AutismKB 2.0

Annotation Detail for ZDHHC8


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Basic Information Top
Gene Symbol:ZDHHC8 ( DHHC8,ZDHHCL1,ZNF378 )
Gene Full Name: zinc finger, DHHC-type containing 8
Band: 22q11.21
Quick LinksEntrez ID:29801; OMIM: 608784; Uniprot ID:ZDHC8_HUMAN; ENSEMBL ID: ENSG00000099904; HGNC ID: 18474
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2069Schizophrenia
Desease Name
PSYCH
schizophrenia
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of ZDHHC8 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 5.2610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8610977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.692444490 10915739 16781746 10663392 12392966 18071297 16177239 12540782 11421492 11743745 14725611 11739529 17522070 17906064 19420014 12153990 15619225 18713872 19370779 14550746 19085960 11287661 12958197 11529661 10774834 19923254 17562736 16393943 16081117 12705907 19416960 14986274 11461765 12594235 16485898 16109766 16227642 19739265 15968718 11834606 19164858
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.5119426721
MESH:D005756 Gastritis Acetaminophen 5.0916983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1516870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4715629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7219784758 16611625 16610002 19460945 11587558 19014921 12969438 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.8117185352 16871587
MESH:D008546 Melanoma, Experimental Acetaminophen 4.4719513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3618514411
MESH:D010146 Pain Acetaminophen 2.8716870215
MESH:D014581 Urticaria Acetaminophen 3.6710982225
No data
Pharmacogenomics Knowledge Base Top
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018