AutismKB 2.0

Annotation Detail for GSTM3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GSTM3 ( GST5,GSTB,GSTM3-3,GTM3,MGC3310,MGC3704 )
Gene Full Name: glutathione S-transferase mu 3 (brain)
Band: 1p13.3
Quick LinksEntrez ID:2947; OMIM: 138390; Uniprot ID:GSTM3_HUMAN; ENSEMBL ID: ENSG00000134202; HGNC ID: 4635
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-4061glutathione-mediated detoxification
Pathway IDPathway Name
hsa00480Glutathione metabolism
hsa00980Metabolism of xenobiotics by cytochrome P450
hsa00982Drug metabolism - cytochrome P450
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1739Oral cancer
1848Embryoma
2020Gallbaldder cancer
2022Liver cancer
Desease Name
cystic fibrosis
colorectal cancer
prostate cancer
CANCER
Asthma
breast cancer
IMMUNE
lung cancer
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C028328 1,2-dichloro-4-nitrobenzene GSTM3 protein affects the metabolism of 1,2-dichloro-4-nitrobenzeneaffects metabolic processing 3169012
C042630 1-chloro-2,4-dinitrobenzene-glutathione conjugate GSTM3 protein affects the metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugateaffects metabolic processing 11684093
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of GSTM3 mRNAaffects expression 21346803
C009497 2-(4-toluidino)-6-naphthalenesulfonic acid 2-(4-toluidino)-6-naphthalenesulfonic acid binds to GSTM3 proteinaffects binding 7725348
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of GSTM3 mRNAaffects expression 21346803
C013166 2-nonenal GSTM3 protein polymorphism results in decreased metabolism of 2-nonenaldecreases metabolic processing 15247628
C013166 2-nonenal GSTM3 protein polymorphism results in increased metabolism of 2-nonenalincreases metabolic processing 15247628
C027576 4-hydroxy-2-nonenal [GSTM1 protein binds to GSTM3 protein] which affects the metabolism of 4-hydroxy-2-nonenal analogaffects binding|affects metabolic processing 11256969
D000082 Acetaminophen Acetaminophen results in decreased expression of GSTM3 mRNAdecreases expression 16611625
D000082 Acetaminophen Acetaminophen results in decreased expression of GSTM3 mRNAdecreases expression 17522070
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GSTM3 mRNAaffects expression 16483693
D001151 Arsenic Arsenic results in increased expression of GSTM3 mRNAincreases expression 19945496
D001194 Asbestos Asbestos affects the expression of GSTM3 proteinaffects expression 7614465
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of GSTM3 mRNAincreases expression 20064835
D002083 Butylated Hydroxyanisole Butylated Hydroxyanisole results in increased expression of GSTM3 mRNAincreases expression 6822548
D002083 Butylated Hydroxyanisole Butylated Hydroxyanisole results in increased expression of GSTM3 proteinincreases expression 11991805
D002251 Carbon Tetrachloride PLG gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of GSTM3 mRNA]increases expression|increases reaction 16006527
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of GSTM3 mRNAdecreases expression 17522070
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of GSTM3 mRNAincreases expression 16239168
D002259 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GSTM3 mRNAdecreases expression 16039398
D002330 Carmustine GSTM3 protein affects the metabolism of Carmustineaffects metabolic processing 15247628
D002330 Carmustine GSTM3 protein results in decreased nitrosation of and results in decreased activity of Carmustinedecreases activity|decreases nitrosation 8395980
D002725 Chloroform Chloroform results in decreased expression of GSTM3 mRNAdecreases expression 17522070
D004390 Chlorpyrifos Chlorpyrifos results in decreased expression of GSTM3 mRNAdecreases expression 17452286
D019826 Cholic Acid Cholic Acid results in increased expression of GSTM3 mRNAincreases expression 17521389
D002995 Clofibric Acid Clofibric Acid affects the expression of GSTM3 mRNAaffects expression 17602206
D003300 Copper [Copper co-treated with Diethylnitrosamine co-treated with Iron] results in increased expression of GSTM3 mRNAaffects cotreatment|increases expression 20302851
D003300 Copper [Copper co-treated with Diethylnitrosamine] results in increased expression of GSTM3 mRNAaffects cotreatment|increases expression 20302851
C007164 cumene hydroperoxide GSTM3 protein polymorphism results in decreased metabolism of cumene hydroperoxidedecreases metabolic processing 15247628
C007164 cumene hydroperoxide GSTM3 protein polymorphism results in increased metabolism of cumene hydroperoxideincreases metabolic processing 15247628
C007164 cumene hydroperoxide GSTM3 protein affects the metabolism of cumene hydroperoxideaffects metabolic processing 11684093
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of GSTM3 mRNAincreases expression 17654400
C014347 decitabine [decitabine affects the methylation of GSTM3 promoter] which affects the expression of GSTM3 mRNAaffects expression|affects methylation 18664505
D003907 Dexamethasone Dexamethasone results in decreased expression of GSTM3 mRNAdecreases expression 17522070
D003976 Diazinon Diazinon results in decreased expression of GSTM3 mRNAdecreases expression 19440498
17452286
C061481 dibenzoylmethane dibenzoylmethane results in increased expression of GSTM3 mRNAincreases expression 17942926
C061481 dibenzoylmethane [sulforafan co-treated with dibenzoylmethane] results in increased expression of GSTM3 mRNAaffects cotreatment|increases expression 17942926
D002945 Cisplatin GSTM3 gene polymorphism affects the susceptibility to Cisplatinaffects response to substance 11081456
D002945 Cisplatin GSTM3 protein affects the susceptibility to Cisplatinaffects response to substance 16217747
C121718 dicyclanil dicyclanil results in increased expression of GSTM3 mRNAincreases expression 15664270
D004026 Dieldrin Dieldrin affects the expression of GSTM3 mRNAaffects expression 19440498
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM3 mRNAaffects cotreatment|increases expression 17917374
D004052 Diethylnitrosamine [Copper co-treated with Diethylnitrosamine co-treated with Iron] results in increased expression of GSTM3 mRNAaffects cotreatment|increases expression 20302851
D004052 Diethylnitrosamine [Copper co-treated with Diethylnitrosamine] results in increased expression of GSTM3 mRNAaffects cotreatment|increases expression 20302851
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNAaffects cotreatment|decreases expression 18544905
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM3 mRNAaffects cotreatment|increases expression 18544905
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of GSTM3 mRNAdecreases expression 19638242
D004052 Diethylnitrosamine [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNAaffects cotreatment|decreases expression 18775883
18253720
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of GSTM3 mRNAincreases expression 11331657
D004137 Dinitrochlorobenzene GSTM3 protein affects the metabolism of Dinitrochlorobenzeneaffects metabolic processing 9545290
D004137 Dinitrochlorobenzene GSTM3 protein polymorphism results in decreased metabolism of Dinitrochlorobenzenedecreases metabolic processing 15247628
D004137 Dinitrochlorobenzene GSTM3 protein polymorphism results in increased metabolism of Dinitrochlorobenzeneincreases metabolic processing 15247628
D004137 Dinitrochlorobenzene Dinitrochlorobenzene results in increased expression of GSTM3 proteinincreases expression 9794801
D004137 Dinitrochlorobenzene GSTM3 protein affects the metabolism of Dinitrochlorobenzeneaffects metabolic processing 3169012
D004281 Docosahexaenoic Acids PPARA protein promotes the reaction [Docosahexaenoic Acids results in increased expression of GSTM3 mRNA]increases expression|increases reaction 18489776
D004391 Dust Dust results in increased expression of GSTM3 mRNAincreases expression 17805423
D015118 Eicosapentaenoic Acid PPARA protein promotes the reaction [Eicosapentaenoic Acid results in increased expression of GSTM3 mRNA]increases expression|increases reaction 18489776
D004642 Emodin Emodin results in decreased expression of GSTM3 mRNAdecreases expression 16045814
D004918 Erythromycin Estolate Erythromycin Estolate results in decreased expression of GSTM3 mRNAdecreases expression 17522070
C010452 estradiol-17 beta-benzoate estradiol-17 beta-benzoate results in decreased expression of GSTM3 mRNAdecreases expression 15972882
D004958 Estradiol Estradiol results in increased expression of GSTM3 mRNAincreases expression 11331657
D004958 Estradiol Estradiol results in decreased expression of GSTM3 mRNAdecreases expression 14664709
D004958 Estradiol Estradiol results in decreased expression of GSTM3 mRNAdecreases expression 17522070
C015854 estradiol valerate estradiol valerate results in decreased expression of GSTM3 mRNAdecreases expression 15972882
D000431 Ethanol Ethanol results in increased expression of GSTM3 mRNAincreases expression 16098508
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of GSTM3 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of GSTM3 mRNAdecreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of GSTM3 mRNAaffects cotreatment|decreases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of GSTM3 mRNAdecreases expression 15834898
15576828
17557909
D011345 Fenofibrate [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNAaffects cotreatment|decreases expression 18253720
18775883
D011345 Fenofibrate Fenofibrate results in decreased expression of GSTM3 mRNAdecreases expression 18775883
D005419 Flavonoids Flavonoids results in decreased expression of GSTM3 mRNAdecreases expression 18035473
C056933 fumonisin B1 fumonisin B1 results in increased expression of GSTM3 mRNAincreases expression 16221962
D005978 Glutathione GSTM3 protein affects the metabolism of Glutathioneaffects metabolic processing 9545290
D007501 Iron [Copper co-treated with Diethylnitrosamine co-treated with Iron] results in increased expression of GSTM3 mRNAaffects cotreatment|increases expression 20302851
D007657 Ketone Bodies Ketone Bodies results in increased expression of GSTM3 mRNAincreases expression 16807920
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM3 mRNAaffects cotreatment|increases expression 17917374
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNAaffects cotreatment|decreases expression 18544905
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM3 mRNAaffects cotreatment|increases expression 18544905
D009270 Naloxone Naloxone results in decreased expression of GSTM3 mRNAdecreases expression 17522070
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in decreased expression of GSTM3 mRNAdecreases expression 17522070
D009532 Nickel Nickel affects the expression of GSTM3 mRNAaffects expression 19440498
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in decreased expression of GSTM3 mRNAdecreases expression 17616710
C042763 olive oil olive oil analog affects the expression of GSTM3 mRNAaffects expression 17349074
D010126 Ozone Ozone results in decreased expression of GSTM3 mRNAdecreases expression 12763052
D010269 Paraquat Paraquat results in increased expression of GSTM3 mRNAincreases expression 16128001
C023036 perfluorooctanoic acid perfluorooctanoic acid affects the expression of GSTM3 mRNAaffects expression 18281256
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of GSTM3 mRNAincreases expression 18281256
C023036 perfluorooctanoic acid PPARA protein inhibits the reaction [perfluorooctanoic acid results in increased expression of GSTM3 mRNA]decreases reaction|increases expression 18281256
D044262 Prostaglandin H2 GSTM3 protein affects the metabolism of Prostaglandin H2affects metabolic processing 10905636
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of GSTM3 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of GSTM3 mRNAincreases expression 19482888
19270015
D010656 Phenylephrine Phenylephrine results in decreased expression of GSTM3 mRNAdecreases expression 18158353
D010882 Piperonyl Butoxide Piperonyl Butoxide results in increased expression of GSTM3 mRNAincreases expression 18544911
C006253 pirinixic acid pirinixic acid results in decreased expression of GSTM3 mRNAdecreases expression 17426115
16221962
D011084 Polycyclic Hydrocarbons, Aromatic GSTM3 protein polymorphism results in increased susceptibility to Polycyclic Hydrocarbons, Aromaticincreases response to substance 11740339
11289100
C025299 polyphenols polyphenols results in decreased expression of GSTM3 mRNAdecreases expression 16293270
C045950 propiconazole propiconazole results in increased expression of GSTM3 mRNAincreases expression 16643972
D015232 Dinoprostone GSTM3 protein affects the chemical synthesis of Dinoprostoneaffects chemical synthesis 10905636
D011458 Prostaglandins E GSTM3 protein affects the chemical synthesis of Prostaglandins Eaffects chemical synthesis 10905636
D011794 Quercetin Quercetin results in decreased expression of GSTM3 mRNAdecreases expression 16455785
D011802 Quinidine Quinidine results in decreased expression of GSTM3 mRNAdecreases expression 17522070
C017947 sodium arsenite sodium arsenite affects the expression of GSTM3 mRNAaffects expression 16507464
C016766 sulforafan [sulforafan co-treated with dibenzoylmethane] results in increased expression of GSTM3 mRNAaffects cotreatment|increases expression 17942926
C016766 sulforafan sulforafan results in increased expression of GSTM3 mRNAincreases expression 17942926
C446685 systhane systhane results in increased expression of GSTM3 mRNAincreases expression 16643972
D013629 Tamoxifen Tamoxifen affects the expression of GSTM3 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of GSTM3 mRNAdecreases expression 16039398
D013749 Tetrachlorodibenzodioxin NFE2L2 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTM3 mRNA]affects reaction|increases expression 19474220
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of GSTM3 mRNAaffects binding|increases expression 16214954
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of GSTM3 mRNAaffects cotreatment|decreases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of GSTM3 mRNAdecreases expression 19465110
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of GSTM3 mRNAincreases expression 18172886
19474220
18796159
D013752 Tetracycline Tetracycline results in decreased activity of GSTM3 proteindecreases activity 11807801
D013752 Tetracycline Tetracycline results in decreased expression of GSTM3 mRNAdecreases expression 17522070
D013806 Theophylline Theophylline results in decreased expression of GSTM3 mRNAdecreases expression 17522070
D014050 Toluene Toluene affects the expression of GSTM3 mRNAaffects expression 18653662
C032910 triadimefon triadimefon results in increased expression of GSTM3 mRNAincreases expression 16643972
C010360 triethyllead triethyllead results in decreased expression of GSTM3 mRNAdecreases expression 9020200
D014315 Triterpenes Triterpenes results in increased expression of GSTM3 mRNAincreases expression 18544911
D014415 Tunicamycin Tunicamycin results in decreased expression of GSTM3 mRNAdecreases expression 17127020
D015029 Zeranol Zeranol results in increased expression of GSTM3 mRNAincreases expression 11331657
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.7614745880
MESH:D000014 Abnormalities, Drug-Induced Ethanol 9.8217676605 18926900
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 9.826195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 9.8215322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 7.9018287403
MESH:D000138 Acidosis Ethanol 7.9011192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.1517505938
MESH:D058186 Acute Kidney Injury Cisplatin 3.2715814532 17670903 12690470
MESH:D055371 Acute Lung Injury Nickel 6.8616166738
MESH:D055371 Acute Lung Injury pirinixic acid 6.8618653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 7.8420127859 20464547
MESH:D000230 Adenocarcinoma Cisplatin 7.8411798837 17638652
MESH:D000230 Adenocarcinoma Estradiol 7.8411473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 7.8414692618
MESH:D000236 Adenoma Benzo(a)pyrene 4.946695378
MESH:D000236 Adenoma Diethylnitrosamine 4.9410737359 6695378
MESH:D018248 Adenoma, Liver Cell dicyclanil 24.5417162532
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 24.5417620307 16434500 19052882 17162532 19061943 18056438
MESH:D018248 Adenoma, Liver Cell Phenobarbital 24.5417620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 24.5416434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 24.5416835633
MESH:D011125 Adenomatous Polyposis Coli dibenzoylmethane 12.7217942926
MESH:D011125 Adenomatous Polyposis Coli Dinoprostone 12.7217942926
MESH:D011125 Adenomatous Polyposis Coli sulforafan 12.7217942926
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.9115276417
MESH:D018246 Adrenocortical Adenoma Arsenic 11.1717306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 11.1717306315 16712894
MESH:D000382 Agricultural Workers' Diseases Chlorpyrifos 10.1317119214 16611668 11874814
MESH:D000382 Agricultural Workers' Diseases Diazinon 10.1316487989
MESH:D000382 Agricultural Workers' Diseases Paraquat 10.1311874814
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.5315451040 15451039
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 4.8716640825
MESH:D000544 Alzheimer Disease Copper 5.3616962711 17119284 16886094 16325427 16866297 16410023
MESH:D000544 Alzheimer Disease Iron 5.3616563566 16640825
MESH:D000544 Alzheimer Disease Ozone 5.3615513908
MESH:D000686 Amyloidosis Diethylstilbestrol 3.7415469931
MESH:D000690 Amyotrophic Lateral Sclerosis 4-hydroxy-2-nonenal 6.7410965797
MESH:D000690 Amyotrophic Lateral Sclerosis Copper 6.7410694572
MESH:D000740 Anemia Iron 6.6516434484 16566752
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.6511748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.5417084956
MESH:D018798 Anemia, Iron-Deficiency Copper 8.1916614410
MESH:D018798 Anemia, Iron-Deficiency Iron 8.1917163184 16569441 17147795 17162259 17375513
MESH:D000756 Anemia, Sideroblastic Iron 4.1116910769
MESH:D000799 Angioedema Acetaminophen 3.0510982225
MESH:D000853 Anophthalmos Ethanol 4.0615513904
MESH:D001008 Anxiety Disorders Ethanol 3.3711141031
MESH:D001014 Aortic Aneurysm Dinoprostone 4.8610231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 9.4719183758
MESH:D017544 Aortic Aneurysm, Abdominal Dinoprostone 9.4710388637
MESH:D001145 Arrhythmias, Cardiac Iron 11.2916604332
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 11.2917460149
MESH:D001145 Arrhythmias, Cardiac Quinidine 11.2918724381 18057881
MESH:D020261 Arsenic Poisoning Arsenic 2.5916251483 12569548 18414634 16835338
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 2.7111256880
MESH:D001169 Arthritis, Experimental Dexamethasone 5.6017659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 5.6015885639
MESH:D001172 Arthritis, Rheumatoid Ozone 2.3315570426
MESH:D001249 Asthma Ozone 4.4617854713 16373670
MESH:D001249 Asthma Theophylline 4.469701106 12113382
MESH:D001260 Ataxia Telangiectasia Iron 10.5315336622
MESH:D001260 Ataxia Telangiectasia Quercetin 10.5315336622
MESH:D050197 Atherosclerosis Arsenic 11.5619371607 12928151
MESH:D050197 Atherosclerosis Asbestos 11.5618795166
MESH:D050197 Atherosclerosis Iron 11.5616640825 16632123
MESH:D050197 Atherosclerosis olive oil 11.5616216721
MESH:D001321 Autistic Disorder Acetaminophen 2.3818445737
MESH:D001321 Autistic Disorder Docosahexaenoic Acids 2.3818582451
MESH:D001321 Autistic Disorder Glutathione 2.3819267885 16917939 19056591 18929414
MESH:D001321 Autistic Disorder Iron 2.3817352947
MESH:D001327 Autoimmune Diseases Quercetin 8.7519761891
MESH:D001327 Autoimmune Diseases sulforafan 8.7519761891
MESH:D001424 Bacterial Infections Iron 4.4216640825
MESH:D001477 Bartter Syndrome Dinoprostone 4.9815976003
MESH:D001778 Blood Coagulation Disorders pirinixic acid 6.4419483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 6.4412125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.0015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.2215746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.1014601052
MESH:D001919 Bradycardia Phenylephrine 3.7715306635
MESH:D001932 Brain Neoplasms Carmustine 7.1416187019
MESH:D001932 Brain Neoplasms Copper 7.1417079463
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 7.8220146248 17474063
MESH:D001943 Breast Neoplasms Cisplatin 7.8219526202 18382427
MESH:D001943 Breast Neoplasms Copper 7.8215986119 17079463
MESH:D001943 Breast Neoplasms decitabine 7.8218320071 19208741
MESH:D001943 Breast Neoplasms Dieldrin 7.8215770527 11859874
MESH:D001943 Breast Neoplasms Diethylnitrosamine 7.8217474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 7.8217129689 15324884
MESH:D001943 Breast Neoplasms Estradiol 7.8212948864 17261762 17289903 18497071 16675129 19861407 14630087 17018787
MESH:D001943 Breast Neoplasms Nickel 7.8215986119
MESH:D001943 Breast Neoplasms Quercetin 7.8218628248
MESH:D001943 Breast Neoplasms Tamoxifen 7.8218815881 17242785 11161223 18425577 19189210 17440819 20135344 19103187 19155303 19410462 19221464 19487384 15668708 18997820 19011961 20859285 15565566 20065188 19115204 18984771 18351453 16818667 20544844 20390343 19189212 19200415 17893378 19059307 19289846 19066611 18629630 16273361 16202921 20005174 19142967 16873071 18855134 19084267 17049068 19288272 17261762 21152245 21138602 18821012 19244106
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 7.8220435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.0518315731 17626835 18417511 16777450 15516495 14754758 19059883
MESH:D002056 Burns Ethanol 3.8916374292
MESH:D002100 Cachexia Ozone 3.9616183385
MESH:D002105 Cadmium Poisoning Quercetin 4.7516962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.6916111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.0318705752 15700767 16124888 15673190 15721981 16227642 10355542 16011737 3786805 16097048 16050911 16192424
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.1716835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.0915504454 17687452
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.7419066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 33.1016705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 33.1016705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 33.103084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 33.1017306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 33.1018788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 33.1017982673
MESH:D006528 Carcinoma, Hepatocellular dicyclanil 33.1017162532
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 33.1016807293 19052882 19394651 16328049 17428255 17761372 18210153 19919837 11831363 18978308 20084675 20214788 18785209 19208518 20935162 17138121 19519916 16502159 3581430 18788625 19335982 3084413 16681979 20727157 18691550 16569478 18056438 17173139 20101231 17978847 18494052 19171122 16540662 17055752 20432363 18393292 19383236 10672840 19107877 16288022 17162532 20514400 20524982 16878318 20007298 18506893 19822196 19539802 20512989 16935385 16779866 19701751 16830150 19418558 10737359 21159647 18665156 16698587 18971187
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 33.1016924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 33.1016924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 33.1015289165 15763234 18788625
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 33.1020007298 17173139 1701930 6705139 20935162
MESH:D006528 Carcinoma, Hepatocellular Quercetin 33.1019519916 12508355
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 33.1016507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 33.1016924424
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.7116685392 12023789
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.1917234771
MESH:D002294 Carcinoma, Squamous Cell Arsenic 14.0118922899 17687452 15504454
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 14.0120419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 14.0117066447 18337622 6189445
MESH:D002294 Carcinoma, Squamous Cell decitabine 14.0119215824
MESH:D002294 Carcinoma, Squamous Cell Glutathione 14.0117015178
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 14.0118572023
MESH:D002295 Carcinoma, Transitional Cell Arsenic 7.2218640142
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 7.2217572228
MESH:D006332 Cardiomegaly Copper 16.2517327471
MESH:D006332 Cardiomegaly Ethanol 16.2519332462
MESH:D006332 Cardiomegaly Phenylephrine 16.2517124262 11179087 15728586 16170337 11754973 17287366
MESH:D006332 Cardiomegaly Quercetin 16.2519794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 16.2518670907 16120746 18850075
MESH:D009202 Cardiomyopathies Iron 3.4916640825
MESH:D002311 Cardiomyopathy, Dilated Iron 3.1316604332
MESH:D002318 Cardiovascular Diseases Arsenic 6.0517938729 15738583 19152805
MESH:D002318 Cardiovascular Diseases olive oil 6.0516216721
MESH:D002340 Carotid Artery Diseases Arsenic 3.6416973168 18022660
MESH:D002386 Cataract Acetaminophen 2.0710977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 15.056135515
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 15.0521159647 17174075 7505956 2727394
MESH:D002471 Cell Transformation, Neoplastic Dinoprostone 15.0516192471
MESH:D002471 Cell Transformation, Neoplastic Estradiol 15.0518566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 15.0519524636 20056578
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.494080065
MESH:D002547 Cerebral Palsy Toluene 5.079294310
MESH:D002637 Chest Pain Theophylline 5.0815238202
MESH:D054506 Chloracne marker/mechanism 17101203
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.1019052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.1016835633
MESH:D002761 Cholangitis 1-Naphthylisothiocyanate 5.4112912871
MESH:D002779 Cholestasis 1-Naphthylisothiocyanate 10.0218590720 18164287 12927374 19486331 7624871 15913567 16629650 15500046
MESH:D002779 Cholestasis Ethinyl Estradiol 10.0211677210 16105132 15861022 17681005 17333356 17110522 16919318
MESH:D002779 Cholestasis pirinixic acid 10.0219176532
MESH:D002780 Cholestasis, Intrahepatic 1-Naphthylisothiocyanate 5.0610220858 19407337
MESH:D002971 Cleft Lip Ethanol 3.1215513904
MESH:D002972 Cleft Palate Ethanol 7.6315513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 7.6312621046 8697196 15668235 15340226 16354765
MESH:D002972 Cleft Palate triadimefon 7.6316781842
MESH:D003093 Colitis, Ulcerative Dinitrochlorobenzene 3.5317373747 19159591
MESH:D003110 Colonic Neoplasms decitabine 8.7017616700
MESH:D003110 Colonic Neoplasms Dexamethasone 8.7015824018
MESH:D003110 Colonic Neoplasms Iron 8.7016640825
MESH:D003110 Colonic Neoplasms polyphenols 8.7016293270
MESH:D003110 Colonic Neoplasms Quercetin 8.7011134977 17148506 19440933 15741050 19056647 16640504 17191121
MESH:D015179 Colorectal Neoplasms marker/mechanism 17892325
MESH:D015179 Colorectal Neoplasms Cisplatin 2.9515273666
MESH:D015179 Colorectal Neoplasms decitabine 2.9518981723
MESH:D015179 Colorectal Neoplasms Quercetin 2.9518095365 18852136
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.3914669216 17141729
MESH:D019465 Craniofacial Abnormalities Dexamethasone 5.8817728286
MESH:D019465 Craniofacial Abnormalities Ethanol 5.8811198716 19302082 11873399 15513904 10194807 15451039 15451040
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 5.8815322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Toluene 5.889294310
MESH:D019465 Craniofacial Abnormalities triadimefon 5.8815834900 16875885
MESH:D003456 Cryptorchidism Diethylstilbestrol 3.8112952375 16002989
MESH:D003490 Cyanosis 2,4-dinitrotoluene 8.3818551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 8.3818551238
MESH:D003550 Cystic Fibrosis Docosahexaenoic Acids 7.0619747007
MESH:D003550 Cystic Fibrosis Glutathione 7.0619747007
MESH:D003643 Death Toluene 4.886431079
MESH:D003711 Demyelinating Diseases Tamoxifen 3.6019031437
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 7.6412438553
MESH:D017449 Dermatitis, Allergic Contact Dinitrochlorobenzene 7.6415491423
MESH:D017449 Dermatitis, Allergic Contact Nickel 7.6417244072 19470301 17100760
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.0018249437
MESH:D003877 Dermatitis, Contact Nickel 3.922952479
MESH:D003920 Diabetes Mellitus Iron 3.7916604332 16640825
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.0919496084
MESH:D003922 Diabetes Mellitus, Type 1 Iron 3.0616506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 5.5820387270
MESH:D003924 Diabetes Mellitus, Type 2 Iron 5.5816506275
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 5.5817107852
MESH:D003928 Diabetic Nephropathies Estradiol 6.6219279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 6.6219279558
MESH:D003967 Diarrhea Dexamethasone 6.147237001
MESH:D003967 Diarrhea Dinoprostone 6.1411488427 10446763 7237001
MESH:D056486 Drug-Induced Liver Injury 1-Naphthylisothiocyanate 35.9317522070 18289764 20133375 7624871
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 35.9321346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 35.9321346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 35.9310663392 17906064 12540782 19085960 11743745 16177239 12594235 12705907 19923254 16081117 11529661 17522070 17562736 10915739 16485898 11421492 19420014 14725611 19739265 16781746 12392966 11834606 12153990 16227642 19164858 18071297 11739529 11461765 18713872 14986274 15619225 19416960 14550746 16109766 2444490 12958197 11287661 15968718 16393943 10774834 19370779
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 35.9321278145 7120509 2869522 19336974 4309450 16227642 16177239 3786805 19085960 10092053 15968718 15998439 10915739 3732212 17522070 15027814 9327722 11566570 7440962 6884620 6623471 7179309
MESH:D056486 Drug-Induced Liver Injury Chloroform 35.936884620 17522070 3732212 7440962 3104120 7120509 2862719 6623471
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 35.9317654400
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 35.9319107877
MESH:D056486 Drug-Induced Liver Injury Erythromycin Estolate 35.9317522070 14998559
MESH:D056486 Drug-Induced Liver Injury Ethanol 35.9311566570
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 35.9316221962
MESH:D056486 Drug-Induced Liver Injury polyphenols 35.9319370779
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 35.9320420201
MESH:D056486 Drug-Induced Liver Injury Tetracycline 35.9317522070
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.3119426721
MESH:D004362 Drug Toxicity Cisplatin 6.1615033597 12649298 12231392 19839026
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.1611462148
MESH:D050171 Dyslipidemias Fenofibrate 3.8316707586
MESH:D004417 Dyspnea Diazinon 4.0216487989
MESH:D004421 Dystonia Phenobarbital 3.281851702
MESH:D004485 Eczema Dexamethasone 3.7212438553
MESH:D004487 Edema Dexamethasone 10.8119703484
MESH:D004487 Edema perfluorooctanoic acid 10.8112083418 17259670
MESH:D004487 Edema pirinixic acid 10.8112083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.8111000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.1116714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 6.5012538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 6.5019031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.3219294695
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 3.9216402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 13.2815700306 16804899
MESH:D016889 Endometrial Neoplasms Estradiol 13.2811473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Fenofibrate 13.2816569247
MESH:D016889 Endometrial Neoplasms Tamoxifen 13.2817893378 20544844 16202921 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.3410568697 9294722
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.353659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.093922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.4420417680
MESH:D004832 Epilepsy, Absence Naloxone 7.256254150
MESH:D004832 Epilepsy, Absence Phenobarbital 7.256401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.497750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.253659116
MESH:D007172 Erectile Dysfunction estradiol valerate 5.0814972507
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.3216302075
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 8.1016530937
MESH:D004938 Esophageal Neoplasms Cisplatin 8.1016481741 15464296 17638652 15173087 16785472
MESH:D004938 Esophageal Neoplasms Ethanol 8.1016704527
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 8.1015547733 16704527 16510608 15547721 15264214 15623463 15878914 16805852 15150132
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.4011564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 31.1212631006 61145 12795759 19224547 15959796 16045604 17595544 16239168
MESH:D005234 Fatty Liver Diethylnitrosamine 31.1221071580 20387270
MESH:D005234 Fatty Liver Ethanol 31.1218620774 16409862 19236843
MESH:D005234 Fatty Liver Ethinyl Estradiol 31.1215345470
MESH:D005234 Fatty Liver Iron 31.1216640825
MESH:D005234 Fatty Liver pirinixic acid 31.1220131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 31.1214986274 19224547
MESH:D005234 Fatty Liver Tetracycline 31.1219224547 16917069
MESH:D005235 Fatty Liver, Alcoholic Ethanol 4.8717920746
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 6.4516534752 16611131 15751030 16513791 16002989
MESH:D052776 Female Urogenital Diseases Tamoxifen 6.4516709447
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.5216946407 15451040 10194807 15513904
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.7011858732
MESH:D005334 Fever Dinoprostone 4.2016997862 11852909
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.7514745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.4119069698
MESH:D005355 Fibrosis Carbon Tetrachloride 15.0818705752
MESH:D005355 Fibrosis Emodin 15.0819474275
MESH:D005355 Fibrosis Quercetin 15.0819474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 15.0820067830
MESH:D005534 Foot Diseases Arsenic 4.776392382
MESH:D005621 Friedreich Ataxia Iron 4.6716604332 16640825
MESH:D005756 Gastritis Acetaminophen 8.5116983495
MESH:D005756 Gastritis Ethanol 8.5115046732
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 10.2416452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 10.2416452187
MESH:D005909 Glioblastoma Carmustine 5.7616187019
MESH:D005909 Glioblastoma Quercetin 5.7619804834
MESH:D005910 Glioma Quercetin 2.6817643826
MESH:D005911 Gliosis Paraquat 4.3711124998
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.8010696789
MESH:D006258 Head and Neck Neoplasms Cisplatin 6.1415464296 15102660
MESH:D006258 Head and Neck Neoplasms decitabine 6.1419215824
MESH:D034381 Hearing Loss Cisplatin 3.6319898482
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.7615464296
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 4.8620471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 4.8610048152 11294989
MESH:D006333 Heart Failure pirinixic acid 2.0220558911
MESH:D006432 Hemochromatosis Iron 3.8916574947 17053826 16640825 17236123 17255318 16604332
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.6311000095
MESH:D006486 Hemosiderosis Iron 4.4216604332
MESH:D006505 Hepatitis 1-Naphthylisothiocyanate 11.6718590720
MESH:D006505 Hepatitis Carbon Tetrachloride 11.6719900420 19110552
MESH:D006505 Hepatitis Diazinon 11.6716487989
MESH:D006521 Hepatitis, Chronic Copper 4.4917338147
MESH:D006525 Hepatitis, Viral, Human Iron 4.6816640825
MESH:D006527 Hepatolenticular Degeneration Copper 8.9619888908 16607473 17109627 17276780 17182432
MESH:D006527 Hepatolenticular Degeneration Iron 8.9617182432
MESH:D006529 Hepatomegaly fumonisin B1 39.7916221962
MESH:D006529 Hepatomegaly Iron 39.7916890145
MESH:D006529 Hepatomegaly perfluorooctanoic acid 39.793609246
MESH:D006529 Hepatomegaly Phenobarbital 39.7916109766
MESH:D006529 Hepatomegaly pirinixic acid 39.7918467677 16221962 19176532 19772884
MESH:D006529 Hepatomegaly propiconazole 39.7917178689 17178688
MESH:D006529 Hepatomegaly systhane 39.7917178689 17178688
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 39.7915340226 16120746 12621046
MESH:D006529 Hepatomegaly triadimefon 39.7917178688 17178689
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.737520565
MESH:D006558 Herpes Genitalis Estradiol 4.2415709030
MESH:D015658 HIV Infections Iron 5.5716597321
MESH:D015658 HIV Infections Nickel 5.5717263646
MESH:D006689 Hodgkin Disease Cisplatin 5.3716200630 16170182
MESH:D006689 Hodgkin Disease sodium arsenite 5.3712676792
MESH:D019584 Hot Flashes Estradiol 2.9717088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.258697196 16354765 15340226 18606429 16959395
MESH:D006930 Hyperalgesia Acetaminophen 13.5616870215
MESH:D006930 Hyperalgesia Dinoprostone 13.5616793879
MESH:D006930 Hyperalgesia Ethanol 13.5618783367
MESH:D006930 Hyperalgesia perfluorooctanoic acid 13.5612083418
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.7516899240
MESH:D006943 Hyperglycemia pirinixic acid 6.9620558911
MESH:D006943 Hyperglycemia Quercetin 6.9611834736 18262572
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 3.7717050553
MESH:D006965 Hyperplasia Diethylstilbestrol 3.6812960047 14722030
MESH:D006973 Hypertension Arsenic 12.3916076760 9931084 11953799
MESH:D006973 Hypertension Dexamethasone 12.3917042910
MESH:D006973 Hypertension Phenylephrine 12.398949925 12717712
MESH:D006973 Hypertension Quercetin 12.3918356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 12.3918850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.3315338365
MESH:D006984 Hypertrophy Phenylephrine 3.8518502941 12791704
MESH:D006987 Hypesthesia Arsenic 4.7716093927
MESH:D007006 Hypogonadism Iron 3.8216640825
MESH:D007021 Hypospadias Diethylstilbestrol 8.7216002989
MESH:D007021 Hypospadias Ethinyl Estradiol 8.7216945680 16569931
MESH:D007037 Hypothyroidism Iron 4.3216640825
MESH:D007246 Infertility Diethylstilbestrol 3.6215036965
MESH:D007247 Infertility, Female Dieldrin 7.8910630421
MESH:D007247 Infertility, Female Ethinyl Estradiol 7.8912013081
MESH:D007248 Infertility, Male decitabine 19.1317581917
MESH:D007248 Infertility, Male Diazinon 19.1312948887 16466525
MESH:D007248 Infertility, Male Ethinyl Estradiol 19.1317937319
MESH:D007248 Infertility, Male Paraquat 19.134850670
MESH:D007248 Infertility, Male sodium arsenite 19.1312646999 15346721
MESH:D007248 Infertility, Male Theophylline 19.1316988215
MESH:D007249 Inflammation Dexamethasone 20.3511099482 8960868
MESH:D007249 Inflammation Diethylnitrosamine 20.3518785209
MESH:D007249 Inflammation Flavonoids 20.3517296493
MESH:D007249 Inflammation Nickel 20.3516166738
MESH:D007249 Inflammation perfluorooctanoic acid 20.3512083418
MESH:D007249 Inflammation polyphenols 20.3516366677
MESH:D007249 Inflammation Tamoxifen 20.3519457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 20.3512878042 12200463
MESH:D007251 Influenza, Human Quercetin 3.7216624496
MESH:D007333 Insulin Resistance Estradiol 5.3516393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 5.3516306350
MESH:D019189 Iron Metabolism Disorders Iron 4.3117163184
MESH:D007569 Jaw Abnormalities Ethanol 13.2615513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 13.2616580747
MESH:D007569 Jaw Abnormalities triadimefon 13.2615992940 15834900
MESH:D007627 Keloid Quercetin 4.1917086741
MESH:D007642 Keratosis Arsenic 4.2116930632 12749816
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.3515464296
MESH:D007674 Kidney Diseases Acetaminophen 13.7012587719 15629191
MESH:D007674 Kidney Diseases Cisplatin 13.7012649298 19839026 12231392 18289764 15190930
MESH:D007674 Kidney Diseases Estradiol 13.7015618244
MESH:D007674 Kidney Diseases Quercetin 13.7016962696
MESH:D007674 Kidney Diseases sodium arsenite 13.7020008137
MESH:D007676 Kidney Failure, Chronic Copper 4.2016518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 16.5116705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 16.5116705839
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 16.5116762066 15003126 14681315
MESH:D007680 Kidney Neoplasms Estradiol 16.5115610895
MESH:D007680 Kidney Neoplasms Tamoxifen 16.5118625569
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.0111231351
MESH:D007859 Learning Disorders Copper 11.8817134702
MESH:D007859 Learning Disorders Diethylstilbestrol 11.8817184923
MESH:D007859 Learning Disorders Ethanol 11.8815451040
MESH:D007938 Leukemia decitabine 5.0519235587 18980019
MESH:D007938 Leukemia Quercetin 5.0517468513
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Docosahexaenoic Acids 8.1717077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Emodin 8.1717077332
MESH:D007951 Leukemia, Myeloid decitabine 3.3019117987 18454857 17236224
MESH:D015470 Leukemia, Myeloid, Acute decitabine 2.2119387464 18460780 18206229 19010910 18704418 17679729
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.6718055864
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.0017339181
MESH:D020961 Lewy Body Disease Iron 4.6716563566
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 4.458812269
MESH:D017880 Limb Deformities, Congenital Ethanol 3.2217676605
MESH:D008064 Lipidoses Tamoxifen 2.5717567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 15.5411408273 17174718 16943688 17334410 17157831 21278145 16239168 11903743 16221502
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 15.5418665156 20032147 18522880 19638242 18407596
MESH:D008103 Liver Cirrhosis Ethanol 15.5415289165
MESH:D008103 Liver Cirrhosis Iron 15.5416640825
MESH:D008103 Liver Cirrhosis Phenobarbital 15.5421047994
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.3218295389
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 16.9717565644 12958196 15893842 16027843 16011737 18187930 15650968 18279442 18317297 10355542 17976157 17721639 16116963 17944888 15959796 15996030 18263696 15052691 18277467 15057751 17922224 18705752 15818738 12586293 12666154 12741479 18251166 18420326 18472332 13678700 12632514 12609069 17698563 18395095 16136751 16097048 17708605 17900296 15338365 16033810 12546737 18205269 16015684 15876570 18395914 14716833 17823541 11481614 18054572 15362042 14620537 17640975 18006644 12445421 18472094 18339082 14748882 18481824 12898905 17525996 16248980 17766677 14512876 15123356 15673190 18166357 17761835 12667390 15925388 14724832 16192424 18418968 12632512 18429990 15931870 20821823 16638106 18156304 17631135 17805973 15730626 12389079 15370692 17557913 17869086 17481882 18210741 12649538 17714472 18376398 18412020 12445418 14716496
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 16.9716718785
MESH:D008106 Liver Cirrhosis, Experimental Dinoprostone 16.9715816358
MESH:D008106 Liver Cirrhosis, Experimental Emodin 16.9715288473
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 16.9714659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 16.9718166357
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 16.9715474484
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 16.9715474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 16.9712741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 16.9718564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 16.9712878042
MESH:D008107 Liver Diseases 1-Naphthylisothiocyanate 31.1717184895
MESH:D008107 Liver Diseases Acetaminophen 31.1716610002 19784758 11587558 19460945 16611625 12969438 12587719 19014921
MESH:D008107 Liver Diseases Arsenic 31.1711134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 31.1715830285 17285989 16964402 15720792 16246199
MESH:D008107 Liver Diseases Chlorpyrifos 31.1715991261
MESH:D008107 Liver Diseases Diethylnitrosamine 31.1717034775
MESH:D008107 Liver Diseases Dinoprostone 31.1715816358
MESH:D008107 Liver Diseases Docosahexaenoic Acids 31.1717056761
MESH:D008107 Liver Diseases Phenobarbital 31.1719363144
MESH:D008107 Liver Diseases polyphenols 31.1716698588
MESH:D008107 Liver Diseases propiconazole 31.1719363144
MESH:D008107 Liver Diseases triadimefon 31.1719363144
MESH:D008108 Liver Diseases, Alcoholic Ethanol 8.9717347304 17207112
MESH:D008108 Liver Diseases, Alcoholic Iron 8.9717207112 16737972
MESH:D017093 Liver Failure Carbon Tetrachloride 3.4115123358
MESH:D017114 Liver Failure, Acute Acetaminophen 7.1317185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 7.1314706259 16899240
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 74.507678174
MESH:D008113 Liver Neoplasms Arsenic 74.5016368122
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 74.5021137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 74.5019294768
MESH:D008113 Liver Neoplasms Clofibric Acid 74.5017602206
MESH:D008113 Liver Neoplasms Copper 74.5020302851
MESH:D008113 Liver Neoplasms dicyclanil 74.5020118626
MESH:D008113 Liver Neoplasms Dieldrin 74.509539021 8742319
MESH:D008113 Liver Neoplasms Diethylnitrosamine 74.5019254457 19642983 19690152 15885732 12112319 19427195 21278145 21167192 18644402 20118626 18648771 18978307 20101389 19996281 12771043 19833225 20137499 20583210 19499222 20501860 20452335 16942905 19426721 19551842 2862719 19073162 19294768 21071580 19638242 21047994 18754104 19255062 19812893 19850985 15175105 20434301 18977376 19090486 20492335 2422723 20405173 9163691 10737359 19256749
MESH:D008113 Liver Neoplasms Diethylstilbestrol 74.5015890375 16712894
MESH:D008113 Liver Neoplasms Fenofibrate 74.5018978307
MESH:D008113 Liver Neoplasms Iron 74.5020302851 16640825
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 74.5014757943 18709148
MESH:D008113 Liver Neoplasms Phenobarbital 74.5019482888 19812893 21047994 15975961 8742319 19073162
MESH:D008113 Liver Neoplasms Piperonyl Butoxide 74.5020101389 15890375 19690152 18648771
MESH:D008113 Liver Neoplasms pirinixic acid 74.5016377806 20007298 15890375
MESH:D008113 Liver Neoplasms propiconazole 74.5019028983
MESH:D008113 Liver Neoplasms Quercetin 74.5018980244
MESH:D008113 Liver Neoplasms sodium arsenite 74.5015276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 74.5016684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 74.5016984957
MESH:D008113 Liver Neoplasms triadimefon 74.5019028983
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 36.092876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 36.0912014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 36.0918164116 16267830 19004024 9362446 18253720 18079962 17174075 19009564 21159647 19539802 19126423 18544905 16842330 18775883 19519916 17942915 18308698 2563599 3124819 17854601 18093689 18282651
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 36.0918775883 18253720
MESH:D008114 Liver Neoplasms, Experimental kojic acid 36.0918544905
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 36.091399818 6150874 17172636 18308698 2563599
MESH:D008114 Liver Neoplasms, Experimental propiconazole 36.0917178689
MESH:D008114 Liver Neoplasms, Experimental Quercetin 36.0919519916
MESH:D008114 Liver Neoplasms, Experimental systhane 36.0917178689
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 36.0912151625
MESH:D008114 Liver Neoplasms, Experimental triadimefon 36.0917178689
MESH:D008133 Long QT Syndrome Quinidine 4.3211989578 15350150
MESH:D008171 Lung Diseases Ozone 5.6419066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 5.6419095001
MESH:D055370 Lung Injury Ozone 3.1020417186
MESH:D008175 Lung Neoplasms Arsenic 21.4417306315 19168569 17976673
MESH:D008175 Lung Neoplasms Asbestos 21.4412111688
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 21.4420464547 17053015 18569708 20064080 18816296 6695378 20869020 20135361 18520028
MESH:D008175 Lung Neoplasms Cisplatin 21.446189445 11798837 17225452
MESH:D008175 Lung Neoplasms Dexamethasone 21.4415824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 21.4420970405 20512841 6695378 21163286
MESH:D008175 Lung Neoplasms Iron 21.4416640825
MESH:D008175 Lung Neoplasms Ozone 21.448597069 7614698
MESH:D008175 Lung Neoplasms Polycyclic Hydrocarbons, Aromatic 21.4410814675
MESH:D008175 Lung Neoplasms Quercetin 21.4416280456
MESH:D008175 Lung Neoplasms sodium arsenite 21.4417306315 15276417 16712894 17077188 19931552
MESH:D008175 Lung Neoplasms Tamoxifen 21.4418625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 21.4411884234 19555203
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.3715166399
MESH:D008223 Lymphoma decitabine 5.7719470736
MESH:D008223 Lymphoma Diethylstilbestrol 5.7715700306
MESH:D008268 Macular Degeneration Iron 3.4916640825
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.7216002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 2.9919428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 4.1917203775 11807958 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 4.1911731420 16827153 14580682 19196723 19196722
MESH:D020149 Manganese Poisoning Estradiol 10.0219453300
MESH:D020149 Manganese Poisoning Tamoxifen 10.0219453300
MESH:D008545 Melanoma Carmustine 9.7212393984
MESH:D008545 Melanoma Cisplatin 9.7217023156 12393984 15577323 12883367 17761969 11135225 18505091 18332650 16248763 12374674 16432458 16809738 18176117
MESH:D008545 Melanoma decitabine 9.7217785578 16505122
MESH:D008545 Melanoma Dinitrochlorobenzene 9.7212202904 17334785
MESH:D008545 Melanoma sodium arsenite 9.7219082730 16487513
MESH:D008545 Melanoma Tamoxifen 9.7212393984 19393235
MESH:D018328 Melanoma, Amelanotic Cisplatin 8.9415990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 8.9415990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.8119513568
MESH:D008569 Memory Disorders Ethanol 3.4618411066 15451040
MESH:D007706 Menkes Kinky Hair Syndrome Copper 5.1017268249 17109627
MESH:D008607 Mental Retardation Toluene 3.329294310
MESH:D008654 Mesothelioma Asbestos 5.5416564556 18709470 16319530 18310086 16919927
MESH:D008654 Mesothelioma Cisplatin 5.5417638057
MESH:D008679 Metaplasia Ozone 4.3110496685
MESH:D020326 Migraine without Aura Dinoprostone 4.5211304026
MESH:D019957 Motor Skills Disorders Toluene 4.519294310
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.5716381670
MESH:D009101 Multiple Myeloma decitabine 5.5718172295
MESH:D009101 Multiple Myeloma Dexamethasone 5.5715867202 16118317 15744524
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 4.8817086897
MESH:D009135 Muscular Diseases pirinixic acid 2.7516239165
MESH:D009181 Mycoses Iron 4.6816640825
MESH:D009190 Myelodysplastic Syndromes decitabine 5.9616882708 19010910 18608210 19157545
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 5.969809623
MESH:D009203 Myocardial Infarction pirinixic acid 4.4019151258
MESH:D009203 Myocardial Infarction Quercetin 4.4019595682
MESH:D017202 Myocardial Ischemia Arsenic 11.6715371236
MESH:D017202 Myocardial Ischemia Iron 11.6716604332
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 11.6712213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 15.2316810080
MESH:D015428 Myocardial Reperfusion Injury Iron 15.2316604332
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 15.2316411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 15.2319207477
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.7017484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 7.7818551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 7.787678174 18551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 4.449029167 3581430
MESH:D009362 Neoplasm Metastasis Tamoxifen 4.4419393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.2019410462
MESH:D009369 Neoplasms Benzo(a)pyrene 20.4011141357
MESH:D009369 Neoplasms Cisplatin 20.4016773208
MESH:D009369 Neoplasms decitabine 20.4019116145 17925555 19470736
MESH:D009369 Neoplasms Dieldrin 20.408820588
MESH:D009369 Neoplasms Diethylstilbestrol 20.4015313581
MESH:D009369 Neoplasms pirinixic acid 20.4017405874
MESH:D009369 Neoplasms Quercetin 20.4015185748
MESH:D009369 Neoplasms sodium arsenite 20.4011559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 2.9220056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.2119196722 19189210 19200415
MESH:D009389 Neovascularization, Pathologic Copper 7.7817308104
MESH:D009389 Neovascularization, Pathologic Estradiol 7.7817289903
MESH:D009395 Nephritis, Interstitial Cisplatin 8.2315464296
MESH:D009395 Nephritis, Interstitial Tetracycline 8.239884423
MESH:D009404 Nephrotic Syndrome Iron 3.8517178036
MESH:D009410 Nerve Degeneration Paraquat 3.1016893418
MESH:D009421 Nervous System Malformations Diethylstilbestrol 12.1211399458
MESH:D009421 Nervous System Malformations Estradiol 12.1216427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 12.1214600291
MESH:D009436 Neural Tube Defects Arsenic 5.6216620997
MESH:D009436 Neural Tube Defects sodium arsenite 5.6212854658
MESH:D009447 Neuroblastoma Cisplatin 2.998761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 10.3518514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 10.3520387270
MESH:D019636 Neurodegenerative Diseases Iron 10.3517296847 16604332
MESH:D017599 Neuroectodermal Tumors Cisplatin 3.928761367
MESH:D020078 Neurogenic Inflammation Arsenic 8.2917056641
MESH:D020078 Neurogenic Inflammation Quercetin 8.2917929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.3220387270
MESH:D020258 Neurotoxicity Syndromes Chlorpyrifos 3.6015081274
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.199802331
MESH:D009765 Obesity pirinixic acid 1.5720558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 6.6116049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 6.6116049721
MESH:D010003 Osteoarthritis Iron 3.4516640825
MESH:D010005 Osteoarthropathy, Secondary Hypertrophic Dinoprostone 5.6818500342
MESH:D010018 Osteomalacia Phenobarbital 3.5917016548
MESH:D010024 Osteoporosis Iron 3.3416640825 16648989
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 3.5019495926
MESH:D010051 Ovarian Neoplasms Arsenic 14.5817306315
MESH:D010051 Ovarian Neoplasms Cisplatin 14.5817225452 6897625 19769630 15464296
MESH:D010051 Ovarian Neoplasms decitabine 14.5819259094 19331143
MESH:D010051 Ovarian Neoplasms Estradiol 14.5819401270
MESH:D010051 Ovarian Neoplasms Quercetin 14.5819005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 14.5815276417 17306315
MESH:D010146 Pain Acetaminophen 1.7816870215
MESH:D010190 Pancreatic Neoplasms Cisplatin 15.7919003803
MESH:D010190 Pancreatic Neoplasms decitabine 15.7919294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 15.7916540662
MESH:D010190 Pancreatic Neoplasms Ethanol 15.7912384795
MESH:D010190 Pancreatic Neoplasms Phenobarbital 15.7916965848
MESH:D010190 Pancreatic Neoplasms Quercetin 15.7916965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.9611578682
MESH:D010212 Papilloma cumene hydroperoxide 7.6417234724 12065085
MESH:D010212 Papilloma Iron 7.6412065085
MESH:D020447 Parasomnias Iron 5.2317352947
MESH:D010300 Parkinson Disease Dieldrin 6.7516809432 11181820 16112328 17291500 11445065
MESH:D010300 Parkinson Disease Iron 6.7516640825 16563566
MESH:D010300 Parkinson Disease Paraquat 6.7516510128 15451049 15824117 11445065 11181820 12911755 11124998 16140633
MESH:D010302 Parkinson Disease, Secondary Paraquat 3.6716190885
MESH:D010382 Peliosis Hepatis 1-Naphthylisothiocyanate 11.1620133375
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 11.1612520081
MESH:D010391 Pemphigoid, Bullous Tetracycline 4.6411026799
MESH:D010523 Peripheral Nervous System Diseases Arsenic 7.6116093927
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 7.6115464296
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.216392382 16905509 15371236
MESH:D010538 Peritonitis Ozone 3.3816369182
MESH:D010787 Photosensitivity Disorders 4-hydroxy-2-nonenal 4.7111550810
MESH:D010900 Pituitary Diseases Diethylstilbestrol 11.4314722030
MESH:D010900 Pituitary Diseases Iron 11.4316604332
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 3.9116977796 15687265
MESH:D010997 Pleural Neoplasms Cisplatin 4.5517638057
MESH:D011014 Pneumonia Ozone 8.5018007984 18381685 18929643
MESH:D011014 Pneumonia Paraquat 8.5012504350
MESH:D011041 Poisoning Diazinon 6.8317603234
MESH:D011041 Poisoning Iron 6.8316604332
MESH:D017119 Porphyria Cutanea Tarda Iron 8.5616640825
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 8.5618163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 11.512563599
MESH:D011230 Precancerous Conditions Phenobarbital 11.512563599
MESH:D011230 Precancerous Conditions Quercetin 11.5119056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.0521297632
MESH:D011225 Pre-Eclampsia Iron 3.8016640825
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 11.8917184923
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 11.8917132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 11.8911896295 11399792 11222880 11118676
MESH:D055728 Primary Myelofibrosis decitabine 3.9717616702
MESH:D017096 Prion Diseases Tetracycline 4.6410903871
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.1820887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 14968442
MESH:D011471 Prostatic Neoplasms Arsenic 2.1516140617
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.1517292933
MESH:D011471 Prostatic Neoplasms Copper 2.1517308104 17079463
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.1515046698 15846301 17136230
MESH:D011471 Prostatic Neoplasms Estradiol 2.1516740699
MESH:D011471 Prostatic Neoplasms Quercetin 2.1517292933 14715546
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.1516039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.1515067354
MESH:D011507 Proteinuria Arsenic 3.2921343184
MESH:D011528 Protozoan Infections Iron 5.2316640825
MESH:D011537 Pruritus Ethinyl Estradiol 7.4715861022 16919318
MESH:D011537 Pruritus Naloxone 7.4715861022
MESH:D019310 Pseudolymphoma Phenobarbital 3.7012752131
MESH:D029424 Pulmonary Disease, Chronic Obstructive Theophylline 4.5218983928
MESH:D011658 Pulmonary Fibrosis Paraquat 2.5617997886 16324872
MESH:D051437 Renal Insufficiency Cisplatin 3.6515464296
MESH:D015427 Reperfusion Injury pirinixic acid 1.9519058328
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 6.8818379247 11700416
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 6.8811700416
MESH:D012135 Respiratory Sounds Chlorpyrifos 7.4416611668 11874814 17119214
MESH:D012135 Respiratory Sounds Paraquat 7.4411874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.0918990726
MESH:D012140 Respiratory Tract Diseases Chlorpyrifos 4.1116611668 17119214
MESH:D012148 Restless Legs Syndrome Iron 3.9316930377
MESH:D012162 Retinal Degeneration Paraquat 3.2616458197
MESH:D012208 Rhabdomyosarcoma decitabine 3.6819155313
MESH:D012512 Sarcoma, Ewing's Cisplatin 3.6914601052
MESH:D012554 Schistosomiasis japonica Quercetin 4.7516862918
MESH:D012559 Schizophrenia Copper 2.9616842975
MESH:D012640 Seizures 2,4-dinitrotoluene 12.6118551238
MESH:D012640 Seizures 2,6-dinitrotoluene 12.6118551238
MESH:D012640 Seizures Ethanol 12.619754883
MESH:D012640 Seizures Phenobarbital 12.614039156 11442880 16876388 3137016
MESH:D012640 Seizures Toluene 12.616431079 9294310
MESH:D003294 Seizures, Febrile Phenobarbital 4.046407741
MESH:D012729 Sex Chromosome Aberrations Chlorpyrifos 5.306418539
MESH:D012852 Sinusitis Phenylephrine 3.937327846
MESH:D012871 Skin Diseases Arsenic 2.4917938729 19834688 17453740 6392382 17050553 17548696 16702368 16353154 15952646 16759981 18709164
MESH:D012878 Skin Neoplasms Arsenic 16.7917029826 19538983 17976673 16251483 15504454 17050553
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 16.7919755658 10029692
MESH:D012878 Skin Neoplasms cumene hydroperoxide 16.7912065085 8532709 17234724
MESH:D012878 Skin Neoplasms Iron 16.7912065085
MESH:D012878 Skin Neoplasms sodium arsenite 16.7919524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 16.7916192470
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.5515464296
MESH:D013088 Spermatocele Diethylstilbestrol 15.5816709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 15.5816709447
MESH:D013088 Spermatocele Tamoxifen 15.5816709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.2719457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.1712854658
MESH:D013272 Stomach Diseases Dexamethasone 3.5515472012
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 10.242093021 20155912
MESH:D013274 Stomach Neoplasms Butylated Hydroxyanisole 10.243581430 1399818
MESH:D013274 Stomach Neoplasms Cisplatin 10.2417522103 15958060 18396642
MESH:D013274 Stomach Neoplasms decitabine 10.2419037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 10.2418456281
MESH:D013274 Stomach Neoplasms Docosahexaenoic Acids 10.2419015929
MESH:D013274 Stomach Neoplasms Ethanol 10.2418456281
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 10.2412958204 17575124
MESH:D013276 Stomach Ulcer Dexamethasone 8.3315138204
MESH:D013276 Stomach Ulcer Ethanol 8.339211565 17918041 17189318 11906479 9562338 16755016
MESH:D013276 Stomach Ulcer olive oil 8.3312498302 16252198
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.579754883
MESH:D013398 Sudden Infant Death Iron 4.6716640825
MESH:D013705 Temporomandibular Joint Disorders polyphenols 4.4617997062
MESH:D013733 Testicular Diseases Toluene 4.1910048760 10514026
MESH:D013736 Testicular Neoplasms Cisplatin 3.9117225452 15464296
MESH:D013921 Thrombocytopenia 1-Naphthylisothiocyanate 4.0720133375
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.9011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.4915669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.1112697716
MESH:D013964 Thyroid Neoplasms decitabine 12.1217967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 12.127505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 12.121399818
MESH:D013964 Thyroid Neoplasms triadimefon 12.1217178689
MESH:D013978 Tibial Fractures Estradiol 3.8919048282
MESH:D014376 Tuberculosis Iron 3.5516597321
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 33.0316049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 33.0316049721
MESH:D001749 Urinary Bladder Neoplasms Arsenic 33.0311144890 18640142 19322015 19429237 17976673 15987713 17306315
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 33.0317053015
MESH:D001749 Urinary Bladder Neoplasms Butylated Hydroxyanisole 33.031399818
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 33.0312973940 15464296 17225452
MESH:D001749 Urinary Bladder Neoplasms decitabine 33.0317616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 33.0317306315 16452187 16712894
MESH:D001749 Urinary Bladder Neoplasms Quercetin 33.0316720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 33.0311723127 17306315 16452187 16712894
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 33.038653321 16712894 17572228
MESH:D014570 Urologic Diseases Diazinon 4.4916487989
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 9.4110091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 9.4110091137
MESH:D014581 Urticaria Acetaminophen 2.2710982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 11.9916803524
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 11.9916175088
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 11.9911813266
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.3814652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 7.0315809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 7.0314692618
MESH:D014604 Uveal Neoplasms decitabine 4.1217785578
MESH:D014605 Uveitis Dexamethasone 4.031336536
MESH:D014625 Vaginal Neoplasms Cisplatin 8.5715577323
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 8.5716002989 16513791
MESH:D014652 Vascular Diseases Arsenic 9.2717056641
MESH:D014652 Vascular Diseases sodium arsenite 9.2717056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.8012125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.8314671159 15869587
MESH:D014839 Vomiting Cisplatin 3.9311897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.4615886252
Pathway ID Pathway Name
KEGG:00982 Drug metabolism - cytochrome P450
KEGG:00480 Glutathione metabolism
KEGG:00980 Metabolism of xenobiotics by cytochrome P450
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA29024
    • Releated gene ID Related gene Name
    PA27092CYP1A1
    PA29028GSTP1
    PA18NAT2
    Releated disease ID Related disease Name
    PA444818Lung Neoplasms
    PA443340Anemia
    PA445301Peripheral Nervous System Diseases
    PA445846Thrombocytopenia
    PA444447Carcinoma, Hepatocellular
    Releated drug ID Related drug Name
    PA449014cisplatin
    PA449165cyclophosphamide
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00143 - BSS Plus Dietary supplement;Micronutrient
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved