AutismKB 2.0

Annotation Detail for GRIA1


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Basic Information Top
Gene Symbol:GRIA1 ( GLUH1,GLUR1,GLURA,GluA1,HBGR1,MGC133252 )
Gene Full Name: glutamate receptor, ionotropic, AMPA 1
Band: 5q33.2
Quick LinksEntrez ID:2890; OMIM: 138248; Uniprot ID:GRIA1_HUMAN; ENSEMBL ID: ENSG00000155511; HGNC ID: 4571
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04720Long-term potentiation
hsa04080Neuroactive ligand-receptor interaction
hsa04730Long-term depression
hsa05014Amyotrophic lateral sclerosis (ALS)
Pathway IDPathway Name
Synaptic Transmission
Pathway IDPathway Name
200041EPHB forward signaling
Pathway IDPathway Name
P00039Metabotropic glutamate receptor group III pathway
P00037Ionotropic glutamate receptor pathway
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
Anthropometric traits
Citalopram/adverse effects*
REPRODUCTION
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C101670 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Kainic Acid results in decreased expression of GRIA1 protein]decreases expression|decreases reaction 17585341
C018855 2-tert-butylhydroquinone 2-tert-butylhydroquinone results in increased expression of GRIA1 mRNAincreases expression 16014739
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GRIA1 mRNAaffects expression 16483693
C025657 arsenic acid arsenic acid analog results in decreased expression of GRIA1 mRNAdecreases expression 19761793
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GRIA1 mRNAaffects cotreatment|increases expression 18164116
D020185 Benzoic Acids Benzoic Acids analog binds to and results in decreased activity of GRIA1 proteinaffects binding|decreases activity 14667236
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of GRIA1 mRNAaffects expression 12734012
D004390 Chlorpyrifos Chlorpyrifos results in increased expression of GRIA1 mRNAincreases expression 19440498
D003024 Clozapine Clozapine results in decreased expression of GRIA1 mRNAdecreases expression 17141476
D003976 Diazinon Diazinon results in decreased expression of GRIA1 mRNAdecreases expression 17452286
D003976 Diazinon Diazinon results in increased expression of GRIA1 mRNAincreases expression 19440498
D004026 Dieldrin Dieldrin results in increased expression of GRIA1 mRNAincreases expression 19440498
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GRIA1 mRNAaffects cotreatment|increases expression 18164116
D005419 Flavonoids Flavonoids results in decreased expression of GRIA1 mRNAdecreases expression 18035473
D006220 Haloperidol Haloperidol results in decreased expression of GRIA1 mRNAdecreases expression 15860345
D007608 Kainic Acid 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Kainic Acid results in decreased expression of GRIA1 protein]decreases expression|decreases reaction 17585341
D007608 Kainic Acid Kainic Acid binds to and results in increased activity of GRIA1 proteinaffects binding|increases activity 11812690
D007608 Kainic Acid Kainic Acid results in decreased expression of GRIA1 proteindecreases expression 17585341
D007608 Kainic Acid Urethane inhibits the reaction [Kainic Acid binds to and results in increased activity of GRIA1 protein]affects binding|decreases reaction|increases activity 11812690
D015735 Mifepristone Mifepristone results in decreased expression of GRIA1 mRNAdecreases expression 17584828
D008911 Minocycline Minocycline inhibits the reaction [Poly C results in increased expression of GRIA1 mRNA]decreases reaction|increases expression 19660546
D009020 Morphine Morphine results in decreased expression of GRIA1 mRNAdecreases expression 15183518
D009020 Morphine Morphine results in increased expression of GRIA1 mRNAincreases expression 15183518
D009151 Mustard Gas Mustard Gas results in decreased expression of GRIA1 mRNAdecreases expression 15674843
D009532 Nickel Nickel results in increased expression of GRIA1 mRNAincreases expression 19440498
D010862 Pilocarpine Pilocarpine results in increased expression of GRIA1 proteinincreases expression 15857427
D011066 Poly C Minocycline inhibits the reaction [Poly C results in increased expression of GRIA1 mRNA]decreases reaction|increases expression 19660546
D011066 Poly C Poly C results in increased expression of GRIA1 mRNAincreases expression 19660546
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of GRIA1 mRNAdecreases expression 16839606
D014520 Urethane Urethane inhibits the reaction [Kainic Acid binds to and results in increased activity of GRIA1 protein]affects binding|decreases reaction|increases activity 11812690
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.6815322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.3918287403
MESH:D055371 Acute Lung Injury Nickel 4.4216166738
MESH:D000230 Adenocarcinoma Urethane 3.2818316556
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Urethane 5.5415814487
MESH:D000236 Adenoma beta-Naphthoflavone 10.8219389873
MESH:D000236 Adenoma Diethylnitrosamine 10.8210737359 6695378
MESH:D000236 Adenoma Urethane 10.8210822126 10530776 6695378 11497255 16926031 17195641 17093202
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 9.4819061943 16434500 17620307 18056438 19052882 17162532
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.4816835633
MESH:D000380 Agranulocytosis Clozapine 4.8812649775 16160616 14617031
MESH:D000382 Agricultural Workers' Diseases Chlorpyrifos 8.6011874814 16611668 17119214
MESH:D000382 Agricultural Workers' Diseases Diazinon 8.6016487989
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8011748828
MESH:D001172 Arthritis, Rheumatoid Minocycline 4.1814528503
MESH:D001249 Asthma Mustard Gas 2.6610378619
MESH:D001321 Autistic Disorder marker/mechanism 11706102
MESH:D001321 Autistic Disorder Haloperidol 2.7518080171 19368416
MESH:D001768 Blister Mustard Gas 4.9919167455
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 2.8912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6515746008
MESH:D002545 Brain Ischemia Morphine 4.9719211983
MESH:D001943 Breast Neoplasms Dieldrin 2.0115770527 11859874
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.0117474063
MESH:D001943 Breast Neoplasms Nickel 2.0115986119
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.0120435547
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.9915286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.8017687719 10378619
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.6115721981 16011737 16227642 16097048 15700767 16050911 16124888 18705752 15673190 16192424 10355542 3786805
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6616835633
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 2.9318788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 2.9316807293 19701751 19335982 19052882 16681979 16935385 17162532 16878318 19418558 16569478 18691550 3084413 20524982 18506893 16698587 17055752 16779866 20214788 18785209 19171122 18971187 17138121 18665156 10672840 19394651 19539802 20007298 17978847 21159647 18393292 19519916 18210153 20101231 16288022 20432363 17173139 18056438 19919837 18978308 19208518 20512989 18788625 17761372 16830150 20935162 20514400 11831363 16540662 3581430 16328049 19822196 20727157 20084675 16502159 18494052 17428255 19107877 10737359 19383236
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2718850075 16120746 18670907
MESH:D002375 Catalepsy Haloperidol 4.741977408 15215559
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 2.7417174075 2727394 7505956 21159647
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.8419052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.8416835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.9316354765 15340226 15668235 8697196 12621046
MESH:D002972 Cleft Palate Urethane 5.9312810352
MESH:D003072 Cognition Disorders Clozapine 4.7917123785
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9117141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2520055451 10048152 15322242
MESH:D016757 Death, Sudden, Cardiac Haloperidol 4.6820210726
MESH:D003704 Dementia Haloperidol 4.4211575062
MESH:D017449 Dermatitis, Allergic Contact Nickel 3.7917244072 17100760 19470301
MESH:D003877 Dermatitis, Contact Nickel 4.472952479
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 6.9216402076
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.9220387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.9217107852
MESH:D003967 Diarrhea Morphine 4.362540324
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.3815331141
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 5.897120509 6884620 19336974 10092053 3732212 15998439 3786805 6623471 4309450 11566570 7440962 15027814 17522070 7179309 9327722 2869522 10915739 21278145 16227642 16177239 15968718 19085960
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 5.8919107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 5.8920420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6311462148
MESH:D050171 Dyslipidemias Clozapine 4.0616402076
MESH:D004417 Dyspnea Diazinon 4.6316487989
MESH:D004487 Edema Mustard Gas 6.3311428647 9260866 11428631 11402378
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.3312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7315322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Minocycline 5.3911835378
MESH:D004715 Endometriosis Mifepristone 8.6516134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.6510568697 9294722
MESH:D004827 Epilepsy Pilocarpine 4.5711162239 19439326 19700373
MESH:D004890 Erythema Mustard Gas 4.999357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9416302075
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8911564622
MESH:D005234 Fatty Liver arsenic acid 12.5018296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 12.5061145 12631006 19224547 12795759 16239168 15959796 17595544 16045604
MESH:D005234 Fatty Liver Diethylnitrosamine 12.5021071580 20387270
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2911858732
MESH:D005355 Fibrosis arsenic acid 14.0218296743
MESH:D005355 Fibrosis Carbon Tetrachloride 14.0218705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.0220067830
MESH:D005600 Fragile X Syndrome Minocycline 6.5818835858
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4210696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2410048152 11294989
MESH:D006331 Heart Diseases Urethane 4.1216046796
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1811000095
MESH:D006505 Hepatitis Carbon Tetrachloride 9.0619900420 19110552
MESH:D006505 Hepatitis Diazinon 9.0616487989
MESH:D006521 Hepatitis, Chronic Minocycline 5.9714986274
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.7215340226 12621046 16120746
MESH:D015658 HIV Infections Nickel 3.7317263646
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8718606429 15340226 16959395 8697196 16354765
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.3616899240
MESH:D006948 Hyperkinesis Clozapine 4.7416046005
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8418850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9215338365
MESH:D007022 Hypotension marker/mechanism 18639534
MESH:D007247 Infertility, Female Dieldrin 4.7810630421
MESH:D007248 Infertility, Male Diazinon 3.7116466525 12948887
MESH:D007249 Inflammation Diethylnitrosamine 14.9418785209
MESH:D007249 Inflammation Flavonoids 14.9417296493
MESH:D007249 Inflammation Mustard Gas 14.948975870 11428620 11402378 17524151 11428647 9260866 9357497 11428631 16001271
MESH:D007249 Inflammation Nickel 14.9416166738
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 14.9412878042 12200463
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1816580747
MESH:D008064 Lipidoses Clozapine 3.8417567588
MESH:D008103 Liver Cirrhosis arsenic acid 10.7218296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.7217174718 16943688 16239168 11408273 21278145 16221502 11903743 17334410 17157831
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.7220032147 18407596 18665156 19638242 18522880
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 2.2316248980 18263696 12649538 14512876 14620537 17631135 18395914 18205269 15931870 15362042 17708605 20821823 12445418 12958196 18412020 15959796 15338365 17525996 17805973 17944888 16638106 15057751 17922224 18418968 16015684 17976157 12632514 14724832 18006644 15893842 17698563 17900296 17481882 14716833 17761835 15876570 18472332 16011737 18054572 11481614 17869086 15052691 15730626 18420326 16136751 16192424 14748882 15370692 12389079 16027843 15673190 12586293 18472094 12609069 15925388 17721639 18277467 18481824 18210741 16097048 18251166 18339082 15818738 13678700 17714472 18395095 18376398 16116963 12898905 17640975 12546737 15123356 17557913 14716496 12741479 18156304 10355542 18705752 18166357 17766677 12666154 15996030 18279442 18429990 16033810 17823541 18317297 15650968 12667390 12632512 17565644 12445421 18187930
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.2312878042
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.4016246199 15720792 16964402 17285989 15830285
MESH:D008107 Liver Diseases Chlorpyrifos 6.4015991261
MESH:D008107 Liver Diseases Diethylnitrosamine 6.4017034775
MESH:D017093 Liver Failure Carbon Tetrachloride 3.9915123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.5416899240 14706259
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 17.1519389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 17.1519294768
MESH:D008113 Liver Neoplasms Dieldrin 17.158742319 9539021
MESH:D008113 Liver Neoplasms Diethylnitrosamine 17.152422723 18754104 16942905 18644402 19090486 19254457 20434301 19499222 19812893 15175105 20583210 19638242 19256749 20452335 9163691 21278145 19427195 19426721 19073162 18648771 2862719 19690152 19850985 12112319 20492335 18977376 19642983 20101389 19551842 12771043 15885732 20137499 18978307 19255062 20118626 19996281 21071580 19294768 10737359 21047994 20501860 21167192 20405173 19833225
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.1516984957
MESH:D008113 Liver Neoplasms Urethane 17.1516391232 17559639 17093202
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 13.2518164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 13.2512014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.2519126423 16267830 2563599 19539802 3124819 18079962 19004024 19009564 21159647 18775883 18282651 19519916 17942915 16842330 18164116 17174075 18253720 18093689 18544905 9362446 18308698 17854601
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.2512151625
MESH:D008171 Lung Diseases Mustard Gas 3.3418161513 18702808
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.7321163286 20970405 6695378 20512841
MESH:D008175 Lung Neoplasms Mustard Gas 4.733148597 8781369
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.7311884234 19555203
MESH:D008175 Lung Neoplasms Urethane 4.7315166089 17195641 16289808 16788158 12957351 7750092 11246140 10530776 11893704 11992545 16391232 17093202 6695378 14587096 12466968 11497255 12765245 15136453 15902970 11307925 10997738 16007126 11544531 16337739 11807781 12117781 16204055 11062179 10822126 11552296 16926031 10779650 11323394 11074608 17255336
MESH:D001523 Mental Disorders Clozapine 7.7916856516
MESH:D001523 Mental Disorders Haloperidol 7.7916856516
MESH:D024821 Metabolic Syndrome X Clozapine 4.2719142101
MESH:D020529 Multiple Sclerosis, Relapsing-Remitting Minocycline 6.6011835378
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8812213967
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.503581430 9029167
MESH:D009369 Neoplasms Dieldrin 5.608820588
MESH:D009369 Neoplasms Urethane 5.6015625555
MESH:D009374 Neoplasms, Experimental Urethane 4.5115582191
MESH:D009395 Nephritis, Interstitial Minocycline 5.75435818 444868
MESH:D009421 Nervous System Malformations Pilocarpine 9.6215987249
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.6214600291
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.2020387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9420387270
MESH:D020258 Neurotoxicity Syndromes Chlorpyrifos 4.0515081274
MESH:D009503 Neutropenia Mustard Gas 3.817688884 16761898
MESH:D009765 Obesity Clozapine 2.9818515891 19142110
MESH:D010051 Ovarian Neoplasms Mifepristone 5.3616525653
MESH:D010051 Ovarian Neoplasms Urethane 5.3616391232
MESH:D010146 Pain Morphine 4.0515275824 16273134 15215642 20225289 18699797 6776300
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.3616540662
MESH:D010300 Parkinson Disease Dieldrin 3.4616112328 11181820 16809432 17291500 11445065
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0812520081
MESH:D010911 Pituitary Neoplasms Urethane 5.2416391232
MESH:D011041 Poisoning Diazinon 8.4817603234
MESH:D011041 Poisoning Mustard Gas 8.4815727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3918163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.412563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0211222880 11896295 11399792 11118676
MESH:D011537 Pruritus Mustard Gas 3.9218058305
MESH:D011595 Psychomotor Agitation Haloperidol 4.7811575062
MESH:D011618 Psychotic Disorders Clozapine 8.7515331141
MESH:D011618 Psychotic Disorders Haloperidol 8.7511575062
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.8617266442 17620002 17894541 17720292 10334151
MESH:D015427 Reperfusion Injury Morphine 4.0519211983
MESH:D012135 Respiratory Sounds Chlorpyrifos 4.4711874814 16611668 17119214
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6718990726
MESH:D012140 Respiratory Tract Diseases Chlorpyrifos 4.7216611668 17119214
MESH:D012559 Schizophrenia Clozapine 4.0118855531 16141801 20521326 20168265 20580759 20521320 20452607 19369910 17726453 17123785 20107430 17667964 11151749 18806925 11763009
MESH:D012559 Schizophrenia Haloperidol 4.0119369910 1830565 18513383 20107430
MESH:D012640 Seizures Kainic Acid 6.871641125 10686065 14637104 19414003 16336964 18657176 15686955 17827730 19186208
MESH:D012640 Seizures Pilocarpine 6.877750514 19660546
MESH:D012729 Sex Chromosome Aberrations Chlorpyrifos 5.926418539
MESH:D012871 Skin Diseases Mustard Gas 2.6716961503 12880345 15451306
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.7016192470
MESH:D012878 Skin Neoplasms Urethane 5.7011807781
MESH:D012893 Sleep Disorders Kainic Acid 5.5219414003
MESH:D013226 Status Epilepticus Pilocarpine 6.0919430551 11259499 15857427 15987249 19951488 19570321 19055492
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7518456281
MESH:D017180 Tachycardia, Ventricular Haloperidol 4.5420210726
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7312697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 2.867505956
MESH:D014202 Tremor Pilocarpine 5.6317594079
MESH:D014570 Urologic Diseases Diazinon 5.1016487989
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4212125929
MESH:D019043 Vascular Neoplasms Urethane 5.7410620525
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0815886252
MESH:D015430 Weight Gain Clozapine 4.3220564506 17502770 16402076 20107430 16141801 20521320
MESH:D015431 Weight Loss Clozapine 4.9017933447
Pathway ID Pathway Name
KEGG:05014 Amyotrophic lateral sclerosis (ALS)
KEGG:04724 Glutamatergic synapse
KEGG:04730 Long-term depression
KEGG:04720 Long-term potentiation
KEGG:04080 Neuroactive ligand-receptor interaction
REACT:13685 Synaptic Transmission
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28966
    • No data
    Releated disease ID Related disease Name
    PA443936Drug Hypersensitivity
    Releated drug ID Related drug Name
    PA448492asparaginase
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00142 - L-Glutamic Acid Dietary supplement;Micronutrient;Non-Essential Amino Acids
    DB00228 antagonist Enflurane Anesthetics, Inhalation;General Anesthetics
    DB00753 antagonist Isoflurane Anesthetics, Inhalation;General Anesthetics;Anesthetics
    DB01028 antagonist Methoxyflurane Anesthetics, Inhalation
    DB01174 antagonist Phenobarbital Hypnotics and Sedatives;Anticonvulsants;GABA Modulators;Excitatory Amino Acid Antagonists
    DB01189 antagonist Desflurane Anesthetics, Inhalation;Neuroprotective Agents
    DB01236 antagonist Sevoflurane Platelet Aggregation Inhibitors;Anesthetics, Inhalation
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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