AutismKB 2.0

Annotation Detail for GSTM2


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Basic Information Top
Gene Symbol:GSTM2 ( GST4,GSTM,GSTM2-2,GTHMUS,MGC117303 )
Gene Full Name: glutathione S-transferase mu 2 (muscle)
Band: 1p13.3
Quick LinksEntrez ID:2946; OMIM: 138380; Uniprot ID:GSTM2_HUMAN; ENSEMBL ID: ENSG00000213366; HGNC ID: 4634
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-4061glutathione-mediated detoxification
Pathway IDPathway Name
hsa00480Glutathione metabolism
hsa00980Metabolism of xenobiotics by cytochrome P450
hsa00982Drug metabolism - cytochrome P450
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2236Cardiovascular disease
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C042630 1-chloro-2,4-dinitrobenzene-glutathione conjugate GSTM2 protein affects the metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugateaffects metabolic processing 11684093
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of GSTM2 mRNAaffects expression 21346803
C099328 2-allylphenol 2-allylphenol results in decreased activity of GSTM2 proteindecreases activity 8620581
C082398 2-S-glutathionylcaffeic acid 2-S-glutathionylcaffeic acid results in decreased activity of GSTM2 proteindecreases activity 8340025
C023035 3,4,5,3',4'-pentachlorobiphenyl 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM2 mRNAincreases expression 18042819
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of GSTM2 mRNAdecreases expression 18648102
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of GSTM2 mRNAdecreases expression 18289764
C010407 4-chloronitrobenzene GSTM2 protein affects the metabolism of [4-chloronitrobenzene analog co-treated with Glutathione]affects cotreatment|affects metabolic processing 8973562
C027576 4-hydroxy-2-nonenal [GSTM1 protein binds to GSTM2 protein] which affects the metabolism of 4-hydroxy-2-nonenal analogaffects binding|affects metabolic processing 11256969
C027576 4-hydroxy-2-nonenal GSTM2 protein results in decreased susceptibility to 4-hydroxy-2-nonenaldecreases response to substance 15829614
C027576 4-hydroxy-2-nonenal [GSTM1 protein binds to GSTM2 protein] which affects the metabolism of 4-hydroxy-2-nonenal analogaffects binding|affects metabolic processing 11256969
C027576 4-hydroxy-2-nonenal GSTM2 protein affects the metabolism of 4-hydroxy-2-nonenal analogaffects metabolic processing 11256969
C065250 4-hydroxy-equilenin 4-hydroxy-equilenin results in decreased expression of GSTM2 mRNAdecreases expression 15135645
C099327 4-propylphenol 4-propylphenol results in decreased activity of GSTM2 proteindecreases activity 8620581
D000082 Acetaminophen Acetaminophen affects the expression of GSTM2 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in decreased expression of GSTM2 mRNAdecreases expression 16611625
D000082 Acetaminophen Acetaminophen results in decreased expression of GSTM2 mRNAdecreases expression 18346771
D012436 S-Adenosylmethionine S-Adenosylmethionine inhibits the reaction [Dicarbethoxydihydrocollidine results in increased expression of GSTM2 mRNA]decreases reaction|increases expression 18098314
C006426 aflatoxin B1-2,3-oxide GSTM2 protein affects the metabolism of [aflatoxin B1-2,3-oxide co-treated with Glutathione]affects cotreatment|affects metabolic processing 10869451
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GSTM2 mRNAaffects expression 16483693
C004984 apocarotenal apocarotenal results in decreased expression of GSTM2 mRNAdecreases expression 17034753
D001414 Bacitracin Bacitracin results in increased expression of GSTM2 mRNAincreases expression 18289764
D001564 Benzo(a)pyrene GSTM2 protein results in decreased susceptibility to Benzo(a)pyrenedecreases response to substance 19900515
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of GSTM2 mRNAdecreases expression 20127859
C005465 benzothiazole benzothiazole results in increased expression of GSTM2 mRNAincreases expression 8951341
C025383 benzylideneacetone GSTM2 protein affects the metabolism of benzylideneacetoneaffects metabolic processing 1859377
D019207 beta Carotene beta Carotene results in increased expression of GSTM2 mRNAincreases expression 17034753
C006780 bisphenol A bisphenol A results in decreased expression of GSTM2 mRNAdecreases expression 15901920
C032036 bromobenzene bromobenzene metabolite binds to GSTM2 proteinaffects binding 17305373
D002083 Butylated Hydroxyanisole Butylated Hydroxyanisole results in increased expression of GSTM2 proteinincreases expression 11991805
1859377
D002084 Butylated Hydroxytoluene Butylated Hydroxytoluene results in increased expression of GSTM2 mRNAincreases expression 18539377
12082028
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of GSTM2 mRNAdecreases expression 15336504
D020122 tert-Butylhydroperoxide GSTM2 protein results in decreased susceptibility to tert-Butylhydroperoxidedecreases response to substance 15003993
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of GSTM2 mRNAincreases expression 15336504
15003993
D002087 Butyrates Butyrates results in increased expression of and results in increased activity of GSTM2 proteinincreases activity|increases expression 12896903
D002087 Butyrates Butyrates results in increased expression of GSTM2 mRNAincreases expression 12896903
15746163
C040048 caffeic acid caffeic acid results in decreased activity of GSTM2 proteindecreases activity 8340025
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of GSTM2 mRNAdecreases expression 16239168
18346771
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of GSTM2 mRNAincreases expression 17805973
D002713 Chlorine Chlorine results in decreased expression of GSTM2 mRNAdecreases expression 18636392
D002713 Chlorine [Ozone co-treated with Chlorine] affects the expression of GSTM2 mRNAaffects cotreatment|affects expression 18636392
D004390 Chlorpyrifos Chlorpyrifos affects the expression of GSTM2 mRNAaffects expression 19440498
D019826 Cholic Acid Cholic Acid results in increased expression of GSTM2 mRNAincreases expression 17521389
C012842 Cibacron Blue F 3GA Cibacron Blue F 3GA results in decreased activity of GSTM2 proteindecreases activity 8968379
D002995 Clofibric Acid Clofibric Acid affects the expression of GSTM2 mRNAaffects expression 17602206
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of GSTM2 mRNAaffects cotreatment|affects expression 17602206
D003024 Clozapine Clozapine results in decreased expression of GSTM2 mRNAdecreases expression 15860345
D003345 Corticosterone Corticosterone results in increased expression of GSTM2 mRNAincreases expression 15755911
D003345 Corticosterone Corticosterone results in increased expression of GSTM2 proteinincreases expression 15755911
C007164 cumene hydroperoxide GSTM2 protein affects the metabolism of cumene hydroperoxideaffects metabolic processing 11684093
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of GSTM2 mRNAincreases expression 17654400
D003520 Cyclophosphamide Cyclophosphamide results in decreased expression of GSTM2 mRNAdecreases expression 11906922
C014347 decitabine [decitabine affects the methylation of GSTM2 promoter] which affects the expression of GSTM2 mRNAaffects expression|affects methylation 18664505
C014347 decitabine [decitabine affects the methylation of GSTM2 promoter] which affects the expression of GSTM2 proteinaffects expression|affects methylation 18664505
C014347 decitabine decitabine results in increased expression of GSTM2 mRNAincreases expression 19900515
C014347 decitabine trichostatin A promotes the reaction [[decitabine affects the methylation of GSTM2 promoter] which affects the expression of GSTM2 protein]affects expression|affects methylation|increases reaction 18664505
D003907 Dexamethasone Dexamethasone affects the expression of GSTM2 mRNAaffects expression 15102944
D003907 Dexamethasone Dexamethasone results in increased expression of GSTM2 mRNAincreases expression 1394205
D003976 Diazinon Diazinon results in increased expression of GSTM2 mRNAincreases expression 19440498
D003997 Dicarbethoxydihydrocollidine Dicarbethoxydihydrocollidine results in increased expression of GSTM2 mRNAincreases expression 18098314
D003997 Dicarbethoxydihydrocollidine S-Adenosylmethionine inhibits the reaction [Dicarbethoxydihydrocollidine results in increased expression of GSTM2 mRNA]decreases reaction|increases expression 18098314
D002945 Cisplatin GSTM2 protein affects the susceptibility to Cisplatinaffects response to substance 16217747
C121718 dicyclanil [dicyclanil co-treated with Diethylnitrosamine] results in increased expression of GSTM2 mRNAaffects cotreatment|increases expression 19182440
C121718 dicyclanil dicyclanil results in increased expression of GSTM2 mRNAincreases expression 15664270
C121718 dicyclanil Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with dicyclanil] results in increased expression of GSTM2 mRNA]affects cotreatment|decreases reaction|increases expression 19182440
D004051 Diethylhexyl Phthalate Diethylhexyl Phthalate results in decreased expression of GSTM2 proteindecreases expression 8914623
D004052 Diethylnitrosamine [dicyclanil co-treated with Diethylnitrosamine] results in increased expression of GSTM2 mRNAaffects cotreatment|increases expression 19182440
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of GSTM2 mRNAincreases expression 17942915
D004052 Diethylnitrosamine MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of GSTM2 mRNA]decreases reaction|increases expression 17942915
D004052 Diethylnitrosamine Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with dicyclanil] results in increased expression of GSTM2 mRNA]affects cotreatment|decreases reaction|increases expression 19182440
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of GSTM2 mRNAaffects cotreatment|affects expression 17602206
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM2 mRNAaffects cotreatment|decreases expression 18544905
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM2 mRNAaffects cotreatment|increases expression 18544905
D004052 Diethylnitrosamine [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM2 mRNAaffects cotreatment|decreases expression 18253720
18775883
D004137 Dinitrochlorobenzene GSTM2 protein affects the metabolism of Dinitrochlorobenzeneaffects metabolic processing 3570286
D004137 Dinitrochlorobenzene GSTM2 protein affects the metabolism of Dinitrochlorobenzeneaffects metabolic processing 10869451
D004137 Dinitrochlorobenzene GSTM2 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione]affects cotreatment|affects metabolic processing 2375757
D004137 Dinitrochlorobenzene GSTM2 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog]affects cotreatment|affects metabolic processing 2375757
D004137 Dinitrochlorobenzene Dinitrochlorobenzene affects the activity of GSTM2 proteinaffects activity 9794801
D004137 Dinitrochlorobenzene Dinitrochlorobenzene promotes the reaction [GSTM2 protein affects the metabolism of Glutathione]affects metabolic processing|increases reaction 9794801
D004137 Dinitrochlorobenzene Dinitrochlorobenzene results in increased expression of GSTM2 proteinincreases expression 9794801
D004178 Diquat Diquat results in decreased expression of GSTM2 mRNAdecreases expression 7676460
C042986 ebselen ebselen binds to and results in decreased activity of [GSTM1 protein binds to GSTM2 protein]affects binding|decreases activity 8147899
C045651 epigallocatechin gallate epigallocatechin gallate results in increased expression of GSTM2 mRNAincreases expression 10927022
C045651 epigallocatechin gallate epigallocatechin gallate results in increased expression of GSTM2 proteinincreases expression 10927022
D004852 Epoxy Compounds GSTM2 protein affects the metabolism of Epoxy Compoundsaffects metabolic processing 8924604
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of GSTM2 mRNAdecreases expression 15576828
12655037
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of GSTM2 mRNAincreases expression 12082028
D005031 Ethylenethiourea Ethylenethiourea results in increased expression of GSTM2 mRNAincreases expression 18801409
D005054 Eugenol Eugenol analog results in decreased activity of GSTM2 proteindecreases activity 8620581
D011345 Fenofibrate [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM2 mRNAaffects cotreatment|decreases expression 18775883
18253720
D011345 Fenofibrate Fenofibrate results in decreased expression of GSTM2 mRNAdecreases expression 18775883
C009264 fenoprop fenoprop results in decreased expression of GSTM2 proteindecreases expression 8914623
D005419 Flavonoids Flavonoids results in decreased expression of GSTM2 mRNAdecreases expression 18035473
C056933 fumonisin B1 fumonisin B1 results in increased expression of GSTM2 mRNAincreases expression 16221962
C007835 geniposide geniposide results in increased expression of GSTM2 mRNAincreases expression 14646352
C007835 geniposide geniposide results in increased expression of GSTM2 proteinincreases expression 14646352
D005912 Gliotoxin Gliotoxin results in decreased expression of GSTM2 mRNAdecreases expression 18346771
D005938 Glucocorticoids Glucocorticoids results in increased expression of GSTM2 mRNAincreases expression 1944302
D005961 Glucosinolates Glucosinolates results in increased expression of GSTM2 proteinincreases expression 15570060
D005978 Glutathione Glutathione binds to GSTM2 proteinaffects binding 2337594
D005978 Glutathione GSTM2 protein affects the metabolism of Glutathioneaffects metabolic processing 10858281
D005978 Glutathione GSTM2 protein affects the metabolism of [aflatoxin B1-2,3-oxide co-treated with Glutathione]affects cotreatment|affects metabolic processing 10869451
D005978 Glutathione GSTM2 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione]affects cotreatment|affects metabolic processing 2375757
D005978 Glutathione GSTM2 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog]affects cotreatment|affects metabolic processing 2375757
D005978 Glutathione Dinitrochlorobenzene promotes the reaction [GSTM2 protein affects the metabolism of Glutathione]affects metabolic processing|increases reaction 9794801
D005978 Glutathione GSTM2 protein affects the metabolism of [4-chloronitrobenzene analog co-treated with Glutathione]affects cotreatment|affects metabolic processing 8973562
D005978 Glutathione GSTM2 protein affects the metabolism of Glutathioneaffects metabolic processing 8924604
D005978 Glutathione GSTM2 protein affects the metabolism of [styrene oxide co-treated with Glutathione]affects cotreatment|affects metabolic processing 2604743
D006220 Haloperidol Haloperidol results in decreased expression of GSTM2 mRNAdecreases expression 15860345
D006581 Hexachlorobenzene Hexachlorobenzene results in increased expression of GSTM2 mRNAincreases expression 15159207
C033550 hexylglutathione hexylglutathione results in decreased activity of GSTM2 proteindecreases activity 10858281
C029424 hydrazine hydrazine results in decreased expression of GSTM2 mRNAdecreases expression 15370871
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of GSTM2 mRNAincreases expression 15003993
D007213 Indomethacin Indomethacin results in increased expression of GSTM2 mRNAincreases expression 18299717
C031050 isomethyleugenol isomethyleugenol results in decreased activity of GSTM2 proteindecreases activity 8620581
C098607 JP8 aviation fuel JP8 aviation fuel affects the expression of GSTM2 mRNAaffects expression 12539871
D007654 Ketoconazole Ketoconazole affects the expression of GSTM2 mRNAaffects expression 18289764
D007659 Ketones GSTM2 protein affects the metabolism of Ketonesaffects metabolic processing 8924604
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM2 mRNAaffects cotreatment|decreases expression 18544905
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM2 mRNAaffects cotreatment|increases expression 18544905
C099406 L 742694 L 742694 affects the expression of GSTM2 mRNAaffects expression 15102944
C008261 lead acetate lead acetate results in decreased expression of GSTM2 proteindecreases expression 9750042
C008261 lead acetate lead acetate results in increased expression of GSTM2 proteinincreases expression 9750042
C482199 lipopolysaccharide, E coli O55-B5 lipopolysaccharide, E coli O55-B5 results in decreased expression of GSTM2 mRNAdecreases expression 18346771
D008701 Methapyrilene Methapyrilene results in decreased expression of GSTM2 mRNAdecreases expression 16393664
C005223 methyleugenol methyleugenol results in decreased activity of GSTM2 proteindecreases activity 8620581
D009151 Mustard Gas Mustard Gas results in decreased expression of GSTM2 mRNAdecreases expression 18955075
D009255 Nafenopin Nafenopin results in decreased expression of GSTM2 proteindecreases expression 8914623
C031721 naphthalene naphthalene affects the expression of GSTM2 proteinaffects expression 10959795
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in increased expression of GSTM2 mRNAincreases expression 18289764
D009532 Nickel Nickel results in decreased expression of GSTM2 mRNAdecreases expression 19440498
D005996 Nitroglycerin GSTM2 protein affects the metabolism of Nitroglycerinaffects metabolic processing 8968379
D010126 Ozone [Ozone co-treated with Chlorine] affects the expression of GSTM2 mRNAaffects cotreatment|affects expression 18636392
D010126 Ozone Ozone results in decreased expression of GSTM2 mRNAdecreases expression 16716893
D010269 Paraquat Paraquat results in increased expression of GSTM2 mRNAincreases expression 16128001
D010269 Paraquat Paraquat results in decreased expression of GSTM2 mRNAdecreases expression 17935786
D010269 Paraquat Paraquat results in increased expression of GSTM2 mRNAincreases expression 16555045
C494474 perchlorate perchlorate results in increased expression of GSTM2 mRNAincreases expression 18801409
C023036 perfluorooctanoic acid perfluorooctanoic acid affects the expression of GSTM2 mRNAaffects expression 18281256
D044262 Prostaglandin H2 GSTM2 protein affects the metabolism of Prostaglandin H2affects metabolic processing 10905636
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of GSTM2 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of GSTM2 mRNAincreases expression 19482888
19270015
D010634 Phenobarbital Phenobarbital results in increased expression of GSTM2 mRNAincreases expression 12832660
12082028
D010795 Phthalic Acids Phthalic Acids results in decreased expression of GSTM2 mRNAdecreases expression 15728792
C006253 pirinixic acid pirinixic acid results in decreased expression of GSTM2 mRNAdecreases expression 17426115
20059764
16221962
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in decreased expression of GSTM2 mRNA]decreases expression|increases reaction 20059764
D010936 Plant Extracts Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with dicyclanil] results in increased expression of GSTM2 mRNA]affects cotreatment|decreases reaction|increases expression 19182440
D010936 Plant Extracts Plant Extracts results in increased expression of GSTM2 proteinincreases expression 15570060
D011374 Progesterone Progesterone affects the expression of GSTM2 mRNAaffects expression 17251523
C045950 propiconazole propiconazole results in increased expression of GSTM2 mRNAincreases expression 16730040
D015232 Dinoprostone GSTM2 protein affects the chemical synthesis of Dinoprostoneaffects chemical synthesis 10905636
D011458 Prostaglandins E GSTM2 protein affects the chemical synthesis of Prostaglandins Eaffects chemical synthesis 10905636
C052785 rebamipide rebamipide results in increased expression of GSTM2 mRNAincreases expression 18299717
C058186 S-hexylglutathione-sepharose S-hexylglutathione-sepharose binds to GSTM2 proteinaffects binding 2337594
C017947 sodium arsenite sodium arsenite results in increased expression of GSTM2 mRNAincreases expression 14691202
D013311 Streptozocin Streptozocin results in increased expression of GSTM2 mRNAincreases expression 16684804
D013311 Streptozocin vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTM2 mRNA]decreases reaction|increases expression 16684804
C013690 styrene oxide GSTM2 protein affects the metabolism of styrene oxideaffects metabolic processing 1638515
C013690 styrene oxide GSTM2 protein affects the metabolism of [styrene oxide co-treated with Glutathione]affects cotreatment|affects metabolic processing 2604743
D013448 Sulfobromophthalein Sulfobromophthalein results in decreased activity of GSTM2 proteindecreases activity 8968379
D013619 Tacrine Tacrine results in increased expression of GSTM2 mRNAincreases expression 12832660
C517826 tetrabrominated diphenyl ether 47 tetrabrominated diphenyl ether 47 results in increased expression of GSTM2 mRNAincreases expression 20056577
D013749 Tetrachlorodibenzodioxin NFE2L2 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTM2 mRNA]affects reaction|increases expression 19474220
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of GSTM2 mRNAaffects binding|increases expression 16214954
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of GSTM2 mRNAincreases expression 19474220
18796159
18172886
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of GSTM2 proteinincreases expression 12361703
D013844 Thiazoles Thiazoles results in increased expression of GSTM2 mRNAincreases expression 8951341
D013844 Thiazoles Thiazoles results in increased expression of GSTM2 proteinincreases expression 8951341
D013853 Thioacetamide Thioacetamide results in increased expression of GSTM2 mRNAincreases expression 15497818
D014050 Toluene Toluene affects the expression of GSTM2 mRNAaffects expression 18653662
D014212 Tretinoin Tretinoin results in decreased expression of GSTM2 mRNAdecreases expression 16604517
C012589 trichostatin A trichostatin A affects the expression of GSTM2 mRNAaffects expression 18664505
C012589 trichostatin A trichostatin A promotes the reaction [[decitabine affects the methylation of GSTM2 promoter] which affects the expression of GSTM2 protein]affects expression|affects methylation|increases reaction 18664505
C010360 triethyllead triethyllead results in decreased expression of GSTM2 mRNAdecreases expression 9020200
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in decreased expression of GSTM2 mRNAdecreases expression 17982090
D014303 Trinitrotoluene Trinitrotoluene affects the expression of GSTM2 mRNAaffects expression 21346803
C034028 vanadyl sulfate vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTM2 mRNA]decreases reaction|increases expression 16684804
C025643 vinclozolin vinclozolin affects the expression of GSTM2 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Diethylhexyl Phthalate 12.816734493
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 12.816195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 12.8115322242 11752688 14514962
MESH:D000014 Abnormalities, Drug-Induced Trinitrotoluene 12.817525203
MESH:D000138 Acidosis Ammonium Chloride 2.6218287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 2.9817505938
MESH:D058186 Acute Kidney Injury Cisplatin 3.1112690470 15814532 17670903
MESH:D055371 Acute Lung Injury Chlorine 10.3320601635
MESH:D055371 Acute Lung Injury Nickel 10.3316166738
MESH:D055371 Acute Lung Injury pirinixic acid 10.3318653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 9.5820127859 20464547
MESH:D000230 Adenocarcinoma Cisplatin 9.5811798837 17638652
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.5814692618
MESH:D000230 Adenocarcinoma Ethylenethiourea 9.587955072
MESH:D000230 Adenocarcinoma Indomethacin 9.5816537180
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 10.693712494
MESH:D000236 Adenoma Benzo(a)pyrene 10.696695378
MESH:D000236 Adenoma Diethylnitrosamine 10.6910737359 6695378
MESH:D000236 Adenoma Indomethacin 10.6911497255
MESH:D018248 Adenoma, Liver Cell 3,4,5,3',4'-pentachlorobiphenyl 28.7116628245
MESH:D018248 Adenoma, Liver Cell dicyclanil 28.7117162532
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 28.7117620307 17162532 19061943 18056438 19052882 16434500
MESH:D018248 Adenoma, Liver Cell Phenobarbital 28.7117620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 28.7116434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 28.7116835633
MESH:D011125 Adenomatous Polyposis Coli Dinoprostone 4.1917942926
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.7415276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 3.9416712894 17306315
MESH:D000380 Agranulocytosis Clozapine 4.1314617031 12649775 16160616
MESH:D000382 Agricultural Workers' Diseases Chlorpyrifos 9.1911874814 16611668 17119214
MESH:D000382 Agricultural Workers' Diseases Diazinon 9.1916487989
MESH:D000382 Agricultural Workers' Diseases Paraquat 9.1911874814
MESH:D000505 Alopecia Tretinoin 2.8315955085
MESH:D016301 Alveolar Bone Loss Indomethacin 4.4117225004
MESH:D000544 Alzheimer Disease Indomethacin 6.6917627676 15579461
MESH:D000544 Alzheimer Disease Ozone 6.6915513908
MESH:D000544 Alzheimer Disease Plant Extracts 6.6916962711
MESH:D000544 Alzheimer Disease Tacrine 6.6912725862
MESH:D000690 Amyotrophic Lateral Sclerosis 4-hydroxy-2-nonenal 3.4310965797
MESH:D000740 Anemia 4-chloronitrobenzene 6.733710033
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.7311748828
MESH:D000799 Angioedema Acetaminophen 2.8810982225
MESH:D001008 Anxiety Disorders vinclozolin 2.8619015723
MESH:D001014 Aortic Aneurysm Dinoprostone 9.2010231640
MESH:D001014 Aortic Aneurysm Indomethacin 9.2010231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 14.8019183758
MESH:D017544 Aortic Aneurysm, Abdominal Dinoprostone 14.8010388637
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 14.8010388637
MESH:D001161 Arteriosclerosis Cyclophosphamide 7.1115014928
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 7.1111256880
MESH:D018771 Arthralgia Indomethacin 4.212160914
MESH:D001169 Arthritis, Experimental Dexamethasone 12.0617659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 12.0615885639
MESH:D001169 Arthritis, Experimental Plant Extracts 12.0614686799
MESH:D001169 Arthritis, Experimental Tretinoin 12.0616412693
MESH:D001172 Arthritis, Rheumatoid Indomethacin 5.3911248219
MESH:D001172 Arthritis, Rheumatoid Ozone 5.3915570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 5.3916292516
MESH:D001249 Asthma epigallocatechin gallate 7.8216516891
MESH:D001249 Asthma Mustard Gas 7.8210378619
MESH:D001249 Asthma Ozone 7.8217854713 16373670
MESH:D001249 Asthma Tretinoin 7.8216456186
MESH:D001289 Attention Deficit Disorder with Hyperactivity Phthalic Acids 3.6620106747
MESH:D001321 Autistic Disorder Acetaminophen 2.6918445737
MESH:D001321 Autistic Disorder Glutathione 2.6918929414 19056591 19267885 16917939
MESH:D001321 Autistic Disorder Haloperidol 2.6918080171 19368416
MESH:D001321 Autistic Disorder S-Adenosylmethionine 2.6916917939 19056591
MESH:D001321 Autistic Disorder tetrabrominated diphenyl ether 47 2.6919211157
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 4.1419761891
MESH:D001471 Barrett Esophagus Tretinoin 3.4916935849
MESH:D001477 Bartter Syndrome Dinoprostone 9.6315976003
MESH:D001477 Bartter Syndrome Indomethacin 9.6310684365
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.0511289319 1440618
MESH:D001768 Blister Mustard Gas 4.2119167455
MESH:D001778 Blood Coagulation Disorders pirinixic acid 14.9519483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 14.9512125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 14.9519483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 14.9516206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.8315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.0815746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 3.9314601052
MESH:D001862 Bone Resorption bisphenol A 3.0111985600
MESH:D001929 Brain Edema Indomethacin 4.0611481608
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.3717868700
MESH:D001930 Brain Injuries Progesterone 3.3415845082 15665606 15380490
MESH:D002545 Brain Ischemia beta Carotene 11.8616157235
MESH:D002545 Brain Ischemia Indomethacin 11.8612524144
MESH:D002545 Brain Ischemia Plant Extracts 11.8616041641
MESH:D001932 Brain Neoplasms Epoxy Compounds 4.9512562636
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 9.4420146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 9.4417123778
MESH:D001943 Breast Neoplasms Cisplatin 9.4418382427 19526202
MESH:D001943 Breast Neoplasms Cyclophosphamide 9.4417388661 17020986 18234424 16978400 18323546 12006526 11325840 15093573 15136595
MESH:D001943 Breast Neoplasms decitabine 9.4418320071 19208741
MESH:D001943 Breast Neoplasms Diethylnitrosamine 9.4417474063
MESH:D001943 Breast Neoplasms Epoxy Compounds 9.4412562636
MESH:D001943 Breast Neoplasms Hexachlorobenzene 9.4412709520 15061365
MESH:D001943 Breast Neoplasms Indomethacin 9.4417401462
MESH:D001943 Breast Neoplasms methyleugenol 9.4411921183
MESH:D001943 Breast Neoplasms Nickel 9.4415986119
MESH:D001943 Breast Neoplasms Progesterone 9.4415562024 17614352 16175315
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 9.4420435547
MESH:D001943 Breast Neoplasms Tretinoin 9.4416873071 16443354 16166294
MESH:D016535 Bronchial Hyperreactivity Ozone 2.9019059883 18417511 14754758 18315731 17626835 15516495 16777450
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.2115286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.0117687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.6416813970
MESH:D002056 Burns Indomethacin 3.7810459503
MESH:D002057 Burns, Chemical Plant Extracts 4.379625245
MESH:D002100 Cachexia Indomethacin 9.2715141370 15625704 11239499 16537180
MESH:D002100 Cachexia Ozone 9.2716183385
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 2.8615700767 16192424 15721981 16050911 15673190 18705752 16227642 16097048 10355542 3786805 16011737 16124888
MESH:D002276 Carcinoid Tumor Streptozocin 4.6416051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.0216835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.1916168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 27.6316705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 27.637296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 27.633084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 27.6318788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 27.6317982673
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 27.6319701751
MESH:D006528 Carcinoma, Hepatocellular dicyclanil 27.6317162532
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 27.6316540662 3084413 20524982 16569478 18691550 17055752 16681979 16935385 18785209 19539802 18665156 10672840 18978308 19171122 20432363 19383236 20084675 17138121 20512989 16878318 19335982 20727157 19394651 19919837 3581430 17978847 19418558 17761372 19519916 20514400 18971187 16502159 20935162 19052882 16698587 16328049 18494052 19107877 11831363 18393292 17428255 17162532 18056438 19208518 16830150 20101231 16807293 18788625 10737359 18506893 20007298 19701751 16288022 20214788 19822196 18210153 16779866 21159647 17173139
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 27.6316391822
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 27.6320935162 17173139 6705139 20007298 1701930
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 27.6318834353
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 27.6317306315 16507464 15276417
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 27.6317997003
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 27.631917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.0417123778
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 8.4116152834
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 8.4111053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.4018791128 14736730 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung marker/mechanism 19900515
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.6216685392 12023789
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 7.617296757
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 7.6116201981
MESH:D002292 Carcinoma, Renal Cell Indomethacin 7.6117341418
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 15.6520419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 15.6517066447 18337622 6189445
MESH:D002294 Carcinoma, Squamous Cell decitabine 15.6519215824
MESH:D002294 Carcinoma, Squamous Cell Glutathione 15.6517015178
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 15.6512636206 15482327
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 15.6518572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 15.6516051514 16096774
MESH:D006332 Cardiomegaly Plant Extracts 4.9017645561
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 4.9016120746 18670907 18850075
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 2.8216936243
MESH:D002375 Catalepsy Haloperidol 3.971977408 15215559
MESH:D002386 Cataract Acetaminophen 8.6310977129
MESH:D002386 Cataract Tretinoin 8.6317460283
MESH:D002386 Cataract Trinitrotoluene 8.6315817613 14694615
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 10.247505956
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 10.2417174075 7505956 21159647 2727394
MESH:D002471 Cell Transformation, Neoplastic Dinoprostone 10.2416192471
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 10.2420056578 19524636
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.334080065
MESH:D002547 Cerebral Palsy Toluene 4.909294310
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.6416129372
MESH:D018281 Cholangiocarcinoma 3,4,5,3',4'-pentachlorobiphenyl 16.3816628245
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 16.3819052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 16.3816835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 16.3818291259
MESH:D002761 Cholangitis 1-Naphthylisothiocyanate 5.2412912871
MESH:D002764 Cholecystitis Indomethacin 4.2111181007
MESH:D002779 Cholestasis 1-Naphthylisothiocyanate 13.1112927374 15913567 15500046 16629650 18164287 18590720 19486331 7624871
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.119022650 19486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.1117333356 16919318 11677210 17681005 17110522 16105132 15861022
MESH:D002779 Cholestasis pirinixic acid 13.1119176532
MESH:D002780 Cholestasis, Intrahepatic 1-Naphthylisothiocyanate 4.8919407337 10220858
MESH:D002822 Choriocarcinoma Tretinoin 4.1916461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 4.0415668235 8697196 12621046 15340226 16354765
MESH:D002972 Cleft Palate Tretinoin 4.049407595
MESH:D003072 Cognition Disorders Clozapine 4.0417123785
MESH:D003092 Colitis Tretinoin 6.7317035595
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 6.7317991707 16474422 18023891 18200517 16867261 16782535 17936198 16804969 11698051
MESH:D003093 Colitis, Ulcerative Dinitrochlorobenzene 5.0217373747 19159591
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 5.0217276891
MESH:D003110 Colonic Neoplasms Butyrates 5.9015936596
MESH:D003110 Colonic Neoplasms decitabine 5.9017616700
MESH:D003110 Colonic Neoplasms Dexamethasone 5.9015824018
MESH:D003110 Colonic Neoplasms Indomethacin 5.9011260862 15786552 15936596 15963497 15637740 15625704
MESH:D015179 Colorectal Neoplasms Cisplatin 2.7615273666
MESH:D015179 Colorectal Neoplasms decitabine 2.7618981723
MESH:D015179 Colorectal Neoplasms Indomethacin 2.7611197048 12606626 17054584 18059344
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 6.5417141729 14669216
MESH:D000013 Congenital Abnormalities Trinitrotoluene 6.5415095906
MESH:D003328 Coronary Thrombosis methyleugenol 4.8616048847
MESH:D018352 Coronavirus Infections Indomethacin 4.7517302372
MESH:D019465 Craniofacial Abnormalities 3,4,5,3',4'-pentachlorobiphenyl 8.7217686920
MESH:D019465 Craniofacial Abnormalities Dexamethasone 8.7217728286
MESH:D019465 Craniofacial Abnormalities Glucocorticoids 8.7218281261
MESH:D019465 Craniofacial Abnormalities lead acetate 8.7219769572
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 8.7210048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Toluene 8.729294310
MESH:D019465 Craniofacial Abnormalities Tretinoin 8.729142499 10589399 16925845 17551590 9664655 14991402 8800419 9224671 9211117 9125849
MESH:D003456 Cryptorchidism vinclozolin 3.4414966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 8.1618551238
MESH:D003490 Cyanosis Trinitrotoluene 8.1618551238
MESH:D003550 Cystic Fibrosis Glutathione 3.6619747007
MESH:D003556 Cystitis Cyclophosphamide 4.0311948286 17010015 18372110 16651033 10700343 18710439 18295254 16413132 12161096 15276878 16989017 12388444 17979934 15643279 18483878 16614059 18433785 12913760 10498854 18093676
MESH:D003643 Death Toluene 4.716431079
MESH:D016757 Death, Sudden, Cardiac Haloperidol 3.9620210726
MESH:D003704 Dementia Haloperidol 3.7211575062
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 9.2912868966 11906362 8156756 14531868 18759878 11298694 2524372 8970840
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 9.2912438553
MESH:D017449 Dermatitis, Allergic Contact Dinitrochlorobenzene 9.2915491423
MESH:D017449 Dermatitis, Allergic Contact Nickel 9.2917244072 17100760 19470301
MESH:D003876 Dermatitis, Atopic Diethylhexyl Phthalate 5.1216882537
MESH:D003876 Dermatitis, Atopic pirinixic acid 5.1218249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 6.622952479 3621924
MESH:D003877 Dermatitis, Contact Nickel 6.622952479
MESH:D017453 Dermatitis, Irritant JP8 aviation fuel 6.1617574719
MESH:D003920 Diabetes Mellitus Streptozocin 3.9116285004
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 9.6011751995 15331540 10990075
MESH:D003921 Diabetes Mellitus, Experimental Streptozocin 9.6019960420 19586609 7637645 18715473 16286809 8740154 19496084 17874149 12446591 15831366 2177838 1374869 15862027 6379147 16684804 11055810 18603373 17442507 19298542 12093613 15298345 11260395 12083368 12644472
MESH:D003921 Diabetes Mellitus, Experimental vanadyl sulfate 9.6016684804
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 4.6718772604
MESH:D003922 Diabetes Mellitus, Type 1 Streptozocin 4.6718603373
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 9.7316402076
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 9.7320387270
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 9.7316988119
MESH:D003924 Diabetes Mellitus, Type 2 Streptozocin 9.7319647726 19586609
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 9.7317107852
MESH:D058065 Diabetic Cardiomyopathies Streptozocin 4.7816025228
MESH:D003928 Diabetic Nephropathies Plant Extracts 6.9119706694
MESH:D003928 Diabetic Nephropathies Streptozocin 6.9119960420 19682444
MESH:D003929 Diabetic Neuropathies Progesterone 3.5717187935
MESH:D003930 Diabetic Retinopathy Streptozocin 4.5217662242
MESH:D003967 Diarrhea Dexamethasone 8.417237001
MESH:D003967 Diarrhea Dinoprostone 8.4111488427 7237001 10446763
MESH:D003967 Diarrhea Indomethacin 8.417907874 7237001
MESH:D006970 Disorders of Excessive Somnolence Clozapine 4.5915331141
MESH:D004314 Down Syndrome marker/mechanism 11771762
MESH:D056486 Drug-Induced Liver Injury 1-Naphthylisothiocyanate 35.977624871 17522070 20133375 18289764
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 35.9718551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 35.9716192314 1440618 18289764 6482804 18692083 9328219 9022650 11289319 18648102 9653073 6679447 7440962 8291058
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 35.9719085960 12705907 14986274 17522070 16227642 16109766 12958197 10915739 19420014 19739265 16177239 11287661 11834606 18071297 15619225 11461765 17562736 15968718 12153990 16081117 16781746 17906064 16393943 11421492 10774834 19416960 12594235 19164858 12540782 19370779 11743745 14725611 11739529 16485898 14550746 19923254 12392966 18713872 2444490 11529661 10663392
MESH:D056486 Drug-Induced Liver Injury bromobenzene 35.9712628495 10092053
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 35.979327722 19085960 2869522 6623471 21278145 19336974 16227642 10092053 17522070 7120509 7440962 15968718 4309450 11566570 7179309 3732212 10915739 15998439 15027814 3786805 16177239 6884620
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 35.9717654400
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 35.9719107877
MESH:D056486 Drug-Induced Liver Injury Diquat 35.9718445702 18164269
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 35.9716221962
MESH:D056486 Drug-Induced Liver Injury Gliotoxin 35.9719739265
MESH:D056486 Drug-Induced Liver Injury Ketoconazole 35.9718289764
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 35.9720420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 35.9712963478
MESH:D056486 Drug-Induced Liver Injury Trinitrotoluene 35.9721346803 18551238
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.1419426721
MESH:D004362 Drug Toxicity Cisplatin 5.6712231392 12649298 15033597 19839026
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 5.6711462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.2018043480 16133044 18446180 16326151 17190690 12774134
MESH:D004381 Duodenal Ulcer Indomethacin 3.2517329845 16699067 17151854 10671773 11535926 11991626 17045617 17351913 17202747 11595431 11595415
MESH:D050171 Dyslipidemias Clozapine 6.7516402076
MESH:D050171 Dyslipidemias Fenofibrate 6.7516707586
MESH:D004417 Dyspnea Chlorine 7.5120016425
MESH:D004417 Dyspnea Diazinon 7.5116487989
MESH:D004421 Dystonia Phenobarbital 3.121851702
MESH:D004485 Eczema Dexamethasone 3.5612438553
MESH:D004487 Edema Dexamethasone 19.7619703484
MESH:D004487 Edema Indomethacin 19.7619703484 16100529 8273558 7907874 10653021 8985016 7990266
MESH:D004487 Edema Mustard Gas 19.769260866 11402378 11428631 11428647
MESH:D004487 Edema perfluorooctanoic acid 19.7612083418 17259670
MESH:D004487 Edema pirinixic acid 19.7612083418
MESH:D004487 Edema Plant Extracts 19.7612787963
MESH:D004487 Edema Tetrachlorodibenzodioxin 19.7611000095 12711302
MESH:D004489 Edema, Cardiac 3,4,5,3',4'-pentachlorobiphenyl 15.5817686920
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 15.5815322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 15.5818230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 6.0612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 6.0617692515
MESH:D004701 Endocrine Gland Neoplasms decitabine 10.8419294695
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 10.8419294695
MESH:D016889 Endometrial Neoplasms Ethylenethiourea 8.777955072
MESH:D016889 Endometrial Neoplasms Fenofibrate 8.7716569247
MESH:D016889 Endometrial Neoplasms Tretinoin 8.7716569247
MESH:D004715 Endometriosis Indomethacin 10.4415652904
MESH:D004715 Endometriosis Progesterone 10.4416134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 10.4410568697 9294722
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 4.7215268973
MESH:D019446 Endotoxemia Indomethacin 3.5618509659
MESH:D004751 Enteritis Indomethacin 3.7910567023 17763956 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.0617980183
MESH:D004802 Eosinophilia Cyclophosphamide 6.2111006010
MESH:D004802 Eosinophilia Indomethacin 6.2111298111
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.193659116
MESH:D004828 Epilepsies, Partial Phenobarbital 2.923922381 11558140
MESH:D004827 Epilepsy Phenobarbital 4.9820417680
MESH:D004827 Epilepsy Plant Extracts 4.9819700373 19439326
MESH:D004832 Epilepsy, Absence Phenobarbital 2.736401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.337750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.083659116
MESH:D004890 Erythema Mustard Gas 4.219357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.1516302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 7.303581430
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 7.3016530937
MESH:D004938 Esophageal Neoplasms Cisplatin 7.3015173087 15464296 16785472 16481741 17638652
MESH:D004938 Esophageal Neoplasms Indomethacin 7.3011005569
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 6.3111564622
MESH:D005124 Eye Abnormalities Tretinoin 6.319664655 16938888
MESH:D005218 Fat Necrosis Thioacetamide 4.7616456712
MESH:D005234 Fatty Liver Carbon Tetrachloride 15.6812631006 19224547 12795759 61145 16239168 15959796 16045604 17595544
MESH:D005234 Fatty Liver Diethylnitrosamine 15.6820387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 15.6815345470
MESH:D005234 Fatty Liver pirinixic acid 15.6820131406 19236843
MESH:D005234 Fatty Liver Plant Extracts 15.6815975614
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.5411858732
MESH:D005317 Fetal Growth Retardation lead acetate 4.4819769572
MESH:D005334 Fever Dinoprostone 6.8816997862 11852909
MESH:D005334 Fever Indomethacin 6.8811852909 10431976 17627676
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.056705139
MESH:D005354 Fibrosarcoma Indomethacin 3.9510962813
MESH:D005355 Fibrosis Carbon Tetrachloride 18.1418705752
MESH:D005355 Fibrosis Indomethacin 18.1417994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 18.1420067830
MESH:D005355 Fibrosis Tretinoin 18.1417994277
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 18.1417994277
MESH:D005499 Folliculitis Indomethacin 4.2111298111
MESH:D005739 Gas Poisoning Chlorine 4.0520016425
MESH:D005756 Gastritis Acetaminophen 13.6616983495
MESH:D005756 Gastritis Diquat 13.6615046732
MESH:D005756 Gastritis Indomethacin 13.6615046732
MESH:D030342 Genetic Diseases, Inborn vinclozolin 3.9916973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.3416417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 3.7316452187
MESH:D005909 Glioblastoma Indomethacin 8.0212870263
MESH:D005909 Glioblastoma Tretinoin 8.0217312396
MESH:D005909 Glioblastoma trichostatin A 8.0218801729
MESH:D005910 Glioma Indomethacin 2.7516487511 18371953
MESH:D018316 Gliosarcoma Cyclophosphamide 4.5711389073
MESH:D005911 Gliosis Paraquat 4.2011124998
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.4911849393
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 8.537505956
MESH:D006042 Goiter perchlorate 8.5318801409
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.6310696789
MESH:D006073 Gout Indomethacin 4.4011248219
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.1111014644 16376943 15172196
MESH:D006261 Headache Nitroglycerin 4.2411284996 11554966
MESH:D006258 Head and Neck Neoplasms Cisplatin 12.6715464296 15102660
MESH:D006258 Head and Neck Neoplasms decitabine 12.6719215824
MESH:D006258 Head and Neck Neoplasms Indomethacin 12.6715482327
MESH:D006258 Head and Neck Neoplasms Tretinoin 12.6716096774
MESH:D034381 Hearing Loss Cisplatin 3.4719898482
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.1916084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.6115464296
MESH:D006330 Heart Defects, Congenital 3,4,5,3',4'-pentachlorobiphenyl 11.0417686920 20471113
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 11.0420471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.0410048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 11.049664655 14991402
MESH:D006331 Heart Diseases Streptozocin 3.5712093613
MESH:D006333 Heart Failure pirinixic acid 5.0220558911
MESH:D006333 Heart Failure Plant Extracts 5.0218097624
MESH:D006467 Hemophilia A Cyclophosphamide 4.3611918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.4711000095
MESH:D006486 Hemosiderosis 4-chloronitrobenzene 5.883710033
MESH:D006501 Hepatic Encephalopathy Indomethacin 8.0615633222
MESH:D006501 Hepatic Encephalopathy Thioacetamide 8.0618665440 15929193 17276928
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 4.5714986274
MESH:D006505 Hepatitis 1-Naphthylisothiocyanate 19.9118590720
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 19.916705139
MESH:D006505 Hepatitis Carbon Tetrachloride 19.9119110552 19900420
MESH:D006505 Hepatitis Diazinon 19.9116487989
MESH:D006505 Hepatitis Thioacetamide 19.9116456712
MESH:D019698 Hepatitis C, Chronic Indomethacin 3.7815135802
MESH:D006529 Hepatomegaly fumonisin B1 26.7216221962
MESH:D006529 Hepatomegaly perfluorooctanoic acid 26.723609246
MESH:D006529 Hepatomegaly Phenobarbital 26.7216109766
MESH:D006529 Hepatomegaly pirinixic acid 26.7218467677 16221962 19772884 19176532
MESH:D006529 Hepatomegaly propiconazole 26.7217178689 17178688
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 26.7215340226 16120746 12621046
MESH:D006529 Hepatomegaly Trinitrotoluene 26.7215817613
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.647520565
MESH:D006561 Herpes Simplex Plant Extracts 3.7010715843
MESH:D015658 HIV Infections beta Carotene 7.6216960176
MESH:D015658 HIV Infections Nickel 7.6217263646
MESH:D015658 HIV Infections Plant Extracts 7.6212878215
MESH:D006689 Hodgkin Disease Cisplatin 7.7116200630 16170182
MESH:D006689 Hodgkin Disease Cyclophosphamide 7.7117606976 16135485
MESH:D006689 Hodgkin Disease sodium arsenite 7.7112676792
MESH:D019584 Hot Flashes Plant Extracts 3.8016566672 14716179 17454163
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.0818606429 15340226 16959395 16354765 8697196
MESH:D006930 Hyperalgesia Acetaminophen 16.2616870215
MESH:D006930 Hyperalgesia Dinoprostone 16.2616793879
MESH:D006930 Hyperalgesia Indomethacin 16.2612727271
MESH:D006930 Hyperalgesia perfluorooctanoic acid 16.2612083418
MESH:D006930 Hyperalgesia Tretinoin 16.2616870215
MESH:D034321 Hyperamylasemia Indomethacin 4.7517883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.5916899240
MESH:D006940 Hyperemia Indomethacin 4.0612524144
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.6416778211
MESH:D006943 Hyperglycemia pirinixic acid 2.3520558911
MESH:D020138 Hyperhomocysteinemia Plant Extracts 3.6416484555
MESH:D006948 Hyperkinesis Clozapine 3.9716046005
MESH:D006949 Hyperlipidemias Indomethacin 6.7417546600
MESH:D006949 Hyperlipidemias Plant Extracts 6.7415268973 15975614
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.0215034207
MESH:D006967 Hypersensitivity Butylated Hydroxytoluene 3.6817604070
MESH:D006973 Hypertension Dexamethasone 3.6617042910
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 3.6618670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.1615338365
MESH:D007021 Hypospadias Ethinyl Estradiol 2.8816569931 16945680
MESH:D007077 Ileal Diseases Indomethacin 4.0618306037 10574470
MESH:D007079 Ileitis Indomethacin 4.4010651667 10647630 16133968
MESH:D007154 Immune System Diseases Cyclophosphamide 4.3716076520
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.4116133044
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.4815869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.5812013081
MESH:D007248 Infertility, Male Cyclophosphamide 29.2016517039 7193160
MESH:D007248 Infertility, Male decitabine 29.2017581917
MESH:D007248 Infertility, Male Diazinon 29.2012948887 16466525
MESH:D007248 Infertility, Male Diquat 29.204850670
MESH:D007248 Infertility, Male Ethinyl Estradiol 29.2017937319
MESH:D007248 Infertility, Male Paraquat 29.204850670
MESH:D007248 Infertility, Male sodium arsenite 29.2012646999 15346721
MESH:D007248 Infertility, Male Trinitrotoluene 29.2012150543
MESH:D007248 Infertility, Male vinclozolin 29.2016467254
MESH:D007249 Inflammation Dexamethasone 24.5811099482 8960868
MESH:D007249 Inflammation Diethylnitrosamine 24.5818785209
MESH:D007249 Inflammation Flavonoids 24.5817296493
MESH:D007249 Inflammation Indomethacin 24.587812673 12568917 3291741
MESH:D007249 Inflammation Mustard Gas 24.5811428620 11402378 9260866 11428647 17524151 16001271 9357497 11428631 8975870
MESH:D007249 Inflammation Nickel 24.5816166738
MESH:D007249 Inflammation perfluorooctanoic acid 24.5812083418
MESH:D007249 Inflammation Plant Extracts 24.5819332304 12787963 16366677 15997105
MESH:D007249 Inflammation Progesterone 24.5815869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 24.5812200463 12878042
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 3.0918200517
MESH:D007333 Insulin Resistance bisphenol A 5.0116393666
MESH:D007333 Insulin Resistance pirinixic acid 5.0116306350
MESH:D007410 Intestinal Diseases Indomethacin 15.9915831440 15610444 17329856 10210152 11713966 11686837 17994277 11855677 18236018
MESH:D007410 Intestinal Diseases rebamipide 15.9911686837
MESH:D007410 Intestinal Diseases Tretinoin 15.9917994277
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 15.9917994277
MESH:D007414 Intestinal Neoplasms Plant Extracts 3.7712628509 12351151 12584176
MESH:D019586 Intracranial Hypertension Indomethacin 4.4115241188
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.059022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.0616580747
MESH:D007569 Jaw Abnormalities Tretinoin 7.0615992940 17551590
MESH:D007579 Jejunal Diseases Indomethacin 4.0610574470 18306037 16133968
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.1815464296
MESH:D007674 Kidney Diseases Acetaminophen 15.6315629191 12587719
MESH:D007674 Kidney Diseases Bacitracin 15.6318289764
MESH:D007674 Kidney Diseases Cisplatin 15.6319839026 12649298 15190930 18289764 12231392
MESH:D007674 Kidney Diseases Indomethacin 15.6317190690
MESH:D007674 Kidney Diseases sodium arsenite 15.6320008137
MESH:D007674 Kidney Diseases Streptozocin 15.6312093613
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 3.4116518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 4.7316705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 4.736582329
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 3.8411231351
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 6.3012228301 10320625 11703811
MESH:D016773 Leishmaniasis, Cutaneous Ketoconazole 6.302166429 19744259 8889330 1311351
MESH:D007898 Leishmaniasis, Visceral Ketoconazole 3.7911332679
MESH:D007938 Leukemia Cyclophosphamide 7.2010602166
MESH:D007938 Leukemia decitabine 7.2018980019 19235587
MESH:D007938 Leukemia Tretinoin 7.2017143497
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 2.9917802794 17296974 17008537 17658394 18172266 18587576
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 6.2910373061
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 6.2910785260 15631656 16572323
MESH:D007951 Leukemia, Myeloid decitabine 6.7018454857 17236224 19117987
MESH:D007951 Leukemia, Myeloid Tretinoin 6.7016482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute decitabine 6.3517679729 18704418 18460780 18206229 19010910 19387464
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 6.3518360721
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 6.3516294345 17596541 19850784
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 6.3518206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.5018055864
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.4717712046 17217047 17361223 19029980 17294898 16891316 16788101 17506722 17339181 16766008 19075265 12679006 19642359 17301526 17649720 16140955 16823087 16935935 17107899 17368321 16331271 19225113 9834237 19035177 15748426
MESH:D007964 Leukocytosis Indomethacin 4.4116537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 4.7517980183
MESH:D007970 Leukopenia Cyclophosphamide 4.0210052129 11830472
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 9.808812269
MESH:D007984 Leydig Cell Tumor vinclozolin 9.8016417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 2.589224671
MESH:D008064 Lipidoses Clozapine 6.1517567588
MESH:D008064 Lipidoses Ketoconazole 6.1517567588
MESH:D008101 Liver Abscess, Amebic Indomethacin 4.7511479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.6711408273 16943688 17157831 11903743 21278145 16221502 17334410 16239168 17174718
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.6718522880 18407596 20032147 19638242 18665156
MESH:D008103 Liver Cirrhosis Phenobarbital 10.6721047994
MESH:D008103 Liver Cirrhosis Plant Extracts 10.6717157831
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.529327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 19.9617698563 10355542 12666154 12667390 14716496 18166357 15730626 17721639 17761835 18187930 18205269 18339082 14748882 18481824 13678700 15362042 12445418 15123356 17823541 17640975 17869086 17766677 12389079 15876570 12546737 17525996 14512876 17631135 17557913 16192424 17805973 12632512 15931870 17565644 18376398 18279442 17708605 17944888 16136751 16011737 18412020 18317297 15925388 18429990 15338365 18263696 16248980 15057751 15818738 18705752 18210741 15893842 17922224 16116963 15370692 15650968 18472332 18156304 18006644 15052691 16015684 12958196 12632514 15996030 12898905 12445421 16638106 15959796 17481882 16027843 18251166 12741479 15673190 18418968 18054572 12586293 17714472 17976157 18395914 18277467 14620537 16097048 18395095 17900296 20821823 12609069 16033810 12649538 18472094 18420326 14724832 14716833 11481614
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 19.9616718785
MESH:D008106 Liver Cirrhosis, Experimental Dicarbethoxydihydrocollidine 19.9616015684
MESH:D008106 Liver Cirrhosis, Experimental Dinoprostone 19.9615816358
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 19.9617481882
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 19.9615474484
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 19.9618194892
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 19.9615474484
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 19.9615479170
MESH:D008106 Liver Cirrhosis, Experimental S-Adenosylmethionine 19.9615983038
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 19.9612878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 19.9615465738 15158331 18263696 18032466 15288473 15474484 18615449 15316131 12085344 15716488 14739098 18295389 15362042 15078482 12175628 18380797 12891558 16097051 17127702 18458672 15334695 17629604 16511523 16126171 10677585 17292413 16098781 16248980 18606216 16343077 12557150 11682029 12679928 17355460 15095483 16489207 12531686 15288472 18395095 18031379 11481614 11172339 15075984 18416461 17050028
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 19.9618397230 16248980
MESH:D008107 Liver Diseases 1-Naphthylisothiocyanate 22.2017184895
MESH:D008107 Liver Diseases Acetaminophen 22.2011587558 19784758 16611625 19460945 16610002 19014921 12587719 12969438
MESH:D008107 Liver Diseases Carbon Tetrachloride 22.2015720792 17285989 16246199 16964402 15830285
MESH:D008107 Liver Diseases Chlorpyrifos 22.2015991261
MESH:D008107 Liver Diseases Diethylnitrosamine 22.2017034775
MESH:D008107 Liver Diseases Dinoprostone 22.2015816358
MESH:D008107 Liver Diseases Phenobarbital 22.2019363144
MESH:D008107 Liver Diseases Plant Extracts 22.2017034775
MESH:D008107 Liver Diseases propiconazole 22.2019363144
MESH:D008107 Liver Diseases Thioacetamide 22.2018374380 16337175 15158337
MESH:D017093 Liver Failure Carbon Tetrachloride 3.2415123358
MESH:D017114 Liver Failure, Acute Acetaminophen 11.3816871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 11.3816899240 14706259
MESH:D017114 Liver Failure, Acute Thioacetamide 11.3815633222 12479984 15313186 17276928
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 52.3421137059 20195826
MESH:D008113 Liver Neoplasms Butylated Hydroxytoluene 52.3418177683
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 52.3419294768
MESH:D008113 Liver Neoplasms Clofibric Acid 52.3417602206
MESH:D008113 Liver Neoplasms dicyclanil 52.3420118626
MESH:D008113 Liver Neoplasms Diethylhexyl Phthalate 52.3411940454
MESH:D008113 Liver Neoplasms Diethylnitrosamine 52.3412771043 19850985 19833225 2422723 16942905 21047994 19427195 19642983 20137499 21167192 19073162 21071580 19690152 19551842 18754104 2862719 19294768 15885732 21278145 20405173 19499222 19090486 19254457 20492335 20101389 10737359 19638242 20583210 19812893 19256749 18648771 9163691 20118626 19996281 19426721 20434301 18644402 19255062 15175105 12112319 18978307 20501860 20452335 18977376
MESH:D008113 Liver Neoplasms Epoxy Compounds 52.3412562636
MESH:D008113 Liver Neoplasms Ethylenethiourea 52.3411940454
MESH:D008113 Liver Neoplasms Fenofibrate 52.3418978307
MESH:D008113 Liver Neoplasms Methapyrilene 52.3415890375
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 52.3414757943 18709148
MESH:D008113 Liver Neoplasms Phenobarbital 52.348742319 19812893 19482888 19073162 15975961 21047994
MESH:D008113 Liver Neoplasms pirinixic acid 52.3416377806 15890375 20007298
MESH:D008113 Liver Neoplasms Plant Extracts 52.3419168119
MESH:D008113 Liver Neoplasms propiconazole 52.3419028983
MESH:D008113 Liver Neoplasms sodium arsenite 52.3415276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 52.3416984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 32.756587162 598648 3712494 1399818
MESH:D008114 Liver Neoplasms, Experimental beta Carotene 32.7517113696
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 32.7515583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 32.7518544905 19126423 18079962 18093689 16267830 3124819 19009564 2563599 18775883 18308698 19539802 16842330 17174075 9362446 17942915 19004024 18253720 18164116 17854601 18282651 21159647 19519916
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 32.7518775883 18253720
MESH:D008114 Liver Neoplasms, Experimental Hexachlorobenzene 32.751423854
MESH:D008114 Liver Neoplasms, Experimental kojic acid 32.7518544905
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 32.7517172636 6150874 1399818 2563599 18308698
MESH:D008114 Liver Neoplasms, Experimental propiconazole 32.7517178689
MESH:D008114 Liver Neoplasms, Experimental styrene oxide 32.7512562636
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 32.7512151625
MESH:D008171 Lung Diseases Mustard Gas 8.3018702808 18161513
MESH:D008171 Lung Diseases Ozone 8.308266340 19066396
MESH:D008171 Lung Diseases sodium arsenite 8.3019095001
MESH:D055370 Lung Injury naphthalene 6.586834280
MESH:D055370 Lung Injury Ozone 6.5820417186
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 19.6018816296 20869020 18569708 20135361 20464547 20064080 17053015 18520028 6695378
MESH:D008175 Lung Neoplasms beta Carotene 19.6016401635
MESH:D008175 Lung Neoplasms Butylated Hydroxytoluene 19.6019359593 18597497 16337739 19925653 11246140 15390079 11696405
MESH:D008175 Lung Neoplasms Cisplatin 19.6017225452 11798837 6189445
MESH:D008175 Lung Neoplasms Dexamethasone 19.6011195469 15824018
MESH:D008175 Lung Neoplasms Diethylnitrosamine 19.6020970405 20512841 21163286 6695378
MESH:D008175 Lung Neoplasms Epoxy Compounds 19.6012562636
MESH:D008175 Lung Neoplasms Indomethacin 19.6011497255 16537180 11053908
MESH:D008175 Lung Neoplasms Mustard Gas 19.608781369 3148597
MESH:D008175 Lung Neoplasms Ozone 19.607614698 8597069
MESH:D008175 Lung Neoplasms Plant Extracts 19.6020869020
MESH:D008175 Lung Neoplasms sodium arsenite 19.6016712894 15276417 17306315 19931552 17077188
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 19.6011884234 19555203
MESH:D008223 Lymphoma Cyclophosphamide 5.4312854902
MESH:D008223 Lymphoma decitabine 5.4319470736
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 3.7216675587
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 3.3711911406
MESH:D008325 Mammary Neoplasms, Experimental Butylated Hydroxytoluene 8.891500032
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 8.8912807724
MESH:D008325 Mammary Neoplasms, Experimental methyleugenol 8.8911921183
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 8.8911408345 17203775
MESH:D008527 Medulloblastoma Tretinoin 2.3017453147
MESH:D008545 Melanoma Cisplatin 10.9218332650 16432458 12883367 18505091 11135225 16809738 12393984 17023156 18176117 17761969 16248763 15577323 12374674
MESH:D008545 Melanoma decitabine 10.9217785578 16505122
MESH:D008545 Melanoma Dinitrochlorobenzene 10.9212202904 17334785
MESH:D008545 Melanoma epigallocatechin gallate 10.9211746506 17992120
MESH:D008545 Melanoma sodium arsenite 10.9216487513 19082730
MESH:D008545 Melanoma Tretinoin 10.9216752155
MESH:D008545 Melanoma trichostatin A 10.9216505122
MESH:D018328 Melanoma, Amelanotic Cisplatin 3.8315990972
MESH:D008546 Melanoma, Experimental Acetaminophen 7.7719513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 7.7716388313
MESH:D008591 Meningomyelocele Tretinoin 3.5016940565
MESH:D001523 Mental Disorders Clozapine 5.3316856516
MESH:D001523 Mental Disorders Haloperidol 5.3316856516
MESH:D008607 Mental Retardation Toluene 3.239294310
MESH:D008654 Mesothelioma Cisplatin 2.7717638057
MESH:D024821 Metabolic Syndrome X Clozapine 3.6019142101
MESH:D008679 Metaplasia Ozone 4.1410496685
MESH:D008708 Methemoglobinemia 4-chloronitrobenzene 7.403710033
MESH:D008708 Methemoglobinemia Nitroglycerin 7.403537620
MESH:D008881 Migraine Disorders Indomethacin 2.9611903285
MESH:D020326 Migraine without Aura Dinoprostone 8.2111304026
MESH:D020326 Migraine without Aura Nitroglycerin 8.2114659530
MESH:D019957 Motor Skills Disorders Toluene 4.359294310
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 6.0916381670
MESH:D009062 Mouth Neoplasms Indomethacin 6.0912636206
MESH:D009101 Multiple Myeloma decitabine 8.0518172295
MESH:D009101 Multiple Myeloma Dexamethasone 8.0515867202 15744524 16118317
MESH:D009101 Multiple Myeloma trichostatin A 8.0518172295
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 4.5517962980
MESH:D009135 Muscular Diseases Glucocorticoids 7.8515946989
MESH:D009135 Muscular Diseases pirinixic acid 7.8516239165
MESH:D009190 Myelodysplastic Syndromes decitabine 8.6816882708 18608210 19157545 19010910
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 8.689809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 8.6817596541
MESH:D009203 Myocardial Infarction Nitroglycerin 4.3114729435
MESH:D009203 Myocardial Infarction pirinixic acid 4.3119151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.2312213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.1816411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.5317484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 7.5618551238
MESH:D009336 Necrosis Trinitrotoluene 7.5618551238
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 6.603581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 6.603581430 9029167
MESH:D009362 Neoplasm Metastasis Indomethacin 6.6016537180 11239499 11053908
MESH:D009369 Neoplasms Benzo(a)pyrene 18.2311141357
MESH:D009369 Neoplasms beta Carotene 18.2317051425
MESH:D009369 Neoplasms Cisplatin 18.2316773208
MESH:D009369 Neoplasms Cyclophosphamide 18.2318854779
MESH:D009369 Neoplasms decitabine 18.2319116145 19470736 17925555
MESH:D009369 Neoplasms pirinixic acid 18.2317405874
MESH:D009369 Neoplasms sodium arsenite 18.2311559025
MESH:D009369 Neoplasms Tretinoin 18.2316594593 16946489
MESH:D009374 Neoplasms, Experimental Indomethacin 6.2410663608 15625704
MESH:D009374 Neoplasms, Experimental sodium arsenite 6.2420056578
MESH:D009395 Nephritis, Interstitial Cisplatin 3.5415464296
MESH:D009410 Nerve Degeneration Paraquat 2.9516893418
MESH:D009421 Nervous System Malformations bisphenol A 11.1811399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 11.1814600291
MESH:D009421 Nervous System Malformations Tretinoin 11.189125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 8.106679447
MESH:D009436 Neural Tube Defects sodium arsenite 8.1012854658
MESH:D009436 Neural Tube Defects Tretinoin 8.109142499
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 4.2617168769
MESH:D009447 Neuroblastoma Cisplatin 5.298761367
MESH:D009447 Neuroblastoma Cyclophosphamide 5.2916115947 8761367 15176712
MESH:D019636 Neurodegenerative Diseases Acetaminophen 9.4318514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 9.4320387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 9.4312349958
MESH:D017599 Neuroectodermal Tumors Cisplatin 8.408761367
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 8.4012837982 8761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.1520387270
MESH:D020258 Neurotoxicity Syndromes Chlorpyrifos 3.4615081274
MESH:D009503 Neutropenia Cyclophosphamide 6.628291058
MESH:D009503 Neutropenia Mustard Gas 6.627688884 16761898
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.039802331
MESH:D009765 Obesity Clozapine 5.4419142110 18515891
MESH:D009765 Obesity pirinixic acid 5.4420558911
MESH:D009765 Obesity Plant Extracts 5.4420132043 19056576
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.216374098
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 10.3312819281 16049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 10.336482804 4026338
MESH:D009784 Occupational Diseases Trinitrotoluene 10.3312819281 14694615 17852074
MESH:D009845 Oligospermia Cyclophosphamide 3.7716517039
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.053988306
MESH:D010003 Osteoarthritis Indomethacin 3.027009135
MESH:D010005 Osteoarthropathy, Secondary Hypertrophic Dinoprostone 5.5118500342
MESH:D010018 Osteomalacia Phenobarbital 3.4217016548
MESH:D010049 Ovarian Diseases bisphenol A 4.0411985600
MESH:D010051 Ovarian Neoplasms Cisplatin 13.246897625 19769630 15464296 17225452
MESH:D010051 Ovarian Neoplasms decitabine 13.2419259094 19331143
MESH:D010051 Ovarian Neoplasms Progesterone 13.2417393432 16525653
MESH:D010051 Ovarian Neoplasms sodium arsenite 13.2417306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 13.2416936753
MESH:D010051 Ovarian Neoplasms trichostatin A 13.2419331143
MESH:D010146 Pain Acetaminophen 9.6816870215
MESH:D010146 Pain Cyclophosphamide 9.6812161096 18093676
MESH:D010146 Pain Indomethacin 9.683291741 17627676 13679232 17440234
MESH:D010146 Pain Tretinoin 9.6816870215
MESH:D010149 Pain, Postoperative Indomethacin 3.7212538197 18702446
MESH:D010190 Pancreatic Neoplasms Cisplatin 17.6219003803
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 17.6211332152
MESH:D010190 Pancreatic Neoplasms decitabine 17.6219294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 17.6216540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 17.6216965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 17.6215976015
MESH:D010190 Pancreatic Neoplasms trichostatin A 17.6219294695
MESH:D010195 Pancreatitis Indomethacin 5.9415028970 17883296
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 5.9417698068
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.8011578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 14.777296757
MESH:D010212 Papilloma cumene hydroperoxide 14.7717234724 12065085
MESH:D010212 Papilloma Hydrogen Peroxide 14.7712065085
MESH:D010212 Papilloma Plant Extracts 14.7716517061 15173996
MESH:D010257 Paraneoplastic Syndromes Indomethacin 4.7516537180
MESH:D010300 Parkinson Disease Eugenol 4.5417329831
MESH:D010300 Parkinson Disease Paraquat 4.5411181820 15451049 15824117 12911755 16140633 16510128 11124998 11445065
MESH:D010302 Parkinson Disease, Secondary Paraquat 3.5116190885
MESH:D020734 Parkinsonian Disorders Indomethacin 3.2812349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 4.7511903285
MESH:D010382 Peliosis Hepatis 1-Naphthylisothiocyanate 10.6020133375
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 10.6012520081
MESH:D010437 Peptic Ulcer Indomethacin 4.2011148446
MESH:D010518 Periodontitis Indomethacin 3.9517225004
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.4115464296
MESH:D010538 Peritonitis Ozone 3.2216369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 9.816228378
MESH:D010787 Photosensitivity Disorders 4-hydroxy-2-nonenal 9.8111550810
MESH:D010997 Pleural Neoplasms Cisplatin 4.3817638057
MESH:D011014 Pneumonia Butylated Hydroxytoluene 18.9611893704
MESH:D011014 Pneumonia Epoxy Compounds 18.9612504350
MESH:D011014 Pneumonia Ozone 18.9618929643 18007984 18381685
MESH:D011014 Pneumonia Paraquat 18.9612504350
MESH:D011041 Poisoning Diazinon 6.1217603234
MESH:D011041 Poisoning Mustard Gas 6.1215727166
MESH:D017119 Porphyria Cutanea Tarda Hexachlorobenzene 8.109918132
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 8.1018163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 6.352563599
MESH:D011230 Precancerous Conditions Phenobarbital 6.352563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 5.7121297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 5.7121297632
MESH:D047928 Premature Birth Indomethacin 4.2017000239
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 15.6310548101
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 15.6317132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 15.6311896295 11118676 11222880 11399792
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 15.6318042343 18220299 19015723
MESH:D055728 Primary Myelofibrosis decitabine 9.3517616702
MESH:D055728 Primary Myelofibrosis trichostatin A 9.3517616702
MESH:D011469 Prostatic Diseases vinclozolin 3.9918220299
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 3.3420887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.9217292933
MESH:D011471 Prostatic Neoplasms bisphenol A 1.9216740699
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 1.9217136230
MESH:D011471 Prostatic Neoplasms Ketoconazole 1.9217404083
MESH:D011471 Prostatic Neoplasms Plant Extracts 1.9214666653 17804756
MESH:D011471 Prostatic Neoplasms sodium arsenite 1.9216039940
MESH:D011471 Prostatic Neoplasms trichostatin A 1.9218798265 19789329
MESH:D011472 Prostatitis vinclozolin 3.9918629315
MESH:D011507 Proteinuria Indomethacin 6.4211849393
MESH:D011507 Proteinuria Tretinoin 6.4216636307
MESH:D011537 Pruritus Ethinyl Estradiol 6.4215861022 16919318
MESH:D011537 Pruritus Mustard Gas 6.4218058305
MESH:D019310 Pseudolymphoma Phenobarbital 3.5312752131
MESH:D011595 Psychomotor Agitation Haloperidol 4.0311575062
MESH:D011618 Psychotic Disorders Clozapine 6.6815331141
MESH:D011618 Psychotic Disorders Haloperidol 6.6811575062
MESH:D011625 Pterygium Tretinoin 3.8516723453
MESH:D011629 Puberty, Precocious bisphenol A 3.8410548101
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 6.5416636934
MESH:D011658 Pulmonary Fibrosis Mustard Gas 6.5417266442 17720292 17894541 17620002 10334151
MESH:D011658 Pulmonary Fibrosis Paraquat 6.5417997886 16324872
MESH:D051437 Renal Insufficiency Cisplatin 3.4915464296
MESH:D015427 Reperfusion Injury pirinixic acid 1.8319058328
MESH:D012120 Respiration Disorders Chlorine 4.2518579056
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 6.3518379247 11700416
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 6.3511700416
MESH:D012135 Respiratory Sounds Chlorpyrifos 6.9016611668 17119214 11874814
MESH:D012135 Respiratory Sounds Paraquat 6.9011874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 2.9318990726
MESH:D012140 Respiratory Tract Diseases Chlorpyrifos 3.9416611668 17119214
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 6.393692021
MESH:D012162 Retinal Degeneration Paraquat 6.3916458197
MESH:D012208 Rhabdomyosarcoma decitabine 8.0119155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 8.0116283617 16116481
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.4118045962
MESH:D012512 Sarcoma, Ewing's Cisplatin 3.5314601052
MESH:D012559 Schizophrenia Clozapine 3.3216141801 20521326 18806925 17726453 20168265 20107430 19369910 20580759 17667964 20452607 17123785 18855531 20521320 11763009 11151749
MESH:D012559 Schizophrenia Haloperidol 3.3218513383 19369910 1830565 20107430
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 3.9416636934
MESH:D012640 Seizures 2,4-dinitrotoluene 8.4018551238
MESH:D012640 Seizures Phenobarbital 8.403137016 4039156 11442880 16876388
MESH:D012640 Seizures Toluene 8.406431079 9294310
MESH:D012640 Seizures Trinitrotoluene 8.4018551238
MESH:D003294 Seizures, Febrile Phenobarbital 3.876407741
MESH:D012729 Sex Chromosome Aberrations Chlorpyrifos 5.126418539
MESH:D012871 Skin Diseases Mustard Gas 2.3815451306 12880345 16961503
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 22.1810029692 19755658
MESH:D012878 Skin Neoplasms cumene hydroperoxide 22.188532709 12065085 17234724
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 22.1812065085
MESH:D012878 Skin Neoplasms Plant Extracts 22.1815173996 16517061
MESH:D012878 Skin Neoplasms sodium arsenite 22.1819524636 18572023
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 22.188532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 22.1816192470
MESH:D012878 Skin Neoplasms Tretinoin 22.1816467112
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.3815464296
MESH:D013088 Spermatocele Ethinyl Estradiol 2.9816709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 4.5716517039
MESH:D013119 Spinal Cord Injuries Progesterone 3.3415862959 16503802
MESH:D016135 Spinal Dysraphism sodium arsenite 3.0212854658
MESH:D013163 Splenomegaly Trinitrotoluene 4.2715817613
MESH:D013272 Stomach Diseases beta Carotene 16.6917638125
MESH:D013272 Stomach Diseases Dexamethasone 16.6915472012
MESH:D013272 Stomach Diseases Indomethacin 16.6916280098 17160473 18545984 15038085 18209964 15472012 10486359 17207306 16184426 10192188 17638125 10215738 16113693
MESH:D013272 Stomach Diseases rebamipide 16.6916184426
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 13.202093021 20155912
MESH:D013274 Stomach Neoplasms Butylated Hydroxyanisole 13.201399818 3581430
MESH:D013274 Stomach Neoplasms Cisplatin 13.2018396642 15958060 17522103
MESH:D013274 Stomach Neoplasms decitabine 13.2019037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 13.2018456281
MESH:D013274 Stomach Neoplasms Epoxy Compounds 13.2012562636
MESH:D013274 Stomach Neoplasms Indomethacin 13.2015609394
MESH:D013274 Stomach Neoplasms rebamipide 13.2015993841
MESH:D013274 Stomach Neoplasms styrene oxide 13.2012562636
MESH:D013274 Stomach Neoplasms Tretinoin 13.2017261132
MESH:D013276 Stomach Ulcer beta Carotene 13.6912500499
MESH:D013276 Stomach Ulcer Dexamethasone 13.6915138204
MESH:D013276 Stomach Ulcer Eugenol 13.6918543354
MESH:D013276 Stomach Ulcer Indomethacin 13.6915255614 16755016 16934674 11595431 18237397 17977527 17657623 10878458 18193104 17895592 11595415 18431645 16252198 10423059 18181030 16631530 12500499 10750652 12787963 18209962 16169175 17627676 11523592 17918041 17654042 16150113 18726076 11906479 14567935 15104355 18299717 12077510 18087811 16397915 12467913 18543354 11145282 1323529 11729361 17135157 12498302 15138204
MESH:D013276 Stomach Ulcer Plant Extracts 13.6917135157 12787963 18193104 15255614 18237397
MESH:D019966 Substance-Related Disorders bisphenol A 3.0516045194 16684133
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 4.1112837982
MESH:D017180 Tachycardia, Ventricular Haloperidol 3.8120210726
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 4.5217997062
MESH:D013733 Testicular Diseases Toluene 4.0210514026 10048760
MESH:D013736 Testicular Neoplasms Cisplatin 3.7415464296 17225452
MESH:D013921 Thrombocytopenia 1-Naphthylisothiocyanate 3.9120133375
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.7411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.3315669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 2.9412697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 26.337505956 6582329 3712494 6587162 1399818
MESH:D013964 Thyroid Neoplasms Butyrates 26.3317967635
MESH:D013964 Thyroid Neoplasms decitabine 26.3317967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 26.337505956
MESH:D013964 Thyroid Neoplasms Ethylenethiourea 26.3311940454
MESH:D013964 Thyroid Neoplasms Indomethacin 26.3318791128 14736730 11352223
MESH:D013964 Thyroid Neoplasms Phenobarbital 26.331399818
MESH:D013964 Thyroid Neoplasms Tretinoin 26.3316026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 2.9416051514
MESH:D014376 Tuberculosis Tretinoin 2.5616040207
MESH:D014456 Ulcer Indomethacin 3.9517380554 10574470
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 19.7216049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 19.728074119
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 19.7217053015
MESH:D001749 Urinary Bladder Neoplasms Butylated Hydroxyanisole 19.721399818
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 19.7212973940 15464296 17225452
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 19.7214692829
MESH:D001749 Urinary Bladder Neoplasms decitabine 19.7219087683 17616700
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 19.7216452187 16712894 11723127 17306315
MESH:D014570 Urologic Diseases Diazinon 4.3216487989
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.3710091137
MESH:D014581 Urticaria Acetaminophen 2.1110982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 11.0416803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 11.0411813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 11.0416129372
MESH:D014591 Uterine Diseases bisphenol A 4.0414652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.4114692618
MESH:D014604 Uveal Neoplasms decitabine 9.6417785578
MESH:D014604 Uveal Neoplasms Tretinoin 9.6416752155
MESH:D014605 Uveitis Dexamethasone 3.861336536
MESH:D014625 Vaginal Neoplasms Cisplatin 3.6915577323
MESH:D014652 Vascular Diseases sodium arsenite 3.4817056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.6312125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.6714671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 3.8318097624
MESH:D020257 Ventricular Remodeling Plant Extracts 4.3718097624
MESH:D014820 Vitiligo Tretinoin 3.1516761959
MESH:D014839 Vomiting Cisplatin 8.3511897121
MESH:D014839 Vomiting Indomethacin 8.3511897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.2815886252
MESH:D015430 Weight Gain Clozapine 3.6420564506 20107430 16402076 17502770 16141801 20521320
MESH:D015431 Weight Loss Clozapine 4.1317933447
MESH:D009396 Wilms Tumor Tretinoin 3.1416287080
MESH:D014947 Wounds and Injuries Plant Extracts 3.4620213670 19894650
Pathway ID Pathway Name
KEGG:00982 Drug metabolism - cytochrome P450
KEGG:00480 Glutathione metabolism
KEGG:00980 Metabolism of xenobiotics by cytochrome P450
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA29023
    • No data
    Releated disease ID Related disease Name
    PA443265Adenocarcinoma
    PA446661Carcinoma, Small Cell
    PA443626Carcinoma, Squamous Cell
    PA444818Lung Neoplasms
    PA446680Neoplasms, Squamous Cell
    Releated drug ID Related drug Name
    PA449014cisplatin
    PA448691busulfan
    PA449396dopamine
    PA449470epinephrine
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00143 - BSS Plus Dietary supplement;Micronutrient
    DB02458 - Glutathione S-(2,4 Dinitrobenzene)
    DB03310 - Oxidized Glutathione Disulfide
    DB04701 - S-METHYL-GLUTATHIONE
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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