AutismKB 2.0

Annotation Detail for BAZ2B


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Basic Information Top
Gene Symbol:BAZ2B ( DKFZp434H071,DKFZp762I0516,FLJ45644,WALp4 )
Gene Full Name: bromodomain adjacent to zinc finger domain, 2B
Band: 2q24.2
Quick LinksEntrez ID:29994; OMIM: 605683; Uniprot ID:BAZ2B_HUMAN; ENSEMBL ID: ENSG00000123636; HGNC ID: 963
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of BAZ2B mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of BAZ2B mRNAaffects expression 17562736
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of BAZ2B mRNAdecreases expression 20106945
D003010 Clorgyline Clorgyline results in increased expression of BAZ2B mRNAincreases expression 19691856
C017947 sodium arsenite sodium arsenite results in increased expression of BAZ2B mRNAincreases expression 17879257
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0520127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.846695378
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 5.3115276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.5117306315 16712894
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.5619183758
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0020146248 17474063
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.7916705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.793084413
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 4.7915276417 16507464 17306315
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.8820419170
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.8818572023
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 7.536135515
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 7.5320056578 19524636
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.5018551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 3.9921346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.9912153990 16227642 12705907 11834606 14550746 14986274 10915739 19739265 10663392 12958197 17906064 16781746 12540782 14725611 11529661 11421492 11287661 19416960 18713872 17522070 19164858 18071297 11743745 11461765 11739529 19420014 10774834 12392966 19370779 19923254 17562736 2444490 16485898 16081117 15968718 19085960 15619225 12594235 16109766 16177239 16393943
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0716530937
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D005833 Genital Neoplasms, Female sodium arsenite 5.2216452187
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8220471113
MESH:D006689 Hodgkin Disease sodium arsenite 3.4712676792
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D007248 Infertility, Male sodium arsenite 3.2115346721 12646999
MESH:D007674 Kidney Diseases Acetaminophen 6.5812587719 15629191
MESH:D007674 Kidney Diseases sodium arsenite 6.5820008137
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.2816705839
MESH:D008107 Liver Diseases Acetaminophen 1.6919784758 12587719 11587558 16611625 19014921 16610002 12969438 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5817185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 8.107678174
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 8.1021137059 20195826
MESH:D008113 Liver Neoplasms sodium arsenite 8.1015276417 16712894
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.742876784 6135515 2876786
MESH:D008171 Lung Diseases sodium arsenite 3.4019095001
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.5020064080 17053015 20869020 20135361 18816296 20464547 18569708 18520028 6695378
MESH:D008175 Lung Neoplasms sodium arsenite 2.5016712894 19931552 15276417 17077188 17306315
MESH:D008545 Melanoma sodium arsenite 2.0719082730 16487513
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4616381670
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.407678174 18551238
MESH:D009369 Neoplasms Benzo(a)pyrene 5.5311141357
MESH:D009369 Neoplasms sodium arsenite 5.5311559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 4.1520056578
MESH:D009436 Neural Tube Defects sodium arsenite 3.3612854658
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.7816049721
MESH:D010051 Ovarian Neoplasms sodium arsenite 2.5215276417 17306315
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.6317292933
MESH:D011471 Prostatic Neoplasms Clorgyline 2.6319691856
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.6316039940
MESH:D012640 Seizures 2,6-dinitrotoluene 2.7618551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 6.1919755658 10029692
MESH:D012878 Skin Neoplasms sodium arsenite 6.1918572023 19524636
MESH:D016135 Spinal Dysraphism sodium arsenite 4.0712854658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 8.9716049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.9717053015
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.9711723127 17306315 16712894 16452187
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.8610091137
MESH:D014581 Urticaria Acetaminophen 3.3810982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 4.1111813266
MESH:D014652 Vascular Diseases sodium arsenite 4.9617056641
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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