AutismKB 2.0

Annotation Detail for NCAPH2


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Basic Information Top
Gene Symbol:NCAPH2 ( CAPH2,MGC15858,MGC18000,MGC2455,MGC4133,MGC5305,MGC8640 )
Gene Full Name: non-SMC condensin II complex, subunit H2
Band: 22q13.33
Quick LinksEntrez ID:29781; OMIM: 611230; Uniprot ID:CNDH2_HUMAN; ENSEMBL ID: ENSG00000025770; HGNC ID: 25071
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of NCAPH2 mRNAaffects expression 17562736
D003345 Corticosterone Corticosterone results in decreased expression of NCAPH2 mRNAdecreases expression 15755911
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of NCAPH2 mRNAdecreases expression 17108234
D005038 Ethylnitrosourea Ethylnitrosourea results in increased mutagenesis of NCAPH2 geneincreases mutagenesis 17640884
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.6617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8814692618
MESH:D000236 Adenoma Ethylnitrosourea 3.926695378
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.0211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8915885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001927 Brain Diseases Ethylnitrosourea 5.2814991843
MESH:D001932 Brain Neoplasms Ethylnitrosourea 4.6816357521 18412241 16436596 15144691 16651633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 3.9816003739
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 6.7117160924
MESH:D002779 Cholestasis Ethinyl Estradiol 3.1715861022 16919318 17333356 16105132 17110522 17681005 11677210
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6719739265 12392966 11287661 19420014 18071297 19923254 10915739 14986274 11461765 14550746 16109766 12153990 14725611 17562736 16781746 19164858 12705907 16177239 19416960 18713872 15968718 16393943 17906064 11743745 11421492 10663392 17522070 16227642 16081117 12958197 19085960 2444490 10774834 11739529 15619225 11529661 12540782 11834606 19370779 12594235 16485898
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 6.7118357618
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.6912538720
MESH:D005234 Fatty Liver Ethinyl Estradiol 3.2415345470
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D005909 Glioblastoma Ethylnitrosourea 4.0716436596
MESH:D005910 Glioma Ethylnitrosourea 3.6216651633 18412241 16357521
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D007021 Hypospadias Ethinyl Estradiol 4.3716569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7317937319
MESH:D007674 Kidney Diseases Acetaminophen 2.4012587719 15629191
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 4.2717379185
MESH:D008107 Liver Diseases Acetaminophen 1.7016611625 12587719 12969438 11587558 16610002 19784758 19014921 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6316871587 17185352
MESH:D008175 Lung Neoplasms Ethylnitrosourea 2.6316019985 17703301 16271038 6695378
MESH:D008223 Lymphoma Ethylnitrosourea 4.2215790496
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 5.6115375218
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 7.4912807724
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 7.4918041768 10767621 10838139
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D008579 Meningioma Ethylnitrosourea 6.7117943659
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 4.9616707424
MESH:D009442 Neurilemmoma Ethylnitrosourea 6.0517160924 16651423 16003739
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D009837 Oligodendroglioma Ethylnitrosourea 6.7117160924
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.1511578682
MESH:D011537 Pruritus Ethinyl Estradiol 3.9416919318 15861022
MESH:D013088 Spermatocele Ethinyl Estradiol 4.6616709447
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5215669648
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 5.7915790496
MESH:D014581 Urticaria Acetaminophen 3.4410982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8014692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9714671159 15869587
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018