Annotation Detail for SETD2
Basic Information
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| Gene Symbol: | SETD2 ( FLJ16420,FLJ22472,FLJ23184,FLJ45883,FLJ46217,HBP231,HIF-1,HYPB,KIAA1732,KMT3A,SET2,p231HBP ) |
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| Gene Full Name: | SET domain containing 2 |
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| Band: | 3p21.31 |
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| Quick Links | Entrez ID:29072; OMIM: 612778; Uniprot ID:SETD2_HUMAN; ENSEMBL ID: ENSG00000181555; HGNC ID: 18420 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| hsa00310 | Lysine degradation |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of SETD2 mRNA | affects expression | 17562736
|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of SETD2 mRNA | affects expression | 20382639
|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SETD2 mRNA | decreases expression | 19150397
|
| D020122 |
tert-Butylhydroperoxide |
tert-Butylhydroperoxide results in decreased expression of SETD2 mRNA | decreases expression | 15336504
|
| D004997 |
Ethinyl Estradiol |
Ethinyl Estradiol affects the expression of SETD2 mRNA | affects expression | 17555576
|
| D014810 |
Vitamin E |
Vitamin E results in decreased expression of SETD2 mRNA | decreases expression | 19244175
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000152 |
Acne Vulgaris |
|
Ethinyl Estradiol |
4.55 | 17505938 |
| MESH:D000230 |
Adenocarcinoma |
|
Ethinyl Estradiol |
1.88 | 14692618 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.45 | 10982225 |
| MESH:D001161 |
Arteriosclerosis |
|
Ethinyl Estradiol |
3.95 | 11256880 |
| MESH:D001169 |
Arthritis, Experimental |
|
Ethinyl Estradiol |
2.86 | 15885639 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D002252 |
Carbon Tetrachloride Poisoning |
|
Vitamin E |
4.41 | 16050911 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
1.40 | 3084413 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.77 | 10977129 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.96 | 20889678 |
| MESH:D002779 |
Cholestasis |
|
Ethinyl Estradiol |
3.13 | 11677210 16105132 15861022 17681005 17333356 16919318 17110522 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Vitamin E |
1.92 | 19769572 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
1.66 | 17522070 16781746 11529661 16227642 19923254 17906064 12392966 19085960 19420014 14550746 12540782 11739529 19370779 11743745 11421492 15968718 10663392 12705907 16393943 14725611 10774834 16177239 15619225 16081117 16485898 14986274 19164858 10915739 17562736 12153990 12594235 18071297 2444490 11461765 11287661 19739265 16109766 18713872 12958197 11834606 19416960 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.71 | 19426721 |
| MESH:C538011 |
Eales disease |
|
Vitamin E |
5.32 | 9068938 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Ethinyl Estradiol |
3.63 | 12538720 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.14 | 20426865 |
| MESH:D005234 |
Fatty Liver |
|
Ethinyl Estradiol |
3.18 | 15345470 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.29 | 16983495 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Vitamin E |
3.15 | 16080930 |
| MESH:D006548 |
Hernia, Diaphragmatic |
|
Vitamin E |
2.80 | 16490937 16863852 |
| MESH:D019584 |
Hot Flashes |
|
Vitamin E |
4.58 | 14716179 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.99 | 16870215 |
| MESH:D007021 |
Hypospadias |
|
Ethinyl Estradiol |
4.29 | 16569931 16945680 |
| MESH:D007247 |
Infertility, Female |
|
Ethinyl Estradiol |
3.87 | 12013081 |
| MESH:D007248 |
Infertility, Male |
|
Ethinyl Estradiol |
2.71 | 17937319 |
| MESH:D007251 |
Influenza, Human |
|
Vitamin E |
4.83 | 16624496 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
6.58 | 12587719 15629191 |
| MESH:D007674 |
Kidney Diseases |
|
Vitamin E |
6.58 | 12488133 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Vitamin E |
1.90 | 16169303 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.69 | 16610002 16611625 19784758 19014921 12587719 19460945 11587558 12969438 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.58 | 16871587 17185352 |
| MESH:D008171 |
Lung Diseases |
|
Vitamin E |
3.40 | 16863852 |
| MESH:D008175 |
Lung Neoplasms |
|
Vitamin E |
1.90 | 11062179 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.05 | 19513568 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.18 | 18514411 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.69 | 16870215 |
| MESH:D016584 |
Panic Disorder |
|
Ethinyl Estradiol |
4.09 | 11578682 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Vitamin E |
3.25 | 15084515 |
| MESH:D011537 |
Pruritus |
|
Ethinyl Estradiol |
3.85 | 16919318 15861022 |
| MESH:D012871 |
Skin Diseases |
|
Vitamin E |
2.51 | 18709164 |
| MESH:D012878 |
Skin Neoplasms |
|
tert-Butylhydroperoxide |
2.83 | 8532709 |
| MESH:D013088 |
Spermatocele |
|
Ethinyl Estradiol |
4.55 | 16709447 |
| MESH:D020521 |
Stroke |
|
Vitamin E |
3.81 | 16517955 |
| MESH:D019851 |
Thrombophilia |
|
Ethinyl Estradiol |
4.02 | 11994571 |
| MESH:D013927 |
Thrombosis |
|
Ethinyl Estradiol |
3.48 | 15669648 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.38 | 10982225 |
| MESH:D014594 |
Uterine Neoplasms |
|
Ethinyl Estradiol |
3.74 | 14692618 |
| MESH:D020246 |
Venous Thrombosis |
|
Ethinyl Estradiol |
3.91 | 15869587 14671159 |
| Pathway ID |
Pathway Name |
|---|
| KEGG:00310 |
Lysine degradation |
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