AutismKB 2.0

Annotation Detail for GSTT1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GSTT1 ( - )
Gene Full Name: glutathione S-transferase theta 1
Band: 22q11.23 alternate reference locus
Quick LinksEntrez ID:2952; OMIM: 600436; Uniprot ID:GSTT1_HUMAN; ENSEMBL ID: ENSG00000184674; HGNC ID: 4641
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-4061glutathione-mediated detoxification
Pathway IDPathway Name
hsa00480Glutathione metabolism
hsa00980Metabolism of xenobiotics by cytochrome P450
hsa00982Drug metabolism - cytochrome P450
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1739Oral cancer
1781Rheumatoid arthritis
1795Amnionitis
1803Periodontitis
1804Chronic obstructive airway disease
1807Autoimmune disease
1820Kuhnt-Junius degeneration
1825Oligospermia
1863Aplastic anemia
1869Behcet syndrome
1871Hepatitis
1872Chronic simple glaucoma
1901Endometriosis
1902Kidney failure
1904Diabetes mellitus
1914Cerebrovascular disorder
1918Atherosclerosis
1932Pancreatitis
1934Cancer
1969Azoospermia
2019Hepatitis, Autoimmune
2091Hypertension
2050Peptic esophagitis
2057Premature birth
2074Asthma
2102Polycystic ovary syndrome
2123Vitiligo
2164Barrett's esophagus
2207Deafness
2220Dermatitis
Desease Name
leukemia, myeloid
AGING
pneumonia
bronchitis
colorectal cancer
CARDIOVASCULAR
endometriosis
coke-oven toxicity
Birth Weight
prostate cancer
pancreatitis
CANCER
stomach cancer
PHARMACOGENOMIC
leukemia, acute myeloid
nasopharyngeal cancer
benzene toxicity
Asthma
bladder cancer
esophageal cancer
arsenic metabolism
arsenic toxicity
breast cancer
cardiovascular
IMMUNE
non-Hodgkin's lymphoma
chemotherapy toxicity
METABOLIC
Upper aerodigestive tract cancers
colorectal cancer stomach cancer
Hodgkin's disease
lung cancer
azoospermia oligospermia
leukemia
REPRODUCTION
longevity
Fetal Growth Retardation
INFECTION
cytogenetic studies
1-hydroxypyrene, urinary
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C007606 1,2-epoxy-3-(p-nitrophenoxy)propane GSTT1 protein affects the metabolism of 1,2-epoxy-3-(p-nitrophenoxy)propaneaffects metabolic processing 14508638
C007606 1,2-epoxy-3-(p-nitrophenoxy)propane GSTT1 protein affects the metabolism of 1,2-epoxy-3-(p-nitrophenoxy)propaneaffects metabolic processing 15882759
15683365
C007606 1,2-epoxy-3-(p-nitrophenoxy)propane GSTT1 protein affects the metabolism of 1,2-epoxy-3-(p-nitrophenoxy)propaneaffects metabolic processing 17827337
9854036
C007606 1,2-epoxy-3-(p-nitrophenoxy)propane GSTT1 protein affects the metabolism of 1,2-epoxy-3-(p-nitrophenoxy)propaneaffects metabolic processing 1848757
C007606 1,2-epoxy-3-(p-nitrophenoxy)propane GSTT1 protein affects the metabolism of and results in decreased activity of 1,2-epoxy-3-(p-nitrophenoxy)propaneaffects metabolic processing|decreases activity 8951341
C007606 1,2-epoxy-3-(p-nitrophenoxy)propane GSTT1 protein affects the metabolism of and results in decreased susceptibility to 1,2-epoxy-3-(p-nitrophenoxy)propaneaffects metabolic processing|decreases response to substance 7578934
C031763 1,3-butadiene GSTT1 gene polymorphism promotes the reaction [EPHX1 gene polymorphism results in increased susceptibility to 1,3-butadiene]increases reaction|increases response to substance 11238181
C023891 1,3-dichloro-1-propene GSTT1 protein affects the metabolism of and results in increased activity of 1,3-dichloro-1-propeneaffects metabolic processing|increases activity 15790493
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of GSTT1 mRNAdecreases expression 18648102
C027562 4-nitrobenzyl chloride GSTT1 protein affects the metabolism of 4-nitrobenzyl chlorideaffects metabolic processing 15683365
C027562 4-nitrobenzyl chloride GSTT1 protein affects the metabolism of 4-nitrobenzyl chlorideaffects metabolic processing 9854036
C027562 4-nitrobenzyl chloride GSTT1 protein affects the metabolism of 4-nitrobenzyl chlorideaffects metabolic processing 1848757
C110057 4-nitrophenethyl bromide GSTT1 protein affects the metabolism of 4-nitrophenethyl bromideaffects metabolic processing 15683365
C110057 4-nitrophenethyl bromide GSTT1 protein affects the metabolism of 4-nitrophenethyl bromideaffects metabolic processing 1848757
C057269 6-aminochrysene-1,2-dihydrodiol GSTT1 protein affects the metabolism of and results in decreased activity of 6-aminochrysene-1,2-dihydrodiol metaboliteaffects metabolic processing|decreases activity 8951341
C453681 7-amino-4-chloromethylcoumarin GSTT1 protein mutant form results in increased metabolism of 7-amino-4-chloromethylcoumarinincreases metabolic processing 17011574
C008450 7-methylguanine GSTT1 gene polymorphism affects the susceptibility to and affects the metabolism of 7-methylguanineaffects metabolic processing|affects response to substance 15066569
D000082 Acetaminophen Acetaminophen affects the expression of GSTT1 mRNAaffects expression 17562736
D016604 Aflatoxin B1 GSTT1 gene SNP affects the susceptibility to Aflatoxin B1affects response to substance 12907637
D016604 Aflatoxin B1 GSTT1 protein affects the metabolism of and results in decreased activity of Aflatoxin B1 metaboliteaffects metabolic processing|decreases activity 8951341
D000638 Amiodarone Amiodarone affects the expression of GSTT1 mRNAaffects expression 19483382
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GSTT1 mRNAaffects expression 16483693
D001151 Arsenic GSTT1 gene polymorphism affects the susceptibility to Arsenicaffects response to substance 16214926
C006632 arsenic trioxide arsenic trioxide results in decreased expression of GSTT1 mRNAdecreases expression 20458559
C015001 arsenite arsenite results in increased expression of GSTT1 mRNAincreases expression 15345372
D001194 Asbestos GSTT1 protein affects the susceptibility to Asbestosaffects response to substance 17563610
D001241 Aspirin Aspirin results in increased expression of GSTT1 proteinincreases expression 9729437
D001553 Benzbromarone Benzbromarone affects the expression of GSTT1 mRNAaffects expression 19483382
D001554 Benzene GSTM1 gene polymorphism affects the reaction [GSTT1 gene polymorphism affects the reaction [NQO1 gene SNP results in increased susceptibility to Benzene]]affects reaction|increases response to substance 17178637
D001554 Benzene GSTT1 gene polymorphism affects the susceptibility to Benzeneaffects response to substance 15226677
15591089
15256146
D001554 Benzene GSTT1 gene polymorphism results in increased susceptibility to Benzeneincreases response to substance 15748501
17178637
17119198
15226677
D001554 Benzene GSTT1 protein affects the metabolism of Benzeneaffects metabolic processing 15226677
D001554 Benzene GSTT1 protein affects the susceptibility to Benzeneaffects response to substance 12460800
D001554 Benzene GSTT1 protein polymorphism affects the chemical synthesis of Benzene metaboliteaffects chemical synthesis 15935803
D001554 Benzene GSTT1 protein polymorphism affects the metabolism of [Benzene co-treated with Glutathione]affects cotreatment|affects metabolic processing 15533900
D001554 Benzene GSTT1 protein polymorphism affects the susceptibility to Benzeneaffects response to substance 15533900
15935803
D001554 Benzene GSTT1 protein results in increased metabolism of Benzeneincreases metabolic processing 17885617
C032036 bromobenzene bromobenzene results in decreased expression of GSTT1 mRNAdecreases expression 15056800
C025191 bromodichloromethane GSTT1 protein results in increased metabolism of bromodichloromethaneincreases metabolic processing 12588193
C025191 bromodichloromethane GSTT1 protein results in increased metabolism of bromodichloromethaneincreases metabolic processing 12588193
C025191 bromodichloromethane GSTT1 protein affects the metabolism of [bromodichloromethane co-treated with Glutathione]affects cotreatment|affects metabolic processing 14998683
C025191 bromodichloromethane GSTT1 protein results in increased metabolism of bromodichloromethaneincreases metabolic processing 12588193
D002084 Butylated Hydroxytoluene Butylated Hydroxytoluene results in increased expression of GSTT1 mRNAincreases expression 15110098
D020122 tert-Butylhydroperoxide GSTT1 protein affects the metabolism of tert-Butylhydroperoxideaffects metabolic processing 9854036
D002087 Butyrates Butyrates results in increased expression of GSTT1 mRNAincreases expression 14674679
D002101 Cacodylic Acid GSTT1 gene affects the susceptibility to Cacodylic Acidaffects response to substance 17431481
D002101 Cacodylic Acid GSTT1 protein affects the metabolism of Cacodylic Acidaffects metabolic processing 17431481
D002246 Carbon Disulfide GSTT1 gene polymorphism affects the metabolism of Carbon Disulfideaffects metabolic processing 17333241
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of GSTT1 mRNAaffects expression 17484886
D002330 Carmustine GSTT1 protein affects the metabolism of Carmustineaffects metabolic processing 17827337
D004390 Chlorpyrifos Chlorpyrifos results in increased expression of GSTT1 mRNAincreases expression 19440498
17452286
D002994 Clofibrate Clofibrate affects the expression of GSTT1 mRNAaffects expression 19483382
D002994 Clofibrate Clofibrate results in increased expression of GSTT1 mRNAincreases expression 12883083
C030123 coumarin coumarin results in increased expression of GSTT1 mRNAincreases expression 10413528
C030123 coumarin coumarin results in increased expression of GSTT1 proteinincreases expression 10413528
C007164 cumene hydroperoxide GSTT1 protein affects the metabolism of cumene hydroperoxideaffects metabolic processing 9854036
C007164 cumene hydroperoxide GSTT1 protein affects the metabolism of cumene hydroperoxideaffects metabolic processing 1848757
D016572 Cyclosporine Cyclosporine results in decreased expression of GSTT1 mRNAdecreases expression 20106945
D003687 Dehydroepiandrosterone Dehydroepiandrosterone results in increased expression of GSTT1 mRNAincreases expression 17823450
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of GSTT1 mRNAaffects cotreatment|decreases expression 16054899
D003907 Dexamethasone Dexamethasone results in decreased expression of GSTT1 mRNAdecreases expression 12971794
D003976 Diazinon Diazinon results in increased expression of GSTT1 mRNAincreases expression 17452286
D015946 Ethylene Dibromide GSTT1 protein affects the metabolism of and results in increased activity of Ethylene Dibromideaffects metabolic processing|increases activity 8565128
D015946 Ethylene Dibromide GSTT1 protein affects the susceptibility to Ethylene Dibromideaffects response to substance 12902151
D015946 Ethylene Dibromide GSTT1 protein results in increased activity of Ethylene Dibromideincreases activity 12505322
D015946 Ethylene Dibromide GSTT1 protein results in increased metabolism of and results in increased activity of Ethylene Dibromideincreases activity|increases metabolic processing 10413528
D002945 Cisplatin GSTT1 gene polymorphism affects the susceptibility to [Paclitaxel co-treated with Cisplatin]affects cotreatment|affects response to substance 12851839
D004137 Dinitrochlorobenzene GSTT1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione]affects cotreatment|affects metabolic processing 15950511
C007366 erythritol anhydride GSTT1 gene polymorphism affects the susceptibility to erythritol anhydrideaffects response to substance 12694746
15036125
C007366 erythritol anhydride GSTT1 gene polymorphism results in increased susceptibility to erythritol anhydrideincreases response to substance 17078101
C007366 erythritol anhydride GSTT1 protein affects the metabolism of and results in increased activity of erythritol anhydrideaffects metabolic processing|increases activity 8565128
C007366 erythritol anhydride GSTT1 protein results in decreased activity of erythritol anhydridedecreases activity 12694746
C007366 erythritol anhydride GSTT1 protein affects the metabolism of and results in increased activity of erythritol anhydrideaffects metabolic processing|increases activity 7578934
D004958 Estradiol [Progesterone co-treated with Estradiol] results in decreased expression of GSTT1 mRNAaffects cotreatment|decreases expression 17404688
D004958 Estradiol Estradiol results in decreased expression of GSTT1 mRNAdecreases expression 14664709
D002393 Estrogens, Catechol GSTT1 protein affects the metabolism of Estrogens, Catechol metaboliteaffects metabolic processing 15455371
D000431 Ethanol GSTT1 gene polymorphism affects the susceptibility to Ethanolaffects response to substance 15932176
D005001 Ethionine Ethionine affects the expression of GSTT1 mRNAaffects expression 19483382
D005027 Ethylene Oxide GSTT1 protein affects the abundance of Ethylene Oxide metaboliteaffects abundance 17416773
D005038 Ethylnitrosourea GSTT1 gene polymorphism affects the susceptibility to Ethylnitrosoureaaffects response to substance 17158087
D005472 Fluorouracil Fluorouracil results in increased expression of GSTT1 proteinincreases expression 16803524
15585135
D005557 Formaldehyde [GSTT1 protein affects the metabolism of Methylene Chloride] which results in increased abundance of Formaldehydeaffects metabolic processing|increases abundance 16765633
D005938 Glucocorticoids GSTT1 gene polymorphism affects the susceptibility to Glucocorticoidsaffects response to substance 15457183
D005978 Glutathione GSTT1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione]affects cotreatment|affects metabolic processing 15950511
D005978 Glutathione GSTT1 protein affects the metabolism of Glutathioneaffects metabolic processing 14727918
D005978 Glutathione GSTT1 protein polymorphism affects the metabolism of [Benzene co-treated with Glutathione]affects cotreatment|affects metabolic processing 15533900
D005978 Glutathione GSTT1 protein affects the metabolism of [bromodichloromethane co-treated with Glutathione]affects cotreatment|affects metabolic processing 14998683
D005978 Glutathione GSTT1 protein affects the metabolism of Glutathioneaffects metabolic processing 14727918
D006016 Glycolates Glycolates analog binds to and results in decreased activity of GSTT1 proteinaffects binding|decreases activity 6686184
D006540 Herbicides Herbicides binds to and results in decreased activity of GSTT1 proteinaffects binding|decreases activity 6686184
D017313 Fenretinide Fenretinide results in decreased expression of GSTT1 mRNAdecreases expression 16467112
D006846 Hydrocarbons, Halogenated GSTT1 protein affects the metabolism of and results in increased activity of Hydrocarbons, Halogenatedaffects metabolic processing|increases activity 11511186
D006846 Hydrocarbons, Halogenated GSTT1 protein affects the metabolism of and results in increased activity of Hydrocarbons, Halogenatedaffects metabolic processing|increases activity 11511186
D006846 Hydrocarbons, Halogenated GSTT1 protein affects the metabolism of Hydrocarbons, Halogenatedaffects metabolic processing 8625454
D007052 Ibuprofen Ibuprofen results in increased expression of GSTT1 proteinincreases expression 9729437
C016517 indole-3-carbinol indole-3-carbinol results in increased expression of GSTT1 mRNAincreases expression 10413528
C016517 indole-3-carbinol indole-3-carbinol results in increased expression of GSTT1 proteinincreases expression 10413528
D007213 Indomethacin Indomethacin results in increased expression of GSTT1 proteinincreases expression 9729437
D007306 Insecticides GSTT1 gene polymorphism affects the susceptibility to Insecticidesaffects response to substance 12930676
D007306 Insecticides GSTT1 protein affects the metabolism of and results in decreased alkylation of Insecticidesaffects metabolic processing|decreases alkylation 15103050
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of GSTT1 mRNAaffects cotreatment|decreases expression 16054899
D007538 Isoniazid GSTT1 gene polymorphism affects the susceptibility to [Isoniazid co-treated with Rifampin]affects cotreatment|affects response to substance 20485159
D007538 Isoniazid GSTT1 gene polymorphism results in increased susceptibility to [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide]affects cotreatment|increases response to substance 18397238
D017879 Isothiocyanates GSTT1 gene polymorphism affects the susceptibility to Isothiocyanatesaffects response to substance 14693750
D008054 Lipid Peroxides GSTT1 protein affects the metabolism of and results in decreased susceptibility to Lipid Peroxidesaffects metabolic processing|decreases response to substance 9576856
C005218 methyl bromide GSTT1 protein results in increased metabolism of methyl bromideincreases metabolic processing 11305778
D008737 Methyl Chloride GSTT1 protein polymorphism affects the metabolism of and affects the susceptibility to Methyl Chlorideaffects metabolic processing|affects response to substance 11218045
D008737 Methyl Chloride GSTT1 protein results in increased metabolism of Methyl Chlorideincreases metabolic processing 11305778
C027947 methylene bromide GSTT1 protein affects the metabolism of and results in increased activity of methylene bromideaffects metabolic processing|increases activity 8565128
C027947 methylene bromide GSTT1 protein affects the metabolism of methylene bromideaffects metabolic processing 14727918
C027947 methylene bromide GSTT1 protein affects the metabolism of and results in increased activity of methylene bromideaffects metabolic processing|increases activity 11511186
C027947 methylene bromide GSTT1 protein affects the metabolism of methylene bromideaffects metabolic processing 14727918
D008752 Methylene Chloride GSTT1 protein affects the metabolism of Methylene Chlorideaffects metabolic processing 15683365
14727918
D008752 Methylene Chloride GSTT1 protein results in increased metabolism of Methylene Chlorideincreases metabolic processing 11446825
12054768
D008752 Methylene Chloride GSTT1 protein affects the metabolism of and results in increased activity of Methylene Chlorideaffects metabolic processing|increases activity 8761485
15683365
D008752 Methylene Chloride GSTT1 protein affects the metabolism of Methylene Chlorideaffects metabolic processing 8670055
17827337
9854036
D008752 Methylene Chloride [GSTT1 protein affects the metabolism of Methylene Chloride] which results in increased abundance of Formaldehydeaffects metabolic processing|increases abundance 16765633
D008752 Methylene Chloride GSTT1 protein affects the metabolism of Methylene Chlorideaffects metabolic processing 8670055
1848757
D008752 Methylene Chloride GSTT1 protein affects the metabolism of Methylene Chlorideaffects metabolic processing 14727918
D008752 Methylene Chloride GSTT1 protein results in increased metabolism of and results in increased activity of Methylene Chlorideincreases activity|increases metabolic processing 10413528
D008752 Methylene Chloride GSTT1 protein results in increased metabolism of Methylene Chlorideincreases metabolic processing 11453994
D008743 Methyl Parathion GSTT1 protein affects the metabolism of and results in decreased alkylation of Methyl Parathionaffects metabolic processing|decreases alkylation 15103050
C020300 monomethylarsonic acid GSTT1 protein affects the methylation of monomethylarsonic acidaffects methylation 17431481
C058346 N-(4-methoxyphenyl)retinamide N-(4-methoxyphenyl)retinamide results in decreased expression of GSTT1 mRNAdecreases expression 16467112
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in increased expression of GSTT1 mRNAincreases expression 12883083
C026209 oltipraz oltipraz affects the localization of GSTT1 proteinaffects localization 10413528
D009853 Omeprazole Omeprazole affects the expression of GSTT1 mRNAaffects expression 19483382
D017239 Paclitaxel GSTT1 gene polymorphism affects the susceptibility to [Paclitaxel co-treated with Cisplatin]affects cotreatment|affects response to substance 12851839
D010575 Pesticides GSTT1 gene polymorphism affects the susceptibility to Pesticidesaffects response to substance 14504370
15922524
D010634 Phenobarbital Phenobarbital results in increased expression of GSTT1 mRNAincreases expression 9854036
D010634 Phenobarbital Phenobarbital results in increased expression of GSTT1 mRNAincreases expression 10413528
D010634 Phenobarbital Phenobarbital results in increased expression of GSTT1 proteinincreases expression 10413528
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of GSTT1 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid affects the expression of GSTT1 mRNAaffects expression 19483382
D010894 Piroxicam Piroxicam results in increased expression of GSTT1 proteinincreases expression 9729437
D028321 Plant Preparations GSTT1 gene polymorphism affects the susceptibility to Plant Preparationsaffects response to substance 17602170
D011084 Polycyclic Hydrocarbons, Aromatic GSTT1 gene polymorphism affects the susceptibility to Polycyclic Hydrocarbons, Aromaticaffects response to substance 12807751
D011084 Polycyclic Hydrocarbons, Aromatic GSTT1 protein affects the metabolism of and results in decreased activity of Polycyclic Hydrocarbons, Aromaticaffects metabolic processing|decreases activity 15122594
D011084 Polycyclic Hydrocarbons, Aromatic GSTT1 protein results in decreased activity of Polycyclic Hydrocarbons, Aromaticdecreases activity 15122594
D011374 Progesterone [Progesterone co-treated with Estradiol] results in decreased expression of GSTT1 mRNAaffects cotreatment|decreases expression 17404688
D011441 Propylthiouracil Propylthiouracil affects the expression of GSTT1 mRNAaffects expression 19483382
D011718 Pyrazinamide GSTT1 gene polymorphism results in increased susceptibility to [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide]affects cotreatment|increases response to substance 18397238
C031280 pyrazole pyrazole results in decreased expression of GSTT1 mRNAdecreases expression 17945193
D011794 Quercetin Quercetin results in decreased expression of GSTT1 mRNAdecreases expression 16455785
D012293 Rifampin GSTT1 gene polymorphism affects the susceptibility to [Isoniazid co-treated with Rifampin]affects cotreatment|affects response to substance 20485159
D012293 Rifampin GSTT1 gene polymorphism results in increased susceptibility to [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide]affects cotreatment|increases response to substance 18397238
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of GSTT1 mRNAaffects cotreatment|decreases expression 16054899
C058186 S-hexylglutathione-sepharose S-hexylglutathione-sepharose binds to GSTT1 proteinaffects binding 2337594
D020123 Sirolimus GSTT1 gene mutant form results in increased susceptibility to Sirolimusincreases response to substance 12916871
C017947 sodium arsenite sodium arsenite affects the expression of GSTT1 mRNAaffects expression 16507464
C017947 sodium arsenite [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTT1 mRNAaffects cotreatment|increases expression 16368122
C017947 sodium arsenite sodium arsenite results in increased expression of GSTT1 mRNAincreases expression 17451858
D012982 Sodium, Dietary GSTT1 gene polymorphism affects the susceptibility to Sodium, Dietaryaffects response to substance 14696128
D018038 Sodium Selenite Sodium Selenite results in increased expression of GSTT1 mRNAincreases expression 16705456
C053003 S-phenyl-N-acetylcysteine GSTT1 protein polymorphism affects the chemical synthesis of S-phenyl-N-acetylcysteineaffects chemical synthesis 15533900
15935803
D013241 Sterigmatocystin GSTT1 protein affects the metabolism of and results in decreased activity of Sterigmatocystin metaboliteaffects metabolic processing|decreases activity 8951341
D020058 Styrene GSTM1 gene polymorphism promotes the reaction [GSTT1 gene polymorphism results in increased susceptibility to Styrene]increases reaction|increases response to substance 12016165
D020058 Styrene GSTT1 gene polymorphism affects the susceptibility to Styreneaffects response to substance 14751678
12717779
D020058 Styrene GSTT1 gene polymorphism results in increased susceptibility to Styreneincreases response to substance 16424821
12016165
C013690 styrene oxide GSTT1 gene polymorphism results in increased susceptibility to styrene oxideincreases response to substance 12016165
C013690 styrene oxide GSTT1 protein affects the susceptibility to styrene oxideaffects response to substance 15468052
D013457 Sulfur Compounds GSTT1 gene polymorphism affects the susceptibility to Sulfur Compoundsaffects response to substance 15033463
D013467 Sulindac Sulindac results in increased expression of GSTT1 proteinincreases expression 9729437
C446685 systhane systhane results in increased expression of GSTT1 mRNAincreases expression 16730040
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of GSTT1 mRNAincreases expression 11272835
D013755 Tetradecanoylphorbol Acetate [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTT1 mRNAaffects cotreatment|increases expression 16368122
D013827 Thiabendazole Thiabendazole results in increased expression of GSTT1 mRNAincreases expression 15110098
D013853 Thioacetamide Thioacetamide affects the expression of GSTT1 mRNAaffects expression 19483382
C032910 triadimefon triadimefon results in increased expression of GSTT1 mRNAincreases expression 16730040
D014303 Trinitrotoluene Trinitrotoluene affects the expression of GSTT1 mRNAaffects expression 21346803
D014315 Triterpenes Triterpenes results in increased expression of GSTT1 mRNAincreases expression 18544911
C057693 troglitazone GSTT1 gene polymorphism affects the susceptibility to troglitazoneaffects response to substance 12732844
D014415 Tunicamycin Tunicamycin results in decreased expression of GSTT1 mRNAdecreases expression 17127020
D014752 Vinyl Chloride [GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] results in increased susceptibility to Vinyl Chlorideaffects cotreatment|increases response to substance 16977343
D014752 Vinyl Chloride GSTT1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]affects mutagenesis|affects reaction 16097394
D014752 Vinyl Chloride GSTT1 gene polymorphism results in increased susceptibility to Vinyl Chlorideincreases response to substance 16270392
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Sulindac 4.5714745880
MESH:D000014 Abnormalities, Drug-Induced Ethanol 13.0518926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 13.056195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 13.0515322242 11752688 14514962
MESH:D000014 Abnormalities, Drug-Induced Trinitrotoluene 13.057525203
MESH:D000022 Abortion, Spontaneous bromodichloromethane 5.9614691210 12970577
MESH:D000138 Acidosis Ammonium Chloride 7.4618287403
MESH:D000138 Acidosis Ethanol 7.4611192467
MESH:D058186 Acute Kidney Injury Cisplatin 9.9017670903 12690470 15814532
MESH:D058186 Acute Kidney Injury Ibuprofen 9.906375363
MESH:D058186 Acute Kidney Injury Sulindac 9.907897758
MESH:D055371 Acute Lung Injury pirinixic acid 2.2818653653
MESH:D000230 Adenocarcinoma arsenic trioxide 18.4619825857 11798837
MESH:D000230 Adenocarcinoma Cisplatin 18.4617638652 11798837
MESH:D000230 Adenocarcinoma Estradiol 18.4611473722
MESH:D000230 Adenocarcinoma Fenretinide 18.4610697514
MESH:D000230 Adenocarcinoma Fluorouracil 18.4617638652
MESH:D000230 Adenocarcinoma Ibuprofen 18.4610697514
MESH:D000230 Adenocarcinoma Indomethacin 18.4616537180
MESH:D000230 Adenocarcinoma Sulindac 18.4611910360
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 11.023712494
MESH:D000236 Adenoma Ethylnitrosourea 11.026695378
MESH:D000236 Adenoma Indomethacin 11.0211497255
MESH:D000236 Adenoma Sulindac 11.0210223192
MESH:D018248 Adenoma, Liver Cell Phenobarbital 12.0717620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 12.0716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 12.0716835633
MESH:D011125 Adenomatous Polyposis Coli Sulindac 3.7917611924 11535846 16460482 11874996 15623613 12394442 19003578
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.7715276417
MESH:D000309 Adrenal Insufficiency Dehydroepiandrosterone 4.8717302879
MESH:D018246 Adrenocortical Adenoma Arsenic 10.7217306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 10.7216712894 17306315
MESH:D000382 Agricultural Workers' Diseases Chlorpyrifos 13.3516611668 17119214 11874814
MESH:D000382 Agricultural Workers' Diseases Diazinon 13.3516487989
MESH:D000382 Agricultural Workers' Diseases methyl bromide 13.3512661182
MESH:D000382 Agricultural Workers' Diseases Pesticides 13.3517119214
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.3915451039 15451040
MESH:D016301 Alveolar Bone Loss Indomethacin 4.4417225004
MESH:D000544 Alzheimer Disease Ibuprofen 4.9718351690
MESH:D000544 Alzheimer Disease Indomethacin 4.9715579461 17627676
MESH:D000544 Alzheimer Disease rosiglitazone 4.9719621015
MESH:D000707 Anaphylaxis Ibuprofen 4.359532969
MESH:D000740 Anemia Fluorouracil 6.0015504547 16511603 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.0011748828
MESH:D000741 Anemia, Aplastic Benzene 3.6214761424 11369114 17661222
MESH:D000743 Anemia, Hemolytic Quercetin 3.4117084956
MESH:D000747 Anemia, Hypochromic 1,3-dichloro-1-propene 6.9810620473
MESH:D000799 Angioedema Acetaminophen 2.9210982225
MESH:D000853 Anophthalmos Ethanol 3.9315513904
MESH:D001008 Anxiety Disorders Ethanol 3.2511141031
MESH:D001014 Aortic Aneurysm Indomethacin 3.9810231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 3.9810388637
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.0018218290 18057881 20041841
MESH:D020261 Arsenic Poisoning Arsenic 2.5212569548 18414634 16251483 16835338
MESH:D018771 Arthralgia Indomethacin 4.242160914
MESH:D001169 Arthritis, Experimental Dexamethasone 2.9117659584
MESH:D001172 Arthritis, Rheumatoid Indomethacin 2.5411248219
MESH:D001195 Asbestosis marker/mechanism 17563610
MESH:D055963 Asthma, Aspirin-Induced Aspirin 3.9220485159 12372130
MESH:D001260 Ataxia Telangiectasia Quercetin 4.0715336622
MESH:D050197 Atherosclerosis Arsenic 10.8012928151 19371607
MESH:D050197 Atherosclerosis Asbestos 10.8018795166
MESH:D050197 Atherosclerosis Carbon Disulfide 10.8010367350 10658303
MESH:D050197 Atherosclerosis Lipid Peroxides 10.8016632123
MESH:D001281 Atrial Fibrillation Amiodarone 3.1719698954 18651412
MESH:D001289 Attention Deficit Disorder with Hyperactivity Pesticides 4.7920478945
MESH:D001321 Autistic Disorder Acetaminophen 2.3318445737
MESH:D001321 Autistic Disorder Glutathione 2.3318929414 16917939 19267885 19056591
MESH:D001321 Autistic Disorder Pesticides 2.3317938740
MESH:D001321 Autistic Disorder Sirolimus 2.3321115397
MESH:D001327 Autoimmune Diseases Quercetin 3.5219761891
MESH:D001477 Bartter Syndrome Indomethacin 4.0910684365
MESH:D001649 Bile Duct Diseases bromodichloromethane 6.308717228
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.0911289319 1440618
MESH:D001661 Biliary Tract Neoplasms Vinyl Chloride 5.9411024202
MESH:D001778 Blood Coagulation Disorders Amiodarone 47.9819483382
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 47.9816206674
MESH:D001778 Blood Coagulation Disorders Benzbromarone 47.9819483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 47.9819483382
MESH:D001778 Blood Coagulation Disorders Ethionine 47.9819483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 47.9819483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 47.9819483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 47.9819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 47.9812125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 47.9819483382
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.8715340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.1115746008
MESH:D001855 Bone Marrow Diseases Benzene 4.3016183116
MESH:D019046 Bone Marrow Neoplasms Cisplatin 3.9614601052
MESH:D001859 Bone Neoplasms Paclitaxel 3.7215867366
MESH:D001913 Bowen's Disease Sulindac 4.4311207687
MESH:D001927 Brain Diseases Ethylnitrosourea 4.0614991843
MESH:D001929 Brain Edema Indomethacin 4.1011481608
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.4117868700
MESH:D001930 Brain Injuries Progesterone 3.3715665606 15845082 15380490
MESH:D002545 Brain Ischemia Ibuprofen 7.5815837124
MESH:D002545 Brain Ischemia Indomethacin 7.5812524144
MESH:D001932 Brain Neoplasms 1,3-butadiene 28.5416860786
MESH:D001932 Brain Neoplasms Aspirin 28.5415481559
MESH:D001932 Brain Neoplasms Carmustine 28.5416187019
MESH:D001932 Brain Neoplasms Ethylene Oxide 28.5412562636
MESH:D001932 Brain Neoplasms Ethylnitrosourea 28.5416436596 15144691 16357521 16651633 18412241
MESH:D001932 Brain Neoplasms Fenretinide 28.5416187019
MESH:D001932 Brain Neoplasms Vinyl Chloride 28.5412562636
MESH:D001943 Breast Neoplasms 1,3-butadiene 22.1311921183 12165863
MESH:D001943 Breast Neoplasms Aspirin 22.1315161893
MESH:D001943 Breast Neoplasms Benzene 22.1317162533 11921183
MESH:D001943 Breast Neoplasms Cacodylic Acid 22.1317474063
MESH:D001943 Breast Neoplasms Cisplatin 22.1318382427 19526202
MESH:D001943 Breast Neoplasms Estradiol 22.1316675129 12948864 18497071 17018787 19861407 17289903 14630087 17261762
MESH:D001943 Breast Neoplasms Estrogens, Catechol 22.1317261777
MESH:D001943 Breast Neoplasms Ethylene Dibromide 22.1311921183
MESH:D001943 Breast Neoplasms Ethylene Oxide 22.1317162533 11921183
MESH:D001943 Breast Neoplasms Fenretinide 22.1316601279
MESH:D001943 Breast Neoplasms Fluorouracil 22.1315136595 18357371 19217205 16110121 16595493 18608205 16557594
MESH:D001943 Breast Neoplasms Formaldehyde 22.1315986119
MESH:D001943 Breast Neoplasms indole-3-carbinol 22.1316082211
MESH:D001943 Breast Neoplasms Indomethacin 22.1317401462
MESH:D001943 Breast Neoplasms Methylene Chloride 22.1315986119
MESH:D001943 Breast Neoplasms Paclitaxel 22.1316115903 16244791 18223236 18323546 18234424 16273361 11325840 15136595
MESH:D001943 Breast Neoplasms Plant Preparations 22.1317398067
MESH:D001943 Breast Neoplasms Progesterone 22.1315562024 17614352 16175315
MESH:D001943 Breast Neoplasms Quercetin 22.1318628248
MESH:D001943 Breast Neoplasms Styrene 22.1315986119
MESH:D001943 Breast Neoplasms Sulindac 22.1316642371
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 22.1320435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.4711589617
MESH:D002056 Burns Ethanol 8.4316374292
MESH:D002056 Burns Indomethacin 8.4310459503
MESH:D002100 Cachexia Ibuprofen 9.6515141370
MESH:D002100 Cachexia Indomethacin 9.6515141370 15625704 11239499 16537180
MESH:D002105 Cadmium Poisoning Quercetin 4.6216962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.5516111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 2.9010355542 16227642 16097048 15721981 3786805 15700767 16050911 15673190 16011737 16192424 18705752 16124888
MESH:D002276 Carcinoid Tumor Fluorouracil 3.7416051944
MESH:D002277 Carcinoma Fluorouracil 5.6817121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 5.6816835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 2.9915504454 17687452
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 46.853581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 46.853084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 46.8521507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Arsenic 46.8517306315 16507464
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 46.8515553829 14691202 15073043 16217749 11135700
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 46.851701930
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 46.8518788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 46.8517982673
MESH:D006528 Carcinoma, Hepatocellular Estradiol 46.8516924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 46.8515289165 15763234 18788625
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 46.8516270382 17159502
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 46.8516332177 17971768 17045692 17088986 16799960 18930000
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 46.8516391822
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 46.8516313753
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 46.851701930 17173139 20007298 20935162 6705139
MESH:D006528 Carcinoma, Hepatocellular Quercetin 46.8512508355 19519916
MESH:D006528 Carcinoma, Hepatocellular Sirolimus 46.8519335982
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 46.8516507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 46.8517997003
MESH:D006528 Carcinoma, Hepatocellular Vinyl Chloride 46.8512828392 15289165 12958735 10699891
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 3.8211053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.4418791128 14736730 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.6316685392 12023789
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.0617234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 3.9519014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 7.697296757
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 7.6918695887
MESH:D002292 Carcinoma, Renal Cell Indomethacin 7.6917341418
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.3012490120
MESH:D002294 Carcinoma, Squamous Cell marker/mechanism 17173682
MESH:D002294 Carcinoma, Squamous Cell Arsenic 29.3917687452 15504454 18922899
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 29.3918337622 17066447 6189445
MESH:D002294 Carcinoma, Squamous Cell erythritol anhydride 29.3910925838
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 29.3916274795
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 29.3916757204 17066447 18986760 16280240
MESH:D002294 Carcinoma, Squamous Cell Glutathione 29.3917015178
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 29.3912636206 15482327
MESH:D002294 Carcinoma, Squamous Cell Plant Preparations 29.3917418620
MESH:D002294 Carcinoma, Squamous Cell Sirolimus 29.3919435901
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 29.3918572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 29.3918922899
MESH:D002295 Carcinoma, Transitional Cell Arsenic 3.2718640142
MESH:D006332 Cardiomegaly Ethanol 7.9919332462
MESH:D006332 Cardiomegaly Quercetin 7.9919794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 7.9918670907 18850075 16120746
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.4815710769 19225199
MESH:D002318 Cardiovascular Diseases Arsenic 5.6217938729 19152805 15738583
MESH:D002318 Cardiovascular Diseases Plant Preparations 5.6216862667
MESH:D002340 Carotid Artery Diseases Arsenic 3.5118022660 16973168
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.1718974383
MESH:D016893 Carotid Stenosis Plant Preparations 5.2215158307
MESH:D002386 Cataract Acetaminophen 5.4410977129
MESH:D002386 Cataract Trinitrotoluene 5.4415817613 14694615
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 17.527505956
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 17.521399818
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 17.5212371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 17.5218566989
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 17.5216003739
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 17.5220056578 19524636
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.364080065
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 5.0517160924
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 4.5616154183
MESH:D002637 Chest Pain Omeprazole 4.1815447763
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 6.9116835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 6.9118291259
MESH:D002761 Cholangitis 1-Naphthylisothiocyanate 5.2712912871
MESH:D002764 Cholecystitis Indomethacin 4.2411181007
MESH:D002779 Cholestasis 1-Naphthylisothiocyanate 13.3718164287 18590720 15913567 16629650 15500046 12927374 19486331 7624871
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.3719486331 9022650
MESH:D002779 Cholestasis Cyclosporine 13.3719486331
MESH:D002779 Cholestasis pirinixic acid 13.3719176532
MESH:D002780 Cholestasis, Intrahepatic 1-Naphthylisothiocyanate 4.9310220858 19407337
MESH:D019457 Chromosome Breakage Sodium Selenite 3.8615894690
MESH:D016770 Ciliophora Infections Formaldehyde 4.7312113305
MESH:D002971 Cleft Lip Ethanol 3.0215513904
MESH:D002972 Cleft Palate Ethanol 7.1015513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 7.1012621046 8697196 15668235 15340226 16354765
MESH:D002972 Cleft Palate triadimefon 7.1016781842
MESH:D003093 Colitis, Ulcerative Dinitrochlorobenzene 3.4517373747 19159591
MESH:D003110 Colonic Neoplasms arsenite 21.1615037631
MESH:D003110 Colonic Neoplasms Aspirin 21.1612411196
MESH:D003110 Colonic Neoplasms bromodichloromethane 21.1614668109
MESH:D003110 Colonic Neoplasms Butyrates 21.1615936596
MESH:D003110 Colonic Neoplasms Dexamethasone 21.1615824018
MESH:D003110 Colonic Neoplasms Fluorouracil 21.1616340194 15001691 17018589 16510598 17172411 18772588 17169374 17725105 17016597 17287894
MESH:D003110 Colonic Neoplasms Indomethacin 21.1615963497 15625704 15786552 11260862 15637740 15936596
MESH:D003110 Colonic Neoplasms Piroxicam 21.1615824018
MESH:D003110 Colonic Neoplasms Quercetin 21.1616640504 11134977 17191121 19440933 19056647 17148506 15741050
MESH:D003110 Colonic Neoplasms Sulindac 21.1612458338 12902858
MESH:D015179 Colorectal Neoplasms arsenic trioxide 11.6920501625
MESH:D015179 Colorectal Neoplasms Aspirin 11.6917047198
MESH:D015179 Colorectal Neoplasms Cisplatin 11.6915273666
MESH:D015179 Colorectal Neoplasms Fenretinide 11.6917273769
MESH:D015179 Colorectal Neoplasms Fluorouracil 11.6917401013 16391804 18383874 15289873 18802399 17255274 17454858 14970324 20501625 18448328 15148649 17094418 16282729 17016601 16331619 16303861 17695437 17594712 16524972 18509181 18288408 18949393
MESH:D015179 Colorectal Neoplasms Indomethacin 11.6918059344 12606626 11197048 17054584
MESH:D015179 Colorectal Neoplasms Paclitaxel 11.6918802399
MESH:D015179 Colorectal Neoplasms Quercetin 11.6918852136 18095365
MESH:D015179 Colorectal Neoplasms Sulindac 11.6911197048 11076880 18059344 10666051
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 6.6417141729 14669216
MESH:D000013 Congenital Abnormalities Trinitrotoluene 6.6415095906
MESH:D003324 Coronary Artery Disease Plant Preparations 3.5715158307
MESH:D023903 Coronary Restenosis arsenic trioxide 3.3112609071
MESH:D018352 Coronavirus Infections Indomethacin 4.7917302372
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 8.9110525206
MESH:D019465 Craniofacial Abnormalities Benzene 8.9115643154
MESH:D019465 Craniofacial Abnormalities Dexamethasone 8.9117728286
MESH:D019465 Craniofacial Abnormalities Ethanol 8.9115451040 15451039 11873399 19302082 15513904 11198716 10194807
MESH:D019465 Craniofacial Abnormalities Glucocorticoids 8.9118281261
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 8.9110048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities triadimefon 8.9116875885 15834900
MESH:D003490 Cyanosis Trinitrotoluene 4.0318551238
MESH:D003550 Cystic Fibrosis Glutathione 3.6919747007
MESH:D007644 Darier Disease Fluorouracil 3.8816733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.2415213294
MESH:D003872 Dermatitis Benzene 3.8815902427
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 9.598156756 2524372 12868966 8970840 18759878 14531868 11298694 11906362
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 9.5912438553
MESH:D017449 Dermatitis, Allergic Contact Dinitrochlorobenzene 9.5915491423
MESH:D017449 Dermatitis, Allergic Contact Formaldehyde 9.5915932584 14996049 12081698 16958921 15059100
MESH:D003876 Dermatitis, Atopic pirinixic acid 1.9118249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 2.652952479 3621924
MESH:D009783 Dermatitis, Occupational Vinyl Chloride 4.8010870345
MESH:D003920 Diabetes Mellitus rosiglitazone 6.7917446233
MESH:D003920 Diabetes Mellitus Sodium Selenite 6.7916285004
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 2.9719496084
MESH:D003922 Diabetes Mellitus, Type 1 Dehydroepiandrosterone 3.3216616286
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 7.4919647726
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 7.4912642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 7.4917107852
MESH:D003924 Diabetes Mellitus, Type 2 troglitazone 7.4916023994
MESH:D003925 Diabetic Angiopathies troglitazone 4.7512601628
MESH:D003928 Diabetic Nephropathies Estradiol 2.6319279558
MESH:D003929 Diabetic Neuropathies Progesterone 3.6017187935
MESH:D003930 Diabetic Retinopathy Sulindac 4.3012861449 17621415
MESH:D003967 Diarrhea Dexamethasone 5.457237001
MESH:D003967 Diarrhea Indomethacin 5.457907874 7237001
MESH:D056486 Drug-Induced Liver Injury marker/mechanism 18397238
MESH:D056486 Drug-Induced Liver Injury 1-Naphthylisothiocyanate 36.727624871 17522070 18289764 20133375
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 36.726482804 6679447 8291058 18289764 9328219 18692083 11289319 9653073 7440962 18648102 9022650 16192314 1440618
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 36.7216485898 12705907 17522070 19085960 17562736 19739265 11421492 16109766 15968718 16177239 10663392 16081117 2444490 11461765 18713872 18071297 10774834 11834606 12594235 16227642 19370779 17906064 12540782 19416960 11743745 10915739 14550746 12958197 12153990 14725611 15619225 16781746 16393943 11287661 11739529 14986274 19164858 12392966 19420014 11529661 19923254
MESH:D056486 Drug-Induced Liver Injury Amiodarone 36.7218218290 15265979
MESH:D056486 Drug-Induced Liver Injury bromobenzene 36.7212628495 10092053
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 36.724309450 3732212 21278145 11566570 7440962 10092053 17522070 15027814 10915739 15998439 9327722 3786805 16227642 6623471 15968718 6884620 19085960 19336974 16177239 7179309 2869522 7120509
MESH:D056486 Drug-Induced Liver Injury Ethanol 36.7211566570
MESH:D056486 Drug-Induced Liver Injury Ethylene Dibromide 36.722862719
MESH:D056486 Drug-Induced Liver Injury Isoniazid 36.7217950035 14986274 16770646
MESH:D056486 Drug-Induced Liver Injury pyrazole 36.7212499123
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 36.7215131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 36.7220420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 36.7212963478
MESH:D056486 Drug-Induced Liver Injury Trinitrotoluene 36.7221346803 18551238
MESH:D056486 Drug-Induced Liver Injury troglitazone 36.7214986274
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.1719426721
MESH:D004362 Drug Toxicity Cisplatin 9.7219839026 12649298 15033597 12231392
MESH:D004362 Drug Toxicity Plant Preparations 9.7211033412
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 9.7211462148
MESH:D004374 Ductus Arteriosus, Patent Ibuprofen 10.2118446180 16133044 18450898
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 10.2112774134 18043480 17190690 18446180 16326151 16133044
MESH:D004381 Duodenal Ulcer Indomethacin 6.6611535926 17351913 17329845 11991626 17045617 10671773 17151854 11595415 11595431 16699067 17202747
MESH:D004381 Duodenal Ulcer Omeprazole 6.6616613094 15991576 21218061 17151854
MESH:D050171 Dyslipidemias Clofibrate 3.3616707586
MESH:D004417 Dyspnea Diazinon 3.8916487989
MESH:D004421 Dystonia Phenobarbital 3.151851702
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 5.0518357618
MESH:D004485 Eczema Dexamethasone 3.5912438553
MESH:D004487 Edema Aspirin 24.0517259670
MESH:D004487 Edema Dexamethasone 24.0519703484
MESH:D004487 Edema Indomethacin 24.058985016 16100529 19703484 7907874 10653021 7990266 8273558
MESH:D004487 Edema pirinixic acid 24.0512083418
MESH:D004487 Edema Piroxicam 24.057907874
MESH:D004487 Edema rosiglitazone 24.0512083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 24.0512711302 11000095
MESH:D004487 Edema Tetradecanoylphorbol Acetate 24.0515177302 7812673 11698051 8273558 16716910 8113982 9599246
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 2.9815322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 2.9217692515
MESH:D016889 Endometrial Neoplasms Estradiol 6.0211473722 19148513 18566989
MESH:D016889 Endometrial Neoplasms Estrogens, Catechol 6.0218566989
MESH:D004715 Endometriosis Ibuprofen 20.1215652904
MESH:D004715 Endometriosis Indomethacin 20.1215652904
MESH:D004715 Endometriosis Progesterone 20.1216134523
MESH:D004715 Endometriosis Sulindac 20.1215652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 20.1210568697 9294722
MESH:D019446 Endotoxemia Ibuprofen 7.8611545620
MESH:D019446 Endotoxemia Indomethacin 7.8618509659
MESH:D004751 Enteritis Indomethacin 3.8210567023 17763956 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.0917980183
MESH:D004802 Eosinophilia Indomethacin 3.1911298111
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.223659116
MESH:D004828 Epilepsies, Partial Phenobarbital 2.963922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.3420417680
MESH:D004832 Epilepsy, Absence Phenobarbital 2.766401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.367750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.123659116
MESH:D004938 Esophageal Neoplasms marker/mechanism 17173682
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 25.483581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 25.4812903497
MESH:D004938 Esophageal Neoplasms Cisplatin 25.4815464296 16481741 15173087 16785472 17638652
MESH:D004938 Esophageal Neoplasms Ethanol 25.4816704527
MESH:D004938 Esophageal Neoplasms Fluorouracil 25.4815173087 17638652 16337965 16481741 16785472
MESH:D004938 Esophageal Neoplasms Indomethacin 25.4811005569
MESH:D004938 Esophageal Neoplasms Paclitaxel 25.4816481741
MESH:D004938 Esophageal Neoplasms Piroxicam 25.4815878914
MESH:D004938 Esophageal Neoplasms Plant Preparations 25.4816510608
MESH:D004938 Esophageal Neoplasms Sulindac 25.4812235107
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.2811564622
MESH:D005141 Eyelid Diseases Formaldehyde 5.4514996049
MESH:D005218 Fat Necrosis Thioacetamide 4.7916456712
MESH:D005234 Fatty Liver Amiodarone 38.4614986274
MESH:D005234 Fatty Liver arsenic trioxide 38.4615073043
MESH:D005234 Fatty Liver arsenite 38.4618296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 38.4612795759 61145 15959796 19224547 12631006 17595544 16045604 16239168
MESH:D005234 Fatty Liver Clofibrate 38.4619224547
MESH:D005234 Fatty Liver Cyclosporine 38.4619224547
MESH:D005234 Fatty Liver Ethanol 38.4619236843 16409862 18620774
MESH:D005234 Fatty Liver pirinixic acid 38.4619236843 20131406
MESH:D005234 Fatty Liver rosiglitazone 38.4619196556
MESH:D005234 Fatty Liver Vinyl Chloride 38.4612197357
MESH:D005235 Fatty Liver, Alcoholic Ethanol 4.7417920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.3910194807 15451040 16946407 15513904
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.5711858732
MESH:D005334 Fever Ibuprofen 6.8816997862
MESH:D005334 Fever Indomethacin 6.8817627676 11852909 10431976
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.096705139
MESH:D018221 Fibromatosis, Abdominal Sulindac 4.5714745880
MESH:D018222 Fibromatosis, Aggressive Sulindac 4.2219069698
MESH:D005354 Fibrosarcoma Indomethacin 3.9810962813
MESH:D005355 Fibrosis arsenite 23.1918296743
MESH:D005355 Fibrosis Carbon Tetrachloride 23.1918705752
MESH:D005355 Fibrosis Cyclosporine 23.1912639820 12168785
MESH:D005355 Fibrosis Indomethacin 23.1917994277
MESH:D005355 Fibrosis Quercetin 23.1919474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 23.1920067830
MESH:D005393 Fish Diseases Formaldehyde 4.6912113305
MESH:D005499 Folliculitis Indomethacin 4.2411298111
MESH:D005534 Foot Diseases Arsenic 4.636392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.3916904648
MESH:D005756 Gastritis Acetaminophen 13.7416983495
MESH:D005756 Gastritis Ethanol 13.7415046732
MESH:D005756 Gastritis Indomethacin 13.7415046732
MESH:D005764 Gastroesophageal Reflux Sulindac 4.1411910360
MESH:D005833 Genital Neoplasms, Female sodium arsenite 3.7716452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.318708960
MESH:D005909 Glioblastoma Aspirin 19.2212870263
MESH:D005909 Glioblastoma Carmustine 19.2216187019
MESH:D005909 Glioblastoma Ethylnitrosourea 19.2216436596
MESH:D005909 Glioblastoma Fenretinide 19.2216187019
MESH:D005909 Glioblastoma Indomethacin 19.2212870263
MESH:D005909 Glioblastoma Quercetin 19.2219804834
MESH:D005910 Glioma 1,3-butadiene 13.5515814359
MESH:D005910 Glioma Ethylnitrosourea 13.5516357521 16651633 18412241
MESH:D005910 Glioma Fluorouracil 13.5516145905
MESH:D005910 Glioma Indomethacin 13.5518371953 16487511
MESH:D005910 Glioma Quercetin 13.5517643826
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.5211849393
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.187505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.6710696789
MESH:D006073 Gout Indomethacin 4.4411248219
MESH:D006261 Headache Aspirin 4.0415240983
MESH:D006258 Head and Neck Neoplasms Cisplatin 12.9715464296 15102660
MESH:D006258 Head and Neck Neoplasms Fluorouracil 12.9715162350 15102660 18337622
MESH:D006258 Head and Neck Neoplasms Indomethacin 12.9715482327
MESH:D006258 Head and Neck Neoplasms Sirolimus 12.9719435901
MESH:D034381 Hearing Loss Cisplatin 7.8419898482
MESH:D034381 Hearing Loss Styrene 7.8417420221
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.6415464296
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 1.7710048152 11294989
MESH:D006331 Heart Diseases methyl bromide 5.2116046796
MESH:D006333 Heart Failure pirinixic acid 1.9120558911
MESH:D006390 Hemangioendothelioma Vinyl Chloride 5.2515380572
MESH:D006393 Hemangiopericytoma Vinyl Chloride 5.9410964802
MESH:D006394 Hemangiosarcoma 1,3-butadiene 7.5810930038 2208121
MESH:D006394 Hemangiosarcoma Vinyl Chloride 7.5812211074 12762079 11217710 15999577 12958735 12828392 15989139
MESH:D006402 Hematologic Diseases Benzene 3.8016183116
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.5115720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.5011000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 8.1715633222
MESH:D006501 Hepatic Encephalopathy Thioacetamide 8.1718665440 15929193 17276928
MESH:D006505 Hepatitis 1-Naphthylisothiocyanate 20.2618590720
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 20.266705139
MESH:D006505 Hepatitis Carbon Tetrachloride 20.2619110552 19900420
MESH:D006505 Hepatitis Diazinon 20.2616487989
MESH:D006505 Hepatitis Thioacetamide 20.2616456712
MESH:D019698 Hepatitis C, Chronic Indomethacin 3.8115135802
MESH:D006529 Hepatomegaly Amiodarone 27.2215265979
MESH:D006529 Hepatomegaly Phenobarbital 27.2216109766
MESH:D006529 Hepatomegaly pirinixic acid 27.2218467677 16221962 19772884 19176532
MESH:D006529 Hepatomegaly systhane 27.2217178689 17178688
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 27.2215340226 12621046 16120746
MESH:D006529 Hepatomegaly triadimefon 27.2217178688 17178689
MESH:D006529 Hepatomegaly Trinitrotoluene 27.2215817613
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.667520565
MESH:D006558 Herpes Genitalis Estradiol 4.1015709030
MESH:D006689 Hodgkin Disease Cisplatin 4.9816200630 16170182
MESH:D006689 Hodgkin Disease sodium arsenite 4.9812676792
MESH:D006734 Horse Diseases Thiabendazole 5.3516402567
MESH:D019584 Hot Flashes Estradiol 2.8417088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.128697196 16959395 15340226 18606429 16354765
MESH:D012001 Hyperacusis Aspirin 4.8315240983
MESH:D006930 Hyperalgesia Acetaminophen 12.5616870215
MESH:D006930 Hyperalgesia Ethanol 12.5618783367
MESH:D006930 Hyperalgesia Indomethacin 12.5612727271
MESH:D006930 Hyperalgesia rosiglitazone 12.5612083418
MESH:D034321 Hyperamylasemia Indomethacin 4.7917883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.6216899240
MESH:D006937 Hypercholesterolemia Amiodarone 3.058137927 9751232
MESH:D006940 Hyperemia Indomethacin 4.0912524144
MESH:D006943 Hyperglycemia pirinixic acid 6.5520558911
MESH:D006943 Hyperglycemia Quercetin 6.5511834736 18262572
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 3.6417050553
MESH:D006949 Hyperlipidemias Indomethacin 3.3217546600
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.0515034207
MESH:D006967 Hypersensitivity Butylated Hydroxytoluene 3.7117604070
MESH:D006973 Hypertension Arsenic 17.8516076760 11953799 9931084
MESH:D006973 Hypertension Benzene 17.8517940673
MESH:D006973 Hypertension Cyclosporine 17.8510903974
MESH:D006973 Hypertension Dexamethasone 17.8517042910
MESH:D006973 Hypertension Quercetin 17.8518356687
MESH:D006973 Hypertension Sodium, Dietary 17.8516870316
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 17.8518850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.2015338365
MESH:D006984 Hypertrophy Ibuprofen 8.4016672835
MESH:D006984 Hypertrophy Sirolimus 8.4019211884
MESH:D006987 Hypesthesia Arsenic 4.6316093927
MESH:D007037 Hypothyroidism Amiodarone 8.6618020914 17991464
MESH:D007037 Hypothyroidism Propylthiouracil 8.668137927 18031379
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 9.6518306037
MESH:D007077 Ileal Diseases Indomethacin 9.6518306037 10574470
MESH:D007079 Ileitis Indomethacin 4.4410651667 16133968 10647630
MESH:D007235 Infant, Premature, Diseases Ibuprofen 11.1216133044
MESH:D007235 Infant, Premature, Diseases Indomethacin 11.1216133044
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.5115869954
MESH:D007248 Infertility, Male Diazinon 7.5812948887 16466525
MESH:D007248 Infertility, Male sodium arsenite 7.5815346721 12646999
MESH:D007248 Infertility, Male Trinitrotoluene 7.5812150543
MESH:D007249 Inflammation Dexamethasone 18.618960868 11099482
MESH:D007249 Inflammation Ibuprofen 18.613291741
MESH:D007249 Inflammation Indomethacin 18.617812673 3291741 12568917
MESH:D007249 Inflammation Progesterone 18.6115869954
MESH:D007249 Inflammation rosiglitazone 18.6112083418
MESH:D007249 Inflammation Sulindac 18.613291741
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 18.6112200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 18.6111698051 8273558 15177302 7812673 7562506
MESH:D007251 Influenza, Human Quercetin 3.5916624496
MESH:D007333 Insulin Resistance Estradiol 12.2116393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 12.2116306350
MESH:D007333 Insulin Resistance rosiglitazone 12.2116306350
MESH:D007333 Insulin Resistance Sodium Selenite 12.2114714311
MESH:D007410 Intestinal Diseases Indomethacin 3.4511855677 17329856 10210152 15831440 17994277 11713966 15610444 11686837 18236018
MESH:D007414 Intestinal Neoplasms Piroxicam 7.9410213222
MESH:D007414 Intestinal Neoplasms Sulindac 7.9412351151 12628509 10213222 12584176 10223192 12663524
MESH:D007417 Intestinal Polyps Sulindac 4.1311245490 12394442
MESH:D019586 Intracranial Hypertension Indomethacin 4.4415241188
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.099022650 8074119
MESH:D007569 Jaw Abnormalities Ethanol 12.5315513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 12.5316580747
MESH:D007569 Jaw Abnormalities triadimefon 12.5315992940 15834900
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 9.6518306037
MESH:D007579 Jejunal Diseases Indomethacin 9.6510574470 16133968 18306037
MESH:D007627 Keloid Quercetin 4.0617086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.5115604871
MESH:D007642 Keratosis Arsenic 4.0812749816 16930632
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.2115464296
MESH:D007674 Kidney Diseases Acetaminophen 23.2415629191 12587719
MESH:D007674 Kidney Diseases Cisplatin 23.2412649298 18289764 19839026 12231392 15190930
MESH:D007674 Kidney Diseases Cyclosporine 23.2418776723 10903974 8314463
MESH:D007674 Kidney Diseases Estradiol 23.2415618244
MESH:D007674 Kidney Diseases Ethylene Dibromide 23.2412628311
MESH:D007674 Kidney Diseases Indomethacin 23.2417190690
MESH:D007674 Kidney Diseases Quercetin 23.2416962696
MESH:D007674 Kidney Diseases sodium arsenite 23.2420008137
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 19.266582329
MESH:D007680 Kidney Neoplasms Cyclosporine 19.2612371664
MESH:D007680 Kidney Neoplasms Estradiol 19.2615610895
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 19.2617379185
MESH:D007680 Kidney Neoplasms Fluorouracil 19.2616985049
MESH:D007680 Kidney Neoplasms Vinyl Chloride 19.2612562636
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 3.8711231351
MESH:D007859 Learning Disorders Ethanol 3.3315451040
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 6.1812228301 11703811 10320625
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 6.1819248655
MESH:D007938 Leukemia 1,3-butadiene 10.5016155477
MESH:D007938 Leukemia arsenic trioxide 10.5015070760
MESH:D007938 Leukemia Benzene 10.5018335105 17119257 14694614 15935818
MESH:D007938 Leukemia Quercetin 10.5017468513
MESH:D004915 Leukemia, Erythroblastic, Acute troglitazone 5.2116085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 2.9717077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.4016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 6.1514633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 6.1510785260 16572323 15631656
MESH:D007951 Leukemia, Myeloid arsenic trioxide 6.9519077051
MESH:D007951 Leukemia, Myeloid Benzene 6.9517506065
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 4.6516467208 16968895 17050201 20471514 19850784
MESH:D015470 Leukemia, Myeloid, Acute Benzene 4.6519478238
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 4.6518360721
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 5.5617339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 5.5617649720 15748426 19642359 17869043 15213294 17217047 11468182 16331271 16823087 15622746 16891316 12679006 16112521 16330433 9834237 12018890 19035177 19225113 19075265 11161223 17107899 16966277 12712474 15336539 17712046
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.4816882451
MESH:D007964 Leukocytosis Indomethacin 4.4416537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 4.7917980183
MESH:D007972 Leukoplakia, Oral Fenretinide 5.1216707609
MESH:D017880 Limb Deformities, Congenital Ethanol 3.1117676605
MESH:D008064 Lipidoses Amiodarone 2.8115342952 17567588
MESH:D008080 Liposarcoma Paclitaxel 3.9717353645
MESH:D008101 Liver Abscess, Amebic Indomethacin 4.7911479899
MESH:D008103 Liver Cirrhosis arsenite 14.4718296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 14.4717174718 11408273 16239168 16943688 21278145 17334410 17157831 16221502 11903743
MESH:D008103 Liver Cirrhosis Ethanol 14.4715289165
MESH:D008103 Liver Cirrhosis Phenobarbital 14.4721047994
MESH:D008103 Liver Cirrhosis Vinyl Chloride 14.4712958735 12499459 11679801 15289165 15354062
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.1918295389
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 6.349327722 15034207
MESH:D008105 Liver Cirrhosis, Biliary Sulindac 6.3412468960
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 20.3716248980 15362042 18472332 18481824 12649538 18429990 12632514 18166357 17922224 18156304 18395914 18705752 18277467 15057751 15730626 16027843 18472094 12632512 14748882 15876570 12958196 17640975 12546737 12445421 18251166 17525996 15931870 18420326 15996030 16192424 17481882 18339082 16015684 12667390 17805973 18418968 17714472 17631135 14620537 15123356 17823541 18395095 16136751 17976157 15673190 16033810 15370692 11481614 17869086 16097048 14716496 12609069 12666154 16011737 12898905 17900296 17708605 12586293 15338365 20821823 15818738 18187930 17557913 17944888 14512876 18205269 18412020 13678700 12445418 18279442 17761835 12741479 15925388 10355542 16638106 18263696 18376398 14724832 18210741 14716833 18054572 17721639 15650968 17766677 17565644 15959796 15893842 16116963 18317297 15052691 18006644 17698563 12389079
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 20.3716718785
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 20.3714659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 20.3718166357
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 20.3718194892
MESH:D008106 Liver Cirrhosis, Experimental oltipraz 20.3716544323
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 20.3715474484
MESH:D008106 Liver Cirrhosis, Experimental Plant Preparations 20.3717724770
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 20.3712741479
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 20.3715980055 17347453
MESH:D008106 Liver Cirrhosis, Experimental Sirolimus 20.3717050028
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 20.3712878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 20.3712679928 15474484 16098781 16343077 14739098 16126171 15334695 18295389 15288473 17292413 10677585 15288472 18606216 18380797 16511523 15716488 18263696 18032466 12557150 15316131 18615449 15095483 12085344 18031379 15465738 16248980 12531686 15158331 12891558 11172339 17050028 15078482 18395095 18458672 16489207 17355460 16097051 17629604 11481614 11682029 18416461 15362042 15075984 17127702 12175628
MESH:D008107 Liver Diseases 1-Naphthylisothiocyanate 25.8417184895
MESH:D008107 Liver Diseases Acetaminophen 25.8412587719 12969438 11587558 19014921 16610002 19784758 16611625 19460945
MESH:D008107 Liver Diseases Arsenic 25.8411134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 25.8415830285 17285989 16964402 15720792 16246199
MESH:D008107 Liver Diseases Chlorpyrifos 25.8415991261
MESH:D008107 Liver Diseases Phenobarbital 25.8419363144
MESH:D008107 Liver Diseases Piroxicam 25.8416867024
MESH:D008107 Liver Diseases Sulindac 25.8414986274 16867024
MESH:D008107 Liver Diseases Thioacetamide 25.8415158337 16337175 18374380
MESH:D008107 Liver Diseases triadimefon 25.8419363144
MESH:D008107 Liver Diseases Vinyl Chloride 25.8416270392 15211785
MESH:D008108 Liver Diseases, Alcoholic Ethanol 3.7617207112 17347304
MESH:D017093 Liver Failure Carbon Tetrachloride 3.2715123358
MESH:D017114 Liver Failure, Acute Acetaminophen 11.5717185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 11.5714706259 16899240
MESH:D017114 Liver Failure, Acute Thioacetamide 11.5715633222 17276928 15313186 12479984
MESH:D008113 Liver Neoplasms 1,3-butadiene 41.732208121
MESH:D008113 Liver Neoplasms Aflatoxin B1 41.732125692 18177683 9163691 15890375
MESH:D008113 Liver Neoplasms Arsenic 41.7316368122
MESH:D008113 Liver Neoplasms arsenic trioxide 41.7314682389
MESH:D008113 Liver Neoplasms Butylated Hydroxytoluene 41.7318177683
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 41.7319294768
MESH:D008113 Liver Neoplasms Dehydroepiandrosterone 41.7318709148
MESH:D008113 Liver Neoplasms Fluorouracil 41.7316603448 17045692 15113037 18383874
MESH:D008113 Liver Neoplasms Phenobarbital 41.7319812893 19073162 15975961 8742319 19482888 21047994
MESH:D008113 Liver Neoplasms pirinixic acid 41.7320007298 16377806 15890375
MESH:D008113 Liver Neoplasms Quercetin 41.7318980244
MESH:D008113 Liver Neoplasms sodium arsenite 41.7315276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 41.7316984957
MESH:D008113 Liver Neoplasms triadimefon 41.7319028983
MESH:D008113 Liver Neoplasms Vinyl Chloride 41.7312762079 11679801 10964802 11024202 10629081 12211074 15999577
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 41.63598648 1399818 3712494 6587162
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 41.638603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 41.6320377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 41.6312562636
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 41.6315583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Dehydroepiandrosterone 41.638603461
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 41.631399818 18308698 2563599 6150874 17172636
MESH:D008114 Liver Neoplasms, Experimental Quercetin 41.6319519916
MESH:D008114 Liver Neoplasms, Experimental styrene oxide 41.6312562636
MESH:D008114 Liver Neoplasms, Experimental systhane 41.6317178689
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 41.6312151625
MESH:D008114 Liver Neoplasms, Experimental triadimefon 41.6317178689
MESH:D008114 Liver Neoplasms, Experimental Vinyl Chloride 41.6312562636
MESH:D008133 Long QT Syndrome Amiodarone 5.7517391786 15350150 11989578
MESH:D008133 Long QT Syndrome arsenic trioxide 5.7515213294
MESH:D008171 Lung Diseases Amiodarone 5.2712587719
MESH:D008171 Lung Diseases sodium arsenite 5.2719095001
MESH:D017563 Lung Diseases, Interstitial Amiodarone 8.4018516814
MESH:D017563 Lung Diseases, Interstitial Benzene 8.4014698565
MESH:D008175 Lung Neoplasms 1,3-butadiene 50.072208121 17372256 16860786
MESH:D008175 Lung Neoplasms Aflatoxin B1 50.0714755239
MESH:D008175 Lung Neoplasms Arsenic 50.0717306315 17976673 19168569
MESH:D008175 Lung Neoplasms arsenic trioxide 50.0719825857 11798837
MESH:D008175 Lung Neoplasms arsenite 50.0716809336
MESH:D008175 Lung Neoplasms Asbestos 50.0712111688
MESH:D008175 Lung Neoplasms Benzene 50.0712562636
MESH:D008175 Lung Neoplasms Butylated Hydroxytoluene 50.0711696405 19925653 15390079 18597497 16337739 11246140 19359593
MESH:D008175 Lung Neoplasms Cisplatin 50.076189445 11798837 17225452
MESH:D008175 Lung Neoplasms Dexamethasone 50.0715824018 11195469
MESH:D008175 Lung Neoplasms Ethylene Oxide 50.0717325976 12562636
MESH:D008175 Lung Neoplasms Ethylnitrosourea 50.0717703301 16271038 6695378 16019985
MESH:D008175 Lung Neoplasms Fluorouracil 50.0715246190
MESH:D008175 Lung Neoplasms Indomethacin 50.0716537180 11497255 11053908
MESH:D008175 Lung Neoplasms Methylene Chloride 50.0715172992
MESH:D008175 Lung Neoplasms Piroxicam 50.0715824018 11195469
MESH:D008175 Lung Neoplasms Polycyclic Hydrocarbons, Aromatic 50.0710814675
MESH:D008175 Lung Neoplasms Quercetin 50.0716280456
MESH:D008175 Lung Neoplasms sodium arsenite 50.0716712894 19931552 17306315 17077188 15276417
MESH:D008175 Lung Neoplasms Styrene 50.0712562636
MESH:D008175 Lung Neoplasms Sulindac 50.0715713900 19359593
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 50.0711884234 19555203
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 50.0711807781
MESH:D008175 Lung Neoplasms Vinyl Chloride 50.0712958735 12562636
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 10.2715086387
MESH:D008178 Lupus Erythematosus, Cutaneous Rifampin 10.2711422169
MESH:D008180 Lupus Erythematosus, Systemic Rifampin 3.6311422169
MESH:D008223 Lymphoma 1,3-butadiene 8.8817941976 11980663 18798262 8764131 2208121 9205081 9488045
MESH:D008223 Lymphoma Benzene 8.8817584886 17119257
MESH:D008223 Lymphoma Ethylnitrosourea 8.8815790496
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 3.2114737004
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 3.3214749477
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 4.1615375218
MESH:D015674 Mammary Neoplasms, Animal 1,3-butadiene 21.882208121
MESH:D015674 Mammary Neoplasms, Animal Benzene 21.8812562636
MESH:D015674 Mammary Neoplasms, Animal Ethylene Oxide 21.8812562636
MESH:D015674 Mammary Neoplasms, Animal Styrene 21.8812562636
MESH:D015674 Mammary Neoplasms, Animal Vinyl Chloride 21.8812562636
MESH:D008325 Mammary Neoplasms, Experimental 1,3-butadiene 41.7411921183
MESH:D008325 Mammary Neoplasms, Experimental Benzene 41.7411921183
MESH:D008325 Mammary Neoplasms, Experimental Butylated Hydroxytoluene 41.741500032
MESH:D008325 Mammary Neoplasms, Experimental Dehydroepiandrosterone 41.7416457693
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 41.7417203775 11807958 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental Ethylene Dibromide 41.7411921183
MESH:D008325 Mammary Neoplasms, Experimental Ethylene Oxide 41.7411921183
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 41.7410838139 18041768 10767621
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 41.7410697514
MESH:D008325 Mammary Neoplasms, Experimental Ibuprofen 41.7410697514
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 41.7411408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 41.7416827153
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 41.748985016
MESH:D020149 Manganese Poisoning Estradiol 3.5619453300
MESH:D008545 Melanoma Carmustine 13.5512393984
MESH:D008545 Melanoma Cisplatin 13.5516432458 18332650 18505091 12393984 16248763 11135225 17761969 12883367 16809738 12374674 15577323 18176117 17023156
MESH:D008545 Melanoma Dinitrochlorobenzene 13.5517334785 12202904
MESH:D008545 Melanoma Fenretinide 13.5516270382
MESH:D008545 Melanoma Paclitaxel 13.5512025231 12040289 16342250
MESH:D008545 Melanoma Sirolimus 13.5519282848
MESH:D008545 Melanoma sodium arsenite 13.5516487513 19082730
MESH:D008545 Melanoma Sulindac 13.5516642371
MESH:D018328 Melanoma, Amelanotic Cisplatin 3.8715990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.6819513568
MESH:D008569 Memory Disorders Ethanol 3.3318411066 15451040
MESH:D008579 Meningioma Ethylnitrosourea 5.0517943659
MESH:D008654 Mesothelioma Asbestos 5.2416919927 16564556 18310086 16319530 18709470
MESH:D008654 Mesothelioma Cisplatin 5.2417638057
MESH:D024821 Metabolic Syndrome X rosiglitazone 3.6017261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 3.8616801185
MESH:D008881 Migraine Disorders Aspirin 5.7115240983
MESH:D008881 Migraine Disorders Indomethacin 5.7111903285
MESH:D009062 Mouth Neoplasms Fenretinide 19.1416274795
MESH:D009062 Mouth Neoplasms Fluorouracil 19.1418986760 16757204
MESH:D009062 Mouth Neoplasms Indomethacin 19.1412636206
MESH:D009062 Mouth Neoplasms Plant Preparations 19.1417418620
MESH:D009062 Mouth Neoplasms Sirolimus 19.1419435901
MESH:D009101 Multiple Myeloma marker/mechanism 16949155
MESH:D009101 Multiple Myeloma arsenic trioxide 11.5611468182 19417148 14977855 19549372 15949261
MESH:D009101 Multiple Myeloma Benzene 11.5617119195
MESH:D009101 Multiple Myeloma Dexamethasone 11.5615867202 15744524 16118317
MESH:D009101 Multiple Myeloma Paclitaxel 11.5614749477
MESH:D009135 Muscular Diseases Glucocorticoids 7.9715946989
MESH:D009135 Muscular Diseases pirinixic acid 7.9716239165
MESH:D009164 Mycobacterium Infections Isoniazid 8.7418474467
MESH:D009164 Mycobacterium Infections Rifampin 8.7418474467
MESH:D009181 Mycoses Amiodarone 3.9712754197 17974566
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.7518349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 5.5216882451 16105982
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 5.529809623
MESH:D009203 Myocardial Infarction Aspirin 6.7112692751
MESH:D009203 Myocardial Infarction pirinixic acid 6.7119151258
MESH:D009203 Myocardial Infarction Quercetin 6.7119595682
MESH:D017202 Myocardial Ischemia Arsenic 6.4815371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 6.4812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 9.9016810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 9.9016411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 9.9019207477
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.5717484760
MESH:D009325 Nausea Aspirin 4.2915240983
MESH:D009336 Necrosis Trinitrotoluene 3.8618551238
MESH:D009349 Nematode Infections Thiabendazole 5.4916402567
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.0916624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 6.833581430
MESH:D009362 Neoplasm Metastasis Indomethacin 6.8311053908 11239499 16537180
MESH:D009362 Neoplasm Metastasis Paclitaxel 6.8315867366
MESH:D009369 Neoplasms Cisplatin 18.6916773208
MESH:D009369 Neoplasms Fenretinide 18.6915958647 17353921
MESH:D009369 Neoplasms Fluorouracil 18.6916928823 18600527 18239605
MESH:D009369 Neoplasms pirinixic acid 18.6917405874
MESH:D009369 Neoplasms Piroxicam 18.6916684565
MESH:D009369 Neoplasms Quercetin 18.6915185748
MESH:D009369 Neoplasms sodium arsenite 18.6911559025
MESH:D009369 Neoplasms Vinyl Chloride 18.6911911487
MESH:D009374 Neoplasms, Experimental 1,3-butadiene 19.269488045 9205081 8764131
MESH:D009374 Neoplasms, Experimental erythritol anhydride 19.2610925838
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 19.2616707424
MESH:D009374 Neoplasms, Experimental Indomethacin 19.2610663608 15625704
MESH:D009374 Neoplasms, Experimental sodium arsenite 19.2620056578
MESH:D009389 Neovascularization, Pathologic arsenite 7.1515738583
MESH:D009389 Neovascularization, Pathologic Estradiol 7.1517289903
MESH:D009395 Nephritis, Interstitial Cisplatin 7.8615464296
MESH:D009395 Nephritis, Interstitial Ibuprofen 7.866375363
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.5117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.4918481113 19348381
MESH:D009410 Nerve Degeneration Ibuprofen 3.6610961664
MESH:D009422 Nervous System Diseases Carbon Disulfide 4.9410669001
MESH:D009421 Nervous System Malformations Estradiol 6.5911399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 6.5914600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 15.756679447
MESH:D009436 Neural Tube Defects Arsenic 15.7516620997
MESH:D009436 Neural Tube Defects arsenic trioxide 15.7510525206
MESH:D009436 Neural Tube Defects Benzene 15.7515643154
MESH:D009436 Neural Tube Defects sodium arsenite 15.7512854658
MESH:D009442 Neurilemmoma Ethylnitrosourea 4.5016003739 16651423 17160924
MESH:D009447 Neuroblastoma 1,3-butadiene 5.8415814359
MESH:D009447 Neuroblastoma Cisplatin 5.848761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 9.7418514411
MESH:D019636 Neurodegenerative Diseases Indomethacin 9.7412349958
MESH:D019636 Neurodegenerative Diseases Sulindac 9.7416850258 17266991
MESH:D017599 Neuroectodermal Tumors Cisplatin 3.798761367
MESH:D020078 Neurogenic Inflammation Arsenic 7.8617056641
MESH:D020078 Neurogenic Inflammation Quercetin 7.8617929310
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 4.7716303764
MESH:D020258 Neurotoxicity Syndromes Carbon Disulfide 17.6815315294
MESH:D020258 Neurotoxicity Syndromes Chlorpyrifos 17.6815081274
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 17.6816436463
MESH:D020258 Neurotoxicity Syndromes Insecticides 17.6819861644
MESH:D020258 Neurotoxicity Syndromes Methyl Parathion 17.6819784758
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.059802331
MESH:D009669 Nose Neoplasms Ethylene Dibromide 7.429385384
MESH:D009669 Nose Neoplasms Formaldehyde 7.424038687
MESH:D009765 Obesity pirinixic acid 1.5220558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.246374098
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 15.136482804 4026338
MESH:D009784 Occupational Diseases Benzene 15.1317119257 17479406 16737584 15576619 15935809 17178637 15612468 15913788 15727169
MESH:D009784 Occupational Diseases Trinitrotoluene 15.1314694615 17852074 12819281
MESH:D009784 Occupational Diseases Vinyl Chloride 15.1312061072
MESH:D009837 Oligodendroglioma Ethylnitrosourea 5.0517160924
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.093988306
MESH:D010003 Osteoarthritis Aspirin 9.127009135
MESH:D010003 Osteoarthritis Ibuprofen 9.127009135
MESH:D010003 Osteoarthritis Indomethacin 9.127009135
MESH:D010014 Osteolysis Paclitaxel 4.0715867366
MESH:D010018 Osteomalacia Phenobarbital 3.4617016548
MESH:D015663 Osteoporosis, Postmenopausal Dehydroepiandrosterone 7.6716397352
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 7.6719495926
MESH:D010051 Ovarian Neoplasms 1,3-butadiene 30.432208121
MESH:D010051 Ovarian Neoplasms Arsenic 30.4317306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 30.4312452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Benzene 30.4312562636
MESH:D010051 Ovarian Neoplasms Cisplatin 30.4315464296 19769630 6897625 17225452
MESH:D010051 Ovarian Neoplasms Estradiol 30.4319401270
MESH:D010051 Ovarian Neoplasms Fenretinide 30.4316133793
MESH:D010051 Ovarian Neoplasms Paclitaxel 30.4311161223
MESH:D010051 Ovarian Neoplasms Progesterone 30.4316525653 17393432
MESH:D010051 Ovarian Neoplasms Quercetin 30.4319005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 30.4317306315 15276417
MESH:D010146 Pain Acetaminophen 13.2316870215
MESH:D010146 Pain Aspirin 13.236995502 6363464
MESH:D010146 Pain Ibuprofen 13.233291741
MESH:D010146 Pain Indomethacin 13.2317627676 17440234 3291741 13679232
MESH:D010146 Pain Sulindac 13.233291741
MESH:D010149 Pain, Postoperative Ibuprofen 8.4216678543
MESH:D010149 Pain, Postoperative Indomethacin 8.4212538197 18702446
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 28.8115580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 28.8119003803
MESH:D010190 Pancreatic Neoplasms Ethanol 28.8112384795
MESH:D010190 Pancreatic Neoplasms Fenretinide 28.8115580305
MESH:D010190 Pancreatic Neoplasms Fluorouracil 28.8116500647 16929163 19003803 15113037
MESH:D010190 Pancreatic Neoplasms Ibuprofen 28.8112384795
MESH:D010190 Pancreatic Neoplasms Phenobarbital 28.8116965848
MESH:D010190 Pancreatic Neoplasms Quercetin 28.8116965848
MESH:D010190 Pancreatic Neoplasms Sulindac 28.8116820089 11504793
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 28.8115976015
MESH:D010195 Pancreatitis Indomethacin 6.6117883296 15028970
MESH:D010195 Pancreatitis Insecticides 6.6116258382 3421227
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 10.707296757
MESH:D010212 Papilloma cumene hydroperoxide 10.7012065085 17234724
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 10.708330346 12065085 18404319 18922899
MESH:D010235 Paraganglioma arsenic trioxide 3.3119927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 4.7916537180
MESH:D010300 Parkinson Disease Sirolimus 3.3319682553
MESH:D020734 Parkinsonian Disorders Carbon Disulfide 7.2715019297
MESH:D020734 Parkinsonian Disorders Indomethacin 7.2712349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 4.7911903285
MESH:D010382 Peliosis Hepatis 1-Naphthylisothiocyanate 10.7220133375
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 10.7212520081
MESH:D010437 Peptic Ulcer Indomethacin 4.2411148446
MESH:D010438 Peptic Ulcer Hemorrhage Aspirin 4.6311156591
MESH:D010518 Periodontitis Indomethacin 3.9917225004
MESH:D010523 Peripheral Nervous System Diseases Arsenic 7.1816093927
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 7.1815464296
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.086392382 15371236 16905509
MESH:D020795 Photophobia Aspirin 4.8315240983
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 3.546228378
MESH:D010997 Pleural Neoplasms Cisplatin 4.4217638057
MESH:D011014 Pneumonia Butylated Hydroxytoluene 4.2611893704
MESH:D011041 Poisoning Diazinon 6.6917603234
MESH:D011041 Poisoning Methyl Parathion 6.6917603234
MESH:D017285 Polymyositis Vinyl Chloride 5.9411642524
MESH:D011115 Polyneuropathies Ethylene Oxide 5.278472653
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.6918163543
MESH:D011230 Precancerous Conditions bromodichloromethane 15.5214668109
MESH:D011230 Precancerous Conditions Cyclosporine 15.5212371664
MESH:D011230 Precancerous Conditions Phenobarbital 15.522563599
MESH:D011230 Precancerous Conditions Quercetin 15.5219056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 2.9521297632
MESH:D011248 Pregnancy Complications bromodichloromethane 5.2117344021 14657523 12970577
MESH:D047928 Premature Birth Indomethacin 4.2317000239
MESH:D011297 Prenatal Exposure Delayed Effects Pesticides 7.2517938740
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 7.2511896295 11222880 11118676 11399792
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.0520887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 11275366 16998812 17507624
MESH:D011471 Prostatic Neoplasms Arsenic 3.8616140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.8619131511
MESH:D011471 Prostatic Neoplasms Estradiol 3.8616740699
MESH:D011471 Prostatic Neoplasms Estrogens, Catechol 3.8617261777
MESH:D011471 Prostatic Neoplasms Fenretinide 3.8617024972
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.8619082440 18626508
MESH:D011471 Prostatic Neoplasms Ibuprofen 3.8617409433
MESH:D011471 Prostatic Neoplasms methyl bromide 3.8612661182
MESH:D011471 Prostatic Neoplasms Paclitaxel 3.8617172428 17136230 16729912 16356831
MESH:D011471 Prostatic Neoplasms Quercetin 3.8617292933 14715546
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.8616039940
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.8618760546
MESH:D011507 Proteinuria Arsenic 10.7721343184
MESH:D011507 Proteinuria Ibuprofen 10.776375363
MESH:D011507 Proteinuria Indomethacin 10.7711849393
MESH:D019310 Pseudolymphoma Phenobarbital 3.5712752131
MESH:D011565 Psoriasis Cyclosporine 1.8216882103
MESH:D011658 Pulmonary Fibrosis Amiodarone 4.6611597910 12490602 12832656
MESH:D011658 Pulmonary Fibrosis troglitazone 4.6618162602
MESH:D011928 Raynaud Disease marker/mechanism 16977343
MESH:D011928 Raynaud Disease Vinyl Chloride 5.2416977343
MESH:D012004 Rectal Neoplasms bromodichloromethane 8.0317535441
MESH:D012004 Rectal Neoplasms Fluorouracil 8.0318722050 15538739 16160472 18286688
MESH:D051437 Renal Insufficiency Cisplatin 3.5215464296
MESH:D015427 Reperfusion Injury pirinixic acid 1.8519058328
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 3.1818379247 11700416
MESH:D012135 Respiratory Sounds Chlorpyrifos 7.6911874814 17119214 16611668
MESH:D012135 Respiratory Sounds Pesticides 7.6917119214
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 2.9618990726
MESH:D012140 Respiratory Tract Diseases Chlorpyrifos 8.4416611668 17119214
MESH:D012140 Respiratory Tract Diseases Pesticides 8.4417119214
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 6.683692021
MESH:D012162 Retinal Degeneration Fenretinide 6.6816303925
MESH:D012220 Rhinitis Aspirin 3.5812372130
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.4318045962
MESH:D012509 Sarcoma Vinyl Chloride 4.5412828392
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 7.4616646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 7.4614601052
MESH:D012554 Schistosomiasis japonica Quercetin 4.6216862918
MESH:D012595 Scleroderma, Systemic Formaldehyde 9.2914979077
MESH:D012595 Scleroderma, Systemic Vinyl Chloride 9.2914979077
MESH:D012640 Seizures Ethanol 8.719754883
MESH:D012640 Seizures Isoniazid 8.7116107249
MESH:D012640 Seizures Phenobarbital 8.7111442880 3137016 16876388 4039156
MESH:D012640 Seizures Trinitrotoluene 8.7118551238
MESH:D003294 Seizures, Febrile Phenobarbital 3.916407741
MESH:D012729 Sex Chromosome Aberrations Chlorpyrifos 5.166418539
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.1718724381
MESH:D012851 Sinus Thrombosis, Intracranial Aspirin 4.3712269725
MESH:D012871 Skin Diseases Arsenic 4.446392382 19834688 16702368 17938729 18709164 17548696 15952646 17453740 17050553 16759981 16353154
MESH:D012871 Skin Diseases monomethylarsonic acid 4.4421378128
MESH:D012878 Skin Neoplasms Arsenic 22.6316251483 17029826 17050553 17976673 15504454 19538983
MESH:D012878 Skin Neoplasms cumene hydroperoxide 22.6312065085 8532709 17234724
MESH:D012878 Skin Neoplasms Fenretinide 22.6316467112
MESH:D012878 Skin Neoplasms N-(4-methoxyphenyl)retinamide 22.6316467112
MESH:D012878 Skin Neoplasms sodium arsenite 22.6318572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 22.638532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 22.6316192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 22.6318404319 8985016 12065085 11807781 8330346
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.4215464296
MESH:D013119 Spinal Cord Injuries Progesterone 3.3716503802 15862959
MESH:D016135 Spinal Dysraphism sodium arsenite 3.0512854658
MESH:D013163 Splenomegaly Trinitrotoluene 4.3115817613
MESH:D013272 Stomach Diseases Dexamethasone 11.9315472012
MESH:D013272 Stomach Diseases Indomethacin 11.9317160473 15038085 10215738 15472012 10486359 18209964 17207306 16113693 17638125 10192188 18545984 16280098 16184426
MESH:D013272 Stomach Diseases Omeprazole 11.9318545984
MESH:D013274 Stomach Neoplasms 1,3-butadiene 20.1811397402 2208121
MESH:D013274 Stomach Neoplasms 1,3-dichloro-1-propene 20.1811397402
MESH:D013274 Stomach Neoplasms arsenic trioxide 20.1817007042
MESH:D013274 Stomach Neoplasms Benzene 20.1812562636
MESH:D013274 Stomach Neoplasms Cisplatin 20.1818396642 15958060 17522103
MESH:D013274 Stomach Neoplasms Ethanol 20.1818456281
MESH:D013274 Stomach Neoplasms Ethylene Dibromide 20.183768853
MESH:D013274 Stomach Neoplasms Fluorouracil 20.1817172411 16951190 17522103 19015929 17498489 18567086 15786421 16424979 19084572 18396642
MESH:D013274 Stomach Neoplasms Indomethacin 20.1815609394
MESH:D013274 Stomach Neoplasms Paclitaxel 20.1818506536 18396642
MESH:D013274 Stomach Neoplasms styrene oxide 20.1812562636
MESH:D013274 Stomach Neoplasms troglitazone 20.1815930296
MESH:D013274 Stomach Neoplasms Vinyl Chloride 20.1812562636
MESH:D013276 Stomach Ulcer Amiodarone 17.6318087811
MESH:D013276 Stomach Ulcer Dexamethasone 17.6315138204
MESH:D013276 Stomach Ulcer Ethanol 17.6317189318 16755016 9562338 17918041 9211565 11906479
MESH:D013276 Stomach Ulcer Indomethacin 17.6316252198 14567935 11595415 16934674 15255614 12787963 12500499 18193104 17627676 17654042 10750652 18726076 16397915 18181030 16150113 18237397 17135157 18299717 10878458 11729361 15104355 11145282 18543354 12498302 17918041 11523592 18431645 18087811 16169175 11595431 10423059 18209962 12077510 12467913 1323529 17657623 15138204 17895592 16755016 17977527 16631530 11906479
MESH:D013276 Stomach Ulcer Omeprazole 17.6311906479 18237397 17977527 16755016 10750652 15991576
MESH:D013276 Stomach Ulcer Piroxicam 17.6315309881
MESH:D020521 Stroke Aspirin 3.6316403987
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.449754883
MESH:D013610 Tachycardia Amiodarone 3.4211238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 3.3219225199
MESH:D024801 Tauopathies Paclitaxel 3.9116930453
MESH:D013733 Testicular Diseases pyrazole 3.926499806
MESH:D013736 Testicular Neoplasms Cisplatin 3.7815464296 17225452
MESH:D013921 Thrombocytopenia 1-Naphthylisothiocyanate 3.9420133375
MESH:D013927 Thrombosis Aspirin 3.7317672075
MESH:D013953 Thymus Neoplasms Benzene 9.1810850423
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 9.1815790496
MESH:D013959 Thyroid Diseases Amiodarone 8.9819731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 8.9812697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 22.661399818 6582329 3712494 6587162 7505956
MESH:D013964 Thyroid Neoplasms arsenic trioxide 22.6619014326
MESH:D013964 Thyroid Neoplasms Butyrates 22.6617967635
MESH:D013964 Thyroid Neoplasms Indomethacin 22.6614736730 11352223 18791128
MESH:D013964 Thyroid Neoplasms Phenobarbital 22.661399818
MESH:D013964 Thyroid Neoplasms Propylthiouracil 22.6615710170
MESH:D013964 Thyroid Neoplasms triadimefon 22.6617178689
MESH:D013971 Thyrotoxicosis Amiodarone 3.9719584973 18020914
MESH:D013978 Tibial Fractures Estradiol 3.7619048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.1816280240
MESH:D016171 Torsades de Pointes Amiodarone 7.2617467628 11989578
MESH:D016171 Torsades de Pointes arsenic trioxide 7.2615213294
MESH:D014376 Tuberculosis Isoniazid 10.3115236969 16770646 17720495 15673755 17950035 18397238
MESH:D014376 Tuberculosis Pyrazinamide 10.3117373362 18397238
MESH:D014376 Tuberculosis Rifampin 10.3115236969 18397238
MESH:D014402 Tuberous Sclerosis Sirolimus 4.6921115397 18495876
MESH:D014456 Ulcer Indomethacin 3.9817380554 10574470
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 23.578074119
MESH:D001749 Urinary Bladder Neoplasms Arsenic 23.5715987713 17306315 17976673 18640142 11144890 19429237 19322015
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 23.5720435036 12845720 11780464 12973940
MESH:D001749 Urinary Bladder Neoplasms Cacodylic Acid 23.5715537745
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 23.5712973940 15464296 17225452
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 23.5716720286
MESH:D001749 Urinary Bladder Neoplasms Plant Preparations 23.5711251952
MESH:D001749 Urinary Bladder Neoplasms Quercetin 23.5716720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 23.5717306315 16712894 11723127 16452187
MESH:D014570 Urologic Diseases Diazinon 4.3516487989
MESH:D014581 Urticaria Acetaminophen 10.1410982225
MESH:D014581 Urticaria Aspirin 10.1410982225 20485159
MESH:D014581 Urticaria Piroxicam 10.1410982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 21.1716803524
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 21.1716154183
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 21.1716803524
MESH:D002583 Uterine Cervical Neoplasms indole-3-carbinol 21.1716082211
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 21.1711813266
MESH:D014594 Uterine Neoplasms Benzene 11.5112562636
MESH:D014594 Uterine Neoplasms Ethylene Oxide 11.5117325976 12562636
MESH:D014594 Uterine Neoplasms Sulindac 11.5118645019
MESH:D014605 Uveitis Cyclosporine 15.011336536
MESH:D014605 Uveitis Dexamethasone 15.011336536
MESH:D014605 Uveitis Sirolimus 15.011336536
MESH:D014625 Vaginal Neoplasms Cisplatin 3.7215577323
MESH:D014652 Vascular Diseases Arsenic 8.8317056641
MESH:D014652 Vascular Diseases sodium arsenite 8.8317056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.6712125929
MESH:D020301 Vasospasm, Intracranial Ibuprofen 4.2819057314
MESH:D014689 Venous Insufficiency coumarin 4.8512708602
MESH:D014839 Vomiting Cisplatin 8.4711897121
MESH:D014839 Vomiting Indomethacin 8.4711897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.3215886252
MESH:D014985 Xerophthalmia Cyclosporine 3.5117120751
Pathway ID Pathway Name
KEGG:00982 Drug metabolism - cytochrome P450
KEGG:00480 Glutathione metabolism
KEGG:00980 Metabolism of xenobiotics by cytochrome P450
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA183
    • Releated gene ID Related gene Name
    PA183GSTT1
    Releated disease ID Related disease Name
    PA443624Carcinoma, Renal Cell
    PA443937Drug Toxicity
    PA444320Graft vs Host Disease
    PA134850491Transplantation
    PA445018Cardiomyopathies
    PA443797Coronary Disease
    PA445062Neoplasms
    PA445742Stomach Neoplasms
    PA443560Breast Neoplasms
    PA444552Hypertension
    PA446108Colorectal Neoplasms
    PA444760Leukemia, Myeloid, Acute
    PA446357Neoplasms, Second Primary
    PA444704Premature Birth
    PA444065Epilepsy
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    PA444818Lung Neoplasms
    PA443485Basal Cell Nevus Syndrome
    PA444355Hearing Disorders
    PA443890Diabetes Mellitus, Type 2
    PA443899Diarrhea
    PA445113Neutropenia
    PA444257Gastrointestinal Neoplasms
    PA445301Peripheral Nervous System Diseases
    PA446975Neurotoxicity Syndromes
    PA446411Endometrial Neoplasms
    PA445425Prostatic Neoplasms
    PA443512Urinary Bladder Neoplasms
    PA443319Alzheimer Disease
    PA443224Abnormalities, Drug-Induced
    PA164925725Toxic liver disease
    Releated drug ID Related drug Name
    PA164749376interferon alfacon-1
    PA449167cyclosporine
    PA449247dexamethasone
    PA450198leucovorin
    PA449412doxorubicin
    PA451668thiotepa
    PA130620651anthracyclines and related substances
    PA451283rosiglitazone
    PA131285527oxaliplatin
    PA449014cisplatin
    PA449165cyclophosphamide
    PA128406956fluorouracil
    PA452604xenobiotics
    PA451611teniposide
    PA450354melphalan
    PA448785carbamazepine
    PA448492asparaginase
    PA449177cytarabine
    PA449212daunorubicin
    PA449552etoposide
    PA450379mercaptopurine
    PA450428methotrexate
    PA451100prednisone
    PA451879vincristine
    PA452621antineoplastic agents
    PA448691busulfan
    PA448771capecitabine
    PA450085irinotecan
    PA164713176Platinum compounds
    PA451576tacrine
    PA448406amoxicillin
    PA164712405Antibacterials For Systemic Use
    PA164712462Antiinflammatory agents, non-steroids
    PA164742987clavulanate
    PA164712471Antimycobacterials
    PA164712708Drugs For Treatment Of Tuberculosis
    PA450112isoniazid
    PA451799troglitazone
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00143 - BSS Plus Dietary supplement;Micronutrient
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved