AutismKB 2.0

Annotation Detail for SCHIP1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SCHIP1 ( FLJ39160,SCHIP-1 )
Gene Full Name: schwannomin interacting protein 1
Band: 3q25.33
Quick LinksEntrez ID:29970; OMIM: NA; Uniprot ID:SCHI1_HUMAN; ENSEMBL ID: ENSG00000151967,ENSG00000214216; HGNC ID: 15678
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
Celiac Disease
IMMUNE
quantitative traits
Desease Name
Quantitative traits
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SCHIP1 mRNAaffects cotreatment|increases expression 18164116
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of SCHIP1 mRNAincreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SCHIP1 mRNAdecreases expression 19150397
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of SCHIP1 mRNAaffects expression 17484886
D016572 Cyclosporine Cyclosporine results in decreased expression of SCHIP1 mRNAdecreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of SCHIP1 mRNAdecreases expression 18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SCHIP1 mRNAaffects cotreatment|increases expression 18164116
D007657 Ketone Bodies Ketone Bodies results in increased expression of SCHIP1 mRNAincreases expression 16807920
D008942 Mitoxantrone SCHIP1 protein affects the susceptibility to Mitoxantroneaffects response to substance 16217747
C041786 palm oil palm oil results in decreased expression of SCHIP1 mRNAdecreases expression 18042831
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SCHIP1 mRNAaffects binding|increases activity|increases expression 19710929
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.2718653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0120127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 11.666695378
MESH:D000236 Adenoma beta-Naphthoflavone 11.6619389873
MESH:D000236 Adenoma Diethylnitrosamine 11.666695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 10.7517162532 19052882 18056438 19061943 17620307 16434500
MESH:D018248 Adenoma, Liver Cell pirinixic acid 10.7516434500
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.2519183758
MESH:D001161 Arteriosclerosis Dietary Fats 4.0615238619
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.2919483382
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.8817474063 20146248
MESH:D001943 Breast Neoplasms Dietary Fats 1.8820435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.8817474063
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.953786805 16124888 15673190 15721981 16192424 15700767 16011737 16097048 18705752 16227642 16050911 10355542
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 3.0718788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 3.0717978847 20432363 20935162 18665156 16807293 19107877 20007298 16681979 3581430 10737359 17428255 16698587 17138121 16569478 20084675 20514400 19335982 19701751 17761372 19539802 20524982 20101231 18978308 20727157 19394651 18210153 19171122 19383236 18785209 17055752 18506893 18788625 16288022 20214788 16779866 16935385 11831363 18056438 19822196 16878318 21159647 20512989 19519916 19919837 17173139 18971187 17162532 3084413 19418558 10672840 18494052 18393292 19208518 16328049 16540662 16502159 18691550 16830150 19052882
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.0820419170
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.7120889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 11.7112371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 11.7117174075 21159647 2727394 7505956
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.8119052882
MESH:D002779 Cholestasis Cyclosporine 8.1019486331
MESH:D002779 Cholestasis pirinixic acid 8.1019176532
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4818249437
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2220387270
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 4.042869522 19085960 21278145 6884620 10092053 7120509 9327722 6623471 16227642 15968718 15027814 16177239 10915739 15998439 17522070 4309450 19336974 7440962 7179309 3786805 11566570 3732212
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 4.0419107877
MESH:D050171 Dyslipidemias Dietary Fats 3.5518367378
MESH:D004487 Edema pirinixic acid 2.6212083418
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.3316302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.4620426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.4616530937
MESH:D005234 Fatty Liver Carbon Tetrachloride 26.2412795759 17595544 19224547 16239168 61145 15959796 12631006 16045604
MESH:D005234 Fatty Liver Cyclosporine 26.2419224547
MESH:D005234 Fatty Liver Dietary Fats 26.2418296743 17967931 19551842 19004024
MESH:D005234 Fatty Liver Diethylnitrosamine 26.2421071580 20387270
MESH:D005234 Fatty Liver pirinixic acid 26.2419236843 20131406
MESH:D005355 Fibrosis Carbon Tetrachloride 15.8518705752
MESH:D005355 Fibrosis Cyclosporine 15.8512639820 12168785
MESH:D005355 Fibrosis Dietary Fats 15.8518296743
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.418708960
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.7220471113
MESH:D006331 Heart Diseases Mitoxantrone 4.2416019553
MESH:D006333 Heart Failure pirinixic acid 2.6220558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.6215720958
MESH:D006505 Hepatitis Carbon Tetrachloride 3.7619110552 19900420
MESH:D006529 Hepatomegaly pirinixic acid 3.1718467677 19176532 19772884 16221962
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.7316899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.7321332399
MESH:D006943 Hyperglycemia pirinixic acid 3.3120558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.7621332399
MESH:D006973 Hypertension Cyclosporine 2.1410903974
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.2615338365
MESH:D007249 Inflammation Dietary Fats 5.3320412841
MESH:D007249 Inflammation Diethylnitrosamine 5.3318785209
MESH:D007333 Insulin Resistance Dietary Fats 7.5418457598 11836018
MESH:D007333 Insulin Resistance pirinixic acid 7.5416306350
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.6615604871
MESH:D007674 Kidney Diseases Cyclosporine 2.418314463 18776723 10903974
MESH:D007680 Kidney Neoplasms Cyclosporine 2.8512371664
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Mitoxantrone 3.8418172266
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 11.4411408273 11903743 16943688 17334410 17157831 16221502 21278145 16239168 17174718
MESH:D008103 Liver Cirrhosis Dietary Fats 11.4418296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 11.4418407596 18522880 20032147 19638242 18665156
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 2.3615818738 14512876 12445421 17900296 17823541 17565644 18418968 12609069 17640975 17698563 18156304 18339082 17721639 15931870 12667390 15893842 10355542 11481614 18251166 12389079 15876570 16033810 18472332 15052691 13678700 17869086 18376398 14724832 18429990 12649538 18210741 18263696 17805973 17631135 18412020 12958196 15673190 15370692 16248980 17976157 12445418 16011737 12741479 15362042 12586293 18472094 16015684 18481824 15730626 14620537 14716496 17922224 17708605 15650968 12632514 15996030 15338365 18705752 18395914 18006644 18277467 16116963 18279442 18395095 12666154 14716833 16027843 16192424 12546737 16638106 12898905 15057751 18054572 16136751 17525996 16097048 17761835 15925388 14748882 18420326 17557913 18166357 17714472 17481882 18205269 15123356 18317297 18187930 20821823 15959796 17944888 17766677 12632512
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.3615474484
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.1816246199 16964402 17285989 15720792 15830285
MESH:D008107 Liver Diseases Diethylnitrosamine 4.1817034775
MESH:D017093 Liver Failure Carbon Tetrachloride 4.3415123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.8216899240 14706259
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 14.7720195826 21137059
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 14.7719389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 14.7719294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 14.7710737359 18754104 21071580 20118626 9163691 18648771 19073162 20501860 19812893 20434301 21047994 18978307 19427195 2422723 2862719 18977376 16942905 19551842 19638242 19294768 12112319 19426721 20452335 19090486 20405173 19690152 21278145 19996281 21167192 19255062 19642983 15175105 20137499 19254457 20583210 20101389 12771043 15885732 19833225 19850985 19256749 18644402 20492335 19499222
MESH:D008113 Liver Neoplasms pirinixic acid 14.7720007298 15890375 16377806
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 10.4218164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 10.4212014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 10.4218164116 21159647 9362446 17854601 18079962 19009564 18093689 2563599 16842330 18775883 3124819 17174075 18544905 16267830 18282651 19004024 17942915 19539802 18308698 19519916 18253720 19126423
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.416695378 20464547 18569708 20064080 18816296 18520028 20135361 17053015 20869020
MESH:D008175 Lung Neoplasms Diethylnitrosamine 2.4120970405 6695378 20512841 21163286
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.0116801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.3016381670
MESH:D009135 Muscular Diseases pirinixic acid 3.6816239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.1919151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.0516411023
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.613581430 9029167
MESH:D009369 Neoplasms Benzo(a)pyrene 8.7111141357
MESH:D009369 Neoplasms Mitoxantrone 8.7116640825
MESH:D009369 Neoplasms pirinixic acid 8.7117405874
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.6617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.4119348381 18481113
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.4620387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.3320387270
MESH:D009765 Obesity Dietary Fats 4.5418457598 21332399 20132043 19632207 17217161 18674790 16723640 20518802 11836018
MESH:D009765 Obesity pirinixic acid 4.5420558911
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.4616540662
MESH:D011230 Precancerous Conditions Cyclosporine 9.3612371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 9.362563599
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9517292933
MESH:D011565 Psoriasis Cyclosporine 2.2716882103
MESH:D015427 Reperfusion Injury pirinixic acid 2.4519058328
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.4310029692 19755658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.3620155912 2093021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.3618456281
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 3.097505956
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2217053015
MESH:D014605 Uveitis Cyclosporine 4.201336536
MESH:D015430 Weight Gain Dietary Fats 3.8616723640
MESH:D014985 Xerophthalmia Cyclosporine 4.6617120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34997
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved