AutismKB 2.0

Annotation Detail for GYS2


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Basic Information Top
Gene Symbol:GYS2 ( - )
Gene Full Name: glycogen synthase 2 (liver)
Band: 12p12.1
Quick LinksEntrez ID:2998; OMIM: 138571; Uniprot ID:GYS2_HUMAN; ENSEMBL ID: ENSG00000111713; HGNC ID: 4707
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-5067glycogen biosynthesis II (from UDP-D-Glucose)
Pathway IDPathway Name
hsa04910Insulin signaling pathway
hsa00500Starch and sucrose metabolism
Pathway IDPathway Name
Metabolism of carbohydrates
No data
Pathway IDPathway Name
P00026Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
No data
Related Diseases/Disorders Top
Desease IDDesease Name
Inherited disorders of carbohydrate metabolism
H00069Glycogen storage disease (GSD)
Genetic disorders
No data
No data
No data
Desease Name
Glycogen storage disease, type 0
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C026137 3-hydroxyacetanilide 3-hydroxyacetanilide results in decreased expression of GYS2 mRNAdecreases expression 18544908
C520164 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid results in increased expression of GYS2 mRNAincreases expression 17437057
C520164 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid results in increased expression of GYS2 proteinincreases expression 17437057
D000082 Acetaminophen Acetaminophen affects the expression of GYS2 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in decreased expression of GYS2 mRNAdecreases expression 18544908
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of GYS2 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GYS2 mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of GYS2 mRNAdecreases expression 20106945
C095105 bexarotene bexarotene results in decreased expression of GYS2 mRNAdecreases expression 16648578
C039671 ciglitazone ciglitazone results in increased expression of GYS2 mRNAincreases expression 17437057
C039671 ciglitazone ciglitazone results in increased expression of GYS2 proteinincreases expression 17437057
D016572 Cyclosporine Cyclosporine results in decreased expression of GYS2 mRNAdecreases expression 20106945
D016572 Cyclosporine Cyclosporine results in decreased expression of GYS2 mRNAdecreases expression 19224547
C014347 decitabine decitabine results in increased expression of GYS2 mRNAincreases expression 15251184
C014347 decitabine [Tetrachlorodibenzodioxin co-treated with decitabine] results in increased expression of GYS2 mRNAaffects cotreatment|increases expression 15251184
D004041 Dietary Fats Dietary Fats results in decreased expression of GYS2 mRNAdecreases expression 18042831
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of GYS2 mRNAdecreases expression 19638242
D004958 Estradiol Estradiol results in decreased expression of GYS2 mRNAdecreases expression 20106945
D008701 Methapyrilene Methapyrilene results in decreased expression of GYS2 mRNAdecreases expression 16393664
C041786 palm oil palm oil results in decreased expression of GYS2 mRNAdecreases expression 18042831
D010634 Phenobarbital Phenobarbital results in increased expression of GYS2 mRNAincreases expression 19270015
C006253 pirinixic acid pirinixic acid results in decreased expression of GYS2 mRNAdecreases expression 17950772
C006253 pirinixic acid pirinixic acid results in increased expression of GYS2 mRNAincreases expression 17437057
C031280 pyrazole pyrazole results in decreased expression of GYS2 mRNAdecreases expression 17945193
C089730 rosiglitazone rosiglitazone results in increased expression of GYS2 mRNAincreases expression 17437057
C089730 rosiglitazone rosiglitazone results in increased expression of GYS2 proteinincreases expression 17437057
C009250 sevoflurane sevoflurane affects the expression of GYS2 mRNAaffects expression 15967596
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of GYS2 mRNAdecreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with decitabine] results in increased expression of GYS2 mRNAaffects cotreatment|increases expression 15251184
D013752 Tetracycline Tetracycline results in decreased expression of GYS2 mRNAdecreases expression 19224547
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 7.866195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.8615322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.4318287403
MESH:D055371 Acute Lung Injury pirinixic acid 2.9918653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.1720127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 4.1711473722
MESH:D000236 Adenoma Benzo(a)pyrene 6.386695378
MESH:D000236 Adenoma Diethylnitrosamine 6.3810737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 23.7817162532 19052882 16434500 17620307 18056438 19061943
MESH:D018248 Adenoma, Liver Cell Phenobarbital 23.7817620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 23.7816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 23.7816835633
MESH:D000544 Alzheimer Disease rosiglitazone 2.8219621015
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8311748828
MESH:D000799 Angioedema Acetaminophen 3.7110982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.9419183758
MESH:D001161 Arteriosclerosis Dietary Fats 3.7615238619
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.3719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.3712125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6815746008
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 3.6920146248 17474063
MESH:D001943 Breast Neoplasms bexarotene 3.6916344269 16818667
MESH:D001943 Breast Neoplasms decitabine 3.6919208741 18320071
MESH:D001943 Breast Neoplasms Dietary Fats 3.6920435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 3.6917474063
MESH:D001943 Breast Neoplasms Estradiol 3.6917289903 16675129 12948864 17261762 19861407 17018787 14630087 18497071
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.6920435547
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3316111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6916835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.643084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 8.6421507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 8.6416807293 19052882 19519916 18506893 11831363 20727157 18210153 3084413 20935162 19919837 19394651 19701751 20084675 20214788 17428255 19208518 18785209 17055752 16681979 17761372 18691550 16878318 3581430 16569478 19335982 18978308 18056438 16328049 20432363 18788625 18494052 16502159 16698587 17173139 19107877 19539802 19383236 20514400 20101231 16935385 16830150 17138121 20524982 10672840 17162532 18393292 20007298 16288022 19822196 17978847 16540662 19171122 16779866 20512989 19418558 10737359 21159647 18665156 18971187
MESH:D006528 Carcinoma, Hepatocellular Estradiol 8.6416924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 8.6417173139 20007298 6705139 1701930 20935162
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.1816247446
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.5520419170
MESH:D002294 Carcinoma, Squamous Cell decitabine 4.5519215824
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3018670907 16120746 18850075
MESH:D002386 Cataract Acetaminophen 2.5110977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.6312371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 10.6317174075 21159647 2727394 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 10.6318566989
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.124080065
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.9519052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.9516835633
MESH:D002779 Cholestasis Cyclosporine 7.4319486331
MESH:D002779 Cholestasis pirinixic acid 7.4319176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0515668235 15340226 12621046 8697196 16354765
MESH:D003110 Colonic Neoplasms decitabine 2.3117616700
MESH:D015179 Colorectal Neoplasms decitabine 2.1018981723
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9517141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2510048152 15322242 20055451
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3718249437
MESH:D003920 Diabetes Mellitus rosiglitazone 4.1917446233
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.9820387270
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 6.9812642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.9817107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.3019279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.6219420014 14725611 2444490 12705907 12392966 16081117 19923254 11421492 19164858 17522070 11287661 16781746 11743745 16177239 10663392 11834606 16393943 19085960 18713872 10915739 12540782 18071297 11739529 11461765 19739265 14986274 14550746 16109766 11529661 17906064 17562736 19416960 15619225 16227642 12594235 12958197 19370779 10774834 12153990 15968718 16485898
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 11.6219107877
MESH:D056486 Drug-Induced Liver Injury pyrazole 11.6212499123
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.6220420201
MESH:D056486 Drug-Induced Liver Injury Tetracycline 11.6217522070
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6611462148
MESH:D050171 Dyslipidemias Dietary Fats 3.3618367378
MESH:D004421 Dystonia Phenobarbital 3.881851702
MESH:D004487 Edema pirinixic acid 10.7812083418
MESH:D004487 Edema rosiglitazone 10.7812083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.7812711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7715322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental ciglitazone 5.3416844232
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.9919294695
MESH:D016889 Endometrial Neoplasms Estradiol 2.9011473722 18566989 19148513
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.9110568697 9294722
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.983659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.743922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.8220417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.436401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.127750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.893659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9916302075
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 1.9816530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9111564622
MESH:D005234 Fatty Liver Cyclosporine 29.1619224547
MESH:D005234 Fatty Liver Dietary Fats 29.1617967931 19004024 18296743 19551842
MESH:D005234 Fatty Liver Diethylnitrosamine 29.1620387270 21071580
MESH:D005234 Fatty Liver pirinixic acid 29.1619236843 20131406
MESH:D005234 Fatty Liver rosiglitazone 29.1619196556
MESH:D005234 Fatty Liver Tetracycline 29.1616917069 19224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3311858732
MESH:D005355 Fibrosis Cyclosporine 13.9612168785 12639820
MESH:D005355 Fibrosis Dietary Fats 13.9618296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 13.9620067830
MESH:D005756 Gastritis Acetaminophen 3.5516983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.098708960
MESH:D006008 Glycogen Storage Disease marker/mechanism
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4710696789
MESH:D006258 Head and Neck Neoplasms decitabine 3.4019215824
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.2220471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.2210048152 11294989
MESH:D006333 Heart Failure pirinixic acid 2.4620558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2111000095
MESH:D006529 Hepatomegaly Phenobarbital 13.6316109766
MESH:D006529 Hepatomegaly pirinixic acid 13.6319176532 16221962 19772884 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 13.6315340226 12621046 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.9015709030
MESH:D019584 Hot Flashes Estradiol 3.6217088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.928697196 16354765 15340226 18606429 16959395
MESH:D006930 Hyperalgesia Acetaminophen 7.5416870215
MESH:D006930 Hyperalgesia rosiglitazone 7.5412083418
MESH:D006937 Hypercholesterolemia Dietary Fats 3.4721332399
MESH:D006943 Hyperglycemia pirinixic acid 3.0720558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.4921332399
MESH:D006973 Hypertension Cyclosporine 4.7810903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.7818670907 18850075
MESH:D007248 Infertility, Male decitabine 3.1217581917
MESH:D007249 Inflammation Dietary Fats 11.4220412841
MESH:D007249 Inflammation Diethylnitrosamine 11.4218785209
MESH:D007249 Inflammation rosiglitazone 11.4212083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.4212878042 12200463
MESH:D007333 Insulin Resistance Dietary Fats 16.9611836018 18457598
MESH:D007333 Insulin Resistance Estradiol 16.9616393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 16.9616306350
MESH:D007333 Insulin Resistance rosiglitazone 16.9616306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2116580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3115604871
MESH:D007674 Kidney Diseases Acetaminophen 9.5415629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 9.548314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 9.5415618244
MESH:D007680 Kidney Neoplasms Cyclosporine 6.9212371664
MESH:D007680 Kidney Neoplasms Estradiol 6.9215610895
MESH:D007859 Learning Disorders sevoflurane 4.6419212262
MESH:D007938 Leukemia decitabine 3.0118980019 19235587
MESH:D007951 Leukemia, Myeloid decitabine 3.8819117987 18454857 17236224
MESH:D015470 Leukemia, Myeloid, Acute decitabine 2.3619387464 19010910 18206229 18460780 18704418 17679729
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.3318055864
MESH:D008103 Liver Cirrhosis Dietary Fats 10.6118296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.6118665156 18407596 18522880 19638242 20032147
MESH:D008103 Liver Cirrhosis Phenobarbital 10.6121047994
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.8214716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.8215474484
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 4.8217347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.8212878042
MESH:D008107 Liver Diseases Acetaminophen 6.2819460945 16610002 19784758 16611625 12969438 11587558 19014921 12587719
MESH:D008107 Liver Diseases Diethylnitrosamine 6.2817034775
MESH:D008107 Liver Diseases Phenobarbital 6.2819363144
MESH:D017114 Liver Failure, Acute Acetaminophen 3.1216871587 17185352
MESH:D008113 Liver Neoplasms Aflatoxin B1 21.1518177683 2125692 15890375 9163691
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 21.1520195826 21137059
MESH:D008113 Liver Neoplasms Diethylnitrosamine 21.1519256749 21167192 20405173 19427195 20492335 15885732 10737359 19833225 9163691 19642983 19812893 18978307 19690152 20118626 15175105 20501860 18977376 16942905 19254457 19551842 19294768 19073162 19426721 21047994 12771043 19850985 18644402 20434301 20137499 19996281 19638242 20583210 18754104 19090486 21278145 21071580 2862719 19255062 20452335 2422723 19499222 18648771 12112319 20101389
MESH:D008113 Liver Neoplasms Methapyrilene 21.1515890375
MESH:D008113 Liver Neoplasms Phenobarbital 21.1519812893 19482888 15975961 21047994 8742319 19073162
MESH:D008113 Liver Neoplasms pirinixic acid 21.1520007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 21.1516984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 13.448603461
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.4419009564 18253720 18079962 19004024 19539802 18164116 16267830 18282651 9362446 19126423 18544905 21159647 18775883 18308698 17942915 16842330 17174075 19519916 2563599 3124819 18093689 17854601
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 13.4417172636 1399818 2563599 18308698 6150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.4412151625
MESH:D008175 Lung Neoplasms Aflatoxin B1 8.3614755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 8.3620464547 17053015 18816296 20869020 18569708 20135361 18520028 6695378 20064080
MESH:D008175 Lung Neoplasms bexarotene 8.3617849452
MESH:D008175 Lung Neoplasms ciglitazone 8.3615899809
MESH:D008175 Lung Neoplasms Diethylnitrosamine 8.3621163286 20970405 20512841 6695378
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.3611884234 19555203
MESH:D008223 Lymphoma decitabine 3.3319470736
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 5.0211161223
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 9.6615591091 19196722 19196723
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 9.6617203775 11807958 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 9.6616827153
MESH:D020149 Manganese Poisoning Estradiol 4.3519453300
MESH:D008545 Melanoma decitabine 2.2316505122 17785578
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4419513568
MESH:D008569 Memory Disorders sevoflurane 4.6219212262
MESH:D024821 Metabolic Syndrome X rosiglitazone 4.2717261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6616801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.0916381670
MESH:D009101 Multiple Myeloma decitabine 3.2518172295
MESH:D009135 Muscular Diseases pirinixic acid 3.3816239165
MESH:D009190 Myelodysplastic Syndromes decitabine 3.3116882708 19010910 18608210 19157545
MESH:D009203 Myocardial Infarction pirinixic acid 2.0919151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.9116810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.9116411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.3417484760
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.529029167 3581430
MESH:D009369 Neoplasms Benzo(a)pyrene 7.8611141357
MESH:D009369 Neoplasms decitabine 7.8617925555 19116145 19470736
MESH:D009369 Neoplasms pirinixic acid 7.8617405874
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 4.6519196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6017289903
MESH:D009395 Nephritis, Interstitial Tetracycline 4.669884423
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1719348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 9.0416427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.0414600291
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.8218514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.8220387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9920387270
MESH:D009765 Obesity Dietary Fats 4.3218457598 17217161 16723640 21332399 18674790 19632207 20132043 11836018 20518802
MESH:D009765 Obesity pirinixic acid 4.3220558911
MESH:D010018 Osteomalacia Phenobarbital 4.2317016548
MESH:D010051 Ovarian Neoplasms decitabine 4.7819331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 4.7819401270
MESH:D010146 Pain Acetaminophen 2.2916870215
MESH:D010190 Pancreatic Neoplasms decitabine 8.3819294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.3816540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 8.3816965848
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1212520081
MESH:D010391 Pemphigoid, Bullous Tetracycline 5.3011026799
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4318163543
MESH:D011230 Precancerous Conditions Cyclosporine 14.6212371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 14.622563599
MESH:D011230 Precancerous Conditions Phenobarbital 14.622563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0611118676 11896295 11399792 11222880
MESH:D055728 Primary Myelofibrosis decitabine 4.6017616702
MESH:D017096 Prion Diseases Tetracycline 5.2810903871
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.7620887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.1517292933
MESH:D011471 Prostatic Neoplasms Estradiol 3.1516740699
MESH:D019310 Pseudolymphoma Phenobarbital 4.3712752131
MESH:D011565 Psoriasis Cyclosporine 2.1816882103
MESH:D015427 Reperfusion Injury pirinixic acid 2.3219058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7118990726
MESH:D012208 Rhabdomyosarcoma decitabine 4.2819155313
MESH:D012640 Seizures Phenobarbital 2.6116876388 3137016 4039156 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 4.696407741
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.2710029692 19755658
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.2716192470
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.302093021 20155912
MESH:D013274 Stomach Neoplasms decitabine 3.3019037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.3018456281
MESH:D013733 Testicular Diseases pyrazole 4.696499806
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7712697716
MESH:D013964 Thyroid Neoplasms decitabine 11.4317967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 11.437505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 11.431399818
MESH:D013978 Tibial Fractures Estradiol 4.5619048282
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 4.9617053015
MESH:D001749 Urinary Bladder Neoplasms decitabine 4.9617616700 19087683
MESH:D014581 Urticaria Acetaminophen 2.8510982225
MESH:D014604 Uveal Neoplasms decitabine 4.7817785578
MESH:D014605 Uveitis Cyclosporine 3.851336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4712125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1215886252
MESH:D015430 Weight Gain Dietary Fats 3.6216723640
MESH:D014985 Xerophthalmia Cyclosporine 4.3117120751
Pathway ID Pathway Name
KEGG:04910 Insulin signaling pathway
REACT:474 Metabolism of carbohydrates
KEGG:00500 Starch and sucrose metabolism
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA29085
    • No data
    No data
    Releated drug ID Related drug Name
    PA450379mercaptopurine
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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