AutismKB 2.0

Annotation Detail for GSPT1


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Basic Information Top
Gene Symbol:GSPT1 ( 551G9.2,ETF3A,FLJ38048,FLJ39067,GST1,eRF3a )
Gene Full Name: G1 to S phase transition 1
Band: 16p13.13
Quick LinksEntrez ID:2935; OMIM: 139259; Uniprot ID:ERF3A_HUMAN; ENSEMBL ID: ENSG00000103342; HGNC ID: 4621
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C049325 1,2-dithiol-3-thione 1,2-dithiol-3-thione results in increased expression of GSPT1 mRNAincreases expression 15375163
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of GSPT1 mRNAaffects expression 21346803
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of GSPT1 mRNAincreases expression 20504355
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of GSPT1 mRNAdecreases expression 19150397
20018196
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of GSPT1 mRNAincreases expression 15336504
D016572 Cyclosporine Cyclosporine results in increased expression of GSPT1 mRNAincreases expression 20106945
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of GSPT1 mRNAincreases expression 16636312
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of GSPT1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of GSPT1 mRNAincreases expression 16174780
17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GSPT1 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of GSPT1 mRNAincreases expression 16174780
D005472 Fluorouracil TP53 protein affects the reaction [Fluorouracil results in decreased expression of GSPT1 mRNA]affects reaction|decreases expression 15016801
D015741 Metribolone Metribolone results in increased expression of GSPT1 proteinincreases expression 17152098
C006253 pirinixic acid pirinixic acid results in decreased expression of GSPT1 mRNAdecreases expression 18445702
C059514 resveratrol resveratrol results in decreased expression of GSPT1 mRNAdecreases expression 12002526
D013629 Tamoxifen Tamoxifen affects the expression of GSPT1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GSPT1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of GSPT1 mRNAincreases expression 17942748
D014501 Uranium Uranium results in increased expression of GSPT1 mRNAincreases expression 15672453
C005460 uranyl acetate uranyl acetate results in increased expression of GSPT1 mRNAincreases expression 15672453
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.5814745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.8715322242 11752688 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9717505938
MESH:D058186 Acute Kidney Injury resveratrol 3.8516538975
MESH:D055371 Acute Lung Injury pirinixic acid 3.1218653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 7.0520127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 7.0514692618
MESH:D000230 Adenocarcinoma Fluorouracil 7.0517638652
MESH:D000236 Adenoma Benzo(a)pyrene 6.816695378
MESH:D000236 Adenoma resveratrol 6.8115688382
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.9716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.9716835633
MESH:D000544 Alzheimer Disease resveratrol 2.5716183991 16162502
MESH:D000686 Amyloidosis Diethylstilbestrol 4.4915469931
MESH:D000740 Anemia Fluorouracil 8.6915504547 17963324 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.6911748828
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.0919183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.3715885639
MESH:D001169 Arthritis, Experimental resveratrol 7.3717115116
MESH:D050197 Atherosclerosis resveratrol 3.2717967414 16873680
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.7819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.7812125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7615746008
MESH:D002545 Brain Ischemia resveratrol 4.3017600658
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.9617474063 20146248
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.9615324884 17129689
MESH:D001943 Breast Neoplasms Fluorouracil 2.9618608205 19217205 16557594 15136595 16595493 16110121 18357371
MESH:D001943 Breast Neoplasms resveratrol 2.9617651959 16393696 17534123
MESH:D001943 Breast Neoplasms Tamoxifen 2.9618821012 19189212 20065188 16202921 19155303 19084267 11161223 19115204 20135344 19189210 18351453 18855134 18997820 19142967 21152245 19221464 19410462 15668708 19059307 18629630 20005174 17893378 21138602 18815881 17261762 20544844 17049068 19011961 17242785 15565566 19288272 19244106 19200415 19289846 16873071 18425577 16273361 20859285 19103187 16818667 20390343 19066611 17440819 19487384 18984771
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.9620435547
MESH:D002276 Carcinoid Tumor Fluorouracil 4.7016051944
MESH:D002277 Carcinoma Fluorouracil 8.1917121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.1916835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5219066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 8.9016705839
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 8.9015948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 8.9017045692 16799960 16332177 17088986 17971768 18930000
MESH:D006528 Carcinoma, Hepatocellular resveratrol 8.9016227395 19321006
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 8.9016924424
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.6116675471
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 3.0218695887
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.5920419170
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 7.5916757204 17066447 18986760 16280240
MESH:D002294 Carcinoma, Squamous Cell resveratrol 7.5916227395
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.6217572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3718850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases resveratrol 3.4715458977
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.5620889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.5612371664
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1616835633
MESH:D002779 Cholestasis Cyclosporine 13.3619486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.3616919318 11677210 17681005 17333356 16105132 15861022 17110522
MESH:D002779 Cholestasis pirinixic acid 13.3619176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1012621046 8697196 15668235 15340226 16354765
MESH:D003092 Colitis resveratrol 4.1416474422
MESH:D003110 Colonic Neoplasms Fluorouracil 3.9216510598 17172411 15001691 17018589 17725105 16340194 17169374 18772588 17287894 17016597
MESH:D003110 Colonic Neoplasms resveratrol 3.9216338953
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.6820501625 16331619 18802399 15289873 16524972 14970324 17695437 17255274 18383874 18448328 16282729 18949393 18509181 16391804 17401013 18288408 17454858 17594712 16303861 17016601 15148649 17094418
MESH:D015179 Colorectal Neoplasms resveratrol 2.6816550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0617141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.7516507316
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2515322242 20055451 10048152
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.5712952375 16002989
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.0318551238
MESH:D007644 Darier Disease Fluorouracil 4.8116733453
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3819031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4318249437
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.7716873680
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6717107852
MESH:D003928 Diabetic Nephropathies resveratrol 9.0516286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 9.0519279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 3.7018551238 21346803
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.7020420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7611462148
MESH:D004487 Edema pirinixic acid 11.4612083418
MESH:D004487 Edema resveratrol 11.468985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.4611000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9315322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.4212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 15.4217872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 15.4219031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.7116402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 7.5715700306 16804899
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.5716202921 19155303 20544844 17893378
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.029294722 10568697
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.8617923197
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.2320426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 7.2316530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 7.2316337965 17638652 15173087 16785472 16481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0111564622
MESH:D005234 Fatty Liver Cyclosporine 18.7819224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 18.7815345470
MESH:D005234 Fatty Liver pirinixic acid 18.7820131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 18.7819224547 14986274
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 8.2216002989 16611131 15751030 16513791 16534752
MESH:D052776 Female Urogenital Diseases Tamoxifen 8.2216709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4711858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.5514745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.2019069698
MESH:D005355 Fibrosis Cyclosporine 8.5312639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.5320067830
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.9716452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.248708960
MESH:D005910 Glioma Fluorouracil 2.8716145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6210696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.3915162350 15102660 18337622
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.4520471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.4511294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.5420558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.4415720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3411000095
MESH:D006529 Hepatomegaly pirinixic acid 8.3119176532 18467677 19772884 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.3112621046 15340226 16120746
MESH:D006561 Herpes Simplex resveratrol 4.2016876885
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0816959395 15340226 18606429 8697196 16354765
MESH:D006937 Hypercholesterolemia resveratrol 4.0117188708
MESH:D006943 Hyperglycemia pirinixic acid 3.1920558911
MESH:D006949 Hyperlipidemias resveratrol 4.0316873680
MESH:D006965 Hyperplasia Diethylstilbestrol 4.4512960047 14722030
MESH:D006973 Hypertension Cyclosporine 4.9510903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.9518850075 18670907
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.3117488730
MESH:D007021 Hypospadias Diethylstilbestrol 11.2916002989
MESH:D007021 Hypospadias Ethinyl Estradiol 11.2916569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.6617600658
MESH:D007246 Infertility Diethylstilbestrol 4.3615036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4917937319
MESH:D007249 Inflammation resveratrol 8.3416366677
MESH:D007249 Inflammation Tamoxifen 8.3419457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.3412200463 12878042
MESH:D007251 Influenza, Human resveratrol 4.5716624496
MESH:D007333 Insulin Resistance pirinixic acid 2.6316306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3416580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.4715604871
MESH:D007674 Kidney Diseases Cyclosporine 2.3418776723 10903974 8314463
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 23.3816705839
MESH:D007680 Kidney Neoplasms Cyclosporine 23.3812371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 23.3816762066 14681315 15003126
MESH:D007680 Kidney Neoplasms Fluorouracil 23.3816985049
MESH:D007680 Kidney Neoplasms Tamoxifen 23.3818625569
MESH:D007859 Learning Disorders Diethylstilbestrol 4.0717184923
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.5816087638
MESH:D008064 Lipidoses Tamoxifen 3.1617567588 15342952
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.3915474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 3.3918564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.3912878042
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 21.9521137059 20195826
MESH:D008113 Liver Neoplasms Diethylstilbestrol 21.9516712894 15890375
MESH:D008113 Liver Neoplasms Fluorouracil 21.9516603448 17045692 18383874 15113037
MESH:D008113 Liver Neoplasms pirinixic acid 21.9516377806 15890375 20007298
MESH:D008113 Liver Neoplasms resveratrol 21.9519073162 19812893 20405173 19321006
MESH:D008113 Liver Neoplasms Tamoxifen 21.9516684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 21.9516984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.1112151625
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 4.8320135361 18569708 20869020 18816296 17053015 18520028 20064080 20464547 6695378
MESH:D008175 Lung Neoplasms Fluorouracil 4.8315246190
MESH:D008175 Lung Neoplasms Tamoxifen 4.8318625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8311884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.8115086387
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.1715166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.4715700306
MESH:D016393 Lymphoma, B-Cell resveratrol 4.3117088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.8714749477
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.5516002989
MESH:D015674 Mammary Neoplasms, Animal resveratrol 10.0715688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 10.0719428831
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 6.188985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 6.1819196722 14580682 19196723 11731420 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 4.5819453300
MESH:D008545 Melanoma resveratrol 3.4417992120
MESH:D008545 Melanoma Tamoxifen 3.4412393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.2015990972
MESH:D008659 Metabolic Diseases resveratrol 4.3817112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.8216801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.5416381670
MESH:D009062 Mouth Neoplasms Fluorouracil 8.5418986760 16757204
MESH:D009101 Multiple Myeloma resveratrol 3.4717164350 17935668 16490592 14749477 17049120 16267019
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.8917962980
MESH:D009135 Muscular Diseases pirinixic acid 3.5216239165
MESH:D009203 Myocardial Infarction pirinixic acid 5.7419151258
MESH:D009203 Myocardial Infarction resveratrol 5.7416525036 16456233 17188708 16317513 17125593 17015251
MESH:D017202 Myocardial Ischemia resveratrol 9.0217125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 9.0212213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9516411023
MESH:D009205 Myocarditis resveratrol 4.7817322642
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.8818551238
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.5519393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5219410462
MESH:D009369 Neoplasms Benzo(a)pyrene 11.8811141357
MESH:D009369 Neoplasms Diethylstilbestrol 11.8815313581
MESH:D009369 Neoplasms Fluorouracil 11.8818600527 16928823 18239605
MESH:D009369 Neoplasms pirinixic acid 11.8817405874
MESH:D009374 Neoplasms, Experimental resveratrol 4.018985016
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.0319189210 19200415 19196722
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.4717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2919348381 18481113
MESH:D009421 Nervous System Malformations Diethylstilbestrol 9.6711399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.6714600291
MESH:D019636 Neurodegenerative Diseases resveratrol 3.8117652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.4117929310
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.4416436463
MESH:D009765 Obesity pirinixic acid 1.8120558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.4316049721 12819281
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.2617513867
MESH:D010190 Pancreatic Neoplasms Fluorouracil 2.6619003803 16929163 16500647 15113037
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6911578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2812520081
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.2014722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.6815687265 16977796
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5718163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.2212371664
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 16.4517184923
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 16.4516679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 16.4511896295 11118676 11399792 11222880
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.8717292933
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 1.8715846301 17136230 15046698
MESH:D011471 Prostatic Neoplasms Fluorouracil 1.8718626508 19082440
MESH:D011471 Prostatic Neoplasms resveratrol 1.8715767336 17675339 16731767 17804756 17718901 17636462
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8715067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.3315861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.2316882103
MESH:D012004 Rectal Neoplasms Fluorouracil 4.0118722050 16160472 18286688 15538739
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.6116325855
MESH:D015427 Reperfusion Injury pirinixic acid 6.5819058328
MESH:D015427 Reperfusion Injury resveratrol 6.5817058453 16314181 15827377 16317513 17520802
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8518990726
MESH:D012640 Seizures 2,4-dinitrotoluene 2.5318551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 13.5819755658 10029692
MESH:D012878 Skin Neoplasms resveratrol 13.5815837718 8985016
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 13.588532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 13.5816192470
MESH:D013088 Spermatocele Diethylstilbestrol 20.3316709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 20.3316709447
MESH:D013088 Spermatocele Tamoxifen 20.3316709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0619457130
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.4220155912 2093021
MESH:D013274 Stomach Neoplasms Fluorouracil 2.4219015929 17522103 15786421 18396642 17172411 16424979 16951190 19084572 17498489 18567086
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.4816321402
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6311994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1515669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9312697716
MESH:D014062 Tongue Neoplasms Fluorouracil 10.0016280240
MESH:D014062 Tongue Neoplasms resveratrol 10.0016227395
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 11.9416049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 11.9417053015
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 11.9417306315 16712894 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 11.9416712894 8653321 17572228
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.3310091137
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 15.9816175088
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 15.9816803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 15.9817473185
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.2014652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 16.1415809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 16.1414692618
MESH:D014594 Uterine Neoplasms resveratrol 16.1417044934
MESH:D014605 Uveitis Cyclosporine 4.011336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.4516002989 16513791
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5414671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.3117488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2815886252
MESH:D014985 Xerophthalmia Cyclosporine 4.4717120751
Pathway ID Pathway Name
KEGG:03015 mRNA surveillance pathway
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB04315 - Guanosine-5'-Diphosphate
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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