AutismKB 2.0

Annotation Detail for STRN3


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Basic Information Top
Gene Symbol:STRN3 ( SG2NA )
Gene Full Name: striatin, calmodulin binding protein 3
Band: 14q12
Quick LinksEntrez ID:29966; OMIM: NA; Uniprot ID:STRN3_HUMAN; ENSEMBL ID: ENSG00000196792; HGNC ID: 15720
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of STRN3 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of STRN3 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of STRN3 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of STRN3 mRNAincreases expression 20458559
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of STRN3 mRNAdecreases expression 19150397
C017947 sodium arsenite sodium arsenite results in decreased expression of STRN3 mRNAdecreases expression 19072884
C004648 testosterone enanthate testosterone enanthate affects the expression of STRN3 mRNAaffects expression 17440010
C020806 tetrabromobisphenol A tetrabromobisphenol A affects the expression of STRN3 mRNAaffects expression 18976794
C423915 TO-901317 TO-901317 results in increased expression of STRN3 mRNAincreases expression 15302862
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.8418287403
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3319825857 11798837
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 5.0215276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.2217306315 16712894
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 3.8816206674
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.5511589617
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 6.8116705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 6.8116705839
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 6.8115553829 14691202 15073043 16217749 11135700
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 6.8117306315 15276417 16507464
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.1919014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.3112490120
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 2.4318572023
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 12.016135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 12.0120889678
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 12.0119524636 20056578
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.4212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D003490 Cyanosis 2,4-dinitrotoluene 11.7718551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 11.7718551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.3215213294
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 4.0321346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 4.0321346803 18551238
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.6120426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.6112903497
MESH:D005234 Fatty Liver arsenic trioxide 3.4915073043
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.5016904648
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.9616452187
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 6.0617440010
MESH:D006689 Hodgkin Disease sodium arsenite 3.3312676792
MESH:D007248 Infertility, Male sodium arsenite 3.1215346721 12646999
MESH:D007674 Kidney Diseases sodium arsenite 2.9120008137
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 7.9416705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 7.9416705839
MESH:D007938 Leukemia arsenic trioxide 2.9215070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.0012560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.5916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.5814633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.9719077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1616467208 17050201 19850784 16968895 20471514
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.3419035177 15336539 19642359 17869043 12018890 15213294 17712046 11161223 12712474 19075265 16112521 17649720 17107899 16330433 15748426 19225113 9834237 16891316 17217047 16966277 16823087 15622746 16331271 12679006 11468182
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.5916882451
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 7.887678174
MESH:D008113 Liver Neoplasms arsenic trioxide 7.8814682389
MESH:D008113 Liver Neoplasms sodium arsenite 7.8816712894 15276417
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 6.372876786 2876784 6135515
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 6.3720377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.5115213294
MESH:D008171 Lung Diseases sodium arsenite 3.3019095001
MESH:D008175 Lung Neoplasms arsenic trioxide 2.5811798837 19825857
MESH:D008175 Lung Neoplasms sodium arsenite 2.5816712894 15276417 17306315 19931552 17077188
MESH:D008545 Melanoma sodium arsenite 2.0516487513 19082730
MESH:D009101 Multiple Myeloma arsenic trioxide 3.2511468182 14977855 19417148 19549372 15949261
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.9918349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.2516105982 16882451
MESH:D009336 Necrosis 2,4-dinitrotoluene 11.3218551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 11.3218551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.2016624393
MESH:D009369 Neoplasms sodium arsenite 2.5811559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.9220056578
MESH:D009436 Neural Tube Defects arsenic trioxide 7.7610525206
MESH:D009436 Neural Tube Defects sodium arsenite 7.7612854658
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 9.5412819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 9.5416049721
MESH:D010051 Ovarian Neoplasms arsenic trioxide 5.0916624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms sodium arsenite 5.0915276417 17306315
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.5815580305
MESH:D010235 Paraganglioma arsenic trioxide 4.3819927285
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.2519131511
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.2516039940
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.2016646077
MESH:D012640 Seizures 2,4-dinitrotoluene 6.3218551238
MESH:D012640 Seizures 2,6-dinitrotoluene 6.3218551238
MESH:D012878 Skin Neoplasms sodium arsenite 2.7818572023 19524636
MESH:D016135 Spinal Dysraphism sodium arsenite 3.9512854658
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.2419014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.2415213294
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 12.5216049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 12.5216049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 12.5220435036 11780464 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 12.5216712894 11723127 17306315 16452187
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 12.9610091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 12.9610091137
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.9611813266
MESH:D014652 Vascular Diseases sodium arsenite 4.7117056641
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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