Annotation Detail for GUCA2A
Basic Information Top
| Gene Symbol: | GUCA2A ( GUANYLIN,GUCA2,STARA ) |
|---|---|
| Gene Full Name: | guanylate cyclase activator 2A (guanylin) |
| Band: | 1p34.2 |
| Quick Links | Entrez ID:2980; OMIM: 139392; Uniprot ID:GUC2A_HUMAN; ENSEMBL ID: ENSG00000197273; HGNC ID: 4682 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of GUCA2A mRNA | affects expression | 16483693 |
| D004041 | Dietary Fats | Dietary Fats results in decreased expression of GUCA2A mRNA | decreases expression | 18457598 |
| C029424 | hydrazine | hydrazine results in decreased expression of GUCA2A mRNA | decreases expression | 15282401 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000138 | Acidosis | Ammonium Chloride | 4.30 | 18287403 | |
| MESH:D001161 | Arteriosclerosis | Dietary Fats | 4.54 | 15238619 | |
| MESH:D001943 | Breast Neoplasms | Dietary Fats | 2.24 | 20435547 | |
| MESH:D050171 | Dyslipidemias | Dietary Fats | 3.76 | 18367378 | |
| MESH:D005234 | Fatty Liver | Dietary Fats | 3.72 | 17967931 19551842 18296743 19004024 | |
| MESH:D005355 | Fibrosis | Dietary Fats | 4.17 | 18296743 | |
| MESH:D006937 | Hypercholesterolemia | Dietary Fats | 4.08 | 21332399 | |
| MESH:D006949 | Hyperlipidemias | Dietary Fats | 4.14 | 21332399 | |
| MESH:D007249 | Inflammation | Dietary Fats | 2.62 | 20412841 | |
| MESH:D007333 | Insulin Resistance | Dietary Fats | 3.37 | 18457598 11836018 | |
| MESH:D008103 | Liver Cirrhosis | Dietary Fats | 3.09 | 18296743 | |
| MESH:D009765 | Obesity | Dietary Fats | 2.36 | 20518802 21332399 11836018 17217161 16723640 18457598 18674790 19632207 20132043 | |
| MESH:D015430 | Weight Gain | Dietary Fats | 4.15 | 16723640 |
| No data |