AutismKB 2.0

Annotation Detail for OSGIN1


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Basic Information Top
Gene Symbol:OSGIN1 ( BDGI,OKL38 )
Gene Full Name: oxidative stress induced growth inhibitor 1
Band: 16q23.3
Quick LinksEntrez ID:29948; OMIM: 607975; Uniprot ID:OSGI1_HUMAN; ENSEMBL ID: ENSG00000140961; HGNC ID: 30093
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1944Breast cancer
2022Liver cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in decreased expression of OSGIN1 mRNAdecreases expression 20406850
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of OSGIN1 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of OSGIN1 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of OSGIN1 mRNAaffects expression 16483693
D019324 beta-Naphthoflavone beta-Naphthoflavone results in increased expression of OSGIN1 mRNAincreases expression 19737606
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of OSGIN1 mRNAaffects cotreatment|decreases expression 18164116
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of OSGIN1 mRNAincreases expression 15735009
20106945
C002791 bismuth tripotassium dicitrate bismuth tripotassium dicitrate results in increased expression of OSGIN1 mRNAincreases expression 15912405
C006780 bisphenol A bisphenol A affects the expression of OSGIN1 mRNAaffects expression 20170705
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of OSGIN1 mRNAincreases expression 12414654
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of OSGIN1 mRNAaffects expression 17484886
D003314 Corn Oil Corn Oil affects the expression of OSGIN1 mRNAaffects expression 16360708
D016572 Cyclosporine Cyclosporine results in increased expression of OSGIN1 mRNAincreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of OSGIN1 mRNAdecreases expression 18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of OSGIN1 mRNAaffects cotreatment|decreases expression 18164116
D019833 Genistein Genistein results in increased expression of OSGIN1 mRNAincreases expression 18847459
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of OSGIN1 mRNAincreases expression 12414654
C041786 palm oil palm oil results in decreased expression of OSGIN1 mRNAdecreases expression 18042831
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of OSGIN1 mRNAincreases expression 17560707
D010634 Phenobarbital Phenobarbital results in decreased expression of OSGIN1 mRNAdecreases expression 19270015
D010795 Phthalic Acids Phthalic Acids results in decreased expression of OSGIN1 mRNAdecreases expression 15728792
D011794 Quercetin Quercetin affects the expression of OSGIN1 mRNAaffects expression 18178720
C009250 sevoflurane sevoflurane affects the expression of OSGIN1 mRNAaffects expression 15967596
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of OSGIN1 mRNAincreases expression 20106945
D001335 Vehicle Emissions Vehicle Emissions results in increased expression of OSGIN1 mRNAincreases expression 19465080
D024483 Vitamin K 3 Vitamin K 3 results in increased expression of OSGIN1 mRNAincreases expression 12414654
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 13.147525203
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 13.146195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 13.1415322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.3718287403
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.2620127859 20464547
MESH:D000230 Adenocarcinoma Genistein 4.2611473722
MESH:D000236 Adenoma Benzo(a)pyrene 10.576695378
MESH:D000236 Adenoma beta-Naphthoflavone 10.5719389873
MESH:D000236 Adenoma Diethylnitrosamine 10.5710737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.2318056438 19061943 16434500 19052882 17162532 17620307
MESH:D018248 Adenoma, Liver Cell Phenobarbital 16.2317620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.2316835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7811748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.0717084956
MESH:D000799 Angioedema Acetaminophen 3.6510982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.8819183758
MESH:D001161 Arteriosclerosis Dietary Fats 3.7015238619
MESH:D001260 Ataxia Telangiectasia Quercetin 4.7815336622
MESH:D001289 Attention Deficit Disorder with Hyperactivity Phthalic Acids 4.2320106747
MESH:D001321 Autistic Disorder Acetaminophen 1.4418445737
MESH:D001327 Autoimmune Diseases Quercetin 4.2219761891
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 2.8712125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6415746008
MESH:D001862 Bone Resorption bisphenol A 3.6911985600
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 3.6517474063 20146248
MESH:D001943 Breast Neoplasms bisphenol A 3.6517123778
MESH:D001943 Breast Neoplasms Dietary Fats 3.6520435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 3.6517474063
MESH:D001943 Breast Neoplasms Genistein 3.6517200150 16873071 16541309
MESH:D001943 Breast Neoplasms Quercetin 3.6518628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.6520435547
MESH:D002105 Cadmium Poisoning Quercetin 5.3516962696
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.5916124888 3786805 15673190 16050911 15700767 16192424 15721981 18705752 16227642 16011737 16097048 10355542
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6516835633
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 13.6016705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 13.603084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 13.6018788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 13.6018971187 18056438 19383236 18494052 20727157 19335982 17055752 16288022 16569478 20084675 20101231 18978308 18210153 20432363 16935385 18785209 20214788 16830150 18788625 18506893 3084413 16698587 19107877 21159647 20512989 19171122 19418558 19394651 10672840 17173139 10737359 17138121 18393292 16540662 19208518 17978847 19701751 16807293 16502159 20935162 19919837 19822196 19052882 18691550 16878318 16681979 16328049 19519916 20514400 17761372 18665156 3581430 19539802 17428255 11831363 20007298 17162532 20524982 16779866
MESH:D006528 Carcinoma, Hepatocellular Genistein 13.6016924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 13.6020007298 1701930 6705139 17173139 20935162
MESH:D006528 Carcinoma, Hepatocellular Quercetin 13.6019519916 12508355
MESH:D002278 Carcinoma in Situ bisphenol A 4.8017123778
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.7717234771
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.0020419170
MESH:D006332 Cardiomegaly Quercetin 6.4519794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.4518670907 16120746 18850075
MESH:D002318 Cardiovascular Diseases Genistein 7.0916332659
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 7.0916936243
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 7.0514694615
MESH:D002386 Cataract Acetaminophen 7.0510977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 10.406135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.4012371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 10.4017174075 21159647 2727394 7505956
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.064080065
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.7919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.7916835633
MESH:D002779 Cholestasis Cyclosporine 2.7819486331
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0315340226 12621046 8697196 16354765 15668235
MESH:D003110 Colonic Neoplasms Genistein 3.8017182828
MESH:D003110 Colonic Neoplasms Quercetin 3.8019440933 11134977 17148506 19056647 16640504 17191121 15741050
MESH:D015179 Colorectal Neoplasms Quercetin 2.1818852136 18095365
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 8.6515095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.6517141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2515322242 10048152 20055451
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.8318551238
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.5819496084
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.8220387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 6.8216647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.8217107852
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 14.5118551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 14.5121346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 14.512444490 15619225 19164858 19739265 19416960 11421492 14550746 10915739 18713872 14986274 19923254 12705907 10774834 11287661 12594235 14725611 12153990 17906064 12540782 12958197 11743745 16081117 16393943 15968718 11461765 19420014 19370779 12392966 11529661 16177239 17562736 16781746 16485898 17522070 11739529 16109766 10663392 16227642 18071297 19085960 11834606
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 14.513732212 4309450 7120509 9327722 15998439 10092053 11566570 21278145 7440962 15027814 15968718 16227642 6623471 16177239 3786805 2869522 19336974 17522070 7179309 10915739 19085960 6884620
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 14.5119107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 14.5120420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9119426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6211462148
MESH:D050171 Dyslipidemias Dietary Fats 3.3218367378
MESH:D004421 Dystonia Phenobarbital 3.831851702
MESH:D004487 Edema perfluorooctanoic acid 6.3817259670 12083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.3811000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7118230668 15322242 16714409
MESH:D004714 Endometrial Hyperplasia Genistein 4.4016402032
MESH:D016889 Endometrial Neoplasms Genistein 3.2411473722
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.8610568697 9294722
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.923659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.6811558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.7920417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.386401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.067750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.833659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9216302075
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 1.9616530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8711564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 17.3516239168 19224547 17595544 15959796 16045604 12631006 12795759 61145
MESH:D005234 Fatty Liver Cyclosporine 17.3519224547
MESH:D005234 Fatty Liver Dietary Fats 17.3519004024 18296743 17967931 19551842
MESH:D005234 Fatty Liver Diethylnitrosamine 17.3520387270 21071580
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2711858732
MESH:D005355 Fibrosis Carbon Tetrachloride 25.7218705752
MESH:D005355 Fibrosis Cyclosporine 25.7212639820 12168785
MESH:D005355 Fibrosis Dietary Fats 25.7218296743
MESH:D005355 Fibrosis Quercetin 25.7219474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 25.7220067830
MESH:D005756 Gastritis Acetaminophen 3.4816983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.038708960
MESH:D005909 Glioblastoma Genistein 6.9416598420
MESH:D005909 Glioblastoma Quercetin 6.9419804834
MESH:D005910 Glioma Quercetin 2.9817643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4010696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.1220471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.1210048152 11294989
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2315720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1611000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.4119110552 19900420
MESH:D006529 Hepatomegaly perfluorooctanoic acid 13.433609246
MESH:D006529 Hepatomegaly Phenobarbital 13.4316109766
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 13.4315340226 12621046 16120746
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.858697196 16959395 15340226 16354765 18606429
MESH:D006930 Hyperalgesia Acetaminophen 7.3616870215
MESH:D006930 Hyperalgesia perfluorooctanoic acid 7.3612083418
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.3416899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.4221332399
MESH:D006943 Hyperglycemia Quercetin 3.8611834736 18262572
MESH:D006949 Hyperlipidemias Dietary Fats 3.4421332399
MESH:D006968 Hypersensitivity, Delayed Corn Oil 5.6211484837
MESH:D006973 Hypertension Cyclosporine 8.1510903974
MESH:D006973 Hypertension Quercetin 8.1518356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.1518670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9015338365
MESH:D007249 Inflammation Dietary Fats 11.1620412841
MESH:D007249 Inflammation Diethylnitrosamine 11.1618785209
MESH:D007249 Inflammation perfluorooctanoic acid 11.1612083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.1612878042 12200463
MESH:D007251 Influenza, Human Quercetin 4.3216624496
MESH:D007333 Insulin Resistance bisphenol A 7.0816393666
MESH:D007333 Insulin Resistance Dietary Fats 7.0811836018 18457598
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1616580747
MESH:D007627 Keloid Quercetin 4.7717086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2515604871
MESH:D007674 Kidney Diseases Acetaminophen 9.4112587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 9.418314463 10903974 18776723
MESH:D007674 Kidney Diseases Quercetin 9.4116962696
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 4.1016518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 6.7616705839
MESH:D007680 Kidney Neoplasms Cyclosporine 6.7612371664
MESH:D007859 Learning Disorders sevoflurane 4.5819212262
MESH:D007938 Leukemia Genistein 6.2418980019 17468513
MESH:D007938 Leukemia Quercetin 6.2417468513
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 5.048812269
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 14.9011408273 11903743 16943688 17157831 17334410 16239168 16221502 17174718 21278145
MESH:D008103 Liver Cirrhosis Dietary Fats 14.9018296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 14.9018407596 18665156 20032147 18522880 19638242
MESH:D008103 Liver Cirrhosis Phenobarbital 14.9021047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.7817761835 18205269 15818738 15362042 18054572 12632512 17805973 13678700 12632514 18166357 18251166 20821823 14748882 18263696 18412020 15052691 16248980 12609069 17557913 16097048 18210741 16033810 15338365 16192424 15730626 18420326 15876570 18395095 18418968 18187930 17640975 15650968 17714472 12586293 18395914 16136751 18472332 12741479 17525996 17944888 17823541 17766677 12666154 18705752 18429990 14512876 16015684 11481614 12445421 12389079 12445418 15925388 14716496 17922224 12898905 14724832 18156304 12958196 16027843 17565644 15673190 18481824 17708605 18317297 12546737 17698563 12667390 15057751 18277467 10355542 18376398 17900296 15996030 15370692 18472094 16638106 17481882 18339082 16116963 18279442 17631135 16011737 15123356 17721639 15893842 18006644 17976157 14620537 15931870 12649538 17869086 14716833 15959796
MESH:D008106 Liver Cirrhosis, Experimental Genistein 4.7817823541
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 4.7812741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.7812878042
MESH:D008107 Liver Diseases Acetaminophen 8.9519014921 12969438 12587719 19784758 16611625 19460945 11587558 16610002
MESH:D008107 Liver Diseases Carbon Tetrachloride 8.9516964402 17285989 16246199 15830285 15720792
MESH:D008107 Liver Diseases Diethylnitrosamine 8.9517034775
MESH:D008107 Liver Diseases Phenobarbital 8.9519363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.9715123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.8516871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.8514706259 16899240
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 28.767678174
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 28.7620195826 21137059
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 28.7619389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 28.7619294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 28.762862719 18978307 12112319 18644402 20452335 19551842 19833225 19690152 16942905 18977376 19427195 19294768 19255062 15175105 19499222 20434301 19073162 20118626 20405173 19426721 15885732 19254457 21167192 2422723 12771043 19090486 10737359 18754104 20137499 20101389 19812893 19850985 19642983 18648771 20583210 20492335 21047994 19996281 21071580 9163691 21278145 19638242 19256749 20501860
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 28.7614757943 18709148
MESH:D008113 Liver Neoplasms Phenobarbital 28.7619073162 8742319 19812893 21047994 15975961 19482888
MESH:D008113 Liver Neoplasms Quercetin 28.7618980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 28.7616984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 26.472876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 26.4718164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 26.4712014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 26.4718164116 19009564 19004024 17174075 3124819 17854601 19519916 16267830 18282651 21159647 18093689 2563599 9362446 18775883 18079962 19539802 16842330 17942915 18544905 18253720 19126423 18308698
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 26.4718308698 17172636 6150874 2563599 1399818
MESH:D008114 Liver Neoplasms, Experimental Quercetin 26.4719519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 26.4712151625
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 6.3520135361 20464547 20064080 18520028 18816296 18569708 20869020 17053015 6695378
MESH:D008175 Lung Neoplasms Diethylnitrosamine 6.3520970405 21163286 20512841 6695378
MESH:D008175 Lung Neoplasms Quercetin 6.3516280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.3511884234 19555203
MESH:D008175 Lung Neoplasms Vehicle Emissions 6.359255578
MESH:D008325 Mammary Neoplasms, Experimental Genistein 2.8214578162 12929590
MESH:D008545 Melanoma Vitamin K 3 3.1519082730
MESH:D008546 Melanoma, Experimental Acetaminophen 3.3819513568
MESH:D008569 Memory Disorders sevoflurane 4.5719212262
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5916801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.0416381670
MESH:D009203 Myocardial Infarction Genistein 5.7317141266
MESH:D009203 Myocardial Infarction Quercetin 5.7319595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8712213967
MESH:D015428 Myocardial Reperfusion Injury Genistein 8.2217141266
MESH:D015428 Myocardial Reperfusion Injury Quercetin 8.2219207477
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.2817484760
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.6718551238 7678174
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.493581430 9029167
MESH:D009369 Neoplasms Benzo(a)pyrene 4.8211141357
MESH:D009369 Neoplasms Quercetin 4.8215185748
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1219348381 18481113
MESH:D009421 Nervous System Malformations bisphenol A 15.3411399458 16427766
MESH:D009421 Nervous System Malformations Genistein 15.3416427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 15.3414600291
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.6618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.6620387270
MESH:D020078 Neurogenic Inflammation Quercetin 4.1817929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9220387270
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.769802331
MESH:D009765 Obesity Dietary Fats 2.2419632207 18457598 20132043 11836018 18674790 16723640 21332399 17217161 20518802
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.5816049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 8.5814694615
MESH:D010018 Osteomalacia Phenobarbital 4.1717016548
MESH:D010024 Osteoporosis Genistein 3.1419401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 9.5416169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 9.5419495926
MESH:D010049 Ovarian Diseases bisphenol A 4.8011985600
MESH:D010051 Ovarian Neoplasms Genistein 4.8919005980
MESH:D010051 Ovarian Neoplasms Quercetin 4.8919005980
MESH:D010146 Pain Acetaminophen 2.2416870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.2616540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 8.2616965848
MESH:D010190 Pancreatic Neoplasms Quercetin 8.2616965848
MESH:D010212 Papilloma Hydrogen Peroxide 3.9012065085
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0612520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3718163543
MESH:D011230 Precancerous Conditions Corn Oil 26.9814668109
MESH:D011230 Precancerous Conditions Cyclosporine 26.9812371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 26.982563599
MESH:D011230 Precancerous Conditions Phenobarbital 26.982563599
MESH:D011230 Precancerous Conditions Quercetin 26.9819056647
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 15.2110548101
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 15.2117132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 15.2111896295 11222880 11399792 11118676
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.0320887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.1317292933
MESH:D011471 Prostatic Neoplasms bisphenol A 2.1316740699
MESH:D011471 Prostatic Neoplasms Genistein 2.1315256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms Quercetin 2.1317292933 14715546
MESH:D019310 Pseudolymphoma Phenobarbital 4.3012752131
MESH:D011565 Psoriasis Cyclosporine 2.1616882103
MESH:D011629 Puberty, Precocious bisphenol A 4.5910548101
MESH:D012135 Respiratory Sounds Vehicle Emissions 5.0318950799
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6518990726
MESH:D012554 Schistosomiasis japonica Quercetin 5.3516862918
MESH:D012640 Seizures 2,6-dinitrotoluene 5.5018551238
MESH:D012640 Seizures Phenobarbital 5.503137016 4039156 11442880 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.636407741
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 12.8319755658 10029692
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 12.8312065085
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 12.838532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 12.8316192470
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.2820155912 2093021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.2818456281
MESH:D019966 Substance-Related Disorders bisphenol A 3.7916045194 16684133
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7112697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.707505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 6.701399818
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 11.3916049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 11.3917053015
MESH:D001749 Urinary Bladder Neoplasms Quercetin 11.3916720314
MESH:D001749 Urinary Bladder Neoplasms Vehicle Emissions 11.3911144890
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.1310091137
MESH:D014581 Urticaria Acetaminophen 2.8010982225
MESH:D014591 Uterine Diseases bisphenol A 4.8214652134
MESH:D014605 Uveitis Cyclosporine 3.791336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4012125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0615886252
MESH:D015430 Weight Gain Dietary Fats 3.5816723640
MESH:D014985 Xerophthalmia Cyclosporine 4.2517120751
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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