4.9816157235
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.3317474063 20146248
MESH:D001943 Breast Neoplasms bexarotene 2.3316344269 16818667
MESH:D001943 Breast Neoplasms gemcitabine 2.3318382427 17039268
MESH:D001943 Breast Neoplasms Raloxifene 2.3317893378 16837676 17049068 17595753 17261762 16912660 17952589 17440819 15758505 15775269 17242785 15572757
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3320435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.2211589617
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 9.573786805 16097048 10355542 16050911 15721981 16192424 16227642 18705752 15700767 16011737 15673190 16124888
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 9.5716050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7116835633
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 6.4116705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 6.413084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 6.4116217749 11135700 15553829 15073043 14691202
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 6.4118788625
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.1916247446
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7719014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.0212490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.0220419170
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 3.9717572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3118670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Raloxifene 3.3715775269
MESH:D002386 Cataract Acetaminophen 2.5210977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 6.326135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.3212371664
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0716835633
MESH:D002779 Cholestasis Cyclosporine 7.4919486331
MESH:D002779 Cholestasis pirinixic acid 7.4919176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.068697196 15668235 16354765 15340226 12621046
MESH:D003072 Cognition Disorders Raloxifene 4.5115800139
MESH:D003092 Colitis Selenium 3.6717936198
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9614669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.7010525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7010048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.7019769572
MESH:D003456 Cryptorchidism vinclozolin 4.2314966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.9118551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9915213294
MESH:D003865 Depressive Disorder, Major Raloxifene 4.0717474826
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3818249437
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6417107852
MESH:D003928 Diabetic Nephropathies Raloxifene 3.8417308373 17451421 15920148
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 11.6618551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.6619923254 11461765 2444490 12540782 11743745 12705907 16393943 17906064 12594235 12153990 16485898 11421492 15619225 18071297 19164858 11287661 17562736 12958197 19370779 19739265 18713872 16781746 11739529 14725611 16227642 10915739 16177239 19416960 15968718 14550746 16081117 17522070 14986274 10663392 10774834 11529661 19085960 16109766 19420014 11834606 12392966
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 11.664309450 15027814 15968718 10915739 7120509 21278145 17522070 2869522 7440962 10092053 16227642 11566570 3786805 7179309 15998439 19336974 6623471 6884620 16177239 19085960 3732212 9327722
MESH:D056486 Drug-Induced Liver Injury Selenium 11.6615131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.6620420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9919426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6811462148
MESH:C538011 Eales disease Vitamin E 4.609068938
MESH:D004487 Edema pirinixic acid 10.8412083418
MESH:D004487 Edema Raloxifene 10.8415860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.8412711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8016714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 3.8915845917
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.929294722 10568697
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.3412903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.3416530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9311564622
MESH:D005234 Fatty Liver arsenic trioxide 23.5715073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 23.5712631006 61145 12795759 16239168 17595544 19224547 15959796 16045604
MESH:D005234 Fatty Liver Cyclosporine 23.5719224547
MESH:D005234 Fatty Liver pirinixic acid 23.5719236843 20131406
MESH:D005234 Fatty Liver Raloxifene 23.5717473493
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3511858732
MESH:D005355 Fibrosis Carbon Tetrachloride 14.0818705752
MESH:D005355 Fibrosis Cyclosporine 14.0812639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.0820067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1516904648
MESH:D005756 Gastritis Acetaminophen 3.5716983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.8316973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.1916417039
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.118708960
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4910696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.7720471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.7710048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 10.7716080930
MESH:D006331 Heart Diseases Raloxifene 3.4611110106
MESH:D006333 Heart Failure pirinixic acid 6.7320558911
MESH:D006333 Heart Failure Selenium 6.7317162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3115720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2311000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.4919900420 19110552
MESH:D006529 Hepatomegaly pirinixic acid 7.9019176532 18467677 19772884 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.9015340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6616863852 16490937
MESH:D015658 HIV Infections beta Carotene 3.9916960176
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.6417440010
MESH:D019584 Hot Flashes Vitamin E 3.8714716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9416959395 15340226 16354765 18606429 8697196
MESH:D006930 Hyperalgesia Acetaminophen 2.6116870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.4216899240
MESH:D006943 Hyperglycemia pirinixic acid 3.0820558911
MESH:D006973 Hypertension Cyclosporine 8.3410903974
MESH:D006973 Hypertension Raloxifene 8.3417577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.3418670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9815338365
MESH:D007248 Infertility, Male vinclozolin 2.9716467254
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.8012200463 12878042
MESH:D007251 Influenza, Human Selenium 10.6116624496
MESH:D007251 Influenza, Human Vitamin E 10.6116624496
MESH:D007333 Insulin Resistance pirinixic acid 2.5616306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2316580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3415604871
MESH:D007674 Kidney Diseases Acetaminophen 9.6415629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 9.6418776723 10903974 8314463
MESH:D007674 Kidney Diseases Vitamin E 9.6412488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.7816518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 6.9716705839
MESH:D007680 Kidney Neoplasms Cyclosporine 6.9712371664
MESH:D007889 Leiomyoma Raloxifene 4.3916973256
MESH:D007938 Leukemia arsenic trioxide 2.7815070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6912560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.2016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.6619077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1216467208 16968895 20471514 19850784 17050201
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.1416966277 16331271 19075265 15622746 16891316 17869043 17649720 15748426 11161223 15336539 16823087 17217047 16112521 12679006 19225113 12018890 15213294 17712046 11468182 9834237 17107899 16330433 19642359 19035177 12712474
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2416882451
MESH:D007984 Leydig Cell Tumor vinclozolin 4.6216417039
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.7517157831 16221502 17334410 16239168 17174718 16943688 11903743 11408273 21278145
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.8217900296 14716496 17631135 16248980 16027843 18210741 15052691 12666154 13678700 17823541 15123356 18395914 18205269 15931870 15362042 17805973 16097048 18412020 17708605 15338365 18376398 18472332 18429990 16015684 18418968 18251166 18187930 17922224 17761835 14748882 17714472 16638106 15818738 18277467 12586293 17557913 16011737 12632514 16033810 12898905 18279442 15730626 12958196 12546737 18156304 15673190 15876570 16116963 12632512 18395095 12667390 11481614 17525996 18481824 15996030 17481882 17766677 18472094 16192424 18705752 10355542 17976157 17640975 16136751 12445421 15959796 17721639 20821823 18339082 15650968 12741479 12389079 14620537 18166357 15370692 18006644 12649538 18317297 14724832 14716833 15057751 12445418 17869086 14512876 17698563 18263696 17565644 18054572 15925388 12609069 17944888 18420326 15893842
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.8215474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.8212878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.8216169303
MESH:D008107 Liver Diseases Acetaminophen 3.8012969438 12587719 19460945 11587558 19784758 16611625 19014921 16610002
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.8016246199 15720792 16964402 17285989 15830285
MESH:D017093 Liver Failure Carbon Tetrachloride 4.0515123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.0816871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.0816899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 17.447678174
MESH:D008113 Liver Neoplasms arsenic trioxide 17.4414682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 17.4420195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 17.4419294768
MESH:D008113 Liver Neoplasms pirinixic acid 17.4420007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.4416984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 17.946135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 17.9420377131
MESH:D008114 Liver Neoplasms, Experimental beta Carotene 17.9417113696
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 17.9412014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 17.9412151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2615213294
MESH:D008171 Lung Diseases Vitamin E 3.1016863852
MESH:D008175 Lung Neoplasms arsenic trioxide 8.3919825857 11798837
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 8.3920464547 18816296 17053015 20869020 18520028 20064080 6695378 18569708 20135361
MESH:D008175 Lung Neoplasms beta Carotene 8.3916401635
MESH:D008175 Lung Neoplasms bexarotene 8.3917849452
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.3919555203 11884234
MESH:D008175 Lung Neoplasms Vitamin E 8.3911062179
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 5.0411161223
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 6.1015591091 19196723 19196722
MESH:D008325 Mammary Neoplasms, Experimental Selenium 6.1015318939
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4619513568
MESH:D008654 Mesothelioma Selenium 2.7515107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6816801185
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.4515863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.1016381670
MESH:D009101 Multiple Myeloma arsenic trioxide 7.1515949261 11468182 19549372 19417148 14977855
MESH:D009101 Multiple Myeloma Raloxifene 7.1516497877
MESH:D009135 Muscular Diseases pirinixic acid 3.4016239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.0816105982 16882451
MESH:D009203 Myocardial Infarction pirinixic acid 2.1019151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9312213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8616411023
MESH:D009232 Myxoma Raloxifene 5.4516343187
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.757678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.8516624393
MESH:D009369 Neoplasms Benzo(a)pyrene 8.0411141357
MESH:D009369 Neoplasms beta Carotene 8.0417051425
MESH:D009369 Neoplasms pirinixic acid 8.0417405874
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 4.6819196722
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1919348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.1114600291
MESH:D009436 Neural Tube Defects arsenic trioxide 3.0410525206
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.7818514411
MESH:D009765 Obesity pirinixic acid 1.7920558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.3316049721
MESH:D010024 Osteoporosis Raloxifene 3.3317882678 15775268 19059307
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.1217823083 15579764 15758505 17893378
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.3719769630 12452020 16624393
MESH:D010146 Pain Acetaminophen 2.3016870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 5.5515580305
MESH:D010190 Pancreatic Neoplasms gemcitabine 5.5511504793 16929163 17440100 18383843 18992248
MESH:D010235 Paraganglioma arsenic trioxide 4.0619927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1412520081
MESH:D010954 Plasmacytoma Selenium 4.7815087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4518163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.1312371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.1311896295 11118676 11222880 11399792
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 9.1318042343 18220299 19015723
MESH:D011469 Prostatic Diseases vinclozolin 4.8318220299
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8819131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.8817292933
MESH:D011471 Prostatic Neoplasms methylselenic acid 1.8816205645
MESH:D011471 Prostatic Neoplasms Raloxifene 1.8816536755 15731164 16220300
MESH:D011471 Prostatic Neoplasms Vitamin E 1.8815084515
MESH:D011472 Prostatitis vinclozolin 4.8318629315
MESH:D011565 Psoriasis Cyclosporine 2.1916882103
MESH:D011693 Purpura Raloxifene 5.4515770314
MESH:D015427 Reperfusion Injury pirinixic acid 2.3319058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7318990726
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.8516646077
MESH:D012640 Seizures 2,6-dinitrotoluene 2.4618551238
MESH:D012871 Skin Diseases Vitamin E 2.4118709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.3019755658 10029692
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.3016192470
MESH:D013272 Stomach Diseases beta Carotene 4.9817638125
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.3417007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.342093021 20155912
MESH:D013276 Stomach Ulcer beta Carotene 4.1612500499
MESH:D020521 Stroke Raloxifene 8.4216837676
MESH:D020521 Stroke Vitamin E 8.4216517955
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8012697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.0019014326
MESH:D013978 Tibial Fractures Raloxifene 5.1019048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.8515213294
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 11.5916049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 11.5920435036 12973940 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 11.5917053015
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 11.5917572228
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.2110091137
MESH:D014581 Urticaria Acetaminophen 2.8710982225
MESH:D014605 Uveitis Cyclosporine 3.881336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4912125929
MESH:D054556 Venous Thromboembolism Raloxifene 5.1016837676
MESH:D014846 Vulvar Neoplasms Raloxifene 5.4516343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1415886252
MESH:D014985 Xerophthalmia Cyclosporine 4.3417120751
Pathway ID Pathway Name
REACT:18266 Axon guidance
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA24800
    • No data
    Releated disease ID Related disease Name
    PA447199Bipolar Disorder
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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