Annotation Detail for PACSIN1
Basic Information
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| Pathway ID | Pathway Name |
|---|
| P00029 | Huntington disease |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of PACSIN1 mRNA | affects expression | 16483693
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PACSIN1 mRNA | affects binding|increases activity|increases expression | 19710929
|
| C025643 |
vinclozolin |
vinclozolin affects the expression of PACSIN1 mRNA | affects expression | 19015723
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
4.30 | 18287403 |
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.64 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.22 | 16434500 |
| MESH:D001008 |
Anxiety Disorders |
|
vinclozolin |
4.00 | 19015723 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.63 | 19483382 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.15 | 19176532 |
| MESH:D003456 |
Cryptorchidism |
|
vinclozolin |
4.93 | 14966744 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.59 | 18249437 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.96 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.25 | 19236843 20131406 |
| MESH:D030342 |
Genetic Diseases, Inborn |
|
vinclozolin |
5.68 | 16973722 |
| MESH:D005832 |
Genital Diseases, Male |
|
vinclozolin |
6.17 | 16417039 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.78 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.64 | 18467677 19772884 16221962 19176532 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.63 | 20558911 |
| MESH:D007248 |
Infertility, Male |
|
vinclozolin |
3.32 | 16467254 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.90 | 16306350 |
| MESH:D007984 |
Leydig Cell Tumor |
|
vinclozolin |
5.47 | 16417039 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.94 | 20007298 15890375 16377806 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.16 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.29 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.29 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.12 | 17405874 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.89 | 20558911 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
vinclozolin |
4.64 | 19015723 18220299 18042343 |
| MESH:D011469 |
Prostatic Diseases |
|
vinclozolin |
5.68 | 18220299 |
| MESH:D011472 |
Prostatitis |
|
vinclozolin |
5.68 | 18629315 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.56 | 19058328 |
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