AutismKB 2.0

Annotation Detail for UBN1


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Basic Information Top
Gene Symbol:UBN1 ( VT,VT4 )
Gene Full Name: ubinuclein 1
Band: 16p13.3
Quick LinksEntrez ID:29855; OMIM: 609771; Uniprot ID:UBN1_HUMAN; ENSEMBL ID: ENSG00000118900; HGNC ID: 12506
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of UBN1 mRNAaffects expression 17562736
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in increased expression of UBN1 mRNAincreases expression 16934159
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of UBN1 mRNAdecreases expression 17555576
D010656 Phenylephrine Phenylephrine results in decreased expression of UBN1 mRNAdecreases expression 18158353
D012402 Rotenone Rotenone results in increased expression of UBN1 mRNAincreases expression 19013527
D012643 Selenium [Selenium co-treated with Vitamin E] results in decreased expression of UBN1 mRNAaffects cotreatment|decreases expression 19244175
D012643 Selenium [Selenium co-treated with Vitamin E] results in increased expression of UBN1 mRNAaffects cotreatment|increases expression 19244175
D012643 Selenium Selenium results in decreased expression of UBN1 mRNAdecreases expression 19244175
D012643 Selenium Selenium results in increased expression of UBN1 mRNAincreases expression 19244175
C004648 testosterone enanthate testosterone enanthate affects the expression of UBN1 mRNAaffects expression 17440010
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in decreased expression of UBN1 mRNAaffects cotreatment|decreases expression 19244175
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in increased expression of UBN1 mRNAaffects cotreatment|increases expression 19244175
D014810 Vitamin E Vitamin E results in decreased expression of UBN1 mRNAdecreases expression 19244175
D014810 Vitamin E Vitamin E results in increased expression of UBN1 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.3217505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8614692618
MESH:D000799 Angioedema Acetaminophen 4.2210982225
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 4.3417460149
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.7711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8015885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001919 Bradycardia Phenylephrine 4.8815306635
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.2416050911
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.393084413
MESH:D006332 Cardiomegaly Phenylephrine 3.6511179087 17287366 15728586 16170337 11754973 17124262
MESH:D002386 Cataract Acetaminophen 2.7110977129
MESH:D002779 Cholestasis Ethinyl Estradiol 3.0517110522 16105132 15861022 11677210 17681005 17333356 16919318
MESH:D003092 Colitis Selenium 4.0917936198
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.692444490 12540782 16109766 19739265 19420014 11739529 14986274 12153990 19370779 14550746 16393943 10663392 11287661 14725611 16081117 18713872 19416960 16781746 15619225 11529661 18071297 11461765 17562736 16227642 11834606 17906064 15968718 16485898 19085960 16177239 12392966 12594235 11743745 11421492 17522070 19164858 19923254 12705907 10774834 12958197 10915739
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 6.6917851650
MESH:D056486 Drug-Induced Liver Injury Selenium 6.6915131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.4719426721
MESH:C538011 Eales disease Vitamin E 5.089068938
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.4712538720
MESH:D005234 Fatty Liver Ethinyl Estradiol 3.0515345470
MESH:D005756 Gastritis Acetaminophen 4.0516983495
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1016080930
MESH:D006333 Heart Failure Selenium 3.2117162251
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7716863852 16490937
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 6.1217440010
MESH:D019584 Hot Flashes Vitamin E 4.3514716179
MESH:D006930 Hyperalgesia Acetaminophen 2.8916870215
MESH:D006973 Hypertension Phenylephrine 3.1512717712 8949925
MESH:D006984 Hypertrophy Phenylephrine 4.8018502941 12791704
MESH:D007021 Hypospadias Ethinyl Estradiol 4.1216945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.7212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.6417937319
MESH:D007251 Influenza, Human Selenium 12.2516624496
MESH:D007251 Influenza, Human Vitamin E 12.2516624496
MESH:D007674 Kidney Diseases Acetaminophen 6.3915629191 12587719
MESH:D007674 Kidney Diseases Vitamin E 6.3912488133
MESH:D007676 Kidney Failure, Chronic Selenium 4.1316518626
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9016169303
MESH:D008107 Liver Diseases Acetaminophen 1.6712587719 19014921 11587558 16611625 16610002 12969438 19460945 19784758
MESH:D017114 Liver Failure, Acute Acetaminophen 3.4616871587 17185352
MESH:D008171 Lung Diseases Vitamin E 3.3316863852
MESH:D008175 Lung Neoplasms Vitamin E 1.9011062179
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.9015318939
MESH:D008546 Melanoma, Experimental Acetaminophen 3.8719513568
MESH:D008654 Mesothelioma Selenium 2.8715107826
MESH:D009410 Nerve Degeneration Rotenone 4.0617356569 18619942 15790535
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.0718514411
MESH:D010146 Pain Acetaminophen 2.5916870215
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.9511578682
MESH:D010300 Parkinson Disease Rotenone 3.0511535288 18191903 18619942 15451049 19232380 19114014 16412576 11445065 16140633
MESH:D020734 Parkinsonian Disorders Rotenone 4.3015927086 15574749 15795934 18197244
MESH:D010954 Plasmacytoma Selenium 5.2715087411
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2615084515
MESH:D011537 Pruritus Ethinyl Estradiol 3.6515861022 16919318
MESH:D012852 Sinusitis Phenylephrine 5.047327846
MESH:D012871 Skin Diseases Vitamin E 2.4918709164
MESH:D013088 Spermatocele Ethinyl Estradiol 4.3216709447
MESH:D020521 Stroke Vitamin E 3.7116517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.8811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.3715669648
MESH:D014581 Urticaria Acetaminophen 3.2410982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.5814692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.7815869587 14671159
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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