AutismKB 2.0

Annotation Detail for GSTM1


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Basic Information Top
Gene Symbol:GSTM1 ( GST1,GSTM1-1,GSTM1a-1a,GSTM1b-1b,GTH4,GTM1,H-B,MGC26563,MU,MU-1 )
Gene Full Name: glutathione S-transferase mu 1
Band: 1p13.3
Quick LinksEntrez ID:2944; OMIM: 138350; Uniprot ID:GSTM1_HUMAN; ENSEMBL ID: ENSG00000134184; HGNC ID: 4632
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-4061glutathione-mediated detoxification
Pathway IDPathway Name
hsa00480Glutathione metabolism
hsa00980Metabolism of xenobiotics by cytochrome P450
hsa00982Drug metabolism - cytochrome P450
Pathway IDPathway Name
Biological oxidations
Pathway IDPathway Name
200130C-MYB transcription factor network
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1709Parkinson disease
1724Vascular disease
1739Oral cancer
1754Actinic keratosis
1777Intractable epilepsy
1781Rheumatoid arthritis
1803Periodontitis
1804Chronic obstructive airway disease
1811Drug-Induced dyskinesia
1820Kuhnt-Junius degeneration
1863Aplastic anemia
1869Behcet syndrome
1870Drug abuse
1871Hepatitis
1872Chronic simple glaucoma
1877Multiple sclerosis
1901Endometriosis
1902Kidney failure
1904Diabetes mellitus
1914Cerebrovascular disorder
1918Atherosclerosis
1932Pancreatitis
1934Cancer
1954Stroke
1979Testicular dysfunction
1995Varicosity
2029Tuberculosis
2044Pre-Eclampsia
2050Peptic esophagitis
2057Premature birth
2069Schizophrenia
2074Asthma
1823Infertility, Male
2102Polycystic ovary syndrome
2123Vitiligo
2124Autistic disorder
2164Barrett's esophagus
2207Deafness
2220Dermatitis
2241Infertility
Desease Name
oral cancer
Parkinson's disease
leukemia, myeloid
cirrhosis
AGING
tuberculosis
colorectal cancer
endometriosis
azathioprine adverse effects
lymphoma
liver cancer
PAH metabolites, urinary
coke-oven toxicity
prostate cancer
aflatoxin-related hepatocarcinogenesis
CANCER
PSYCH
PHARMACOGENOMIC
nasopharyngeal cancer
urinary PAH metabolites
benzene toxicity
Asthma
bladder cancer
esophageal cancer
liver injury, drug-induced
arsenic metabolism
breast cancer
methotrexate toxicity
Haematological Neoplasias
asbestos-associated pulmonary disorders
IMMUNE
NEUROLOGICAL
solar keratosis
glaucoma, primary open-angle
chronic toxic encephalopathy
thimerosal sensitization
schizophrenia
METABOLIC
Upper aerodigestive tract cancers
Stomach Neoplasms
colorectal cancer stomach cancer
metastatic colorectal cancer
VISION
chronic obstructive pulmonary disease/COPD
hepatocellular carcinoma
high inducibility of cytochrome P450 1A1 gene transcription
lung cancer
hepatitis B
leukemia
REPRODUCTION
GSTM1 methylation infertility, male
longevity
Fetal Growth Retardation
Autism
cytogenetic studies
oral clefting
oxidative stress
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C026486 1,2,5,6-dibenzanthracene GSTM1 protein affects the metabolism of [1,2,5,6-dibenzanthracene co-treated with Glutathione]affects cotreatment|affects metabolic processing 9403173
C012277 1,2-diamino-4-nitrobenzene 1,2-diamino-4-nitrobenzene results in increased expression of GSTM1 mRNAincreases expression 17070881
C028328 1,2-dichloro-4-nitrobenzene GSTM1 protein affects the metabolism of 1,2-dichloro-4-nitrobenzeneaffects metabolic processing 1859377
C028328 1,2-dichloro-4-nitrobenzene GSTM1 protein affects the metabolism of 1,2-dichloro-4-nitrobenzeneaffects metabolic processing 7733673
C040756 1,2-naphthoquinone GSTM1 protein results in decreased susceptibility to 1,2-naphthoquinonedecreases response to substance 10661898
C031763 1,3-butadiene GSTM1 gene polymorphism promotes the reaction [EPHX1 gene polymorphism results in increased susceptibility to 1,3-butadiene]increases reaction|increases response to substance 11238181
C097240 15-deoxy-delta(12,14)-prostaglandin J2 GSTM1 protein affects the metabolism of [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Glutathione]affects cotreatment|affects metabolic processing 14979731
C015262 1,6-hexamethylene diisocyanate GSTM1 protein polymorphism results in increased susceptibility to 1,6-hexamethylene diisocyanateincreases response to substance 11927838
C042630 1-chloro-2,4-dinitrobenzene-glutathione conjugate GSTM1 protein affects the metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugateaffects metabolic processing 11684093
C035314 1-nitropropane 1-nitropropane results in decreased expression of GSTM1 mRNAdecreases expression 17070881
C010914 2,4-diaminotoluene 2,4-diaminotoluene results in increased expression of GSTM1 mRNAincreases expression 17070881
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of GSTM1 mRNAaffects expression 21346803
C009497 2-(4-toluidino)-6-naphthalenesulfonic acid 2-(4-toluidino)-6-naphthalenesulfonic acid binds to GSTM1 proteinaffects binding 7725348
C025235 2,6-diaminotoluene 2,6-diaminotoluene results in decreased expression of GSTM1 mRNAdecreases expression 17070881
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of GSTM1 mRNAaffects expression 21346803
C099328 2-allylphenol 2-allylphenol results in decreased activity of GSTM1 proteindecreases activity 8620581
C099328 2-allylphenol 2-allylphenol results in decreased activity of GSTM1 proteindecreases activity 8620581
C035208 2-amino-4,6-dinitrotoluene 2-amino-4,6-dinitrotoluene affects the expression of GSTM1 mRNAaffects expression 21346803
C014706 2-nitro-4-phenylenediamine 2-nitro-4-phenylenediamine results in increased expression of GSTM1 mRNAincreases expression 17070881
C016617 2-nitropropane 2-nitropropane results in increased expression of GSTM1 mRNAincreases expression 17070881
C082398 2-S-glutathionylcaffeic acid 2-S-glutathionylcaffeic acid results in decreased activity of GSTM1 proteindecreases activity 8340025
C053603 3-methylpyridine 3-methylpyridine results in decreased expression of GSTM1 proteindecreases expression 7986210
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of GSTM1 mRNAdecreases expression 18648102
C005969 4,4'-diphenylmethane diisocyanate GSTM1 protein polymorphism results in increased susceptibility to 4,4'-diphenylmethane diisocyanateincreases response to substance 11927838
C028676 4-acetylaminofluorene 4-acetylaminofluorene results in increased expression of GSTM1 mRNAincreases expression 17070881
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of GSTM1 mRNAaffects expression 21346803
C010407 4-chloronitrobenzene GSTM1 protein affects the metabolism of [4-chloronitrobenzene analog co-treated with Glutathione]affects cotreatment|affects metabolic processing 8867999
C010407 4-chloronitrobenzene GSTM1 protein affects the metabolism of [4-chloronitrobenzene analog co-treated with Glutathione]affects cotreatment|affects metabolic processing 8973562
C027576 4-hydroxy-2-nonenal GSTM1 protein affects the metabolism of 4-hydroxy-2-nonenal analogaffects metabolic processing 11256969
C027576 4-hydroxy-2-nonenal [GSTM1 protein binds to GSTM2 protein] which affects the metabolism of 4-hydroxy-2-nonenal analogaffects binding|affects metabolic processing 11256969
C027576 4-hydroxy-2-nonenal [GSTM1 protein binds to GSTM3 protein] which affects the metabolism of 4-hydroxy-2-nonenal analogaffects binding|affects metabolic processing 11256969
C027576 4-hydroxy-2-nonenal 4-hydroxy-2-nonenal results in increased expression of GSTM1 proteinincreases expression 12020353
C027576 4-hydroxy-2-nonenal GSTM1 protein affects the metabolism of 4-hydroxy-2-nonenal analogaffects metabolic processing 11256969
C027576 4-hydroxy-2-nonenal [GSTM1 protein binds to GSTM2 protein] which affects the metabolism of 4-hydroxy-2-nonenal analogaffects binding|affects metabolic processing 11256969
C002202 4-oxoretinoic acid 4-oxoretinoic acid results in decreased expression of GSTM1 mRNAdecreases expression 15982314
C099327 4-propylphenol 4-propylphenol results in decreased activity of GSTM1 proteindecreases activity 8620581
C099327 4-propylphenol 4-propylphenol results in decreased activity of GSTM1 proteindecreases activity 8620581
C086396 5-S-glutathionyl-alpha-methyldopa 5-S-glutathionyl-alpha-methyldopa results in decreased activity of GSTM1 proteindecreases activity 8131222
C086394 5-S-glutathionyldopamine 5-S-glutathionyldopamine results in decreased activity of GSTM1 proteindecreases activity 8131222
C008450 7-methylguanine GSTM1 gene polymorphism affects the susceptibility to and affects the metabolism of 7-methylguanineaffects metabolic processing|affects response to substance 15066569
C037112 9-deoxy-delta-9-prostaglandin D2 GSTM1 protein affects the metabolism of 9-deoxy-delta-9-prostaglandin D2affects metabolic processing 9084911
D000082 Acetaminophen Acetaminophen results in decreased expression of GSTM1 mRNAdecreases expression 16611625
C109238 acyline acyline results in decreased expression of GSTM1 mRNAdecreases expression 17510436
C006426 aflatoxin B1-2,3-oxide GSTM1 protein affects the metabolism of and results in decreased activity of aflatoxin B1-2,3-oxideaffects metabolic processing|decreases activity 1638515
D000348 Aflatoxins GSTM1 gene polymorphism results in increased susceptibility to Aflatoxinsincreases response to substance 15734960
C103303 alitretinoin alitretinoin results in decreased expression of GSTM1 mRNAdecreases expression 15982314
C004471 allyl isothiocyanate GSTM1 protein affects the metabolism of allyl isothiocyanateaffects metabolic processing 7826396
C038491 allyl sulfide allyl sulfide results in increased expression of GSTM1 mRNAincreases expression 8627517
C038491 allyl sulfide allyl sulfide results in increased expression of GSTM1 proteinincreases expression 8627517
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GSTM1 mRNAaffects expression 16483693
C019257 angelica lactone angelica lactone results in increased expression of GSTM1 proteinincreases expression 11309284
D001151 Arsenic GSTM1 gene mutant form results in decreased susceptibility to Arsenicdecreases response to substance 16353154
D001151 Arsenic GSTM1 gene polymorphism affects the metabolism of and affects the susceptibility to Arsenicaffects metabolic processing|affects response to substance 17365577
D001151 Arsenic GSTM1 polymorphism affects the metabolism of Arsenicaffects metabolic processing 17365577
D001151 Arsenic GSTM1 protein affects the susceptibility to Arsenicaffects response to substance 18053222
C006632 arsenic trioxide arsenic trioxide results in increased expression of GSTM1 mRNAincreases expression 20458559
C015001 arsenite arsenite results in increased expression of GSTM1 mRNAincreases expression 18929588
D001194 Asbestos GSTM1 gene polymorphism results in increased susceptibility to Asbestosincreases response to substance 18420450
D001205 Ascorbic Acid GSTM1 gene polymorphism affects the susceptibility to [Ascorbic Acid co-treated with tocotrienol, alpha]affects cotreatment|affects response to substance 15668500
D001554 Benzene GSTM1 gene mutant form affects the susceptibility to Benzeneaffects response to substance 14694614
D001554 Benzene GSTM1 gene polymorphism affects the reaction [GSTT1 gene polymorphism affects the reaction [NQO1 gene SNP results in increased susceptibility to Benzene]]affects reaction|increases response to substance 17178637
D001554 Benzene GSTM1 gene polymorphism affects the susceptibility to Benzeneaffects response to substance 15226677
D001554 Benzene GSTM1 gene polymorphism results in increased susceptibility to Benzeneincreases response to substance 15226677
15748501
D001554 Benzene GSTM1 protein affects the metabolism of Benzeneaffects metabolic processing 15226677
D001554 Benzene GSTM1 protein results in increased metabolism of Benzeneincreases metabolic processing 17885617
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 20045035
18164116
D019324 beta-Naphthoflavone isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA]affects cotreatment|decreases reaction|increases expression 20045035
D001564 Benzo(a)pyrene GSTM1 gene polymorphism affects the susceptibility to Benzo(a)pyreneaffects response to substance 15471894
D001564 Benzo(a)pyrene GSTM1 gene polymorphism results in increased susceptibility to Benzo(a)pyreneincreases response to substance 7728947
D001564 Benzo(a)pyrene GSTM1 protein affects the metabolism of [Benzo(a)pyrene co-treated with Glutathione]affects cotreatment|affects metabolic processing 9403173
D001564 Benzo(a)pyrene GSTM1 protein polymorphism affects the metabolism of and affects the activity of Benzo(a)pyreneaffects activity|affects metabolic processing 15298956
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of GSTM1 mRNAincreases expression 20127859
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of GSTM1 mRNAincreases expression 19150397
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide GSTM1 protein affects the metabolism of [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide co-treated with Glutathione]affects cotreatment|affects metabolic processing 9403173
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide GSTM1 protein affects the metabolism of and results in decreased activity of [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide co-treated with Glutathione]affects cotreatment|affects metabolic processing|decreases activity 11849043
C005465 benzothiazole benzothiazole results in increased expression of GSTM1 mRNAincreases expression 8951341
C012771 benzotriazole benzotriazole results in increased expression of GSTM1 mRNAincreases expression 8951341
D001583 Benzoxazoles Benzoxazoles results in increased expression of GSTM1 mRNAincreases expression 8951341
C031403 benzyl isothiocyanate GSTM1 protein affects the metabolism of benzyl isothiocyanateaffects metabolic processing 7826396
C032036 bromobenzene bromobenzene metabolite binds to GSTM1 proteinaffects binding 17305373
C032036 bromobenzene bromobenzene results in increased expression of GSTM1 mRNAincreases expression 12628495
C026405 bromotriethylstannane bromotriethylstannane inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]affects metabolic processing|decreases reaction 7733673
C026405 bromotriethylstannane bromotriethylstannane results in decreased activity of GSTM1 proteindecreases activity 7733673
D002066 Busulfan GSTM1 gene polymorphism affects the susceptibility to Busulfanaffects response to substance 15142875
D002066 Busulfan GSTM1 protein affects the metabolism of Busulfanaffects metabolic processing 8886613
D002083 Butylated Hydroxyanisole Butylated Hydroxyanisole results in increased expression of GSTM1 proteinincreases expression 11991805
2597111
11309284
D002101 Cacodylic Acid Cacodylic Acid results in increased expression of GSTM1 mRNAincreases expression 16436460
D002101 Cacodylic Acid Cacodylic Acid results in increased expression of GSTM1 proteinincreases expression 16436460
C053400 cafestol [cafestol co-treated with kahweol] results in increased expression of GSTM1 proteinaffects cotreatment|increases expression 11346484
C053400 cafestol [cafestol co-treated with kahweol palmitate] results in increased expression of GSTM1 proteinaffects cotreatment|increases expression 11309284
C040048 caffeic acid caffeic acid results in decreased activity of GSTM1 proteindecreases activity 8340025
D002220 Carbamazepine GSTM1 gene mutant form results in increased susceptibility to Carbamazepineincreases response to substance 17465707
D002246 Carbon Disulfide GSTM1 gene polymorphism affects the metabolism of Carbon Disulfideaffects metabolic processing 17333241
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of GSTM1 proteinincreases expression 15650968
D002251 Carbon Tetrachloride [Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased activity of GSTM1 proteinaffects cotreatment|decreases activity 12725062
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased activity of GSTM1 protein polymorphismdecreases activity 12611589
D002251 Carbon Tetrachloride GSTM1 protein polymorphism affects the susceptibility to Carbon Tetrachlorideaffects response to substance 12611589
D002251 Carbon Tetrachloride Tea inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased activity of GSTM1 protein]affects cotreatment|decreases activity|decreases reaction 12725062
D002509 Cephaloridine Cephaloridine results in increased expression of GSTM1 mRNAincreases expression 18172885
D002699 Chlorambucil GSTM1 protein results in decreased susceptibility to Chlorambucildecreases response to substance 15044619
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in increased expression of GSTM1 mRNAincreases expression 18178546
D004390 Chlorpyrifos Chlorpyrifos affects the expression of GSTM1 mRNAaffects expression 19440498
D004390 Chlorpyrifos Chlorpyrifos results in increased expression of GSTM1 mRNAincreases expression 17452286
C031180 chrysene GSTM1 protein affects the metabolism of [chrysene co-treated with Glutathione]affects cotreatment|affects metabolic processing 9403173
C012842 Cibacron Blue F 3GA Cibacron Blue F 3GA inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]affects metabolic processing|decreases reaction 7733673
C012842 Cibacron Blue F 3GA Cibacron Blue F 3GA results in decreased activity of GSTM1 proteindecreases activity 7733673
C019304 ciprofibrate ciprofibrate results in decreased expression of GSTM1 mRNAdecreases expression 7676460
D003024 Clozapine Clozapine results in increased expression of GSTM1 mRNAincreases expression 15860345
C515714 copper (N-2-hydroxyacetophenone)glycinate copper (N-2-hydroxyacetophenone)glycinate results in decreased expression of GSTM1 proteindecreases expression 16289015
C515714 copper (N-2-hydroxyacetophenone)glycinate [copper (N-2-hydroxyacetophenone)glycinate results in decreased expression of GSTM1 protein] which results in increased susceptibility to Doxorubicindecreases expression|increases response to substance 16289015
C007164 cumene hydroperoxide GSTM1 protein affects the metabolism of cumene hydroperoxideaffects metabolic processing 10973735
C007164 cumene hydroperoxide GSTM1 protein affects the metabolism of cumene hydroperoxideaffects metabolic processing 11684093
C057862 cyanoginosin LR cyanoginosin LR results in decreased expression of GSTM1 mRNAdecreases expression 17383702
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of GSTM1 mRNAincreases expression 17654400
D003545 Cysteine Cysteine affects the expression of GSTM1 mRNAaffects expression 11040448
D003561 Cytarabine GSTM1 gene polymorphism affects the susceptibility to Cytarabineaffects response to substance 15713801
D003630 Daunorubicin GSTM1 gene polymorphism affects the susceptibility to Daunorubicinaffects response to substance 15713801
D003907 Dexamethasone Dexamethasone results in increased expression of GSTM1 mRNAincreases expression 1394205
D003976 Diazinon Diazinon results in increased expression of GSTM1 mRNAincreases expression 17452286
C041517 dibenzo(a,l)pyrene GSTM1 protein affects the metabolism of and results in decreased activity of [dibenzo(a,l)pyrene co-treated with Glutathione]affects cotreatment|affects metabolic processing|decreases activity 11849043
C061481 dibenzoylmethane dibenzoylmethane results in increased expression of GSTM1 mRNAincreases expression 17942926
C061481 dibenzoylmethane [sulforafan co-treated with dibenzoylmethane] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 17942926
D002945 Cisplatin GSTM1 gene polymorphism affects the susceptibility to [Paclitaxel co-treated with Cisplatin]affects cotreatment|affects response to substance 12851839
D002945 Cisplatin GSTM1 protein affects the susceptibility to Cisplatinaffects response to substance 16217747
C121718 dicyclanil dicyclanil results in increased expression of GSTM1 mRNAincreases expression 15664270
D004041 Dietary Fats [Dietary Fats co-treated with Thioctic Acid] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 18367378
D004052 Diethylnitrosamine [Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased activity of GSTM1 proteinaffects cotreatment|decreases activity 12725062
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 20045035
18164116
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM1 mRNAaffects cotreatment|decreases expression 18544905
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 18544905
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 20033131
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 20033131
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 20033131
D004052 Diethylnitrosamine isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA]affects cotreatment|decreases reaction|increases expression 20045035
D004052 Diethylnitrosamine [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 18754104
D004052 Diethylnitrosamine [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of GSTM1 proteinaffects cotreatment|increases expression 20935162
D004052 Diethylnitrosamine Tea inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased activity of GSTM1 protein]affects cotreatment|decreases activity|decreases reaction 12725062
D004121 Dimethyl Sulfoxide Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in decreased expression of GSTM1 protein]decreases expression|decreases reaction 12370186
D004137 Dinitrochlorobenzene GSTM1 protein affects the metabolism of Dinitrochlorobenzeneaffects metabolic processing 14508638
D004137 Dinitrochlorobenzene GSTM1 protein affects the metabolism of Dinitrochlorobenzeneaffects metabolic processing 9571047
D004137 Dinitrochlorobenzene GSTM1 protein affects the metabolism of Dinitrochlorobenzeneaffects metabolic processing 9545290
3570286
D004137 Dinitrochlorobenzene GSTM1 protein affects the metabolism of Dinitrochlorobenzeneaffects metabolic processing 12069689
D004137 Dinitrochlorobenzene bromotriethylstannane inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]affects metabolic processing|decreases reaction 7733673
D004137 Dinitrochlorobenzene Cibacron Blue F 3GA inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]affects metabolic processing|decreases reaction 7733673
D004137 Dinitrochlorobenzene Hemin inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]affects metabolic processing|decreases reaction 7733673
D004137 Dinitrochlorobenzene Sulfobromophthalein inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]affects metabolic processing|decreases reaction 7733673
D004137 Dinitrochlorobenzene triphenyltin chloride inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]affects metabolic processing|decreases reaction 7733673
D004137 Dinitrochlorobenzene GSTM1 protein affects the metabolism of Dinitrochlorobenzeneaffects metabolic processing 11368767
D004137 Dinitrochlorobenzene GSTM1 protein affects the metabolism of [Dinitrochlorobenzene analog co-treated with Glutathione]affects cotreatment|affects metabolic processing 8867999
D004137 Dinitrochlorobenzene GSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione]affects cotreatment|affects metabolic processing 2375757
D004137 Dinitrochlorobenzene GSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog]affects cotreatment|affects metabolic processing 2375757
D004137 Dinitrochlorobenzene GSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog]affects cotreatment|affects metabolic processing 2904809
D004178 Diquat Diquat results in decreased expression of GSTM1 mRNAdecreases expression 7676460
D004050 Ditiocarb Ditiocarb binds to and results in decreased activity of GSTM1 proteinaffects binding|decreases activity 6095330
D004298 Dopamine Dopamine analog results in decreased activity of GSTM1 proteindecreases activity 8131222
D004317 Doxorubicin [copper (N-2-hydroxyacetophenone)glycinate results in decreased expression of GSTM1 protein] which results in increased susceptibility to Doxorubicindecreases expression|increases response to substance 16289015
D004317 Doxorubicin Doxorubicin results in increased expression of GSTM1 mRNAincreases expression 16243910
D004317 Doxorubicin GSTM1 protein results in decreased susceptibility to Doxorubicindecreases response to substance 16289015
C042986 ebselen ebselen binds to and results in decreased activity of [GSTM1 protein binds to GSTM2 protein]affects binding|decreases activity 8147899
D004811 Epichlorohydrin GSTM1 gene polymorphism affects the susceptibility to Epichlorohydrinaffects response to substance 15091291
D002393 Estrogens, Catechol GSTM1 protein affects the metabolism of Estrogens, Catechol metaboliteaffects metabolic processing 15455371
D004976 Ethacrynic Acid GSTM1 protein affects the metabolism of Ethacrynic Acidaffects metabolic processing 12069689
D000431 Ethanol GSTM1 gene polymorphism affects the susceptibility to Ethanolaffects response to substance 15932176
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of GSTM1 mRNAaffects expression 17351261
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of GSTM1 mRNAdecreases expression 15834898
D005015 Ethoxyquin Ethoxyquin results in increased expression of GSTM1 proteinincreases expression 11309284
D005015 Ethoxyquin Ethoxyquin results in increased expression of GSTM1 proteinincreases expression 8198522
D005034 Ethylmercuric Chloride Ethylmercuric Chloride results in decreased activity of GSTM1 proteindecreases activity 1793546
D005047 Etoposide GSTM1 gene polymorphism affects the susceptibility to Etoposideaffects response to substance 15713801
D005054 Eugenol Eugenol analog results in decreased activity of GSTM1 proteindecreases activity 8620581
D005054 Eugenol Eugenol analog results in decreased activity of GSTM1 proteindecreases activity 8620581
D005227 Fatty Acids Fatty Acids binds to and results in increased activity of GSTM1 proteinaffects binding|increases activity 2277038
D015525 Fatty Acids, Omega-3 GSTM1 gene polymorphism affects the susceptibility to Fatty Acids, Omega-3affects response to substance 15256483
D015725 Fluconazole Fluconazole results in increased expression of GSTM1 mRNAincreases expression 16730040
D015073 2-Acetylaminofluorene 2-Acetylaminofluorene results in increased expression of GSTM1 mRNAincreases expression 17070881
C056933 fumonisin B1 fumonisin B1 results in increased expression of GSTM1 mRNAincreases expression 16221962
C007835 geniposide geniposide results in increased expression of GSTM1 mRNAincreases expression 14646352
C007835 geniposide geniposide results in increased expression of GSTM1 proteinincreases expression 14646352
D005961 Glucosinolates Glucosinolates results in increased expression of GSTM1 proteinincreases expression 15570060
D005978 Glutathione GSTM1 protein affects the metabolism of Glutathioneaffects metabolic processing 10973735
D005978 Glutathione GSTM1 protein affects the metabolism of [1,2,5,6-dibenzanthracene co-treated with Glutathione]affects cotreatment|affects metabolic processing 9403173
D005978 Glutathione GSTM1 protein affects the metabolism of [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Glutathione]affects cotreatment|affects metabolic processing 14979731
D005978 Glutathione GSTM1 protein affects the metabolism of [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide co-treated with Glutathione]affects cotreatment|affects metabolic processing 9403173
D005978 Glutathione GSTM1 protein affects the metabolism of and results in decreased activity of [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide co-treated with Glutathione]affects cotreatment|affects metabolic processing|decreases activity 11849043
D005978 Glutathione GSTM1 protein affects the metabolism of and results in decreased activity of [dibenzo(a,l)pyrene co-treated with Glutathione]affects cotreatment|affects metabolic processing|decreases activity 11849043
D005978 Glutathione GSTM1 protein affects the metabolism of [Benzo(a)pyrene co-treated with Glutathione]affects cotreatment|affects metabolic processing 9403173
D005978 Glutathione GSTM1 protein affects the metabolism of [chrysene co-treated with Glutathione]affects cotreatment|affects metabolic processing 9403173
D005978 Glutathione GSTM1 protein affects the metabolism of Glutathioneaffects metabolic processing 8886613
9084911
9545290
7826396
D005978 Glutathione GSTM1 protein affects the metabolism of [hydratropic aldehyde co-treated with Glutathione]affects cotreatment|affects metabolic processing 11368548
D005978 Glutathione GSTM1 protein affects the metabolism of [4-chloronitrobenzene analog co-treated with Glutathione]affects cotreatment|affects metabolic processing 8867999
D005978 Glutathione GSTM1 protein affects the metabolism of [Dinitrochlorobenzene analog co-treated with Glutathione]affects cotreatment|affects metabolic processing 8867999
D005978 Glutathione GSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione]affects cotreatment|affects metabolic processing 2375757
D005978 Glutathione GSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog]affects cotreatment|affects metabolic processing 2375757
D005978 Glutathione Glutathione analog binds to and results in decreased activity of GSTM1 proteinaffects binding|decreases activity 1883342
D005978 Glutathione Glutathione deficiency results in increased expression of GSTM1 mRNAincreases expression 15345336
D005978 Glutathione GSTM1 protein affects the metabolism of [4-chloronitrobenzene analog co-treated with Glutathione]affects cotreatment|affects metabolic processing 8973562
D005978 Glutathione GSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog]affects cotreatment|affects metabolic processing 2904809
D005978 Glutathione GSTM1 protein affects the metabolism of Glutathioneaffects metabolic processing 6095330
D005978 Glutathione GSTM1 protein affects the metabolism of [styrene oxide co-treated with Glutathione]affects cotreatment|affects metabolic processing 2604743
D006016 Glycolates Glycolates analog binds to and results in decreased activity of GSTM1 proteinaffects binding|decreases activity 6686184
D006220 Haloperidol Haloperidol results in increased expression of GSTM1 mRNAincreases expression 15860345
D006427 Hemin Hemin inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]affects metabolic processing|decreases reaction 7733673
D006427 Hemin Hemin results in decreased activity of GSTM1 proteindecreases activity 7733673
D006540 Herbicides Herbicides binds to and results in decreased activity of GSTM1 proteinaffects binding|decreases activity 6686184
D006581 Hexachlorobenzene Hexachlorobenzene results in decreased expression of GSTM1 mRNAdecreases expression 15159207
C033550 hexylglutathione hexylglutathione binds to and results in decreased activity of GSTM1 proteinaffects binding|decreases activity 9571047
C013026 hydratropic aldehyde GSTM1 protein affects the metabolism of [hydratropic aldehyde co-treated with Glutathione]affects cotreatment|affects metabolic processing 11368548
C013026 hydratropic aldehyde GSTM1 protein results in decreased activity of hydratropic aldehydedecreases activity 11368548
C013026 hydratropic aldehyde hydratropic aldehyde results in decreased activity of GSTM1 proteindecreases activity 11368548
D006861 Hydrogen Peroxide GSTM1 protein results in decreased susceptibility to Hydrogen Peroxidedecreases response to substance 10661898
C031927 hydroquinone GSTM1 gene polymorphism affects the susceptibility to hydroquinoneaffects response to substance 15141365
C029899 imidazole imidazole results in increased expression of GSTM1 mRNAincreases expression 8951341
C016517 indole-3-carbinol indole-3-carbinol results in increased expression of GSTM1 proteinincreases expression 11309284
D007213 Indomethacin Indomethacin results in increased expression of GSTM1 mRNAincreases expression 18299717
D007306 Insecticides GSTM1 gene polymorphism affects the susceptibility to Insecticidesaffects response to substance 12930676
D007460 Iodoacetamide Iodoacetamide results in decreased activity of GSTM1 proteindecreases activity 1520269
D007501 Iron Iron results in decreased expression of GSTM1 proteindecreases expression 11755321
D007501 Iron Iron results in increased expression of GSTM1 mRNAincreases expression 11755321
D007501 Iron Iron results in increased expression of GSTM1 proteinincreases expression 11755321
C031050 isomethyleugenol isomethyleugenol results in decreased activity of GSTM1 proteindecreases activity 8620581
C031050 isomethyleugenol isomethyleugenol results in decreased activity of GSTM1 proteindecreases activity 8620581
C016527 isoquercitrin [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 20033131
C016527 isoquercitrin isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA]affects cotreatment|decreases reaction|increases expression 20045035
C053401 kahweol [cafestol co-treated with kahweol] results in increased expression of GSTM1 proteinaffects cotreatment|increases expression 11346484
C033997 kahweol palmitate [cafestol co-treated with kahweol palmitate] results in increased expression of GSTM1 proteinaffects cotreatment|increases expression 11309284
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM1 mRNAaffects cotreatment|decreases expression 18544905
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 18544905
C008261 lead acetate lead acetate affects the localization of GSTM1 proteinaffects localization 9750042
C008261 lead acetate lead acetate results in increased expression of GSTM1 mRNAincreases expression 9750042
C008261 lead acetate lead acetate results in increased expression of GSTM1 proteinincreases expression 9750042
7878682
D008054 Lipid Peroxides GSTM1 protein affects the metabolism of and results in decreased susceptibility to Lipid Peroxidesaffects metabolic processing|decreases response to substance 9576856
D008550 Melatonin [Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 20033131
D015122 6-Mercaptopurine GSTM1 gene polymorphism affects the susceptibility to 6-Mercaptopurineaffects response to substance 15713801
D008627 Mercuric Chloride Mercuric Chloride results in increased expression of GSTM1 proteinincreases expression 9434069
D008670 Metals GSTM1 gene polymorphism affects the susceptibility to Metalsaffects response to substance 14504370
D008694 Methamphetamine GSTM1 gene polymorphism affects the susceptibility to Methamphetamineaffects response to substance 15048646
D008727 Methotrexate GSTM1 gene polymorphism affects the susceptibility to Methotrexateaffects response to substance 15713801
D008750 Methyldopa Methyldopa analog results in decreased activity of GSTM1 proteindecreases activity 8131222
C005223 methyleugenol methyleugenol results in decreased activity of GSTM1 proteindecreases activity 8620581
C005223 methyleugenol methyleugenol results in decreased activity of GSTM1 proteindecreases activity 8620581
C004925 methylmercuric chloride methylmercuric chloride results in decreased activity of GSTM1 proteindecreases activity 1793546
C020300 monomethylarsonic acid monomethylarsonic acid results in increased expression of GSTM1 mRNAincreases expression 16436460
C020300 monomethylarsonic acid monomethylarsonic acid results in increased expression of GSTM1 proteinincreases expression 16436460
D009151 Mustard Gas Mustard Gas results in decreased expression of GSTM1 mRNAdecreases expression 18955075
C031721 naphthalene naphthalene affects the expression of GSTM1 proteinaffects expression 10959795
C014138 octachlorostyrene octachlorostyrene results in increased expression of GSTM1 mRNAincreases expression 18036774
C026209 oltipraz oltipraz results in increased expression of GSTM1 mRNAincreases expression 9203627
C011030 oxfendazole [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 20033131
C011030 oxfendazole [Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 20033131
C011030 oxfendazole [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 20033131
C011030 oxfendazole [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 18754104
D010126 Ozone GSTM1 gene polymorphism promotes the reaction [NQO1 gene SNP results in increased susceptibility to Ozone]increases reaction|increases response to substance 17652311
D010126 Ozone GSTM1 gene SNP affects the reaction [MS4A2 gene SNP affects the susceptibility to Ozone]affects reaction|affects response to substance 18269668
D010126 Ozone GSTM1 gene SNP affects the reaction [TNF gene SNP affects the susceptibility to Ozone]affects reaction|affects response to substance 16456144
D010126 Ozone GSTM1 gene SNP results in increased susceptibility to Ozoneincreases response to substance 16870661
D010126 Ozone GSTM1 protein affects the susceptibility to Ozoneaffects response to substance 11371413
D010126 Ozone Ozone results in decreased expression of GSTM1 mRNAdecreases expression 12763052
D017239 Paclitaxel GSTM1 gene polymorphism affects the susceptibility to [Paclitaxel co-treated with Cisplatin]affects cotreatment|affects response to substance 12851839
D010269 Paraquat Paraquat results in increased expression of GSTM1 mRNAincreases expression 16128001
C023036 perfluorooctanoic acid perfluorooctanoic acid affects the expression of GSTM1 mRNAaffects expression 18281256
C023036 perfluorooctanoic acid perfluorooctanoic acid results in decreased expression of GSTM1 mRNAdecreases expression 18467677
C023036 perfluorooctanoic acid PPARA protein promotes the reaction [perfluorooctanoic acid results in decreased expression of GSTM1 mRNA]decreases expression|increases reaction 18467677
D010575 Pesticides GSTM1 gene polymorphism affects the susceptibility to Pesticidesaffects response to substance 15922524
14504370
C031181 phenanthrene GSTM1 gene polymorphism promotes the reaction [CYP1A1 gene polymorphism results in increased metabolism of phenanthrene]increases metabolic processing|increases reaction 17035385
C058305 phenethyl isothiocyanate GSTM1 protein affects the metabolism of phenethyl isothiocyanateaffects metabolic processing 7826396
D010634 Phenobarbital Phenobarbital results in decreased expression of GSTM1 proteindecreases expression 7986210
D010634 Phenobarbital [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of GSTM1 proteinaffects cotreatment|increases expression 20935162
C509597 phenylpropylene oxide GSTM1 protein affects the metabolism of phenylpropylene oxideaffects metabolic processing 17689871
D010847 Picolines Picolines results in decreased expression of GSTM1 proteindecreases expression 7986210
C004479 pimagedine pimagedine inhibits the reaction [Spermidine results in increased expression of GSTM1 mRNA]decreases reaction|increases expression 12763045
D010882 Piperonyl Butoxide Piperonyl Butoxide results in increased expression of GSTM1 mRNAincreases expression 18544911
D010882 Piperonyl Butoxide Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of GSTM1 mRNA]increases expression|increases reaction 18544911
C006253 pirinixic acid pirinixic acid results in decreased expression of GSTM1 mRNAdecreases expression 18467677
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in decreased expression of GSTM1 mRNA]decreases expression|increases reaction 18467677
D010936 Plant Extracts Plant Extracts results in increased expression of GSTM1 proteinincreases expression 15570060
C095911 polycyclic aromatic hydrocarbons-DNA adduct GSTM1 protein polymorphism results in increased abundance of polycyclic aromatic hydrocarbons-DNA adductincreases abundance 11967624
D011084 Polycyclic Hydrocarbons, Aromatic GSTM1 gene polymorphism affects the susceptibility to Polycyclic Hydrocarbons, Aromaticaffects response to substance 15036119
15466980
15061915
D011084 Polycyclic Hydrocarbons, Aromatic GSTM1 protein affects the metabolism of and results in decreased activity of Polycyclic Hydrocarbons, Aromaticaffects metabolic processing|decreases activity 15122594
D011084 Polycyclic Hydrocarbons, Aromatic GSTM1 protein polymorphism results in increased susceptibility to Polycyclic Hydrocarbons, Aromaticincreases response to substance 11740339
D011084 Polycyclic Hydrocarbons, Aromatic GSTM1 protein results in decreased activity of Polycyclic Hydrocarbons, Aromaticdecreases activity 15122594
D011241 Prednisone GSTM1 gene polymorphism affects the susceptibility to Prednisoneaffects response to substance 15713801
C045950 propiconazole propiconazole affects the expression of GSTM1 mRNAaffects expression 17383973
C100008 prostaglandin A2 GSTM1 protein affects the metabolism of prostaglandin A2affects metabolic processing 9084911
D011719 Pyrazines Pyrazines results in decreased expression of GSTM1 proteindecreases expression 7986210
C031280 pyrazole pyrazole results in increased expression of GSTM1 mRNAincreases expression 17945193
C031280 pyrazole pyrazole results in increased expression of GSTM1 proteinincreases expression 14610226
D011802 Quinidine Quinidine results in decreased activity of GSTM1 proteindecreases activity 11807801
D011803 Quinine Quinine results in decreased activity of GSTM1 proteindecreases activity 11807801
D015474 Isotretinoin Isotretinoin results in decreased expression of GSTM1 mRNAdecreases expression 15982314
D012294 Rifamycins Rifamycins results in decreased expression of GSTM1 proteindecreases expression 7986210
D012982 Sodium, Dietary GSTM1 gene polymorphism affects the susceptibility to Sodium, Dietaryaffects response to substance 14696128
D013095 Spermidine pimagedine inhibits the reaction [Spermidine results in increased expression of GSTM1 mRNA]decreases reaction|increases expression 12763045
D013095 Spermidine Spermidine results in increased expression of GSTM1 mRNAincreases expression 12763045
D020058 Styrene GSTM1 gene polymorphism affects the susceptibility to Styreneaffects response to substance 14979085
12717779
14751678
D020058 Styrene GSTM1 gene polymorphism promotes the reaction [GSTT1 gene polymorphism results in increased susceptibility to Styrene]increases reaction|increases response to substance 12016165
D020058 Styrene GSTM1 gene polymorphism results in increased susceptibility to Styreneincreases response to substance 12016165
D020058 Styrene GSTM1 protein affects the reaction [CYP2E1 protein affects the metabolism of Styrene]affects metabolic processing|affects reaction 12464798
C013690 styrene oxide GSTM1 protein affects the metabolism of styrene oxideaffects metabolic processing 11599931
17689871
C013690 styrene oxide GSTM1 protein results in decreased susceptibility to styrene oxidedecreases response to substance 14698568
11424177
C013690 styrene oxide GSTM1 protein affects the metabolism of styrene oxideaffects metabolic processing 1638515
C013690 styrene oxide GSTM1 protein affects the metabolism of [styrene oxide co-treated with Glutathione]affects cotreatment|affects metabolic processing 2604743
D013442 Sulfinpyrazone Sulfinpyrazone inhibits the reaction [GSTM1 protein results in decreased susceptibility to Vincristine]decreases reaction|decreases response to substance 15044619
D013448 Sulfobromophthalein Sulfobromophthalein inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]affects metabolic processing|decreases reaction 7733673
D013448 Sulfobromophthalein Sulfobromophthalein results in decreased activity of GSTM1 proteindecreases activity 7733673
C016766 sulforafan GSTM1 gene polymorphism affects the susceptibility to sulforafanaffects response to substance 15623468
C016766 sulforafan GSTM1 protein affects the metabolism of sulforafanaffects metabolic processing 7826396
C016766 sulforafan [sulforafan co-treated with dibenzoylmethane] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 17942926
C016766 sulforafan sulforafan results in increased expression of GSTM1 mRNAincreases expression 17942926
C016766 sulforafan sulforafan results in increased expression of GSTM1 proteinincreases expression 11309284
D013457 Sulfur Compounds GSTM1 gene polymorphism affects the susceptibility to Sulfur Compoundsaffects response to substance 15033463
D013481 Superoxides GSTM1 protein results in decreased susceptibility to Superoxidesdecreases response to substance 10661898
C003377 taxifolin taxifolin results in increased expression of GSTM1 mRNAincreases expression 17541156
D013662 Tea Tea inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased activity of GSTM1 protein]affects cotreatment|decreases activity|decreases reaction 12725062
C004648 testosterone enanthate testosterone enanthate affects the expression of GSTM1 mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of GSTM1 mRNAincreases expression 12377990
D013749 Tetrachlorodibenzodioxin NFE2L2 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTM1 mRNA]affects reaction|increases expression 19474220
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of GSTM1 mRNAaffects binding|increases expression 16214954
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of GSTM1 mRNAincreases expression 18172886
18796159
19474220
17949056
D013844 Thiazoles Thiazoles results in increased expression of GSTM1 mRNAincreases expression 8951341
D013844 Thiazoles Thiazoles results in increased expression of GSTM1 proteinincreases expression 8951341
D013853 Thioacetamide Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in decreased expression of GSTM1 protein]decreases expression|decreases reaction 12370186
D013853 Thioacetamide Thioacetamide results in decreased expression of GSTM1 proteindecreases expression 12370186
D013853 Thioacetamide Thioacetamide results in increased expression of GSTM1 mRNAincreases expression 15497818
D008063 Thioctic Acid [Dietary Fats co-treated with Thioctic Acid] results in increased expression of GSTM1 mRNAaffects cotreatment|increases expression 18367378
C082032 tocotrienol, alpha GSTM1 gene polymorphism affects the susceptibility to [Ascorbic Acid co-treated with tocotrienol, alpha]affects cotreatment|affects response to substance 15668500
D014050 Toluene GSTM1 gene polymorphism affects the susceptibility to Tolueneaffects response to substance 17292523
D014051 Toluene 2,4-Diisocyanate GSTM1 protein polymorphism results in increased susceptibility to Toluene 2,4-Diisocyanateincreases response to substance 11927838
D014212 Tretinoin Tretinoin metabolite results in decreased expression of GSTM1 mRNAdecreases expression 15982314
C032910 triadimefon triadimefon affects the expression of GSTM1 mRNAaffects expression 17383973
D014230 Triazoles Triazoles results in increased expression of GSTM1 mRNAincreases expression 8951341
C010360 triethyllead triethyllead results in increased expression of GSTM1 mRNAincreases expression 9020200
C052920 trimethylarsine oxide trimethylarsine oxide results in increased expression of GSTM1 mRNAincreases expression 16436460
C052920 trimethylarsine oxide trimethylarsine oxide results in increased expression of GSTM1 proteinincreases expression 16436460
D014303 Trinitrotoluene Trinitrotoluene affects the expression of GSTM1 mRNAaffects expression 21346803
C012594 triphenyltin chloride triphenyltin chloride inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]affects metabolic processing|decreases reaction 7733673
C012594 triphenyltin chloride triphenyltin chloride results in decreased activity of GSTM1 proteindecreases activity 7733673
D014315 Triterpenes Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of GSTM1 mRNA]increases expression|increases reaction 18544911
C057693 troglitazone GSTM1 gene polymorphism affects the susceptibility to troglitazoneaffects response to substance 12732844
D014750 Vincristine GSTM1 gene polymorphism affects the susceptibility to Vincristineaffects response to substance 15713801
D014750 Vincristine GSTM1 protein results in decreased susceptibility to Vincristinedecreases response to substance 15044619
D014750 Vincristine Sulfinpyrazone inhibits the reaction [GSTM1 protein results in decreased susceptibility to Vincristine]decreases reaction|decreases response to substance 15044619
D014752 Vinyl Chloride GSTM1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]affects mutagenesis|affects reaction 16097394
D014752 Vinyl Chloride [GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] results in increased susceptibility to Vinyl Chlorideaffects cotreatment|increases response to substance 16977343
D024483 Vitamin K 3 Vitamin K 3 results in increased expression of GSTM1 mRNAincreases expression 14610226
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 2-amino-4,6-dinitrotoluene 34.787525203
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 34.787525203
MESH:D000014 Abnormalities, Drug-Induced Carbamazepine 34.788986270
MESH:D000014 Abnormalities, Drug-Induced Ethanol 34.7818926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Isotretinoin 34.7818769834
MESH:D000014 Abnormalities, Drug-Induced Methotrexate 34.7812039119
MESH:D000014 Abnormalities, Drug-Induced methylmercuric chloride 34.786734493
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 34.786195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 34.7815322242 14514962 11752688
MESH:D000014 Abnormalities, Drug-Induced Trinitrotoluene 34.787525203
MESH:D000015 Abnormalities, Multiple Isotretinoin 3.8618769834
MESH:D000138 Acidosis Ammonium Chloride 6.4718287403
MESH:D000138 Acidosis Ethanol 6.4711192467
MESH:D017486 Acneiform Eruptions Isotretinoin 5.0416232082
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 7.9217505938
MESH:D000152 Acne Vulgaris Isotretinoin 7.9216185265 18769834
MESH:D058186 Acute Kidney Injury Cisplatin 8.4712690470 15814532 17670903
MESH:D058186 Acute Kidney Injury Mercuric Chloride 8.4711274264
MESH:D058186 Acute Kidney Injury Superoxides 8.4718460982
MESH:D055371 Acute Lung Injury pirinixic acid 2.0018653653
MESH:D000230 Adenocarcinoma arsenic trioxide 12.4711798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 12.4720127859 20464547
MESH:D000230 Adenocarcinoma Cisplatin 12.4717638652 11798837
MESH:D000230 Adenocarcinoma Doxorubicin 12.4717418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 12.4714692618
MESH:D000230 Adenocarcinoma Indomethacin 12.4716537180
MESH:D000230 Adenocarcinoma Vincristine 12.4719825857
MESH:D000236 Adenoma 2-Acetylaminofluorene 18.4710737359
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 18.473712494
MESH:D000236 Adenoma Benzo(a)pyrene 18.476695378
MESH:D000236 Adenoma beta-Naphthoflavone 18.4719389873
MESH:D000236 Adenoma Diethylnitrosamine 18.4710737359 6695378
MESH:D000236 Adenoma Indomethacin 18.4711497255
MESH:D000236 Adenoma Melatonin 18.4717195641
MESH:D002759 Adenoma, Bile Duct 2-Acetylaminofluorene 4.776705139
MESH:D018248 Adenoma, Liver Cell dicyclanil 20.0917162532
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 20.0919052882 18056438 17620307 17162532 19061943 16434500
MESH:D018248 Adenoma, Liver Cell Phenobarbital 20.0917620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 20.0916434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 20.0916835633
MESH:D011125 Adenomatous Polyposis Coli dibenzoylmethane 7.1517942926
MESH:D011125 Adenomatous Polyposis Coli sulforafan 7.1517942926
MESH:D018246 Adrenocortical Adenoma Arsenic 3.9717306315
MESH:D000380 Agranulocytosis Clozapine 3.8616160616 12649775 14617031
MESH:D000382 Agricultural Workers' Diseases Chlorpyrifos 10.8711874814 17119214 16611668
MESH:D000382 Agricultural Workers' Diseases Diazinon 10.8716487989
MESH:D000382 Agricultural Workers' Diseases Paraquat 10.8711874814
MESH:D000382 Agricultural Workers' Diseases Pesticides 10.8717119214
MESH:D000419 Albuminuria Doxorubicin 3.3721441931
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.0815451039 15451040
OMIM:607154 ALLERGIC RHINITIS 4,4'-diphenylmethane diisocyanate 4.817973495
MESH:D000505 Alopecia Tretinoin 2.5815955085
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 4.4316640825
MESH:D016301 Alveolar Bone Loss Indomethacin 4.1317225004
MESH:D000544 Alzheimer Disease Indomethacin 5.3517627676 15579461
MESH:D000544 Alzheimer Disease Iron 5.3516563566 16640825
MESH:D000544 Alzheimer Disease Ozone 5.3515513908
MESH:D000544 Alzheimer Disease Plant Extracts 5.3516962711
MESH:D000690 Amyotrophic Lateral Sclerosis 4-hydroxy-2-nonenal 3.2110965797
MESH:D000740 Anemia 4-chloronitrobenzene 8.893710033
MESH:D000740 Anemia Iron 8.8916434484 16566752
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.8911748828
MESH:D000741 Anemia, Aplastic Benzene 3.3411369114 14761424 17661222
MESH:D018798 Anemia, Iron-Deficiency Iron 3.5517147795 17162259 17163184 16569441 17375513
MESH:D000756 Anemia, Sideroblastic Iron 7.5216910769
MESH:D000756 Anemia, Sideroblastic Superoxides 7.5216910769
MESH:D000799 Angioedema Acetaminophen 2.6110982225
MESH:D000853 Anophthalmos Ethanol 3.6315513904
MESH:D001008 Anxiety Disorders Ethanol 2.9811141031
MESH:D001014 Aortic Aneurysm Indomethacin 3.6810231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 7.7619183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 7.7610388637
MESH:D001145 Arrhythmias, Cardiac Iron 6.1116604332
MESH:D001145 Arrhythmias, Cardiac Quinidine 6.1118724381 18057881
MESH:D020261 Arsenic Poisoning Arsenic 2.3616835338 12569548 18414634 16251483
MESH:D001161 Arteriosclerosis Dietary Fats 5.9815238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 5.9811256880
MESH:D018771 Arthralgia Indomethacin 3.932160914
MESH:D001169 Arthritis, Experimental Dexamethasone 10.1717659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 10.1715885639
MESH:D001169 Arthritis, Experimental Plant Extracts 10.1714686799
MESH:D001169 Arthritis, Experimental Tretinoin 10.1716412693
MESH:D001172 Arthritis, Rheumatoid Indomethacin 6.3011248219
MESH:D001172 Arthritis, Rheumatoid Methotrexate 6.3017286800
MESH:D001172 Arthritis, Rheumatoid Ozone 6.3015570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 6.3016292516
MESH:D001249 Asthma marker/mechanism 16870661 18988661
MESH:D001249 Asthma 1,6-hexamethylene diisocyanate 10.9410934080
MESH:D001249 Asthma 4,4'-diphenylmethane diisocyanate 10.9411077012 15891530 10934080 6091945 10797510 8156442
MESH:D001249 Asthma Mustard Gas 10.9410378619
MESH:D001249 Asthma Ozone 10.9417854713 16373670
MESH:D001249 Asthma Toluene 2,4-Diisocyanate 10.947684630 6091945 12684321 15855793 170078 12762349 15590890 11077013 3040596 16210060 18394133 10934080 19187332 10797510 15590891 16792590 11467998 20032816 17015710 12585506 11742282 8156442 6091946
MESH:D001249 Asthma Tretinoin 10.9416456186
MESH:D001260 Ataxia Telangiectasia Iron 4.2315336622
MESH:D050197 Atherosclerosis Arsenic 11.4112928151 19371607
MESH:D050197 Atherosclerosis Asbestos 11.4118795166
MESH:D050197 Atherosclerosis Carbon Disulfide 11.4110658303 10367350
MESH:D050197 Atherosclerosis Iron 11.4116640825 16632123
MESH:D050197 Atherosclerosis Lipid Peroxides 11.4116632123
MESH:D001289 Attention Deficit Disorder with Hyperactivity Fatty Acids, Omega-3 6.2418448859
MESH:D001289 Attention Deficit Disorder with Hyperactivity Pesticides 6.2420478945
MESH:D001321 Autistic Disorder marker/mechanism 16472391
MESH:D001321 Autistic Disorder Acetaminophen 4.2818445737
MESH:D001321 Autistic Disorder Cysteine 4.2819056591 16917939 19267885
MESH:D001321 Autistic Disorder Fatty Acids, Omega-3 4.2816920077
MESH:D001321 Autistic Disorder Glutathione 4.2819056591 16917939 19267885 18929414
MESH:D001321 Autistic Disorder Haloperidol 4.2819368416 18080171
MESH:D001321 Autistic Disorder Iron 4.2817352947
MESH:D001321 Autistic Disorder Melatonin 4.2816897403 16919138
MESH:D001321 Autistic Disorder Pesticides 4.2817938740
MESH:D001327 Autoimmune Diseases sulforafan 4.3919761891
MESH:D001424 Bacterial Infections Iron 3.9816640825
MESH:D001471 Barrett Esophagus Tretinoin 3.2316935849
MESH:D001477 Bartter Syndrome Indomethacin 3.7910684365
MESH:D001607 Berylliosis Prednisone 4.5118757698
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 3.7811289319 1440618
MESH:D001661 Biliary Tract Neoplasms Vinyl Chloride 5.6211024202
MESH:D001714 Bipolar Disorder Carbamazepine 3.3517594078 20046352
MESH:D001768 Blister Mustard Gas 3.9419167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 17.1316206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 17.1319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 17.1312125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 17.1319483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 17.1316206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.5615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 1.8515746008
MESH:D001855 Bone Marrow Diseases Benzene 4.0016183116
MESH:D019046 Bone Marrow Neoplasms Cisplatin 13.3114601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 13.3114601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 13.3114601052
MESH:D001859 Bone Neoplasms Paclitaxel 3.4315867366
MESH:D001929 Brain Edema Indomethacin 3.7911481608
MESH:D002545 Brain Ischemia Indomethacin 6.5312524144
MESH:D002545 Brain Ischemia Plant Extracts 6.5316041641
MESH:D001932 Brain Neoplasms 1,3-butadiene 8.8016860786
MESH:D001932 Brain Neoplasms Doxorubicin 8.8017150277
MESH:D001932 Brain Neoplasms Vinyl Chloride 8.8012562636
MESH:D001943 Breast Neoplasms 1,3-butadiene 21.1312165863 11921183
MESH:D001943 Breast Neoplasms 2,4-diaminotoluene 21.1311921183
MESH:D001943 Breast Neoplasms alitretinoin 21.1316344269
MESH:D001943 Breast Neoplasms allyl sulfide 21.1317125941
MESH:D001943 Breast Neoplasms Ascorbic Acid 21.1316443354
MESH:D001943 Breast Neoplasms Benzene 21.1311921183 17162533
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 21.1320146248 17474063
MESH:D001943 Breast Neoplasms Cacodylic Acid 21.1317474063
MESH:D001943 Breast Neoplasms Cisplatin 21.1319526202 18382427
MESH:D001943 Breast Neoplasms Dietary Fats 21.1320435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 21.1317474063
MESH:D001943 Breast Neoplasms Doxorubicin 21.1316096432 17426702 18695136 15567936 15939500 15668708 18628466 16935488 16264153 17983394 15136595 11325840 19526202 18234424 16826403 15634643 17369602 15993339 18382427 15692762 15994142 16322301 16115903 16595493
MESH:D001943 Breast Neoplasms Estrogens, Catechol 21.1317261777
MESH:D001943 Breast Neoplasms Etoposide 21.1316322251
MESH:D001943 Breast Neoplasms Hexachlorobenzene 21.1312709520 15061365
MESH:D001943 Breast Neoplasms indole-3-carbinol 21.1316082211
MESH:D001943 Breast Neoplasms Indomethacin 21.1317401462
MESH:D001943 Breast Neoplasms Methotrexate 21.1316978400
MESH:D001943 Breast Neoplasms methyleugenol 21.1311921183
MESH:D001943 Breast Neoplasms Paclitaxel 21.1318234424 16244791 18223236 15136595 11325840 16273361 16115903 18323546
MESH:D001943 Breast Neoplasms Styrene 21.1315986119
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 21.1320435547
MESH:D001943 Breast Neoplasms Toluene 2,4-Diisocyanate 21.1311921183
MESH:D001943 Breast Neoplasms Tretinoin 21.1316873071 16443354 16166294
MESH:D016535 Bronchial Hyperreactivity 4,4'-diphenylmethane diisocyanate 8.588156442
MESH:D016535 Bronchial Hyperreactivity Ozone 8.5818315731 17626835 18417511 19059883 15516495 16777450 14754758
MESH:D016535 Bronchial Hyperreactivity Toluene 2,4-Diisocyanate 8.5815590891 8156442 12507178
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 3.9415286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 3.7417687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.3716813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.1811589617
MESH:D002056 Burns Ethanol 7.4316374292
MESH:D002056 Burns Indomethacin 7.4310459503
MESH:D002057 Burns, Chemical Plant Extracts 4.109625245
MESH:D002100 Cachexia Indomethacin 8.3715141370 16537180 11239499 15625704
MESH:D002100 Cachexia Ozone 8.3716183385
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 6.5216227642 18705752 15673190 16011737 15721981 3786805 15700767 16050911 10355542 16192424 16097048 16124888
MESH:D002252 Carbon Tetrachloride Poisoning Melatonin 6.5215700767
MESH:D002276 Carcinoid Tumor Doxorubicin 3.5816051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 1.7916835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 2.7517687452 15504454
MESH:D018236 Carcinoma, Embryonal Tretinoin 3.9216168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 42.3016705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 42.3016705839
MESH:D006528 Carcinoma, Hepatocellular 2-Acetylaminofluorene 42.3017761372 3581430 6705139 3084413 10737359
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 42.303581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 42.303084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 42.3017306315 16507464
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 42.3015073043 16217749 11135700 14691202 15553829
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 42.3018788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 42.3017982673
MESH:D006528 Carcinoma, Hepatocellular dicyclanil 42.3017162532
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 42.3019822196 17138121 20007298 19539802 10737359 17761372 18665156 10672840 16830150 18210153 20935162 3084413 16807293 17978847 19519916 16288022 18494052 19919837 17162532 18506893 18978308 16935385 21159647 20214788 19418558 19171122 18056438 19052882 20512989 20727157 19394651 16569478 20084675 17055752 19335982 19701751 20524982 19208518 16540662 18393292 16698587 17173139 18971187 16328049 18691550 18788625 16681979 20514400 11831363 16502159 20432363 19383236 3581430 19107877 17428255 16878318 20101231 18785209 16779866
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 42.3018059187 17876044 16234567 16023760
MESH:D006528 Carcinoma, Hepatocellular Ethanol 42.3015289165 15763234 18788625
MESH:D006528 Carcinoma, Hepatocellular Ethoxyquin 42.303084413
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 42.3016391822
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 42.3016313753
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 42.3020935162 20007298 6705139 1701930 17173139
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 42.3018834353
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 42.3017997003
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 42.301917145
MESH:D006528 Carcinoma, Hepatocellular Vinyl Chloride 42.3012958735 10699891 12828392 15289165
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 3.5211053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.1311352223 14736730 18791128
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.4716685392 12023789
MESH:D002291 Carcinoma, Papillary arsenic trioxide 3.6419014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 9.077296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 9.071485588 16201981
MESH:D002292 Carcinoma, Renal Cell Indomethacin 9.0717341418
MESH:D002292 Carcinoma, Renal Cell Vincristine 9.0716201981
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.0112490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 18.3918922899 17687452 15504454
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 18.3920419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 18.3917066447 18337622 6189445
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 18.396189445
MESH:D002294 Carcinoma, Squamous Cell Glutathione 18.3917015178
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 18.3912636206 15482327
MESH:D002294 Carcinoma, Squamous Cell Isotretinoin 18.3911237771
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 18.3916051514 16096774
MESH:D002294 Carcinoma, Squamous Cell Vincristine 18.396189445
MESH:D002295 Carcinoma, Transitional Cell Arsenic 2.9918640142
MESH:D006332 Cardiomegaly Ethanol 6.6119332462
MESH:D006332 Cardiomegaly Plant Extracts 6.6117645561
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.6118850075 18670907 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 7.8917007740 17519947 17924179 16109756 15811867 18627295 16278810 15505089 17974986 17131338 16952015 17308081 16242529 16651473 17928571 16364871 16455267 16731534 16612575 15476868 15792986 17329180 16269455 17351982 17382496
MESH:D009202 Cardiomyopathies Iron 7.8916640825
MESH:D009202 Cardiomyopathies pimagedine 7.8916612575
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 4.0617334414 16243910
MESH:D002311 Cardiomyopathy, Dilated Iron 4.0616604332
MESH:D002318 Cardiovascular Diseases Arsenic 4.4415738583 17938729 19152805
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 4.4416936243
MESH:D002340 Carotid Artery Diseases Arsenic 3.2316973168 18022660
MESH:D002375 Catalepsy Haloperidol 3.701977408 15215559
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 13.9714694615
MESH:D002386 Cataract Acetaminophen 13.9710977129
MESH:D002386 Cataract pimagedine 13.9717936468 15003327
MESH:D002386 Cataract Tretinoin 13.9717460283
MESH:D002386 Cataract Trinitrotoluene 13.9714694615 15817613
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 11.136135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 11.137505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.1320889678
MESH:D002471 Cell Transformation, Neoplastic Cytarabine 11.138243401
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 11.132727394 17174075 7505956 21159647
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.064080065
MESH:D002547 Cerebral Palsy Toluene 4.639294310
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.3716129372
MESH:D054506 Chloracne marker/mechanism 17101203
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.8919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.8916835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 9.8918291259
MESH:D002764 Cholecystitis Indomethacin 3.9311181007
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 7.6119486331 9022650
MESH:D002779 Cholestasis Ethinyl Estradiol 7.6111677210 17681005 17110522 16105132 15861022 16919318 17333356
MESH:D002779 Cholestasis pirinixic acid 7.6119176532
MESH:D002822 Choriocarcinoma Tretinoin 3.9216461808
MESH:D016770 Ciliophora Infections Quinine 4.5712113305
MESH:D002971 Cleft Lip Ethanol 2.7815513904
MESH:D002972 Cleft Palate Ethanol 10.9215513904
MESH:D002972 Cleft Palate Fluconazole 10.9216781842
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 10.9215340226 12621046 8697196 16354765 15668235
MESH:D002972 Cleft Palate Tretinoin 10.929407595
MESH:D002972 Cleft Palate triadimefon 10.9216781842
MESH:D003072 Cognition Disorders Clozapine 3.7717123785
MESH:D003092 Colitis Tretinoin 2.5417035595
MESH:D003093 Colitis, Ulcerative Dinitrochlorobenzene 4.4917373747 19159591
MESH:D003093 Colitis, Ulcerative phenethyl isothiocyanate 4.4920423518
MESH:D003110 Colonic Neoplasms arsenite 4.7415037631
MESH:D003110 Colonic Neoplasms Dexamethasone 4.7415824018
MESH:D003110 Colonic Neoplasms Indomethacin 4.7415936596 15963497 11260862 15786552 15637740 15625704
MESH:D003110 Colonic Neoplasms Iron 4.7416640825
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.7420501625
MESH:D015179 Colorectal Neoplasms Cisplatin 3.7415273666
MESH:D015179 Colorectal Neoplasms Doxorubicin 3.7418259882 18802399
MESH:D015179 Colorectal Neoplasms Indomethacin 3.7412606626 11197048 18059344 17054584
MESH:D015179 Colorectal Neoplasms Paclitaxel 3.7418802399
MESH:D003139 Common Cold Ascorbic Acid 4.2417323712
MESH:D000013 Congenital Abnormalities 2-amino-4,6-dinitrotoluene 13.4815095906
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 13.4815095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 13.4814669216 17141729
MESH:D000013 Congenital Abnormalities Trinitrotoluene 13.4815095906
MESH:D003233 Conjunctivitis, Allergic 4,4'-diphenylmethane diisocyanate 5.207973495
MESH:D023903 Coronary Restenosis arsenic trioxide 3.0212609071
MESH:D003328 Coronary Thrombosis methyleugenol 4.6016048847
MESH:D018352 Coronavirus Infections Indomethacin 4.4817302372
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 16.5510525206
MESH:D019465 Craniofacial Abnormalities Benzene 16.5515643154
MESH:D019465 Craniofacial Abnormalities Carbamazepine 16.559014606
MESH:D019465 Craniofacial Abnormalities Dexamethasone 16.5517728286
MESH:D019465 Craniofacial Abnormalities Ethanol 16.5511873399 19302082 10194807 15451039 15451040 15513904 11198716
MESH:D019465 Craniofacial Abnormalities Isotretinoin 16.5518769834 9879862
MESH:D019465 Craniofacial Abnormalities lead acetate 16.5519769572
MESH:D019465 Craniofacial Abnormalities Methotrexate 16.559562676 12039119
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 16.5515322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Toluene 16.559294310
MESH:D019465 Craniofacial Abnormalities Tretinoin 16.559142499 10589399 9664655 17551590 9211117 14991402 9125849 16925845 8800419 9224671
MESH:D019465 Craniofacial Abnormalities triadimefon 16.5516875885 15834900
MESH:D003490 Cyanosis 2,4-dinitrotoluene 11.9618551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 11.9618551238
MESH:D003490 Cyanosis Trinitrotoluene 11.9618551238
MESH:D003550 Cystic Fibrosis Glutathione 5.5619747007
MESH:D003550 Cystic Fibrosis Methotrexate 5.5619747007
MESH:D003643 Death Toluene 4.436431079
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 7.1215213294
MESH:D016757 Death, Sudden, Cardiac Haloperidol 7.1220210726
MESH:D003704 Dementia Haloperidol 3.4711575062
MESH:D003872 Dermatitis Benzene 3.5815902427
MESH:D017449 Dermatitis, Allergic Contact 1,6-hexamethylene diisocyanate 12.4218759878
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 12.4214531868 11298694 11906362 8970840 18759878 8156756 2524372 12868966
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diphenylmethane diisocyanate 12.4218759878 12868966
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 12.4212438553
MESH:D017449 Dermatitis, Allergic Contact Dinitrochlorobenzene 12.4215491423
MESH:D017449 Dermatitis, Allergic Contact Toluene 2,4-Diisocyanate 12.4218759878 12956900 15491423
MESH:D003876 Dermatitis, Atopic pirinixic acid 1.6918249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 5.833621924 2952479
MESH:D003877 Dermatitis, Contact Toluene 2,4-Diisocyanate 5.8317010967
MESH:D009783 Dermatitis, Occupational Vinyl Chloride 4.5010870345
MESH:D003882 Dermatomyositis Methotrexate 3.9520191521
MESH:D003920 Diabetes Mellitus Iron 3.3916640825 16604332
MESH:D003921 Diabetes Mellitus, Experimental triphenyltin chloride 4.459202216
MESH:D003922 Diabetes Mellitus, Type 1 Iron 2.8216506275
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 10.2416506275
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 10.2416402076
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 10.2420387270
MESH:D003924 Diabetes Mellitus, Type 2 Iron 10.2416506275
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 10.2417107852
MESH:D003924 Diabetes Mellitus, Type 2 troglitazone 10.2416023994
MESH:D003925 Diabetic Angiopathies troglitazone 4.4512601628
MESH:D003928 Diabetic Nephropathies Plant Extracts 3.3519706694
MESH:D003967 Diarrhea Dexamethasone 4.537237001
MESH:D003967 Diarrhea Indomethacin 4.537907874 7237001
MESH:D006970 Disorders of Excessive Somnolence Clozapine 4.3215331141
OMIM:607208 DRAVET SYNDROME Carbamazepine 4.2511748493
MESH:D004342 Drug Hypersensitivity marker/mechanism 20485159
MESH:D004342 Drug Hypersensitivity Carbamazepine 3.5216538176 15057820 20216337 16538175
MESH:D056486 Drug-Induced Liver Injury marker/mechanism 17465707
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 58.3721346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 58.3718551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2-amino-4,6-dinitrotoluene 58.3721346803
MESH:D056486 Drug-Induced Liver Injury 2-nitropropane 58.3715804453 16445897 20517888
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 58.3716192314 6679447 18289764 11289319 8291058 7440962 9653073 1440618 6482804 18692083 9022650 18648102 9328219
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 58.3721346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 58.3712392966 12958197 18713872 19739265 15619225 19085960 2444490 15968718 12153990 18071297 10774834 11287661 12594235 19416960 19923254 11834606 14550746 10915739 10663392 16081117 16485898 16227642 19370779 16109766 17562736 17522070 19420014 17906064 19164858 12705907 16393943 14986274 11739529 11421492 11529661 16177239 12540782 11461765 11743745 16781746 14725611
MESH:D056486 Drug-Induced Liver Injury allyl sulfide 58.3715950962
MESH:D056486 Drug-Induced Liver Injury bromobenzene 58.3710092053 12628495
MESH:D056486 Drug-Induced Liver Injury Carbamazepine 58.3717465707
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 58.3717522070 3786805 7440962 15998439 21278145 6623471 16227642 7120509 7179309 10092053 15027814 11566570 10915739 6884620 4309450 15968718 9327722 3732212 2869522 16177239 19085960 19336974
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 58.3717851650
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 58.3717654400
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 58.3719107877
MESH:D056486 Drug-Induced Liver Injury Diquat 58.3718164269 18445702
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 58.3717416283
MESH:D056486 Drug-Induced Liver Injury Ethanol 58.3711566570
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 58.3716221962
MESH:D056486 Drug-Induced Liver Injury pyrazole 58.3712499123
MESH:D056486 Drug-Induced Liver Injury Tea 58.3719370779
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 58.3720420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 58.3712963478
MESH:D056486 Drug-Induced Liver Injury Trinitrotoluene 58.3718551238 21346803
MESH:D056486 Drug-Induced Liver Injury troglitazone 58.3714986274
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 2.8619426721
MESH:D004362 Drug Toxicity Carbamazepine 11.5220216337
MESH:D004362 Drug Toxicity Cisplatin 11.5212231392 12649298 19839026 15033597
MESH:D004362 Drug Toxicity Doxorubicin 11.5218602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 11.5211462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 3.9318043480 16133044 18446180 12774134 16326151 17190690
MESH:D004381 Duodenal Ulcer Indomethacin 3.0017045617 17202747 17151854 17351913 17329845 10671773 11535926 11991626 11595431 16699067 11595415
MESH:D050171 Dyslipidemias Clozapine 5.5916402076
MESH:D050171 Dyslipidemias Dietary Fats 5.5918367378
MESH:D004417 Dyspnea Diazinon 3.5916487989
MESH:D004421 Dystonia Phenobarbital 2.861851702
MESH:C538011 Eales disease Ascorbic Acid 4.249068938
MESH:D004485 Eczema Dexamethasone 3.3012438553
MESH:D004487 Edema Dexamethasone 16.0919703484
MESH:D004487 Edema Indomethacin 16.098985016 16100529 10653021 7907874 8273558 7990266 19703484
MESH:D004487 Edema Mustard Gas 16.0911428647 9260866 11402378 11428631
MESH:D004487 Edema perfluorooctanoic acid 16.0912083418 17259670
MESH:D004487 Edema pirinixic acid 16.0912083418
MESH:D004487 Edema Plant Extracts 16.0912787963
MESH:D004487 Edema Tetrachlorodibenzodioxin 16.0911000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 7.8618230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 7.8618230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental 15-deoxy-delta(12,14)-prostaglandin J2 8.9916844232
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Carbamazepine 8.9917654737
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.9912538720
MESH:D018159 Endolymphatic Hydrops Dimethyl Sulfoxide 5.3220641076
MESH:D016889 Endometrial Neoplasms Doxorubicin 7.4217359293
MESH:D016889 Endometrial Neoplasms Estrogens, Catechol 7.4218566989
MESH:D016889 Endometrial Neoplasms Tretinoin 7.4216569247
MESH:D004715 Endometriosis Indomethacin 5.4415652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 5.449294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 9.9718037988
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 9.9715268973
MESH:D019446 Endotoxemia Indomethacin 3.3018509659
MESH:D004751 Enteritis Indomethacin 3.5210567023 16328016 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 3.7917980183
MESH:D004802 Eosinophilia 4,4'-diphenylmethane diisocyanate 11.748156442
MESH:D004802 Eosinophilia Indomethacin 11.7411298111
MESH:D004802 Eosinophilia Prednisone 11.7416111148
MESH:D004802 Eosinophilia Toluene 2,4-Diisocyanate 11.748156442
MESH:D004816 Epidermal Necrolysis, Toxic Carbamazepine 4.0919915237 18855540 16538176 20485159 16415921
MESH:D004831 Epilepsies, Myoclonic Carbamazepine 7.2417275665
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 7.243659116
MESH:D004828 Epilepsies, Partial Carbamazepine 6.3215008574 16628512 17116037
MESH:D004828 Epilepsies, Partial Phenobarbital 6.3211558140 3922381
MESH:D004827 Epilepsy Carbamazepine 6.5517178248 19439326 18234410 17465707 7988514 821787 20417680 19700373 19620853 9014606
MESH:D004827 Epilepsy Phenobarbital 6.5520417680
MESH:D004827 Epilepsy Plant Extracts 6.5519700373 19439326
MESH:D004832 Epilepsy, Absence Phenobarbital 2.486401628
MESH:D017029 Epilepsy, Complex Partial Carbamazepine 7.747750514
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 7.747750514
MESH:D004830 Epilepsy, Tonic-Clonic Carbamazepine 6.873659116 15276670
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 6.873659116
MESH:D004890 Erythema Mustard Gas 3.949357497
MESH:D004916 Erythromelalgia Carbamazepine 4.5019549232
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 3.8816302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 15.433581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 15.4320426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 15.4312903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 15.4316530937
MESH:D004938 Esophageal Neoplasms Cisplatin 15.4316785472 15464296 16481741 15173087 17638652
MESH:D004938 Esophageal Neoplasms Ethanol 15.4316704527
MESH:D004938 Esophageal Neoplasms Indomethacin 15.4311005569
MESH:D004938 Esophageal Neoplasms Paclitaxel 15.4316481741
MESH:D005076 Exanthema Carbamazepine 4.2520485159
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 5.4911564622
MESH:D005124 Eye Abnormalities Tretinoin 5.499664655 16938888
MESH:D005128 Eye Diseases Toluene 2,4-Diisocyanate 4.5318447907
MESH:D005218 Fat Necrosis Thioacetamide 4.4816456712
MESH:D005234 Fatty Liver arsenic trioxide 36.6215073043
MESH:D005234 Fatty Liver arsenite 36.6218296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 36.6212795759 17595544 12631006 61145 15959796 16045604 16239168 19224547
MESH:D005234 Fatty Liver Dietary Fats 36.6218296743 17967931 19551842 19004024
MESH:D005234 Fatty Liver Diethylnitrosamine 36.6220387270 21071580
MESH:D005234 Fatty Liver Ethanol 36.6218620774 19236843 16409862
MESH:D005234 Fatty Liver Ethinyl Estradiol 36.6215345470
MESH:D005234 Fatty Liver Iron 36.6216640825
MESH:D005234 Fatty Liver pirinixic acid 36.6220131406 19236843
MESH:D005234 Fatty Liver Plant Extracts 36.6215975614
MESH:D005234 Fatty Liver Vinyl Chloride 36.6212197357
MESH:D005235 Fatty Liver, Alcoholic Ethanol 4.4317920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.0816946407 15513904 15451040 10194807
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.2711858732
MESH:D005317 Fetal Growth Retardation lead acetate 4.2219769572
MESH:D005334 Fever 4,4'-diphenylmethane diisocyanate 6.327973495
MESH:D005334 Fever Indomethacin 6.3217627676 11852909 10431976
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 3.786705139
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 3.3819069698
MESH:D005354 Fibrosarcoma Indomethacin 3.6810962813
MESH:D005355 Fibrosis arsenite 19.5018296743
MESH:D005355 Fibrosis Carbon Tetrachloride 19.5018705752
MESH:D005355 Fibrosis Dietary Fats 19.5018296743
MESH:D005355 Fibrosis Indomethacin 19.5017994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 19.5020067830
MESH:D005355 Fibrosis Tretinoin 19.5017994277
MESH:D005393 Fish Diseases Quinine 4.5412113305
MESH:D005499 Folliculitis Indomethacin 3.9311298111
MESH:D005534 Foot Diseases Arsenic 4.326392382
MESH:D005621 Friedreich Ataxia Iron 4.2316640825 16604332
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.0916904648
MESH:D005756 Gastritis Acetaminophen 23.2316983495
MESH:D005756 Gastritis Diquat 23.2315046732
MESH:D005756 Gastritis Ethanol 23.2315046732
MESH:D005756 Gastritis Indomethacin 23.2315046732
MESH:D005756 Gastritis Iodoacetamide 23.2315046732
MESH:D005909 Glioblastoma Doxorubicin 6.6317150277
MESH:D005909 Glioblastoma Indomethacin 6.6312870263
MESH:D005909 Glioblastoma Tretinoin 6.6317312396
MESH:D005910 Glioma 1,3-butadiene 4.5915814359
MESH:D005910 Glioma Indomethacin 4.5916487511 18371953
MESH:D005911 Gliosis Paraquat 3.9311124998
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.2411849393
MESH:D006030 Glycosuria, Renal Mercuric Chloride 4.702918855
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 2.897505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.3510696789
MESH:D006073 Gout Indomethacin 4.1311248219
MESH:D006086 Graft vs Host Disease Methotrexate 3.9516518429
MESH:D006258 Head and Neck Neoplasms Cisplatin 10.7415102660 15464296
MESH:D006258 Head and Neck Neoplasms Doxorubicin 10.7415692506
MESH:D006258 Head and Neck Neoplasms Indomethacin 10.7415482327
MESH:D006258 Head and Neck Neoplasms Tretinoin 10.7416096774
MESH:D034381 Hearing Loss Cisplatin 10.6219898482
MESH:D034381 Hearing Loss Dimethyl Sulfoxide 10.6220641076
MESH:D034381 Hearing Loss Styrene 10.6217420221
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 3.9216084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.3515464296
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 9.2116080930
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 9.2120471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.2110048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 9.2114991402 9664655
MESH:D006331 Heart Diseases Doxorubicin 2.5616244372 12587719 18006777 16707910 17875725 16144979 16330681 17888722 14766674 16244371 16879835 18674790 16495754
MESH:D006333 Heart Failure Doxorubicin 6.7117481944
MESH:D006333 Heart Failure pirinixic acid 6.7120558911
MESH:D006333 Heart Failure Plant Extracts 6.7118097624
MESH:D006390 Hemangioendothelioma 2-Acetylaminofluorene 9.016705139
MESH:D006390 Hemangioendothelioma Vinyl Chloride 9.0115380572
MESH:D006393 Hemangiopericytoma Vinyl Chloride 5.6210964802
MESH:D006394 Hemangiosarcoma 1,3-butadiene 12.7110930038 2208121
MESH:D006394 Hemangiosarcoma 2-Acetylaminofluorene 12.716705139
MESH:D006394 Hemangiosarcoma Doxorubicin 12.7115692506
MESH:D006394 Hemangiosarcoma Vinyl Chloride 12.7112958735 12762079 15999577 15989139 11217710 12828392 12211074
MESH:D006402 Hematologic Diseases Benzene 3.5116183116
MESH:D006432 Hemochromatosis Iron 3.5016604332 16640825 17255318 16574947 17236123 17053826
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.2211000095
MESH:D006486 Hemosiderosis 4-chloronitrobenzene 8.883710033
MESH:D006486 Hemosiderosis Iron 8.8816604332
MESH:D006501 Hepatic Encephalopathy Indomethacin 7.2015633222
MESH:D006501 Hepatic Encephalopathy Thioacetamide 7.2018665440 17276928 15929193
MESH:D006504 Hepatic Veno-Occlusive Disease Busulfan 5.9914986274
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 13.016705139
MESH:D006505 Hepatitis Carbon Tetrachloride 13.0119900420 19110552
MESH:D006505 Hepatitis Diazinon 13.0116487989
MESH:D006505 Hepatitis Thioacetamide 13.0116456712
MESH:D019698 Hepatitis C, Chronic Indomethacin 3.5115135802
MESH:D006521 Hepatitis, Chronic Methyldopa 5.4414986274
MESH:D006525 Hepatitis, Viral, Human allyl sulfide 9.5815950962
MESH:D006525 Hepatitis, Viral, Human Iron 9.5816640825
MESH:D006527 Hepatolenticular Degeneration Iron 3.7517182432
MESH:D006529 Hepatomegaly fumonisin B1 31.6616221962
MESH:D006529 Hepatomegaly Iron 31.6616890145
MESH:D006529 Hepatomegaly perfluorooctanoic acid 31.663609246
MESH:D006529 Hepatomegaly Phenobarbital 31.6616109766
MESH:D006529 Hepatomegaly pirinixic acid 31.6619176532 16221962 18467677 19772884
MESH:D006529 Hepatomegaly propiconazole 31.6617178688 17178689
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 31.6616120746 15340226 12621046
MESH:D006529 Hepatomegaly triadimefon 31.6617178688 17178689
MESH:D006529 Hepatomegaly Trinitrotoluene 31.6615817613
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 4.1116490937 16863852
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 4.117520565
MESH:D006561 Herpes Simplex Etoposide 6.2810809021
MESH:D006561 Herpes Simplex Plant Extracts 6.2810715843
MESH:D015658 HIV Infections Iron 4.4116597321
MESH:D015658 HIV Infections Plant Extracts 4.4112878215
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 4.5117440010
MESH:D006689 Hodgkin Disease Cisplatin 15.0516170182 16200630
MESH:D006689 Hodgkin Disease Cytarabine 15.0516200630
MESH:D006689 Hodgkin Disease Doxorubicin 15.0515147373 17606976 18501091
MESH:D006689 Hodgkin Disease Etoposide 15.0518180244 15147373 16135485 17606976 16200630
MESH:D006689 Hodgkin Disease Prednisone 15.0517606976 16135485 16794504
MESH:D006689 Hodgkin Disease Vincristine 15.0515147373 16135485 16794504 17606976
MESH:D019584 Hot Flashes Plant Extracts 3.5414716179 16566672 17454163
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 2.8116354765 15340226 16959395 8697196 18606429
MESH:D006930 Hyperalgesia Acetaminophen 13.7016870215
MESH:D006930 Hyperalgesia Ethanol 13.7018783367
MESH:D006930 Hyperalgesia Indomethacin 13.7012727271
MESH:D006930 Hyperalgesia perfluorooctanoic acid 13.7012083418
MESH:D006930 Hyperalgesia Tretinoin 13.7016870215
MESH:D034321 Hyperamylasemia Indomethacin 4.4817883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.3116899240
MESH:D006937 Hypercholesterolemia Dietary Fats 2.4921332399
MESH:D006940 Hyperemia Indomethacin 3.7912524144
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.3716778211
MESH:D006943 Hyperglycemia pirinixic acid 2.1020558911
MESH:D020138 Hyperhomocysteinemia Carbamazepine 9.6110459572
MESH:D020138 Hyperhomocysteinemia Plant Extracts 9.6116484555
MESH:D020138 Hyperhomocysteinemia Superoxides 9.6112615666
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 3.3517050553
MESH:D006948 Hyperkinesis Clozapine 7.8216046005
MESH:D006948 Hyperkinesis Methamphetamine 7.8217658665
MESH:D006949 Hyperlipidemias Dietary Fats 9.0221332399
MESH:D006949 Hyperlipidemias Indomethacin 9.0217546600
MESH:D006949 Hyperlipidemias Plant Extracts 9.0215975614 15268973
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 7.1815034207
MESH:D006965 Hyperplasia Carbamazepine 7.1818773962
MESH:D006967 Hypersensitivity Toluene 2,4-Diisocyanate 3.5310880147 11019492
MESH:D006973 Hypertension Arsenic 9.1816076760 9931084 11953799
MESH:D006973 Hypertension Benzene 9.1817940673
MESH:D006973 Hypertension Dexamethasone 9.1817042910
MESH:D006973 Hypertension Sodium, Dietary 9.1816870316
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 9.1818670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 2.9015338365
MESH:D006987 Hypesthesia Arsenic 4.3216093927
MESH:D007006 Hypogonadism Iron 3.4316640825
MESH:D007021 Hypospadias Ethinyl Estradiol 2.6216569931 16945680
MESH:D007022 Hypotension Dopamine 3.906740701
MESH:D007037 Hypothyroidism Iron 3.8916640825
MESH:D007077 Ileal Diseases Indomethacin 3.7910574470 18306037
MESH:D007079 Ileitis Indomethacin 4.1310647630 10651667 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.1316133044
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.3212013081
MESH:D007248 Infertility, Male Diazinon 11.3212948887 16466525
MESH:D007248 Infertility, Male Diquat 11.324850670
MESH:D007248 Infertility, Male Ethinyl Estradiol 11.3217937319
MESH:D007248 Infertility, Male Paraquat 11.324850670
MESH:D007248 Infertility, Male Trinitrotoluene 11.3212150543
MESH:D007249 Inflammation Benzoxazoles 25.742357250
MESH:D007249 Inflammation Dexamethasone 25.7411099482 8960868
MESH:D007249 Inflammation Dietary Fats 25.7420412841
MESH:D007249 Inflammation Diethylnitrosamine 25.7418785209
MESH:D007249 Inflammation Fatty Acids, Omega-3 25.7417296493
MESH:D007249 Inflammation Indomethacin 25.7412568917 3291741 7812673
MESH:D007249 Inflammation Metals 25.7416786165
MESH:D007249 Inflammation Mustard Gas 25.7411428620 11402378 9260866 16001271 17524151 11428647 9357497 11428631 8975870
MESH:D007249 Inflammation perfluorooctanoic acid 25.7412083418
MESH:D007249 Inflammation Plant Extracts 25.7419332304 12787963 16366677 15997105
MESH:D007249 Inflammation Prednisone 25.7416111148
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 25.7412200463 12878042
MESH:D007333 Insulin Resistance Dietary Fats 4.1818457598 11836018
MESH:D007333 Insulin Resistance pirinixic acid 4.1816306350
MESH:D007410 Intestinal Diseases Indomethacin 13.9311855677 17329856 18236018 11713966 10210152 15831440 15610444 17994277 11686837
MESH:D007410 Intestinal Diseases pimagedine 13.9311713966
MESH:D007410 Intestinal Diseases Superoxides 13.9310210152
MESH:D007410 Intestinal Diseases Tretinoin 13.9317994277
MESH:D007414 Intestinal Neoplasms Plant Extracts 3.5212351151 12584176 12628509
MESH:D019586 Intracranial Hypertension Indomethacin 4.1315241188
MESH:D019189 Iron Metabolism Disorders Iron 3.8917163184
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 3.789022650 8074119
MESH:D007569 Jaw Abnormalities Ethanol 15.5315513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 15.5316580747
MESH:D007569 Jaw Abnormalities Tretinoin 15.5315992940 17551590
MESH:D007569 Jaw Abnormalities triadimefon 15.5315992940 15834900
MESH:D007579 Jejunal Diseases Indomethacin 3.7910574470 16133968 18306037
MESH:D007642 Keratosis Arsenic 3.7716930632 12749816
MESH:D017492 Keratosis, Seborrheic alitretinoin 4.4216144296
MESH:D007673 Kidney Cortex Necrosis Cisplatin 3.9115464296
MESH:D007674 Kidney Diseases Acetaminophen 7.4815629191 12587719
MESH:D007674 Kidney Diseases Cisplatin 7.4812649298 15190930 18289764 12231392 19839026
MESH:D007674 Kidney Diseases Doxorubicin 7.4816775033 15699352 15369732
MESH:D007674 Kidney Diseases Indomethacin 7.4817190690
MESH:D007676 Kidney Failure, Chronic Doxorubicin 6.4016707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 6.4016518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 9.3516705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 9.3516705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 9.356582329
MESH:D007680 Kidney Neoplasms Vinyl Chloride 9.3512562636
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 3.5711231351
MESH:D007805 Language Development Disorders Methotrexate 3.959562676
MESH:D007859 Learning Disorders Ethanol 3.0515451040
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 2.8812228301 10320625 11703811
MESH:D007938 Leukemia marker/mechanism 14694614 18505952
MESH:D007938 Leukemia 1,3-butadiene 8.5016155477
MESH:D007938 Leukemia arsenic trioxide 8.5015070760
MESH:D007938 Leukemia Benzene 8.5014694614 18335105 15935818 17119257
MESH:D007938 Leukemia Tretinoin 8.5017143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 10.1416085563
MESH:D004915 Leukemia, Erythroblastic, Acute troglitazone 10.1416085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 2.6817077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.1016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 8.6114633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Busulfan 8.6110373061
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 8.6110785260 15631656 16572323
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.5919077051
MESH:D007951 Leukemia, Myeloid Benzene 9.5917506065
MESH:D007951 Leukemia, Myeloid Tretinoin 9.5916482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.1616467208 19850784 16968895 17050201 20471514
MESH:D015470 Leukemia, Myeloid, Acute Benzene 5.1619478238
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 5.1618360721
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 5.1616294345 17596541 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 7.3817339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.3815213294 16330433 17217047 16966277 19642359 19225113 19075265 12018890 9834237 16331271 17107899 15336539 17649720 15622746 11468182 15748426 19035177 12679006 12712474 11161223 16823087 17869043 17712046 16112521 16891316
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.3817506722 16788101 19225113 19075265 19029980 16823087 17301526 17294898 16140955 16766008 17217047 16891316 17368321 15748426 16935935 17339181 12679006 17107899 9834237 16331271 19642359 17649720 17712046 19035177 17361223
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.1816882451
MESH:D007964 Leukocytosis Indomethacin 4.1316537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 4.4817980183
MESH:D020961 Lewy Body Disease Iron 4.2316563566
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 4.018812269
MESH:D017880 Limb Deformities, Congenital Ethanol 5.0617676605
MESH:D017880 Limb Deformities, Congenital Tretinoin 5.069224671
MESH:D008064 Lipidoses Clozapine 3.0117567588
MESH:D008080 Liposarcoma Paclitaxel 3.6717353645
MESH:D008101 Liver Abscess, Amebic Indomethacin 4.4811479899
MESH:D008103 Liver Cirrhosis arsenite 29.5318296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 29.5316221502 16943688 17334410 11408273 17157831 17174718 11903743 21278145 16239168
MESH:D008103 Liver Cirrhosis Dietary Fats 29.5318296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 29.5318665156 19638242 20032147 18407596 18522880
MESH:D008103 Liver Cirrhosis Ethanol 29.5315289165
MESH:D008103 Liver Cirrhosis Iron 29.5316640825
MESH:D008103 Liver Cirrhosis Methotrexate 29.5314986274
MESH:D008103 Liver Cirrhosis Phenobarbital 29.5321047994
MESH:D008103 Liver Cirrhosis Plant Extracts 29.5317157831
MESH:D008103 Liver Cirrhosis Vinyl Chloride 29.5312958735 15354062 11679801 15289165 12499459
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 3.8818295389
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.2915034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental marker/mechanism 15650968
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 18.4113678700 12666154 12546737 17823541 18395914 18376398 12898905 14512876 17557913 15370692 15818738 15730626 18412020 16015684 16116963 17714472 18420326 18472332 15057751 12445418 17631135 16136751 16192424 15673190 18705752 16638106 12667390 16248980 14716833 18054572 17766677 17761835 11481614 17869086 12609069 15931870 12649538 18472094 18279442 12389079 16011737 12632514 18156304 17698563 17976157 17481882 18429990 15338365 12741479 15925388 18205269 17922224 18395095 14620537 17640975 17805973 15959796 17708605 12958196 18006644 12632512 14716496 15996030 18210741 18187930 14748882 15362042 18251166 15052691 17721639 18418968 14724832 10355542 17525996 16033810 15893842 17565644 18339082 12586293 20821823 17944888 15123356 15876570 18277467 18166357 18317297 18263696 15650968 18481824 12445421 16027843 16097048 17900296
MESH:D008106 Liver Cirrhosis, Experimental Cysteine 18.4115158331
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 18.4116718785
MESH:D008106 Liver Cirrhosis, Experimental Dimethyl Sulfoxide 18.4111682029
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 18.4116439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 18.4118166357
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 18.4118194892
MESH:D008106 Liver Cirrhosis, Experimental Melatonin 18.4115925388 16703270 15298665
MESH:D008106 Liver Cirrhosis, Experimental oltipraz 18.4116544323
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 18.4115474484
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 18.4115479170
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 18.4112878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 18.4112679928 18032466 11481614 16248980 15075984 15716488 12557150 16126171 18263696 17629604 15288473 18380797 10677585 17355460 15095483 18031379 17050028 18458672 12085344 15474484 12891558 18295389 16098781 17292413 12531686 15316131 16511523 11172339 15362042 15078482 18606216 11682029 14739098 15158331 17127702 16343077 15334695 15288472 18615449 16097051 18416461 16489207 15465738 18395095 12175628
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 18.4118397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 26.7712969438 16610002 19460945 12587719 19014921 11587558 19784758 16611625
MESH:D008107 Liver Diseases Arsenic 26.7711134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 26.7716246199 15720792 16964402 17285989 15830285
MESH:D008107 Liver Diseases Chlorpyrifos 26.7715991261
MESH:D008107 Liver Diseases Diethylnitrosamine 26.7717034775
MESH:D008107 Liver Diseases Fluconazole 26.7714966256
MESH:D008107 Liver Diseases Hemin 26.7717173083
MESH:D008107 Liver Diseases Phenobarbital 26.7719363144
MESH:D008107 Liver Diseases Plant Extracts 26.7717034775
MESH:D008107 Liver Diseases propiconazole 26.7719363144
MESH:D008107 Liver Diseases Thioacetamide 26.7718374380 15158337 16337175
MESH:D008107 Liver Diseases triadimefon 26.7719363144
MESH:D008107 Liver Diseases Vinyl Chloride 26.7715211785 16270392
MESH:D008108 Liver Diseases, Alcoholic Ethanol 7.5417207112 17347304
MESH:D008108 Liver Diseases, Alcoholic Iron 7.5417207112 16737972
MESH:D017093 Liver Failure Carbon Tetrachloride 2.9715123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.9116871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.9116899240 14706259
MESH:D017114 Liver Failure, Acute Thioacetamide 9.9115313186 12479984 15633222 17276928
MESH:D008113 Liver Neoplasms 1,3-butadiene 58.402208121
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 58.407678174
MESH:D008113 Liver Neoplasms 2-Acetylaminofluorene 58.4014678523 18001218 10737359 10672840 11376686 16273603
MESH:D008113 Liver Neoplasms Arsenic 58.4016368122
MESH:D008113 Liver Neoplasms arsenic trioxide 58.4014682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 58.4021137059 20195826
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 58.4019389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 58.4019294768
MESH:D008113 Liver Neoplasms ciprofibrate 58.4012771043
MESH:D008113 Liver Neoplasms dicyclanil 58.4020118626
MESH:D008113 Liver Neoplasms Diethylnitrosamine 58.4020501860 21047994 20118626 19090486 18978307 19833225 12112319 21071580 18644402 15885732 19294768 19255062 19638242 20434301 19426721 9163691 18648771 19427195 18977376 2422723 18754104 19551842 19690152 19850985 19499222 21167192 20101389 20137499 21278145 19996281 20452335 19073162 19254457 16942905 15175105 20405173 19812893 20583210 2862719 20492335 12771043 19256749 19642983 10737359
MESH:D008113 Liver Neoplasms Iron 58.4016640825 20302851
MESH:D008113 Liver Neoplasms oxfendazole 58.4018754104
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 58.4014757943 18709148
MESH:D008113 Liver Neoplasms Phenobarbital 58.4015975961 19812893 8742319 21047994 19482888 19073162
MESH:D008113 Liver Neoplasms Piperonyl Butoxide 58.4018648771 15890375 20101389 19690152
MESH:D008113 Liver Neoplasms pirinixic acid 58.4020007298 16377806 15890375
MESH:D008113 Liver Neoplasms Plant Extracts 58.4019168119
MESH:D008113 Liver Neoplasms propiconazole 58.4019028983
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 58.4016984957
MESH:D008113 Liver Neoplasms triadimefon 58.4019028983
MESH:D008113 Liver Neoplasms Vinyl Chloride 58.4012211074 12762079 11024202 10629081 11679801 10964802 15999577
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 57.262876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental 2-Acetylaminofluorene 57.261399818 6150874 534488
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 57.26598648 6587162 1399818 3712494
MESH:D008114 Liver Neoplasms, Experimental Aflatoxins 57.2615583823
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 57.2620377131
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 57.2618544905
MESH:D008114 Liver Neoplasms, Experimental Benzene 57.2612562636
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 57.2618164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 57.2612014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 57.2619004024 18775883 19519916 18079962 17942915 18544905 18308698 19009564 2563599 17174075 19126423 19539802 17854601 16267830 3124819 21159647 18093689 18253720 16842330 9362446 18164116 18282651
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 57.2616842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Hexachlorobenzene 57.261423854
MESH:D008114 Liver Neoplasms, Experimental kojic acid 57.2618544905
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 57.261399818 6150874 17172636 2563599 18308698
MESH:D008114 Liver Neoplasms, Experimental propiconazole 57.2617178689
MESH:D008114 Liver Neoplasms, Experimental styrene oxide 57.2612562636
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 57.2612151625
MESH:D008114 Liver Neoplasms, Experimental triadimefon 57.2617178689
MESH:D008114 Liver Neoplasms, Experimental Vinyl Chloride 57.2612562636
MESH:D008133 Long QT Syndrome arsenic trioxide 5.3415213294
MESH:D008133 Long QT Syndrome Quinidine 5.3411989578 15350150
MESH:D008171 Lung Diseases Ascorbic Acid 10.0116863852
MESH:D008171 Lung Diseases Fluconazole 10.0114966256
MESH:D008171 Lung Diseases Mustard Gas 10.0118161513 18702808
MESH:D008171 Lung Diseases Ozone 10.0119066396 8266340
MESH:D017563 Lung Diseases, Interstitial Benzene 7.5914698565
MESH:D017563 Lung Diseases, Interstitial Methotrexate 7.5918516814
MESH:D055370 Lung Injury naphthalene 5.736834280
MESH:D055370 Lung Injury Ozone 5.7320417186
MESH:D008175 Lung Neoplasms 1,3-butadiene 50.312208121 16860786 17372256
MESH:D008175 Lung Neoplasms 2-Acetylaminofluorene 50.3111376686
MESH:D008175 Lung Neoplasms 9-deoxy-delta-9-prostaglandin D2 50.3115899809
MESH:D008175 Lung Neoplasms alitretinoin 50.3116413115
MESH:D008175 Lung Neoplasms Arsenic 50.3117976673 17306315 19168569
MESH:D008175 Lung Neoplasms arsenic trioxide 50.3111798837 19825857
MESH:D008175 Lung Neoplasms arsenite 50.3116809336
MESH:D008175 Lung Neoplasms Asbestos 50.3112111688
MESH:D008175 Lung Neoplasms Ascorbic Acid 50.3116401635
MESH:D008175 Lung Neoplasms Benzene 50.3112562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 50.3117053015 18569708 6695378 20464547 20064080 18816296 20135361 18520028 20869020
MESH:D008175 Lung Neoplasms Cisplatin 50.3117225452 11798837 6189445
MESH:D008175 Lung Neoplasms Dexamethasone 50.3115824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 50.316695378 20970405 21163286 20512841
MESH:D008175 Lung Neoplasms Doxorubicin 50.3117418594 6189445
MESH:D008175 Lung Neoplasms Indomethacin 50.3111497255 11053908 16537180
MESH:D008175 Lung Neoplasms Iron 50.3116640825
MESH:D008175 Lung Neoplasms Isotretinoin 50.3115899809
MESH:D008175 Lung Neoplasms Melatonin 50.3117195641
MESH:D008175 Lung Neoplasms Mustard Gas 50.313148597 8781369
MESH:D008175 Lung Neoplasms Ozone 50.318597069 7614698
MESH:D008175 Lung Neoplasms Plant Extracts 50.3120869020
MESH:D008175 Lung Neoplasms Polycyclic Hydrocarbons, Aromatic 50.3110814675
MESH:D008175 Lung Neoplasms Styrene 50.3112562636
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 50.3111884234 19555203
MESH:D008175 Lung Neoplasms Vincristine 50.3119825857 6189445
MESH:D008175 Lung Neoplasms Vinyl Chloride 50.3112958735 12562636
MESH:D008180 Lupus Erythematosus, Systemic Carbamazepine 4.2616628512
MESH:D008180 Lupus Erythematosus, Systemic Melatonin 4.2616373423
MESH:D008223 Lymphoma 1,3-butadiene 16.7617941976 9205081 18798262 8764131 9488045 11980663 2208121
MESH:D008223 Lymphoma Benzene 16.7617584886 17119257
MESH:D008223 Lymphoma Chlorambucil 16.7610745627
MESH:D008223 Lymphoma Doxorubicin 16.7616098063
MESH:D008223 Lymphoma Etoposide 16.7612854902 12556972
MESH:D008223 Lymphoma Methotrexate 16.7617352296
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 5.4717654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 5.4714749477
MESH:D016399 Lymphoma, T-Cell Doxorubicin 3.3815621674
MESH:D008268 Macular Degeneration Iron 3.1516640825
MESH:D015674 Mammary Neoplasms, Animal 1,3-butadiene 14.342208121
MESH:D015674 Mammary Neoplasms, Animal Benzene 14.3412562636
MESH:D015674 Mammary Neoplasms, Animal Styrene 14.3412562636
MESH:D015674 Mammary Neoplasms, Animal Vinyl Chloride 14.3412562636
MESH:D008325 Mammary Neoplasms, Experimental 1,3-butadiene 9.3711921183
MESH:D008325 Mammary Neoplasms, Experimental 2,4-diaminotoluene 9.3711921183
MESH:D008325 Mammary Neoplasms, Experimental Benzene 9.3711921183
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 9.3715458769
MESH:D008325 Mammary Neoplasms, Experimental methyleugenol 9.3711921183
MESH:D008527 Medulloblastoma Tretinoin 2.1217453147
MESH:D008545 Melanoma Cisplatin 8.7512393984 16248763 18332650 17761969 12883367 18505091 18176117 15577323 11135225 12374674 16432458 17023156 16809738
MESH:D008545 Melanoma Dinitrochlorobenzene 8.7517334785 12202904
MESH:D008545 Melanoma Doxorubicin 8.7516827129
MESH:D008545 Melanoma Isotretinoin 8.7517237267
MESH:D008545 Melanoma Paclitaxel 8.7512025231 16342250 12040289
MESH:D008545 Melanoma Tretinoin 8.7516752155
MESH:D008545 Melanoma Vitamin K 3 8.7519082730
MESH:D018328 Melanoma, Amelanotic Cisplatin 8.0815990972
MESH:D018328 Melanoma, Amelanotic Vincristine 8.0815990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.3819513568
MESH:D008569 Memory Disorders Ethanol 3.0418411066 15451040
MESH:D008591 Meningomyelocele Tretinoin 3.2316940565
MESH:D001523 Mental Disorders Clozapine 4.5216856516
MESH:D001523 Mental Disorders Haloperidol 4.5216856516
MESH:D008607 Mental Retardation Carbamazepine 4.429014606
MESH:D008607 Mental Retardation Toluene 4.429294310
MESH:D008654 Mesothelioma marker/mechanism 17290392
MESH:D008654 Mesothelioma Asbestos 6.3318709470 16564556 18310086 16319530 16919927
MESH:D008654 Mesothelioma Cisplatin 6.3317638057
MESH:D008654 Mesothelioma Doxorubicin 6.3317638057
MESH:D024821 Metabolic Syndrome X Clozapine 3.3619142101
MESH:D008679 Metaplasia Ozone 3.8710496685
MESH:D008708 Methemoglobinemia 4-chloronitrobenzene 4.923710033
MESH:D008881 Migraine Disorders Indomethacin 2.7411903285
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.3715792986
MESH:D019957 Motor Skills Disorders Toluene 4.089294310
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 5.2816381670
MESH:D009062 Mouth Neoplasms Indomethacin 5.2812636206
MESH:D052016 Mucositis Doxorubicin 8.4917415656
MESH:D052016 Mucositis Methotrexate 8.4917488658
MESH:D009101 Multiple Myeloma arsenic trioxide 9.3915949261 11468182 14977855 19417148 19549372
MESH:D009101 Multiple Myeloma Benzene 9.3917119195
MESH:D009101 Multiple Myeloma Dexamethasone 9.3915867202 16118317 15744524
MESH:D009101 Multiple Myeloma Paclitaxel 9.3914749477
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 4.4317086897
MESH:D009135 Muscular Diseases pirinixic acid 2.3216239165
MESH:D009181 Mycoses Iron 4.2316640825
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.4418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.3316882451 16105982
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 7.339809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.3317596541
MESH:D009203 Myocardial Infarction Doxorubicin 5.4915857846 19429709
MESH:D009203 Myocardial Infarction pirinixic acid 5.4919151258
MESH:D009203 Myocardial Infarction Vincristine 5.4917284715
MESH:D017202 Myocardial Ischemia Arsenic 9.3515371236
MESH:D017202 Myocardial Ischemia Iron 9.3516604332
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 9.3512213967
MESH:D015428 Myocardial Reperfusion Injury Iron 5.2416604332
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 5.2416411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.2617484760
MESH:D009224 Myotonia Congenita Carbamazepine 8.7620399394
MESH:D009224 Myotonia Congenita Quinine 8.761896199
MESH:D009336 Necrosis 2,4-dinitrotoluene 20.7518551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 20.7518551238 7678174
MESH:D009336 Necrosis 2-nitropropane 20.7512195237
MESH:D009336 Necrosis Melatonin 20.7512195237
MESH:D009336 Necrosis Trinitrotoluene 20.7518551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 2.8016624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 10.433581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 10.439029167 3581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 10.4318259882
MESH:D009362 Neoplasm Metastasis Indomethacin 10.4316537180 11239499 11053908
MESH:D009362 Neoplasm Metastasis Paclitaxel 10.4315867366
MESH:D009369 Neoplasms alitretinoin 9.6916946489
MESH:D009369 Neoplasms Benzo(a)pyrene 9.6911141357
MESH:D009369 Neoplasms Cisplatin 9.6916773208
MESH:D009369 Neoplasms pirinixic acid 9.6917405874
MESH:D009369 Neoplasms Tretinoin 9.6916594593 16946489
MESH:D009369 Neoplasms Vinyl Chloride 9.6911911487
MESH:D009374 Neoplasms, Experimental 1,3-butadiene 8.949488045 9205081 8764131
MESH:D009374 Neoplasms, Experimental Indomethacin 8.9410663608 15625704
MESH:D009374 Neoplasms, Experimental Toluene 2,4-Diisocyanate 8.941670384
MESH:D016609 Neoplasms, Second Primary marker/mechanism 16703596
MESH:D009389 Neovascularization, Pathologic arsenite 3.2215738583
MESH:D009395 Nephritis, Interstitial Cisplatin 3.2815464296
MESH:D009401 Nephrosis Doxorubicin 3.5716899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 6.1715640375 16889571
MESH:D009404 Nephrotic Syndrome Iron 6.1717178036
MESH:D009410 Nerve Degeneration Paraquat 2.7216893418
MESH:D009422 Nervous System Diseases Carbon Disulfide 4.6610669001
MESH:D009421 Nervous System Malformations Carbamazepine 9.8116990009
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.8114600291
MESH:D009421 Nervous System Malformations Tretinoin 9.819125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 13.006679447
MESH:D009436 Neural Tube Defects Arsenic 13.0016620997
MESH:D009436 Neural Tube Defects arsenic trioxide 13.0010525206
MESH:D009436 Neural Tube Defects Benzene 13.0015643154
MESH:D009436 Neural Tube Defects Tretinoin 13.009142499
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 3.9917168769
MESH:D009447 Neuroblastoma 1,3-butadiene 9.6715814359
MESH:D009447 Neuroblastoma Cisplatin 9.678761367
MESH:D009447 Neuroblastoma Doxorubicin 9.6715555623
MESH:D009447 Neuroblastoma Isotretinoin 9.6717368321
MESH:D019636 Neurodegenerative Diseases Acetaminophen 11.5418514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 11.5420387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 11.5412349958
MESH:D019636 Neurodegenerative Diseases Iron 11.5417296847 16604332
MESH:D017599 Neuroectodermal Tumors Cisplatin 7.818761367
MESH:D017599 Neuroectodermal Tumors Vincristine 7.8112837982
MESH:D020078 Neurogenic Inflammation Arsenic 3.2317056641
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 3.8820387270
MESH:D020258 Neurotoxicity Syndromes Carbon Disulfide 8.4415315294
MESH:D020258 Neurotoxicity Syndromes Chlorpyrifos 8.4415081274
MESH:D020258 Neurotoxicity Syndromes Insecticides 8.4419861644
MESH:D009503 Neutropenia Mustard Gas 2.857688884 16761898
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 3.769802331
MESH:D009669 Nose Neoplasms Epichlorohydrin 5.554038687
MESH:D009765 Obesity Ascorbic Acid 8.4217217161
MESH:D009765 Obesity Clozapine 8.4218515891 19142110
MESH:D009765 Obesity Dietary Fats 8.4221332399 18674790 17217161 20132043 16723640 19632207 18457598 11836018 20518802
MESH:D009765 Obesity pirinixic acid 8.4220558911
MESH:D009765 Obesity Plant Extracts 8.4219056576 20132043
MESH:D007752 Obstetric Labor, Premature Indomethacin 3.936374098
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 35.7612819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 35.7616049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 35.766482804 4026338
MESH:D009784 Occupational Diseases 4,4'-diphenylmethane diisocyanate 35.768156442 6091945
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 35.7614694615
MESH:D009784 Occupational Diseases Benzene 35.7617119257 16737584 17178637 15935809 17479406 15727169 15576619 15913788 15612468
MESH:D009784 Occupational Diseases Toluene 2,4-Diisocyanate 35.763040596 18394133 6091946 11077013 6091945 12585506 8156442
MESH:D009784 Occupational Diseases Trinitrotoluene 35.7617852074 12819281 14694615
MESH:D009784 Occupational Diseases Vinyl Chloride 35.7612061072
MESH:D014009 Onychomycosis Fluconazole 5.1214966256
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 3.783988306
MESH:D010003 Osteoarthritis Indomethacin 5.037009135
MESH:D010003 Osteoarthritis Iron 5.0316640825
MESH:D010014 Osteolysis Paclitaxel 3.7715867366
MESH:D010018 Osteomalacia Carbamazepine 8.0717016548
MESH:D010018 Osteomalacia Phenobarbital 8.0717016548
MESH:D010024 Osteoporosis Iron 3.0016640825 16648989
MESH:D012516 Osteosarcoma Doxorubicin 3.0715930896
MESH:D010051 Ovarian Neoplasms 1,3-butadiene 13.472208121
MESH:D010051 Ovarian Neoplasms Arsenic 13.4717306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 13.4716624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms Benzene 13.4712562636
MESH:D010051 Ovarian Neoplasms Cisplatin 13.4719769630 6897625 15464296 17225452
MESH:D010051 Ovarian Neoplasms Paclitaxel 13.4711161223
MESH:D010051 Ovarian Neoplasms Tretinoin 13.4716936753
MESH:D010146 Pain Acetaminophen 10.4316870215
MESH:D010146 Pain Benzoxazoles 10.432357250
MESH:D010146 Pain Carbamazepine 10.4315215642
MESH:D010146 Pain Indomethacin 10.4317440234 13679232 17627676 3291741
MESH:D010146 Pain Tretinoin 10.4316870215
MESH:D010149 Pain, Postoperative Indomethacin 3.4618702446 12538197
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 14.6715580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 14.6719003803
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 14.6716540662
MESH:D010190 Pancreatic Neoplasms Ethanol 14.6712384795
MESH:D010190 Pancreatic Neoplasms Etoposide 14.6719003803
MESH:D010190 Pancreatic Neoplasms Phenobarbital 14.6716965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 14.6715976015
MESH:D010195 Pancreatitis Indomethacin 8.1915028970 17883296
MESH:D010195 Pancreatitis Insecticides 8.193421227 16258382
MESH:D010195 Pancreatitis Methyldopa 8.1910484002
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.5411578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 16.707296757
MESH:D010212 Papilloma cumene hydroperoxide 16.7012065085 17234724
MESH:D010212 Papilloma Hydrogen Peroxide 16.7012065085
MESH:D010212 Papilloma Iron 16.7012065085
MESH:D010212 Papilloma Plant Extracts 16.7015173996 16517061
MESH:D010235 Paraganglioma arsenic trioxide 3.0119927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 4.4816537180
MESH:D010267 Parapsoriasis Carbamazepine 4.5016538176
MESH:D020447 Parasomnias Iron 4.7817352947
MESH:D010300 Parkinson Disease Ditiocarb 7.0011445065
MESH:D010300 Parkinson Disease Eugenol 7.0017329831
MESH:D010300 Parkinson Disease Iron 7.0016640825 16563566
MESH:D010300 Parkinson Disease Paraquat 7.0016140633 12911755 15824117 15451049 11124998 11445065 11181820 16510128
MESH:D010302 Parkinson Disease, Secondary Paraquat 3.2416190885
MESH:D020734 Parkinsonian Disorders Carbon Disulfide 9.3615019297
MESH:D020734 Parkinsonian Disorders Indomethacin 9.3612349958
MESH:D020734 Parkinsonian Disorders Melatonin 9.3615574749
OMIM:167400 PAROXYSMAL EXTREME PAIN DISORDER Carbamazepine 4.7017679678 17145499
MESH:D051302 Paroxysmal Hemicrania Indomethacin 4.4811903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.0112520081
MESH:D010437 Peptic Ulcer Indomethacin 3.9311148446
MESH:D010518 Periodontitis Indomethacin 3.6817225004
MESH:D010523 Peripheral Nervous System Diseases Arsenic 6.2116093927
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 6.2115464296
MESH:D016491 Peripheral Vascular Diseases Arsenic 3.7716905509 6392382 15371236
MESH:D010538 Peritonitis Melatonin 6.6515707874
MESH:D010538 Peritonitis Ozone 6.6516369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 8.916228378
MESH:D010787 Photosensitivity Disorders 4-hydroxy-2-nonenal 8.9111550810
MESH:D003557 Phyllodes Tumor Doxorubicin 3.9217983394
MESH:D010900 Pituitary Diseases Iron 4.4316604332
MESH:D010997 Pleural Neoplasms Cisplatin 9.8417638057
MESH:D010997 Pleural Neoplasms Doxorubicin 9.8417638057
MESH:D011014 Pneumonia Ozone 7.0618929643 18007984 18381685
MESH:D011014 Pneumonia Paraquat 7.0612504350
MESH:D011041 Poisoning Diazinon 8.1317603234
MESH:D011041 Poisoning Iron 8.1316604332
MESH:D011041 Poisoning Mustard Gas 8.1315727166
MESH:D017285 Polymyositis Vinyl Chloride 5.6211642524
MESH:D017499 Porokeratosis alitretinoin 4.7616144296
MESH:D017119 Porphyria Cutanea Tarda Hexachlorobenzene 12.079918132
MESH:D017119 Porphyria Cutanea Tarda Iron 12.0716640825
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 12.0718163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 5.522563599
MESH:D011230 Precancerous Conditions Phenobarbital 5.522563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cytarabine 10.8021297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Daunorubicin 10.8021297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 10.8021297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Vincristine 10.8021297632
MESH:D011225 Pre-Eclampsia Iron 3.4116640825
MESH:D011248 Pregnancy Complications Carbamazepine 3.979014606
MESH:D047928 Premature Birth Indomethacin 3.9317000239
MESH:D011297 Prenatal Exposure Delayed Effects Carbamazepine 17.979014606
MESH:D011297 Prenatal Exposure Delayed Effects Isotretinoin 17.9718769834
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 17.9717132714
MESH:D011297 Prenatal Exposure Delayed Effects Pesticides 17.9717938740
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 17.9711399792 11222880 11896295 11118676
MESH:D011471 Prostatic Neoplasms marker/mechanism 11275366 18304461
MESH:D011471 Prostatic Neoplasms Arsenic 2.0816140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0819131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.0817292933
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.0816868541 16729912 15749863 18437689 16888761 15897917
MESH:D011471 Prostatic Neoplasms Estrogens, Catechol 2.0817261777
MESH:D011471 Prostatic Neoplasms Etoposide 2.0817172428
MESH:D011471 Prostatic Neoplasms Paclitaxel 2.0816356831 16729912 17136230 17172428
MESH:D011471 Prostatic Neoplasms Plant Extracts 2.0814666653 17804756
MESH:D011471 Prostatic Neoplasms Prednisone 2.0816888761
MESH:D011507 Proteinuria Arsenic 12.8421343184
MESH:D011507 Proteinuria Indomethacin 12.8411849393
MESH:D011507 Proteinuria Prednisone 12.8416636307
MESH:D011507 Proteinuria Tretinoin 12.8416636307
MESH:D011528 Protozoan Infections Iron 4.7816640825
MESH:D011537 Pruritus Ethinyl Estradiol 5.5515861022 16919318
MESH:D011537 Pruritus Mustard Gas 5.5518058305
MESH:D019310 Pseudolymphoma Carbamazepine 8.4912752131 9591791
MESH:D019310 Pseudolymphoma Phenobarbital 8.4912752131
MESH:D011565 Psoriasis Methotrexate 2.8417410198
MESH:D011595 Psychomotor Agitation Haloperidol 3.7711575062
MESH:D011596 Psychomotor Disorders Isotretinoin 4.7018769834
MESH:D011618 Psychotic Disorders Clozapine 5.8815331141
MESH:D011618 Psychotic Disorders Haloperidol 5.8811575062
MESH:D011625 Pterygium Tretinoin 3.5716723453
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 8.8114606601
MESH:D011657 Pulmonary Eosinophilia Toluene 2,4-Diisocyanate 8.8114606601
MESH:D011658 Pulmonary Fibrosis Mustard Gas 5.5017266442 17720292 17894541 10334151 17620002
MESH:D011658 Pulmonary Fibrosis Paraquat 5.5017997886 16324872
MESH:D011658 Pulmonary Fibrosis troglitazone 5.5018162602
MESH:D011928 Raynaud Disease marker/mechanism 16977343
MESH:D011928 Raynaud Disease Vinyl Chloride 4.9316977343
MESH:D000608 Renal Aminoacidurias Mercuric Chloride 4.872918855
MESH:D051437 Renal Insufficiency Cisplatin 10.4415464296
MESH:D051437 Renal Insufficiency Doxorubicin 10.4417922066
MESH:D051437 Renal Insufficiency Methotrexate 10.4417352296
MESH:D015427 Reperfusion Injury pirinixic acid 4.4119058328
MESH:D015427 Reperfusion Injury Superoxides 4.4118460982
MESH:D012128 Respiratory Distress Syndrome, Adult 4,4'-diphenylmethane diisocyanate 8.947973495
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 8.9411700416 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 8.9411700416
MESH:D012130 Respiratory Hypersensitivity 4,4'-diphenylmethane diisocyanate 6.1116940033
MESH:D012130 Respiratory Hypersensitivity Toluene 2,4-Diisocyanate 6.1120219652 7692837 16940033
MESH:D012135 Respiratory Sounds Chlorpyrifos 9.6517119214 16611668 11874814
MESH:D012135 Respiratory Sounds Paraquat 9.6511874814
MESH:D012135 Respiratory Sounds Pesticides 9.6517119214
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 2.6618990726
MESH:D012140 Respiratory Tract Diseases Chlorpyrifos 11.0716611668 17119214
MESH:D012140 Respiratory Tract Diseases Pesticides 11.0717119214
MESH:D012140 Respiratory Tract Diseases Toluene 2,4-Diisocyanate 11.0718447907
MESH:D012148 Restless Legs Syndrome Iron 3.5416930377
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 5.573692021
MESH:D012162 Retinal Degeneration Paraquat 5.5716458197
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 4.4216849425
MESH:D012174 Retinitis Pigmentosa Thioctic Acid 4.4216849425
MESH:D012208 Rhabdomyosarcoma Tretinoin 2.9516116481 16283617
MESH:D012220 Rhinitis Toluene 2,4-Diisocyanate 3.5219050374
MESH:D012221 Rhinitis, Allergic, Perennial Toluene 2,4-Diisocyanate 4.0512617775 15015336
MESH:D006255 Rhinitis, Allergic, Seasonal Toluene 2,4-Diisocyanate 4.2819075512
MESH:D012509 Sarcoma Doxorubicin 6.3816767912 15675481 15625365 18313854 17203757 17710206
MESH:D012509 Sarcoma Vinyl Chloride 6.3812828392
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 15.1616646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 15.1614601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 15.1614601052 16326096
MESH:D012512 Sarcoma, Ewing's Etoposide 15.1614601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 3.5817846226
MESH:D012559 Schizophrenia Clozapine 2.9918806925 11763009 11151749 20521326 19369910 20107430 17123785 20580759 17667964 17726453 20168265 18855531 16141801 20452607 20521320
MESH:D012559 Schizophrenia Haloperidol 2.991830565 19369910 20107430 18513383
MESH:D012595 Scleroderma, Systemic Vinyl Chloride 4.6614979077
MESH:D012640 Seizures 2,4-dinitrotoluene 13.9818551238
MESH:D012640 Seizures 2,6-dinitrotoluene 13.9818551238
MESH:D012640 Seizures Carbamazepine 13.989844417 15946322 16876388 19414003 9046859 16938433 16180713
MESH:D012640 Seizures Ethanol 13.989754883
MESH:D012640 Seizures Phenobarbital 13.983137016 16876388 11442880 4039156
MESH:D012640 Seizures Toluene 13.986431079 9294310
MESH:D012640 Seizures Trinitrotoluene 13.9818551238
MESH:D003294 Seizures, Febrile Phenobarbital 3.606407741
MESH:D012729 Sex Chromosome Aberrations Chlorpyrifos 4.856418539
MESH:D012871 Skin Diseases marker/mechanism 16353154
MESH:D012871 Skin Diseases Arsenic 6.9015952646 19834688 17050553 17453740 16353154 17548696 17938729 16759981 16702368 6392382 18709164
MESH:D012871 Skin Diseases Ascorbic Acid 6.9018709164
MESH:D012871 Skin Diseases monomethylarsonic acid 6.9021378128
MESH:D012871 Skin Diseases Mustard Gas 6.9012880345 15451306 16961503
MESH:D012878 Skin Neoplasms Arsenic 21.7117050553 17976673 16251483 17029826 15504454 19538983
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 21.7119755658 10029692
MESH:D012878 Skin Neoplasms cumene hydroperoxide 21.7117234724 8532709 12065085
MESH:D012878 Skin Neoplasms Doxorubicin 21.7115692506
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 21.7112065085
MESH:D012878 Skin Neoplasms Iron 21.7112065085
MESH:D012878 Skin Neoplasms Plant Extracts 21.7116517061 15173996
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 21.7116192470
MESH:D012878 Skin Neoplasms Tretinoin 21.7116467112
MESH:D012893 Sleep Disorders Carbamazepine 7.4019414003
MESH:D012893 Sleep Disorders Melatonin 7.4018182647 16919138 16897403
MESH:D020178 Sleep Disorders, Circadian Rhythm Melatonin 5.3918078449 19452292
MESH:D007319 Sleep Initiation and Maintenance Disorders Melatonin 4.0518078449
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.1115464296
MESH:D012912 Sneezing Toluene 2,4-Diisocyanate 4.2819075512 19050374
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.3817203757 16767912 15625365
MESH:D013088 Spermatocele Ethinyl Estradiol 2.7116709447
MESH:D013163 Splenomegaly Trinitrotoluene 4.0015817613
MESH:D013262 Stevens-Johnson Syndrome Carbamazepine 4.0219694795 16415921 19915237 20485159 15057820 18855540 16538176
MESH:D013272 Stomach Diseases Dexamethasone 6.3815472012
MESH:D013272 Stomach Diseases Indomethacin 6.3818545984 10486359 16184426 17207306 16113693 15472012 10192188 17160473 17638125 15038085 18209964 10215738 16280098
MESH:D013274 Stomach Neoplasms 1,3-butadiene 18.5911397402 2208121
MESH:D013274 Stomach Neoplasms arsenic trioxide 18.5917007042
MESH:D013274 Stomach Neoplasms Benzene 18.5912562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 18.592093021 20155912
MESH:D013274 Stomach Neoplasms Butylated Hydroxyanisole 18.593581430 1399818
MESH:D013274 Stomach Neoplasms Cisplatin 18.5918396642 15958060 17522103
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 18.5918456281
MESH:D013274 Stomach Neoplasms Ethanol 18.5918456281
MESH:D013274 Stomach Neoplasms Indomethacin 18.5915609394
MESH:D013274 Stomach Neoplasms Paclitaxel 18.5918506536 18396642
MESH:D013274 Stomach Neoplasms styrene oxide 18.5912562636
MESH:D013274 Stomach Neoplasms Tretinoin 18.5917261132
MESH:D013274 Stomach Neoplasms troglitazone 18.5915930296
MESH:D013274 Stomach Neoplasms Vinyl Chloride 18.5912562636
MESH:D013276 Stomach Ulcer Ascorbic Acid 20.6718726076
MESH:D013276 Stomach Ulcer Dexamethasone 20.6715138204
MESH:D013276 Stomach Ulcer Ethanol 20.6717189318 17918041 9562338 16755016 9211565 11906479
MESH:D013276 Stomach Ulcer Eugenol 20.6718543354
MESH:D013276 Stomach Ulcer Indomethacin 20.6716934674 15104355 11595415 15138204 11729361 16150113 14567935 12077510 12498302 16397915 16169175 17918041 18237397 1323529 12500499 17135157 18726076 10750652 11523592 17895592 12787963 16755016 18087811 18543354 17657623 11906479 16252198 17627676 18181030 18431645 11145282 10423059 18193104 17977527 12467913 18209962 18299717 10878458 17654042 16631530 11595431 15255614
MESH:D013276 Stomach Ulcer Melatonin 20.6711523592 16150113 12500499
MESH:D013276 Stomach Ulcer pimagedine 20.6718209962
MESH:D013276 Stomach Ulcer Plant Extracts 20.6715255614 12787963 18237397 17135157 18193104
MESH:D020521 Stroke Ascorbic Acid 3.2716403987 16517955
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.169754883
MESH:D013398 Sudden Infant Death Iron 4.2316640825
MESH:D015173 Supratentorial Neoplasms Vincristine 4.6612837982
MESH:D013576 Syndactyly Methotrexate 3.869562676
MESH:D017180 Tachycardia, Ventricular Haloperidol 3.5520210726
MESH:D024801 Tauopathies Daunorubicin 7.9116930453
MESH:D024801 Tauopathies Paclitaxel 7.9116930453
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 4.2417997062
MESH:D013733 Testicular Diseases phenethyl isothiocyanate 10.6315864552
MESH:D013733 Testicular Diseases pyrazole 10.636499806
MESH:D013733 Testicular Diseases Toluene 10.6310048760 10514026
MESH:D013736 Testicular Neoplasms Cisplatin 3.4815464296 17225452
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.4711994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.0915669648
MESH:D013953 Thymus Neoplasms Benzene 3.7410850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 2.6712697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 22.191399818 6582329 7505956 6587162 3712494
MESH:D013964 Thyroid Neoplasms arsenic trioxide 22.1919014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 22.197505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 22.1916010429 17909728
MESH:D013964 Thyroid Neoplasms Indomethacin 22.1911352223 14736730 18791128
MESH:D013964 Thyroid Neoplasms Phenobarbital 22.191399818
MESH:D013964 Thyroid Neoplasms Tretinoin 22.1916026305 17045167
MESH:D013964 Thyroid Neoplasms triadimefon 22.1917178689
MESH:D014062 Tongue Neoplasms Tretinoin 2.6916051514
MESH:D016171 Torsades de Pointes arsenic trioxide 2.7615213294
MESH:D014376 Tuberculosis Iron 5.1616597321
MESH:D014376 Tuberculosis Tretinoin 5.1616040207
MESH:D014456 Ulcer Indomethacin 3.6817380554 10574470
MESH:D001749 Urinary Bladder Neoplasms marker/mechanism 20972438 18505952
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 25.3116049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 25.3116049721
MESH:D001749 Urinary Bladder Neoplasms 2-Acetylaminofluorene 25.311399818 15289314 15867355
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 25.318074119
MESH:D001749 Urinary Bladder Neoplasms Arsenic 25.3111144890 18640142 17976673 15987713 19322015 19429237 17306315
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 25.3111780464 20435036 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 25.3117053015
MESH:D001749 Urinary Bladder Neoplasms Butylated Hydroxyanisole 25.311399818
MESH:D001749 Urinary Bladder Neoplasms Cacodylic Acid 25.3115537745
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 25.3112973940 17225452 15464296
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 25.3117653716
MESH:D014570 Urologic Diseases Diazinon 4.0516487989
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 7.9610091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 7.9610091137
MESH:D014581 Urticaria Acetaminophen 1.8710982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 9.7416803524
MESH:D002583 Uterine Cervical Neoplasms indole-3-carbinol 9.7416082211
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 9.7416129372
MESH:D014594 Uterine Neoplasms Benzene 5.7312562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 5.7314692618
MESH:D014604 Uveal Neoplasms Tretinoin 3.3716752155
MESH:D014605 Uveitis Dexamethasone 3.591336536
MESH:D014625 Vaginal Neoplasms Cisplatin 3.4215577323
MESH:D014652 Vascular Diseases Arsenic 3.5217056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.3512125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.4214671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 6.5817678736 16364871 17334414 17638931
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 6.5818097624
MESH:D020257 Ventricular Remodeling Plant Extracts 4.1018097624
MESH:D014820 Vitiligo Tretinoin 2.8916761959
MESH:D014839 Vomiting Cisplatin 7.4611897121
MESH:D014839 Vomiting Indomethacin 7.4611897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.0115886252
MESH:D015430 Weight Gain Clozapine 6.2416402076 17502770 20564506 20107430 20521320 16141801
MESH:D015430 Weight Gain Dietary Fats 6.2416723640
MESH:D015431 Weight Loss Clozapine 3.8617933447
MESH:D009396 Wilms Tumor Tretinoin 2.8816287080
MESH:D014947 Wounds and Injuries Plant Extracts 3.2220213670 19894650
Pathway ID Pathway Name
REACT:13433 Biological oxidations
KEGG:00982 Drug metabolism - cytochrome P450
KEGG:00480 Glutathione metabolism
KEGG:00980 Metabolism of xenobiotics by cytochrome P450
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA182
    • Releated gene ID Related gene Name
    PA27092CYP1A1
    PA29028GSTP1
    PA18NAT2
    PA182GSTM1
    Releated disease ID Related disease Name
    PA444320Graft vs Host Disease
    PA134850491Transplantation
    PA162263534Ototoxicity
    PA446975Neurotoxicity Syndromes
    PA443512Urinary Bladder Neoplasms
    PA445018Cardiomyopathies
    PA445425Prostatic Neoplasms
    PA443797Coronary Disease
    PA445062Neoplasms
    PA445742Stomach Neoplasms
    PA443622Carcinoma, Non-Small-Cell Lung
    PA443340Anemia
    PA445301Peripheral Nervous System Diseases
    PA445846Thrombocytopenia
    PA443560Breast Neoplasms
    PA444552Hypertension
    PA446108Colorectal Neoplasms
    PA444434Hepatic Veno-Occlusive Disease
    PA444760Leukemia, Myeloid, Acute
    PA446357Neoplasms, Second Primary
    PA444065Epilepsy
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    PA444818Lung Neoplasms
    PA443485Basal Cell Nevus Syndrome
    PA444355Hearing Disorders
    PA446171Leukemia, Myelogenous, Chronic, BCR-ABL Positive
    PA444101Esophageal Neoplasms
    PA443890Diabetes Mellitus, Type 2
    PA443899Diarrhea
    PA445113Neutropenia
    PA444257Gastrointestinal Neoplasms
    PA443937Drug Toxicity
    PA444801Liver Diseases
    PA446411Endometrial Neoplasms
    PA443319Alzheimer Disease
    PA443224Abnormalities, Drug-Induced
    PA164925725Toxic liver disease
    Releated drug ID Related drug Name
    PA449167cyclosporine
    PA449247dexamethasone
    PA164713176Platinum compounds
    PA451668thiotepa
    PA130232992bevacizumab
    PA130620651anthracyclines and related substances
    PA449383docetaxel
    PA451283rosiglitazone
    PA448515azathioprine
    PA131285527oxaliplatin
    PA450112isoniazid
    PA449014cisplatin
    PA449165cyclophosphamide
    PA128406956fluorouracil
    PA452604xenobiotics
    PA448926chlorambucil
    PA449412doxorubicin
    PA450526mitoxantrone
    PA451611teniposide
    PA448691busulfan
    PA450354melphalan
    PA448785carbamazepine
    PA448492asparaginase
    PA449177cytarabine
    PA449212daunorubicin
    PA449552etoposide
    PA450198leucovorin
    PA450379mercaptopurine
    PA450428methotrexate
    PA451100prednisone
    PA451879vincristine
    PA452621antineoplastic agents
    PA448365amifostine
    PA448803carboplatin
    PA450761paclitaxel
    PA448771capecitabine
    PA450085irinotecan
    PA451576tacrine
    PA448406amoxicillin
    PA164712405Antibacterials For Systemic Use
    PA164712462Antiinflammatory agents, non-steroids
    PA164742987clavulanate
    PA164712471Antimycobacterials
    PA164712708Drugs For Treatment Of Tuberculosis
    PA451799troglitazone
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00143 - BSS Plus Dietary supplement;Micronutrient
    DB01834 - (9r,10r)-9-(S-Glutathionyl)-10-Hydroxy-9,10-Dihydrophenanthrene
    DB02165 - Zinc Trihydroxide
    DB02458 - Glutathione S-(2,4 Dinitrobenzene)
    DB03314 - Fluorotryptophane
    DB04187 - (9s,10s)-9-(S-Glutathionyl)-10-Hydroxy-9,10-Dihydrophenanthrene
    DB04412 - 1-(S-Glutathionyl)-2,4-Dinitrobenzene
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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