Annotation Detail for RHOD
Basic Information
Top
| Pathway ID | Pathway Name |
|---|
| hsa04360 | Axon guidance |
| Pathway ID | Pathway Name |
|---|
| Signaling by Rho GTPases |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of RHOD mRNA | affects expression | 21346803
|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of RHOD mRNA | affects expression | 21346803
|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of RHOD mRNA | affects expression | 17562736
|
| D001280 |
Atrazine |
Atrazine results in increased expression of RHOD mRNA | increases expression | 18585445
|
| D020122 |
tert-Butylhydroperoxide |
tert-Butylhydroperoxide results in decreased expression of RHOD mRNA | decreases expression | 15336504
|
| C479799 |
(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide |
(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide results in decreased expression of RHOD mRNA | decreases expression | 15528975
|
| C045651 |
epigallocatechin gallate |
epigallocatechin gallate results in decreased expression of RHOD mRNA | decreases expression | 18851785
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000382 |
Agricultural Workers' Diseases |
|
Atrazine |
4.62 | 11874814 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.29 | 10982225 |
| MESH:D001249 |
Asthma |
|
epigallocatechin gallate |
3.45 | 16516891 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D001327 |
Autoimmune Diseases |
|
epigallocatechin gallate |
5.42 | 19761891 |
| MESH:D001943 |
Breast Neoplasms |
|
(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide |
4.01 | 15528975 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
4.71 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
4.71 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
4.71 | 3084413 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.73 | 10977129 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
2.95 | 6135515 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
12.12 | 18551238 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
12.12 | 18551238 |
| MESH:D003924 |
Diabetes Mellitus, Type 2 |
|
epigallocatechin gallate |
3.33 | 16988119 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
6.58 | 21346803 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
6.58 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
6.58 | 18713872 19370779 12540782 11287661 19923254 16177239 10663392 12958197 2444490 17562736 19739265 10915739 11739529 14986274 12594235 16393943 14550746 10774834 11529661 11834606 19164858 16227642 12153990 15968718 15619225 12392966 14725611 19085960 16781746 19416960 11743745 16485898 18071297 11461765 16081117 12705907 17522070 11421492 19420014 17906064 16109766 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.54 | 19426721 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.12 | 16983495 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.92 | 16870215 |
| MESH:D007248 |
Infertility, Male |
|
Atrazine |
3.88 | 12948887 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.34 | 15629191 12587719 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
8.15 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
8.15 | 16705839 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
epigallocatechin gallate |
2.85 | 17481882 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.68 | 16611625 12969438 11587558 19014921 12587719 19784758 19460945 16610002 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.50 | 17185352 16871587 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
2.23 | 7678174 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.70 | 6135515 2876784 2876786 |
| MESH:D008175 |
Lung Neoplasms |
|
(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide |
3.57 | 15528975 |
| MESH:D008545 |
Melanoma |
|
epigallocatechin gallate |
3.02 | 17992120 11746506 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
3.93 | 19513568 |
| MESH:D008654 |
Mesothelioma |
|
Atrazine |
3.62 | 1916698 |
| MESH:D009134 |
Muscular Atrophy, Spinal |
|
epigallocatechin gallate |
5.89 | 17962980 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
11.70 | 18551238 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
11.70 | 18551238 7678174 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.10 | 18514411 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
9.78 | 12819281 16049721 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
9.78 | 16049721 |
| MESH:D010051 |
Ovarian Neoplasms |
|
(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide |
4.18 | 15528975 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.62 | 16870215 |
| MESH:D010300 |
Parkinson Disease |
|
Atrazine |
3.36 | 17218051 |
| MESH:D012135 |
Respiratory Sounds |
|
Atrazine |
4.87 | 11874814 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
6.47 | 18551238 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
6.47 | 18551238 |
| MESH:D012878 |
Skin Neoplasms |
|
tert-Butylhydroperoxide |
2.80 | 8532709 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
5.32 | 16049721 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
5.32 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
13.35 | 10091137 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
13.35 | 10091137 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.28 | 10982225 |
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