AutismKB 2.0

Annotation Detail for FLVCR1


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Basic Information Top
Gene Symbol:FLVCR1 ( FLVCR,MFSD7B )
Gene Full Name: feline leukemia virus subgroup C cellular receptor 1
Band: 1q32.3
Quick LinksEntrez ID:28982; OMIM: 609144; Uniprot ID:FLVC1_HUMAN; ENSEMBL ID: ENSG00000162769; HGNC ID: 24682
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1863Aplastic anemia
2052Infection
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of FLVCR1 mRNAaffects expression 17562736
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of FLVCR1 mRNAdecreases expression 20018196
19150397
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.9110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0420889678
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6811287661 19164858 10915739 12392966 18071297 2444490 12705907 18713872 11421492 11834606 12958197 12540782 19416960 16485898 17906064 19370779 11461765 11739529 16177239 17562736 19085960 15619225 15968718 12153990 19739265 12594235 17522070 10663392 16081117 14550746 14725611 11529661 16781746 16393943 16109766 19923254 19420014 11743745 10774834 16227642 14986274
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1620426865
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4412587719 15629191
MESH:D008107 Liver Diseases Acetaminophen 1.7112969438 16610002 19784758 16611625 19014921 11587558 19460945 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7417185352 16871587
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:C536343 Posterior column ataxia with retinitis pigmentosa marker/mechanism
MESH:D014581 Urticaria Acetaminophen 3.5810982225
Pathway ID Pathway Name
REACT:15518 Transmembrane transport of small molecules
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018