Annotation Detail for LRP12
Basic Information
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| Gene Symbol: | LRP12 ( DKFZp781F1053,FLJ12929,ST7 ) |
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| Gene Full Name: | low density lipoprotein receptor-related protein 12 |
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| Band: | 8q22.3 |
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| Quick Links | Entrez ID:29967; OMIM: NA; Uniprot ID:LRP12_HUMAN; ENSEMBL ID: ENSG00000147650; HGNC ID: 31708 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of LRP12 mRNA | affects expression | 21346803
|
| D016604 |
Aflatoxin B1 |
Aflatoxin B1 affects the expression of LRP12 protein | affects expression | 20106945
|
| D016572 |
Cyclosporine |
Cyclosporine results in increased expression of LRP12 mRNA | increases expression | 20106945
|
| D007657 |
Ketone Bodies |
Ketone Bodies results in decreased expression of LRP12 mRNA | decreases expression | 16807920
|
| C013598 |
methoxyacetic acid |
methoxyacetic acid results in increased expression of LRP12 mRNA | increases expression | 18199887
|
| D018038 |
Sodium Selenite |
Sodium Selenite results in decreased expression of LRP12 mRNA | decreases expression | 18175754
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
methoxyacetic acid |
5.30 | 12805644 1761404 1761407 15959878 3652986 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
3.15 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Aflatoxin B1 |
3.15 | 12907637 21507988 12619106 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
7.27 | 6135515 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
7.27 | 12371664 |
| MESH:D002779 |
Cholestasis |
|
Cyclosporine |
3.14 | 19486331 |
| MESH:D019457 |
Chromosome Breakage |
|
Sodium Selenite |
5.17 | 15894690 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
4.44 | 18551238 |
| MESH:D003920 |
Diabetes Mellitus |
|
Sodium Selenite |
4.06 | 16285004 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
4.22 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Sodium Selenite |
4.22 | 15131321 |
| MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
3.18 | 19224547 |
| MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.56 | 12639820 12168785 |
| MESH:D005532 |
Foot Deformities, Congenital |
|
methoxyacetic acid |
6.10 | 3652986 |
| MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.68 | 8708960 |
| MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
4.88 | 15720958 |
| MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.19 | 10903974 |
| MESH:D007333 |
Insulin Resistance |
|
Sodium Selenite |
3.47 | 14714311 |
| MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
4.96 | 15604871 |
| MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
2.50 | 18776723 10903974 8314463 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
8.18 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
8.18 | 12371664 |
| MESH:D017880 |
Limb Deformities, Congenital |
|
methoxyacetic acid |
4.96 | 15959878 12805644 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
4.93 | 7678174 |
| MESH:D008113 |
Liver Neoplasms |
|
Aflatoxin B1 |
4.93 | 9163691 15890375 2125692 18177683 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
6.58 | 2876784 6135515 2876786 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Aflatoxin B1 |
6.58 | 8603461 |
| MESH:D008175 |
Lung Neoplasms |
|
Aflatoxin B1 |
1.88 | 14755239 |
| MESH:D016393 |
Lymphoma, B-Cell |
|
Sodium Selenite |
4.41 | 14737004 |
| MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.31 | 16801185 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
4.32 | 18551238 7678174 |
| MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
4.96 | 17954296 |
| MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.57 | 18481113 19348381 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
3.74 | 16049721 |
| MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.51 | 12371664 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Sodium Selenite |
3.34 | 18760546 |
| MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.31 | 16882103 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
2.74 | 18551238 |
| MESH:D013576 |
Syndactyly |
|
methoxyacetic acid |
6.01 | 1761407 1761404 |
| MESH:D013733 |
Testicular Diseases |
|
methoxyacetic acid |
5.79 | 6499806 18486176 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
2.39 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
4.78 | 10091137 |
| MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.50 | 1336536 |
| MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
4.96 | 17120751 |
Related Pathway Information