AutismKB 2.0

Annotation Detail for GRB14


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Basic Information Top
Gene Symbol:GRB14 ( - )
Gene Full Name: growth factor receptor-bound protein 14
Band: 2q24.3
Quick LinksEntrez ID:2888; OMIM: 601524; Uniprot ID:GRB14_HUMAN; ENSEMBL ID: ENSG00000115290; HGNC ID: 4565
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Hemostasis
Pathway IDPathway Name
200012Insulin Pathway
200066Angiopoietin receptor Tie2-mediated signaling
Pathway IDPathway Name
P00005Angiogenesis
Pathway IDPathway Name
500306Tie2 Signaling
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of GRB14 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GRB14 mRNAaffects expression 16483693
C015001 arsenite arsenite results in decreased expression of GRB14 mRNAdecreases expression 18929588
C015001 arsenite TRP53 protein affects the reaction [arsenite results in decreased expression of GRB14 mRNA]affects reaction|decreases expression 18929588
C027561 butylbenzyl phthalate butylbenzyl phthalate results in increased expression of GRB14 mRNAincreases expression 15728792
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of GRB14 mRNAaffects expression 17484886
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of GRB14 mRNAaffects cotreatment|affects expression 17602206
D016572 Cyclosporine Cyclosporine results in decreased expression of GRB14 mRNAdecreases expression 20106945
D003993 Dibutyl Phthalate Dibutyl Phthalate results in increased expression of GRB14 mRNAincreases expression 15728792
D003993 Dibutyl Phthalate Dibutyl Phthalate results in increased expression of GRB14 proteinincreases expression 15728792
D004041 Dietary Fats Dietary Fats results in increased expression of GRB14 mRNAincreases expression 18042831
D004051 Diethylhexyl Phthalate Diethylhexyl Phthalate results in increased expression of GRB14 mRNAincreases expression 15728792
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of GRB14 mRNAaffects cotreatment|affects expression 17602206
C034171 di-n-pentyl phthalate di-n-pentyl phthalate results in increased expression of GRB14 mRNAincreases expression 15728792
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of GRB14 mRNAaffects cotreatment|increases expression 19619570
D004958 Estradiol Estradiol results in decreased expression of GRB14 mRNAdecreases expression 19619570
20106945
16202921
D000431 Ethanol [Fish Oils co-treated with Ethanol] results in increased expression of GRB14 mRNAaffects cotreatment|increases expression 17347304
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of GRB14 mRNAdecreases expression 12655037
15834898
D005395 Fish Oils [Fish Oils co-treated with Ethanol] results in increased expression of GRB14 mRNAaffects cotreatment|increases expression 17347304
D006918 Hydroxyurea Hydroxyurea results in increased mutagenesis of GRB14 geneincreases mutagenesis 16868089
D008701 Methapyrilene Methapyrilene results in decreased expression of GRB14 mRNAdecreases expression 16393664
D008770 Methylnitrosourea Methylnitrosourea results in increased mutagenesis of GRB14 geneincreases mutagenesis 16868089
C041786 palm oil palm oil results in increased expression of GRB14 mRNAincreases expression 18042831
D011794 Quercetin Quercetin results in decreased expression of GRB14 mRNAdecreases expression 15309432
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of GRB14 mRNAaffects cotreatment|increases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of GRB14 mRNAdecreases expression 20106945
19619570
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Diethylhexyl Phthalate 13.656734493
MESH:D000014 Abnormalities, Drug-Induced Ethanol 13.6517676605 18926900
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 13.6511752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 10.0318287403
MESH:D000138 Acidosis Ethanol 10.0311192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8117505938
MESH:D000230 Adenocarcinoma Estradiol 6.9611473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.9614692618
MESH:D000230 Adenocarcinoma Methylnitrosourea 6.9615688392 15113128
MESH:D000236 Adenoma Diethylnitrosamine 2.7810737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 9.6218056438 19061943 16434500 17620307 17162532 19052882
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.6216835633
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 5.1915451039 15451040
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8311748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.1217084956
MESH:D000853 Anophthalmos Ethanol 4.6915513904
MESH:D001008 Anxiety Disorders Ethanol 3.9011141031
MESH:D001161 Arteriosclerosis Dietary Fats 9.4715238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.4711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5815885639
MESH:D001260 Ataxia Telangiectasia Quercetin 4.8515336622
MESH:D001327 Autoimmune Diseases Quercetin 4.2819761891
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 2.9212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6815746008
MESH:D001943 Breast Neoplasms Dietary Fats 2.9020435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.9017474063
MESH:D001943 Breast Neoplasms Estradiol 2.9019861407 12948864 17261762 17018787 18497071 16675129 17289903 14630087
MESH:D001943 Breast Neoplasms Methylnitrosourea 2.9016253758 14633655 11306469
MESH:D001943 Breast Neoplasms Quercetin 2.9018628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.9020435547
MESH:D002056 Burns Ethanol 4.5216374292
MESH:D002105 Cadmium Poisoning Quercetin 5.4216962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3316111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.653786805 15673190 16097048 15700767 16050911 15721981 10355542 16227642 18705752 16011737 16192424 16124888
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6916835633
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 11.1212619106 21507988 12907637
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 11.1218788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.1216502159 17173139 20514400 17138121 18788625 19171122 19919837 17761372 20727157 16288022 16878318 17428255 19052882 20935162 3084413 17978847 16569478 18971187 16328049 19383236 18506893 17162532 18393292 20512989 19539802 11831363 17055752 16807293 18210153 18691550 20214788 18056438 10672840 18978308 19701751 3581430 16935385 16681979 18665156 20432363 19519916 19394651 16830150 19822196 10737359 16540662 19335982 19208518 21159647 20524982 20101231 20007298 19418558 20084675 18494052 19107877 16779866 16698587 18785209
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.1216924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 11.1218788625 15763234 15289165
MESH:D006528 Carcinoma, Hepatocellular Quercetin 11.1212508355 19519916
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.8217234771
MESH:D006332 Cardiomegaly Ethanol 11.0419332462
MESH:D006332 Cardiomegaly Quercetin 11.0419794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 11.0418670907 18850075 16120746
MESH:D002386 Cataract Methylnitrosourea 3.9112484553
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 15.3212371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 15.3217174075 2727394 7505956 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 15.3218566989
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 15.327505956 2727394
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.9519052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.9516835633
MESH:D002779 Cholestasis Cyclosporine 7.4519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.4517110522 17333356 16919318 11677210 16105132 15861022 17681005
MESH:D002971 Cleft Lip Ethanol 3.5215513904
MESH:D002972 Cleft Palate Ethanol 5.7715513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.7716354765 8697196 12621046 15340226 15668235
MESH:D003110 Colonic Neoplasms arsenite 3.9515037631
MESH:D003110 Colonic Neoplasms Quercetin 3.9511134977 16640504 19440933 17148506 15741050 17191121 19056647
MESH:D015179 Colorectal Neoplasms Quercetin 2.1818852136 18095365
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9514669216 17141729
MESH:D019465 Craniofacial Abnormalities Ethanol 2.5915451040 19302082 10194807 15451039 15513904 11198716 11873399
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.5915322242 10048152 20055451
MESH:D003456 Cryptorchidism Dibutyl Phthalate 5.3216037377
MESH:D003876 Dermatitis, Atopic Diethylhexyl Phthalate 3.9916882537
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.6219496084
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.1120387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.1117107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.3019279558
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 8.6710092053 10915739 15998439 16227642 3732212 16177239 3786805 17522070 11566570 2869522 7179309 19085960 19336974 15968718 7120509 21278145 6623471 4309450 6884620 9327722 15027814 7440962
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 8.6719107877
MESH:D056486 Drug-Induced Liver Injury Ethanol 8.6711566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 8.6720420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6611462148
MESH:D050171 Dyslipidemias Dietary Fats 3.3618367378
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.2612711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7718230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.0612538720
MESH:D016889 Endometrial Neoplasms Estradiol 2.9011473722 18566989 19148513
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.9110568697 9294722
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9916302075
MESH:D004938 Esophageal Neoplasms Ethanol 2.7216704527
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9111564622
MESH:D005234 Fatty Liver arsenite 41.3418296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 41.3412631006 16239168 12795759 19224547 15959796 17595544 61145 16045604
MESH:D005234 Fatty Liver Cyclosporine 41.3419224547
MESH:D005234 Fatty Liver Dietary Fats 41.3417967931 18296743 19004024 19551842
MESH:D005234 Fatty Liver Diethylnitrosamine 41.3420387270 21071580
MESH:D005234 Fatty Liver Ethanol 41.3418620774 16409862 19236843
MESH:D005234 Fatty Liver Ethinyl Estradiol 41.3415345470
MESH:D005234 Fatty Liver Fish Oils 41.3418620774
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.5417920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 5.1716946407 10194807 15513904 15451040
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3311858732
MESH:D005354 Fibrosarcoma Methylnitrosourea 5.1011555667
MESH:D005355 Fibrosis arsenite 32.8418296743
MESH:D005355 Fibrosis Carbon Tetrachloride 32.8418705752
MESH:D005355 Fibrosis Cyclosporine 32.8412639820 12168785
MESH:D005355 Fibrosis Dietary Fats 32.8418296743
MESH:D005355 Fibrosis Quercetin 32.8419474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 32.8420067830
MESH:D005756 Gastritis Ethanol 4.5615046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.098708960
MESH:D005909 Glioblastoma Quercetin 3.3119804834
MESH:D005910 Glioma Methylnitrosourea 6.279825942
MESH:D005910 Glioma Quercetin 6.2717643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4710696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2611294989 10048152
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2111000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.4719110552 19900420
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.7612621046 15340226 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.9015709030
MESH:D019584 Hot Flashes Estradiol 3.6217088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.928697196 16959395 18606429 16354765 15340226
MESH:D006930 Hyperalgesia Ethanol 3.6118783367
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.4016899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.4721332399
MESH:D006943 Hyperglycemia Quercetin 3.9218262572 11834736
MESH:D006949 Hyperlipidemias Dietary Fats 9.1421332399
MESH:D006949 Hyperlipidemias Fish Oils 9.1415752949
MESH:D006968 Hypersensitivity, Delayed Fish Oils 5.3811484837
MESH:D006973 Hypertension Cyclosporine 8.2910903974
MESH:D006973 Hypertension Quercetin 8.2918356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.2918850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9615338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6816945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.6517937319
MESH:D007248 Infertility, Male Methylnitrosourea 6.657193160
MESH:D007249 Inflammation Dietary Fats 7.8820412841
MESH:D007249 Inflammation Diethylnitrosamine 7.8818785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.8812878042 12200463
MESH:D007251 Influenza, Human Quercetin 4.3816624496
MESH:D007333 Insulin Resistance Dietary Fats 7.0911836018 18457598
MESH:D007333 Insulin Resistance Estradiol 7.0916627594 16393666
MESH:D007569 Jaw Abnormalities Ethanol 9.7215513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.7216580747
MESH:D007627 Keloid Quercetin 4.8217086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3115604871
MESH:D007674 Kidney Diseases Cyclosporine 9.668314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 9.6615618244
MESH:D007674 Kidney Diseases Quercetin 9.6616962696
MESH:D007680 Kidney Neoplasms Cyclosporine 6.9212371664
MESH:D007680 Kidney Neoplasms Estradiol 6.9215610895
MESH:D007859 Learning Disorders Ethanol 4.0815451040
MESH:D007938 Leukemia Quercetin 3.0917468513
MESH:D007951 Leukemia, Myeloid Hydroxyurea 4.8916532439
MESH:D017880 Limb Deformities, Congenital Ethanol 8.3317676605
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 8.3315526292
MESH:D008103 Liver Cirrhosis arsenite 19.9918296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 19.9917174718 11408273 17334410 16943688 11903743 16239168 21278145 17157831 16221502
MESH:D008103 Liver Cirrhosis Dietary Fats 19.9918296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 19.9919638242 18407596 20032147 18522880 18665156
MESH:D008103 Liver Cirrhosis Ethanol 19.9915289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.9718295389
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 6.5715673190 12958196 18472332 16011737 17714472 12667390 16248980 13678700 14716496 18705752 18210741 18418968 17761835 18279442 17823541 15959796 12666154 18481824 15931870 17900296 18395914 15057751 17805973 18156304 15338365 15893842 15818738 17631135 16015684 14724832 18376398 17525996 17922224 17944888 14748882 15123356 16638106 17766677 17557913 12632512 18277467 16033810 18251166 15650968 12898905 14716833 12632514 15876570 15730626 17640975 18412020 12609069 12546737 17565644 18472094 15362042 14620537 18166357 12649538 12445421 12389079 18317297 15370692 16192424 17481882 15052691 12445418 16116963 17869086 18429990 11481614 10355542 14512876 16097048 16136751 17976157 20821823 18395095 17698563 18205269 15925388 12741479 18054572 18420326 18006644 16027843 18263696 12586293 18187930 18339082 17721639 17708605 15996030
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.5714716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 6.5718166357
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 6.5712741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.5712878042
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.9616964402 15720792 16246199 17285989 15830285
MESH:D008107 Liver Diseases Diethylnitrosamine 3.9617034775
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.5217207112 17347304
MESH:D017093 Liver Failure Carbon Tetrachloride 4.0315123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.5716899240 14706259
MESH:D008113 Liver Neoplasms Aflatoxin B1 25.1315890375 18177683 2125692 9163691
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 25.1319294768
MESH:D008113 Liver Neoplasms Clofibric Acid 25.1317602206
MESH:D008113 Liver Neoplasms Diethylhexyl Phthalate 25.1311940454
MESH:D008113 Liver Neoplasms Diethylnitrosamine 25.139163691 15885732 12771043 19427195 19256749 20501860 19812893 20583210 20137499 19073162 12112319 20118626 20452335 2422723 18644402 10737359 19638242 19551842 18754104 20434301 18977376 21047994 20101389 21167192 19690152 19254457 18648771 15175105 19426721 16942905 21278145 19090486 19294768 19642983 19499222 2862719 20492335 20405173 18978307 19833225 19850985 21071580 19996281 19255062
MESH:D008113 Liver Neoplasms Methapyrilene 25.1315890375
MESH:D008113 Liver Neoplasms Quercetin 25.1318980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 25.1316984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 17.788603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 17.7815583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 17.7817174075 18079962 18282651 18544905 2563599 18775883 17942915 16267830 9362446 19539802 19004024 19009564 21159647 19126423 18308698 18093689 3124819 18164116 19519916 16842330 18253720 17854601
MESH:D008114 Liver Neoplasms, Experimental Quercetin 17.7819519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 17.7812151625
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 5.3316080182
MESH:D008175 Lung Neoplasms Aflatoxin B1 8.3614755239
MESH:D008175 Lung Neoplasms arsenite 8.3616809336
MESH:D008175 Lung Neoplasms Diethylnitrosamine 8.3620512841 20970405 6695378 21163286
MESH:D008175 Lung Neoplasms Methylnitrosourea 8.3618062963
MESH:D008175 Lung Neoplasms Quercetin 8.3616280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.3619555203 11884234
MESH:D008223 Lymphoma Methylnitrosourea 3.9211418001 16257854
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 4.6514633661
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 6.0411408345 11807958 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 6.0410767621 16944150 15113128 16051031 15313902 12931682 11807958 17131329 11751437 10838139 16619500 14633655 14999141 19196723 17020996 16827153 15688392
MESH:D020149 Manganese Poisoning Estradiol 4.3519453300
MESH:D008569 Memory Disorders Ethanol 4.0615451040 18411066
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6616801185
MESH:D009203 Myocardial Infarction Quercetin 2.9419595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.2316810080
MESH:D015428 Myocardial Reperfusion Injury Quercetin 8.2319207477
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.523581430 9029167
MESH:D009369 Neoplasms Methylnitrosourea 5.3415533788
MESH:D009369 Neoplasms Quercetin 5.3415185748
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 4.3412696579
MESH:D009389 Neovascularization, Pathologic arsenite 9.7115738583
MESH:D009389 Neovascularization, Pathologic Estradiol 9.7117289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1719348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 9.0416427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.0414600291
MESH:D009442 Neurilemmoma Methylnitrosourea 5.3511555667
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.2320387270
MESH:D020078 Neurogenic Inflammation Quercetin 4.2417929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9920387270
MESH:D009765 Obesity Dietary Fats 2.2611836018 17217161 20132043 21332399 18457598 18674790 19632207 20518802 16723640
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.0919495926
MESH:D010051 Ovarian Neoplasms Estradiol 4.8119401270
MESH:D010051 Ovarian Neoplasms Quercetin 4.8119005980
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 12.0316540662
MESH:D010190 Pancreatic Neoplasms Ethanol 12.0312384795
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 12.0316965848
MESH:D010190 Pancreatic Neoplasms Quercetin 12.0316965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5611578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4318163543
MESH:D011230 Precancerous Conditions Cyclosporine 14.6712371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 14.672563599
MESH:D011230 Precancerous Conditions Quercetin 14.6719056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0611896295 11118676 11222880 11399792
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.7620887781
MESH:D011471 Prostatic Neoplasms Estradiol 2.7516740699
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 2.7512376480 15682402
MESH:D011471 Prostatic Neoplasms Quercetin 2.7517292933 14715546
MESH:D011537 Pruritus Ethinyl Estradiol 3.1815861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.1816882103
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7118990726
MESH:D012162 Retinal Degeneration Methylnitrosourea 4.3118172121 18155124
MESH:D012175 Retinoblastoma Methylnitrosourea 5.3511555667
MESH:D012554 Schistosomiasis japonica Quercetin 5.4216862918
MESH:D012640 Seizures Ethanol 3.089754883
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 1.9816192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8116709447
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.4818456281
MESH:D013274 Stomach Neoplasms Ethanol 3.4818456281
MESH:D013274 Stomach Neoplasms Methylnitrosourea 3.4816257854 18593901 15930296
MESH:D013276 Stomach Ulcer Ethanol 3.419211565 17918041 17189318 11906479 9562338 16755016
MESH:D013375 Substance Withdrawal Syndrome Ethanol 4.149754883
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0415669648
MESH:D013953 Thymus Neoplasms Methylnitrosourea 5.1011418001
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7712697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 7.177505956
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 7.173078959 7505956
MESH:D013978 Tibial Fractures Estradiol 4.5619048282
MESH:D001749 Urinary Bladder Neoplasms Quercetin 2.7616720314
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1714692618
MESH:D014605 Uveitis Cyclosporine 3.851336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4214671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1215886252
MESH:D015430 Weight Gain Dietary Fats 3.6216723640
MESH:D014985 Xerophthalmia Cyclosporine 4.3117120751
Pathway ID Pathway Name
REACT:604 Hemostasis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28961
    • No data
    No data
    Releated drug ID Related drug Name
    PA448976choline
    PA448478l-arginine
    PA450635nitric oxide
    PA450626nicotine
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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