Annotation Detail for GUCY1A3
Basic Information Top
| Gene Symbol: | GUCY1A3 ( GC-SA3,GUC1A3,GUCA3,GUCSA3,GUCY1A1 ) |
|---|---|
| Gene Full Name: | guanylate cyclase 1, soluble, alpha 3 |
| Band: | 4q32.1 |
| Quick Links | Entrez ID:2982; OMIM: 139396; Uniprot ID:GCYA3_HUMAN; ENSEMBL ID: ENSG00000164116; HGNC ID: 4685 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C095284 | 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one | 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one affects the folding of [Nitric Oxide binds to [GUCY1A3 protein binds to GUCY1B3 protein]] | affects binding|affects folding | 11744065 |
| C095284 | 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one | 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [3-(2-(2,2-dimethylpropylsulfanyl)pyridin-3-yl)-N-(3-hydroxycyclohexyl)acrylamide results in increased activity of [GUCY1A3 protein binds to GUCY1B3 protein]] | affects binding|decreases reaction|increases activity | 17050951 |
| C095284 | 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one | 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [3-(2-(4-chlorophenylsulfanyl)phenyl)-N-(4-dimethylaminobutyl)acrylamide results in increased activity of [GUCY1A3 protein binds to GUCY1B3 protein]] | affects binding|decreases reaction|increases activity | 12495780 |
| C095284 | 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one | 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [Nitroprusside results in increased activity of [GUCY1A3 protein binds to GUCY1B3 protein]] | affects binding|decreases reaction|increases activity | 12495780 |
| C023514 | 2,6-dinitrotoluene | 2,6-dinitrotoluene results in increased expression of GUCY1A3 mRNA | increases expression | 20406850 |
| C023514 | 2,6-dinitrotoluene | 2,6-dinitrotoluene affects the expression of GUCY1A3 mRNA | affects expression | 21346803 |
| C515661 | 3-(2-(2,2-dimethylpropylsulfanyl)pyridin-3-yl)-N-(3-hydroxycyclohexyl)acrylamide | 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [3-(2-(2,2-dimethylpropylsulfanyl)pyridin-3-yl)-N-(3-hydroxycyclohexyl)acrylamide results in increased activity of [GUCY1A3 protein binds to GUCY1B3 protein]] | affects binding|decreases reaction|increases activity | 17050951 |
| C515661 | 3-(2-(2,2-dimethylpropylsulfanyl)pyridin-3-yl)-N-(3-hydroxycyclohexyl)acrylamide | 3-(2-(2,2-dimethylpropylsulfanyl)pyridin-3-yl)-N-(3-hydroxycyclohexyl)acrylamide results in increased activity of [GUCY1A3 protein binds to GUCY1B3 protein] | affects binding|increases activity | 17050951 |
| C515661 | 3-(2-(2,2-dimethylpropylsulfanyl)pyridin-3-yl)-N-(3-hydroxycyclohexyl)acrylamide | Nitroprusside promotes the reaction [3-(2-(2,2-dimethylpropylsulfanyl)pyridin-3-yl)-N-(3-hydroxycyclohexyl)acrylamide results in increased activity of [GUCY1A3 protein binds to GUCY1B3 protein]] | affects binding|increases activity|increases reaction | 17050951 |
| C470768 | 3-(2-(4-chlorophenylsulfanyl)phenyl)-N-(4-dimethylaminobutyl)acrylamide | 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [3-(2-(4-chlorophenylsulfanyl)phenyl)-N-(4-dimethylaminobutyl)acrylamide results in increased activity of [GUCY1A3 protein binds to GUCY1B3 protein]] | affects binding|decreases reaction|increases activity | 12495780 |
| C470768 | 3-(2-(4-chlorophenylsulfanyl)phenyl)-N-(4-dimethylaminobutyl)acrylamide | 3-(2-(4-chlorophenylsulfanyl)phenyl)-N-(4-dimethylaminobutyl)acrylamide promotes the reaction [Nitroprusside results in increased activity of [GUCY1A3 protein binds to GUCY1B3 protein]] | affects binding|increases activity|increases reaction | 12495780 |
| C470768 | 3-(2-(4-chlorophenylsulfanyl)phenyl)-N-(4-dimethylaminobutyl)acrylamide | 3-(2-(4-chlorophenylsulfanyl)phenyl)-N-(4-dimethylaminobutyl)acrylamide results in increased activity of [GUCY1A3 protein binds to GUCY1B3 protein] | affects binding|increases activity | 12495780 |
| C090937 | 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole | 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole affects the folding of [Nitric Oxide binds to [GUCY1A3 protein binds to GUCY1B3 protein]] | affects binding|affects folding | 11744065 |
| C090937 | 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole | 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole promotes the reaction [Nitroprusside results in increased activity of [GUCY1A3 protein binds to GUCY1B3 protein]] | affects binding|increases activity|increases reaction | 12495780 |
| C090937 | 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole | 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in increased activity of [GUCY1A3 protein binds to GUCY1B3 protein] | affects binding|increases activity | 12495780 |
| D000643 | Ammonium Chloride | Ammonium Chloride results in decreased expression of GUCY1A3 protein | decreases expression | 16517024 |
| D016572 | Cyclosporine | Cyclosporine results in decreased expression of GUCY1A3 mRNA | decreases expression | 20106945 |
| D004958 | Estradiol | Estradiol deficiency results in decreased expression of GUCY1A3 mRNA | decreases expression | 18787021 |
| D004958 | Estradiol | Estradiol deficiency results in decreased expression of GUCY1A3 protein | decreases expression | 18787021 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in decreased expression of GUCY1A3 mRNA | decreases expression | 17557909 15834898 12655037 17351261 |
| D007529 | Isoflavones | Isoflavones results in decreased expression of GUCY1A3 mRNA | decreases expression | 19025659 |
| D008070 | Lipopolysaccharides | ESR1 protein affects the reaction [Lipopolysaccharides affects the expression of GUCY1A3 mRNA] | affects expression|affects reaction | 17158209 |
| D008070 | Lipopolysaccharides | ESR1 protein affects the reaction [Lipopolysaccharides affects the expression of GUCY1A3 protein] | affects expression|affects reaction | 17158209 |
| C008493 | methylselenic acid | AR protein inhibits the reaction [methylselenic acid results in decreased expression of GUCY1A3 mRNA] | decreases expression|decreases reaction | 16020662 |
| C008493 | methylselenic acid | methylselenic acid affects the expression of GUCY1A3 mRNA | affects expression | 14617803 |
| C008493 | methylselenic acid | methylselenic acid results in decreased expression of GUCY1A3 mRNA | decreases expression | 16020662 18548127 |
| D009569 | Nitric Oxide | 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one affects the folding of [Nitric Oxide binds to [GUCY1A3 protein binds to GUCY1B3 protein]] | affects binding|affects folding | 11744065 |
| D009569 | Nitric Oxide | 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole affects the folding of [Nitric Oxide binds to [GUCY1A3 protein binds to GUCY1B3 protein]] | affects binding|affects folding | 11744065 |
| D005996 | Nitroglycerin | Nitroglycerin results in increased expression of GUCY1A3 mRNA | increases expression | 11331261 |
| D005996 | Nitroglycerin | Nitroglycerin results in increased expression of GUCY1A3 protein | increases expression | 11331261 |
| D009599 | Nitroprusside | 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [Nitroprusside results in increased activity of [GUCY1A3 protein binds to GUCY1B3 protein]] | affects binding|decreases reaction|increases activity | 12495780 |
| D009599 | Nitroprusside | 3-(2-(4-chlorophenylsulfanyl)phenyl)-N-(4-dimethylaminobutyl)acrylamide promotes the reaction [Nitroprusside results in increased activity of [GUCY1A3 protein binds to GUCY1B3 protein]] | affects binding|increases activity|increases reaction | 12495780 |
| D009599 | Nitroprusside | 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole promotes the reaction [Nitroprusside results in increased activity of [GUCY1A3 protein binds to GUCY1B3 protein]] | affects binding|increases activity|increases reaction | 12495780 |
| D009599 | Nitroprusside | Nitroprusside promotes the reaction [3-(2-(2,2-dimethylpropylsulfanyl)pyridin-3-yl)-N-(3-hydroxycyclohexyl)acrylamide results in increased activity of [GUCY1A3 protein binds to GUCY1B3 protein]] | affects binding|increases activity|increases reaction | 17050951 |
| D009599 | Nitroprusside | Nitroprusside results in increased activity of [GUCY1A3 protein binds to GUCY1B3 protein] | affects binding|increases activity | 12495780 17050951 |
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of GUCY1A3 mRNA | affects binding|decreases expression|increases activity | 19710929 |
| D018038 | Sodium Selenite | Sodium Selenite results in decreased expression of GUCY1A3 mRNA | decreases expression | 18175754 |
| D013654 | Taurine | Taurine results in decreased expression of GUCY1A3 mRNA | decreases expression | 16579726 |
| D014415 | Tunicamycin | Tunicamycin results in increased expression of GUCY1A3 mRNA | increases expression | 17127020 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000138 | Acidosis | Ammonium Chloride | 3.50 | 18287403 | |
| MESH:D000152 | Acne Vulgaris | Ethinyl Estradiol | 3.89 | 17505938 | |
| MESH:D055371 | Acute Lung Injury | Lipopolysaccharides | 8.83 | 18653653 11850527 | |
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 8.83 | 18653653 | |
| MESH:D000230 | Adenocarcinoma | Estradiol | 4.16 | 11473722 | |
| MESH:D000230 | Adenocarcinoma | Ethinyl Estradiol | 4.16 | 14692618 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 3.42 | 16434500 | |
| MESH:D000505 | Alopecia | Isoflavones | 4.66 | 17569567 | |
| MESH:D000544 | Alzheimer Disease | Nitric Oxide | 3.30 | 17556102 | |
| MESH:D001161 | Arteriosclerosis | Ethinyl Estradiol | 3.40 | 11256880 | |
| MESH:D001169 | Arthritis, Experimental | Ethinyl Estradiol | 2.62 | 15885639 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 3.08 | 19483382 | |
| MESH:D001930 | Brain Injuries | Nitroprusside | 5.63 | 14637104 | |
| MESH:D001943 | Breast Neoplasms | Estradiol | 2.59 | 16675129 17261762 12948864 17018787 17289903 14630087 19861407 18497071 | |
| MESH:D001943 | Breast Neoplasms | Nitric Oxide | 2.59 | 15631943 | |
| MESH:D002181 | Candidiasis, Vulvovaginal | Estradiol | 4.40 | 16111702 | |
| MESH:D003528 | Carcinoma, Adenoid Cystic | marker/mechanism | 16762588 | ||
| MESH:D006528 | Carcinoma, Hepatocellular | 2,6-dinitrotoluene | 2.93 | 16705839 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Estradiol | 2.93 | 16924424 | |
| MESH:D002318 | Cardiovascular Diseases | Isoflavones | 4.10 | 17689850 | |
| MESH:D002471 | Cell Transformation, Neoplastic | 2,6-dinitrotoluene | 10.87 | 6135515 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Cyclosporine | 10.87 | 12371664 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Estradiol | 10.87 | 18566989 | |
| MESH:D002779 | Cholestasis | Cyclosporine | 18.87 | 19486331 | |
| MESH:D002779 | Cholestasis | Ethinyl Estradiol | 18.87 | 17681005 17110522 16919318 15861022 16105132 11677210 17333356 | |
| MESH:D002779 | Cholestasis | Nitric Oxide | 18.87 | 16919318 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 18.87 | 19176532 | |
| MESH:D019457 | Chromosome Breakage | Sodium Selenite | 4.69 | 15894690 | |
| MESH:D015179 | Colorectal Neoplasms | Isoflavones | 2.90 | 17116718 | |
| MESH:D003490 | Cyanosis | 2,6-dinitrotoluene | 3.95 | 18551238 | |
| MESH:D015140 | Dementia, Vascular | Nitric Oxide | 5.90 | 17556102 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.39 | 18249437 | |
| MESH:D003920 | Diabetes Mellitus | Sodium Selenite | 3.72 | 16285004 | |
| MESH:D058065 | Diabetic Cardiomyopathies | Taurine | 5.99 | 16025228 | |
| MESH:D003928 | Diabetic Nephropathies | Estradiol | 3.35 | 19279558 | |
| MESH:D056486 | Drug-Induced Liver Injury | 2,6-dinitrotoluene | 6.37 | 18551238 21346803 | |
| MESH:D056486 | Drug-Induced Liver Injury | Sodium Selenite | 6.37 | 15131321 | |
| MESH:D056486 | Drug-Induced Liver Injury | Taurine | 6.37 | 9328219 | |
| MESH:D004487 | Edema | pirinixic acid | 2.42 | 12083418 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Ethinyl Estradiol | 3.12 | 12538720 | |
| MESH:D016889 | Endometrial Neoplasms | Estradiol | 2.94 | 11473722 19148513 18566989 | |
| MESH:D019446 | Endotoxemia | Lipopolysaccharides | 4.33 | 15821434 17637181 15328337 | |
| MESH:D007172 | Erectile Dysfunction | 3-(2-(2,2-dimethylpropylsulfanyl)pyridin-3-yl)-N-(3-hydroxycyclohexyl)acrylamide | 11.77 | 17050951 | |
| MESH:D007172 | Erectile Dysfunction | 3-(2-(4-chlorophenylsulfanyl)phenyl)-N-(4-dimethylaminobutyl)acrylamide | 11.77 | 12495780 | |
| MESH:D005234 | Fatty Liver | Cyclosporine | 12.64 | 19224547 | |
| MESH:D005234 | Fatty Liver | Ethinyl Estradiol | 12.64 | 15345470 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 12.64 | 20131406 19236843 | |
| MESH:D005334 | Fever | Lipopolysaccharides | 3.95 | 9205823 11852909 | |
| MESH:D005355 | Fibrosis | Cyclosporine | 3.08 | 12168785 12639820 | |
| MESH:D005885 | Gingival Hyperplasia | Cyclosporine | 4.16 | 8708960 | |
| MESH:D006261 | Headache | Nitric Oxide | 11.19 | 11284996 11554966 | |
| MESH:D006261 | Headache | Nitroglycerin | 11.19 | 11554966 11284996 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 2.50 | 20558911 | |
| MESH:D006457 | Hemoglobinuria, Paroxysmal | Cyclosporine | 4.36 | 15720958 | |
| MESH:D006463 | Hemolytic-Uremic Syndrome | Lipopolysaccharides | 4.32 | 16366002 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 2.93 | 16221962 19772884 19176532 18467677 | |
| MESH:D006558 | Herpes Genitalis | Estradiol | 4.98 | 15709030 | |
| MESH:D019584 | Hot Flashes | Estradiol | 10.23 | 17088409 | |
| MESH:D019584 | Hot Flashes | Isoflavones | 10.23 | 14716179 17290160 | |
| MESH:D006940 | Hyperemia | Nitric Oxide | 5.55 | 11156591 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 3.12 | 20558911 | |
| MESH:D006973 | Hypertension | Cyclosporine | 2.07 | 10903974 | |
| MESH:D006976 | Hypertension, Pulmonary | Nitric Oxide | 4.37 | 15838368 | |
| MESH:D007021 | Hypospadias | Ethinyl Estradiol | 3.75 | 16569931 16945680 | |
| MESH:D007247 | Infertility, Female | Ethinyl Estradiol | 3.40 | 12013081 | |
| MESH:D007248 | Infertility, Male | Ethinyl Estradiol | 2.44 | 17937319 | |
| MESH:D007249 | Inflammation | Lipopolysaccharides | 2.84 | 12878042 9205823 17237260 17255318 17963957 | |
| MESH:D007333 | Insulin Resistance | Estradiol | 12.06 | 16627594 16393666 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 12.06 | 16306350 | |
| MESH:D007333 | Insulin Resistance | Sodium Selenite | 12.06 | 14714311 | |
| MESH:D007410 | Intestinal Diseases | Nitric Oxide | 4.87 | 11713966 10210152 11574821 | |
| MESH:D019189 | Iron Metabolism Disorders | Lipopolysaccharides | 4.57 | 17255318 | |
| MESH:D007638 | Keratoconjunctivitis Sicca | Cyclosporine | 4.39 | 15604871 | |
| MESH:D007674 | Kidney Diseases | Cyclosporine | 5.81 | 18776723 10903974 8314463 | |
| MESH:D007674 | Kidney Diseases | Estradiol | 5.81 | 15618244 | |
| MESH:D007680 | Kidney Neoplasms | 2,6-dinitrotoluene | 12.04 | 16705839 | |
| MESH:D007680 | Kidney Neoplasms | Cyclosporine | 12.04 | 12371664 | |
| MESH:D007680 | Kidney Neoplasms | Estradiol | 12.04 | 15610895 | |
| MESH:D007896 | Leishmaniasis | Nitric Oxide | 4.60 | 17218153 | |
| MESH:D007970 | Leukopenia | Lipopolysaccharides | 4.64 | 15821434 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Estradiol | 4.98 | 14659978 14716833 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Lipopolysaccharides | 4.98 | 12878042 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 4.98 | 15474484 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Taurine | 4.98 | 15931870 15893842 | |
| MESH:D008113 | Liver Neoplasms | 2,6-dinitrotoluene | 4.33 | 7678174 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 4.33 | 15890375 20007298 16377806 | |
| MESH:D008114 | Liver Neoplasms, Experimental | 2,6-dinitrotoluene | 2.50 | 2876786 2876784 6135515 | |
| MESH:D055370 | Lung Injury | Lipopolysaccharides | 9.35 | 21114838 | |
| MESH:D055370 | Lung Injury | Nitric Oxide | 9.35 | 11395602 | |
| MESH:D008223 | Lymphoma | Nitric Oxide | 4.23 | 16166326 | |
| MESH:D016393 | Lymphoma, B-Cell | Sodium Selenite | 4.00 | 14737004 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Estradiol | 2.52 | 11408345 11807958 17203775 16891317 | |
| MESH:D020149 | Manganese Poisoning | Estradiol | 4.43 | 19453300 | |
| MESH:D008664 | Metal Metabolism, Inborn Errors | Cyclosporine | 4.73 | 16801185 | |
| MESH:D008708 | Methemoglobinemia | Nitroglycerin | 4.67 | 3537620 | |
| MESH:D008881 | Migraine Disorders | Nitric Oxide | 4.23 | 11701602 | |
| MESH:D020326 | Migraine without Aura | Nitric Oxide | 10.94 | 11304026 14659530 | |
| MESH:D020326 | Migraine without Aura | Nitroglycerin | 10.94 | 14659530 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 3.44 | 16239165 | |
| MESH:D009203 | Myocardial Infarction | Nitroglycerin | 5.93 | 14729435 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 5.93 | 19151258 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Estradiol | 8.08 | 16810080 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 8.08 | 16411023 | |
| MESH:D009336 | Necrosis | 2,6-dinitrotoluene | 3.80 | 18551238 7678174 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 1.92 | 17405874 | |
| MESH:D009389 | Neovascularization, Pathologic | Estradiol | 3.67 | 17289903 | |
| MESH:D009402 | Nephrosis, Lipoid | Cyclosporine | 4.39 | 17954296 | |
| MESH:D009404 | Nephrotic Syndrome | Cyclosporine | 3.23 | 19348381 18481113 | |
| MESH:D009421 | Nervous System Malformations | Estradiol | 3.59 | 11399458 16427766 | |
| MESH:D009765 | Obesity | pirinixic acid | 1.80 | 20558911 | |
| MESH:D009784 | Occupational Diseases | 2,6-dinitrotoluene | 3.37 | 16049721 | |
| MESH:D010024 | Osteoporosis | Isoflavones | 4.06 | 16562857 | |
| MESH:D010051 | Ovarian Neoplasms | Estradiol | 2.20 | 19401270 | |
| MESH:D016584 | Panic Disorder | Ethinyl Estradiol | 3.62 | 11578682 | |
| MESH:D011014 | Pneumonia | Lipopolysaccharides | 4.49 | 11605937 12224865 | |
| MESH:D011015 | Pneumonia, Aspiration | Nitric Oxide | 5.27 | 18573544 | |
| MESH:D011230 | Precancerous Conditions | Cyclosporine | 3.16 | 12371664 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | Estradiol | 3.82 | 20887781 | |
| MESH:D011471 | Prostatic Neoplasms | Estradiol | 2.17 | 16740699 | |
| MESH:D011471 | Prostatic Neoplasms | Isoflavones | 2.17 | 17219775 17571952 16365062 17374662 | |
| MESH:D011471 | Prostatic Neoplasms | methylselenic acid | 2.17 | 16205645 | |
| MESH:D011471 | Prostatic Neoplasms | Sodium Selenite | 2.17 | 18760546 | |
| MESH:D011537 | Pruritus | Ethinyl Estradiol | 3.25 | 15861022 16919318 | |
| MESH:D011565 | Psoriasis | Cyclosporine | 2.21 | 16882103 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.35 | 19058328 | |
| MESH:D012130 | Respiratory Hypersensitivity | Lipopolysaccharides | 3.69 | 10835634 | |
| MESH:D012468 | Salivary Gland Neoplasms | marker/mechanism | 16762588 | ||
| MESH:D012555 | Schistosomiasis mansoni | Nitric Oxide | 5.37 | 9673227 | |
| MESH:D012640 | Seizures | 2,6-dinitrotoluene | 2.49 | 18551238 | |
| MESH:D013088 | Spermatocele | Ethinyl Estradiol | 3.89 | 16709447 | |
| MESH:D013276 | Stomach Ulcer | Nitric Oxide | 4.13 | 15138204 | |
| MESH:D013610 | Tachycardia | Nitroprusside | 5.55 | 15306635 | |
| MESH:D013921 | Thrombocytopenia | Lipopolysaccharides | 4.10 | 15821434 | |
| MESH:D019851 | Thrombophilia | Ethinyl Estradiol | 3.56 | 11994571 | |
| MESH:D013927 | Thrombosis | Ethinyl Estradiol | 3.09 | 15669648 | |
| MESH:D013978 | Tibial Fractures | Estradiol | 4.63 | 19048282 | |
| MESH:D001749 | Urinary Bladder Neoplasms | 2,6-dinitrotoluene | 2.26 | 16049721 | |
| MESH:D014571 | Urologic Neoplasms | 2,6-dinitrotoluene | 4.26 | 10091137 | |
| MESH:D014594 | Uterine Neoplasms | Ethinyl Estradiol | 3.23 | 14692618 | |
| MESH:D014605 | Uveitis | Cyclosporine | 3.93 | 1336536 | |
| MESH:D020246 | Venous Thrombosis | Ethinyl Estradiol | 3.48 | 15869587 14671159 | |
| MESH:D014985 | Xerophthalmia | Cyclosporine | 4.39 | 17120751 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:04540 | Gap junction |
| REACT:604 | Hemostasis |
| KEGG:04730 | Long-term depression |
| KEGG:00230 | Purine metabolism |
| KEGG:04970 | Salivary secretion |
| KEGG:04270 | Vascular smooth muscle contraction |