AutismKB 2.0

Annotation Detail for DROSHA


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Basic Information Top
Gene Symbol:DROSHA ( ETOHI2,HSA242976,RANSE3L,RN3,RNASE3L,RNASEN )
Gene Full Name: drosha, ribonuclease type III
Band: 5p13.3
Quick LinksEntrez ID:29102; OMIM: 608828; Uniprot ID:RNC_HUMAN; ENSEMBL ID: ENSG00000113360; HGNC ID: 17904
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Regulatory RNA pathways
Pathway IDPathway Name
200101Direct p53 effectors
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1779Cervical cancer
1993Esophagus cancer
2051Leukemia
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of DROSHA mRNAaffects expression 17555576
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 5.3617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.9014692618
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.3711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.9615885639
MESH:D002779 Cholestasis Ethinyl Estradiol 3.2817681005 17110522 16105132 17333356 11677210 15861022 16919318
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.9712538720
MESH:D005234 Fatty Liver Ethinyl Estradiol 3.4415345470
MESH:D007021 Hypospadias Ethinyl Estradiol 4.7216569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 4.1612013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.8217937319
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.3811578682
MESH:D011537 Pruritus Ethinyl Estradiol 4.4016919318 15861022
MESH:D013088 Spermatocele Ethinyl Estradiol 5.3616709447
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.3211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.6815669648
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 4.0814692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 4.1714671159 15869587
Pathway ID Pathway Name
REACT:12472 Regulatory RNA pathways
KEGG:03008 Ribosome biogenesis in eukaryotes
Pharmacogenomics Knowledge Base Top
Drug Bank Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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