Annotation Detail for SLC39A2
Basic Information
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| Gene Symbol: | SLC39A2 ( 6A1,Eti-1,MGC119190,ZIP-2,ZIP2,hZIP2 ) |
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| Gene Full Name: | solute carrier family 39 (zinc transporter), member 2 |
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| Band: | 14q11.2 |
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| Quick Links | Entrez ID:29986; OMIM: 612166; Uniprot ID:S39A2_HUMAN; ENSEMBL ID: ENSG00000165794; HGNC ID: 17127 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| Transmembrane transport of small molecules |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of SLC39A2 mRNA | affects expression | 17562736
|
| D014810 |
Vitamin E |
Vitamin E results in increased expression of SLC39A2 mRNA | increases expression | 19244175
|
| D015032 |
Zinc |
SLC39A2 protein results in increased transport of Zinc | increases transport | 18326752
|
| D015032 |
Zinc |
Zinc results in increased expression of SLC39A2 mRNA | increases expression | 17028381
|
| D015032 |
Zinc |
SLC39A2 protein results in increased uptake of Zinc | increases uptake | 17126599
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000169 |
Acrodermatitis |
|
Zinc |
6.15 | 17190629 16889938 17202136 |
| MESH:D000544 |
Alzheimer Disease |
|
Zinc |
2.82 | 17119284 16325427 16410023 16580781 |
| MESH:D000755 |
Anemia, Sickle Cell |
|
Zinc |
5.49 | 16916123 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.71 | 10982225 |
| MESH:D001249 |
Asthma |
|
Zinc |
3.05 | 17085522 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.39 | 18445737 |
| MESH:D001930 |
Brain Injuries |
|
Zinc |
5.34 | 17109824 |
| MESH:D002252 |
Carbon Tetrachloride Poisoning |
|
Vitamin E |
4.58 | 16050911 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
1.41 | 3084413 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Zinc |
2.99 | 16543248 |
| MESH:D002318 |
Cardiovascular Diseases |
|
Zinc |
3.95 | 16936243 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.81 | 10977129 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Vitamin E |
3.01 | 19769572 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Zinc |
3.01 | 19302082 |
| MESH:D003920 |
Diabetes Mellitus |
|
Zinc |
4.62 | 16479319 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
1.68 | 12540782 19923254 17906064 16109766 10915739 2444490 11743745 17562736 11529661 12153990 16227642 12392966 19739265 17522070 11461765 19085960 14725611 12958197 11834606 16485898 11287661 19370779 14986274 10774834 18071297 11421492 11739529 16081117 14550746 12594235 16781746 16393943 19416960 19164858 12705907 16177239 18713872 15619225 19420014 15968718 10663392 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.96 | 19426721 |
| MESH:C538011 |
Eales disease |
|
Vitamin E |
5.57 | 9068938 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Zinc |
2.94 | 16543248 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
14.28 | 16983495 |
| MESH:D005756 |
Gastritis |
|
Zinc |
14.28 | 17241300 |
| MESH:D006130 |
Growth Disorders |
|
Zinc |
4.22 | 17217573 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Vitamin E |
3.18 | 16080930 |
| MESH:D006333 |
Heart Failure |
|
Zinc |
3.85 | 17162251 |
| MESH:D006335 |
Heart Injuries |
|
Zinc |
6.64 | 17074742 |
| MESH:D016481 |
Helicobacter Infections |
|
Zinc |
5.06 | 17241300 |
| MESH:D006527 |
Hepatolenticular Degeneration |
|
Zinc |
5.34 | 17276780 |
| MESH:D006548 |
Hernia, Diaphragmatic |
|
Vitamin E |
2.82 | 16863852 16490937 |
| MESH:D019584 |
Hot Flashes |
|
Vitamin E |
4.84 | 14716179 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
3.06 | 16870215 |
| MESH:D007251 |
Influenza, Human |
|
Vitamin E |
5.08 | 16624496 |
| MESH:D007511 |
Ischemia |
|
Zinc |
5.28 | 16584753 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
11.48 | 12587719 15629191 |
| MESH:D007674 |
Kidney Diseases |
|
Vitamin E |
11.48 | 12488133 |
| MESH:D007674 |
Kidney Diseases |
|
Zinc |
11.48 | 16960431 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Zinc |
4.90 | 16518626 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Vitamin E |
1.91 | 16169303 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.71 | 12969438 11587558 19014921 12587719 19460945 16611625 19784758 16610002 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.68 | 16871587 17185352 |
| MESH:D008171 |
Lung Diseases |
|
Vitamin E |
3.45 | 16863852 |
| MESH:D008175 |
Lung Neoplasms |
|
Vitamin E |
1.90 | 11062179 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Zinc |
3.56 | 12773700 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.22 | 19513568 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.26 | 18514411 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.77 | 16870215 |
| MESH:D011225 |
Pre-Eclampsia |
|
Zinc |
4.52 | 17114810 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Vitamin E |
3.41 | 15084515 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Zinc |
3.41 | 16606632 16517595 12429649 16700911 |
| MESH:D012162 |
Retinal Degeneration |
|
Zinc |
4.45 | 16584753 |
| MESH:D012871 |
Skin Diseases |
|
Vitamin E |
2.52 | 18709164 |
| MESH:D020521 |
Stroke |
|
Vitamin E |
3.88 | 16517955 |
| MESH:D014062 |
Tongue Neoplasms |
|
Zinc |
4.85 | 16543248 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.50 | 10982225 |
| Pathway ID |
Pathway Name |
|---|
| REACT:15518 |
Transmembrane transport of small molecules |
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