AutismKB 2.0

Annotation Detail for H1F0


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Basic Information Top
Gene Symbol:H1F0 ( H10,H1FV,MGC5241 )
Gene Full Name: H1 histone family, member 0
Band: 22q13.1
Quick LinksEntrez ID:3005; OMIM: 142708; Uniprot ID:H10_HUMAN; ENSEMBL ID: ENSG00000189060; HGNC ID: 4714
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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No data
Pathway IDPathway Name
Apoptosis
No data
No data
Pathway IDPathway Name
500275Activation of DNA fragmentation factor
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C010914 2,4-diaminotoluene 2,4-diaminotoluene results in decreased expression of H1F0 mRNAdecreases expression 20713471
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of H1F0 mRNAaffects expression 21346803
C430898 AGN 194204 AGN 194204 results in increased expression of H1F0 mRNAincreases expression 16339527
D000643 Ammonium Chloride Ammonium Chloride affects the expression of H1F0 mRNAaffects expression 16483693
C015001 arsenite arsenite results in decreased expression of H1F0 mRNAdecreases expression 18929588
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of H1F0 mRNAincreases expression 18687144
D001374 Azacitidine Azacitidine results in increased expression of H1F0 proteinincreases expression 16006241
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of H1F0 mRNAdecreases expression 19150397
20018196
20382639
D002087 Butyrates Butyrates results in increased expression of H1F0 proteinincreases expression 16006241
D016572 Cyclosporine Cyclosporine results in increased expression of H1F0 mRNAincreases expression 20106945
C014347 decitabine [decitabine co-treated with vorinostat] affects the expression of H1F0 mRNAaffects cotreatment|affects expression 17330099
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of H1F0 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of H1F0 mRNAaffects cotreatment|increases expression 17942748
C013598 methoxyacetic acid methoxyacetic acid results in increased expression of H1F0 mRNAincreases expression 18199887
D008767 Methylmercury Compounds Methylmercury Compounds results in increased expression of H1F0 mRNAincreases expression 16966085
C008493 methylselenic acid methylselenic acid affects the expression of H1F0 mRNAaffects expression 14617803
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in decreased expression of H1F0 mRNAdecreases expression 17616710
D010269 Paraquat Paraquat results in decreased expression of H1F0 mRNAdecreases expression 17275934
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of H1F0 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of H1F0 mRNAincreases expression 18445702
C045950 propiconazole propiconazole results in decreased expression of H1F0 mRNAdecreases expression 19363144
C487081 PXD101 PXD101 results in increased expression of H1F0 mRNAincreases expression 19606018
D011794 Quercetin Quercetin affects the expression of H1F0 mRNAaffects expression 18178720
C017947 sodium arsenite sodium arsenite results in decreased expression of H1F0 mRNAdecreases expression 16014739
D018038 Sodium Selenite Sodium Selenite results in decreased expression of H1F0 mRNAdecreases expression 18175754
D013629 Tamoxifen Tamoxifen affects the expression of H1F0 mRNAaffects expression 14699072
D013629 Tamoxifen Tamoxifen affects the expression of H1F0 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of H1F0 mRNAaffects cotreatment|increases expression 17942748
D014212 Tretinoin Tretinoin results in increased expression of H1F0 proteinincreases expression 16006241
C032910 triadimefon triadimefon results in decreased expression of H1F0 mRNAdecreases expression 19363144
C012589 trichostatin A trichostatin A results in increased expression of H1F0 mRNAincreases expression 19606018
C111237 vorinostat [decitabine co-treated with vorinostat] affects the expression of H1F0 mRNAaffects cotreatment|affects expression 17330099
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.2814745880
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 12.927525203
MESH:D000014 Abnormalities, Drug-Induced methoxyacetic acid 12.921761404 1761407 15959878 3652986 12805644
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 12.9211752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.3018287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6817505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.8818653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.7514692618
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.0216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.0216835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.4315276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.6416712894 17306315
MESH:D000382 Agricultural Workers' Diseases Paraquat 3.5111874814
MESH:D000505 Alopecia Tretinoin 3.4115955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7211748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.0017084956
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.6715885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.6716412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2016292516
MESH:D001249 Asthma Tretinoin 2.2716456186
MESH:D001260 Ataxia Telangiectasia Quercetin 4.7115336622
MESH:D001327 Autoimmune Diseases Quercetin 4.1519761891
MESH:D001471 Barrett Esophagus Tretinoin 4.1516935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.9119483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.9112125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 13.9116206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6015746008
MESH:D001943 Breast Neoplasms 2,4-diaminotoluene 3.6011921183
MESH:D001943 Breast Neoplasms decitabine 3.6018320071 19208741
MESH:D001943 Breast Neoplasms Quercetin 3.6018628248
MESH:D001943 Breast Neoplasms Tamoxifen 3.6019244106 16273361 19103187 19410462 11161223 18425577 18815881 21138602 15668708 20859285 20135344 19059307 17261762 16873071 19200415 20390343 19189212 19066611 18351453 16818667 19115204 19289846 19142967 17242785 19221464 17049068 17893378 18997820 18629630 18821012 19189210 19487384 21152245 17440819 15565566 20065188 19011961 20005174 19155303 18984771 16202921 19288272 20544844 19084267 18855134
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.6020435547
MESH:D001943 Breast Neoplasms Tretinoin 3.6016166294 16443354 16873071
MESH:D001943 Breast Neoplasms vorinostat 3.6016144943
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.3316813970
MESH:D002105 Cadmium Poisoning Quercetin 5.2816962696
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5916835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.2519066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.8916168501
MESH:D006528 Carcinoma, Hepatocellular Quercetin 6.2412508355 19519916
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 6.2417306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 6.2416924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 6.241917145
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.7017234771
MESH:D002294 Carcinoma, Squamous Cell decitabine 7.1219215824
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 7.1218572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 7.1216096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.3917572228
MESH:D006332 Cardiomegaly Quercetin 6.3219794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.3218670907 16120746 18850075
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 7.1014694615
MESH:D002386 Cataract Tretinoin 7.1017460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.1320889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.1312371664
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 10.1320056578 19524636
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.3316129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.9416835633
MESH:D002779 Cholestasis Cyclosporine 12.2319486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.2315861022 17681005 17110522 16105132 17333356 11677210 16919318
MESH:D002779 Cholestasis pirinixic acid 12.2319176532
MESH:D002822 Choriocarcinoma Tretinoin 4.8916461808
MESH:D019457 Chromosome Breakage Sodium Selenite 4.4915894690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 9.2715668235 15340226 16354765 8697196 12621046
MESH:D002972 Cleft Palate Tretinoin 9.279407595
MESH:D002972 Cleft Palate triadimefon 9.2716781842
MESH:D003092 Colitis Tretinoin 3.4517035595
MESH:D003110 Colonic Neoplasms arsenite 7.9515037631
MESH:D003110 Colonic Neoplasms Butyrates 7.9515936596
MESH:D003110 Colonic Neoplasms decitabine 7.9517616700
MESH:D003110 Colonic Neoplasms Quercetin 7.9519056647 17191121 16640504 15741050 17148506 11134977 19440933
MESH:D015179 Colorectal Neoplasms Azacitidine 3.4719934284
MESH:D015179 Colorectal Neoplasms decitabine 3.4718981723
MESH:D015179 Colorectal Neoplasms Quercetin 3.4718852136 18095365
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 8.4615095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.4614669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7210048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.729664655 17551590 9224671 16925845 8800419 10589399 9125849 9142499 9211117 14991402
MESH:D019465 Craniofacial Abnormalities triadimefon 3.7215834900 16875885
MESH:D003704 Dementia Methylmercury Compounds 4.7616140633
MESH:D003711 Demyelinating Diseases Tamoxifen 4.1019031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3018249437
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.5616285004
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.5219496084
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6117107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.2619279558
MESH:D003967 Diarrhea vorinostat 4.2520479100
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 5.8321346803
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 5.8315131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 5.8320420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5711462148
MESH:D004487 Edema pirinixic acid 5.7712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.7711000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.0518230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 11.0518230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.1112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.1119031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 13.1419294695
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 13.1419294695
MESH:D016889 Endometrial Neoplasms Tamoxifen 6.8717893378 20544844 19155303 16202921
MESH:D016889 Endometrial Neoplasms Tretinoin 6.8716569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.8010568697 9294722
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.4020426865
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 4.4016510608 15150132 15878914 15623463 15264214 16805852 15547733 16704527 15547721
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.1911564622
MESH:D005124 Eye Abnormalities Tretinoin 8.199664655 16938888
MESH:D005221 Fatigue vorinostat 5.3320479100
MESH:D005234 Fatty Liver arsenite 22.1418296743
MESH:D005234 Fatty Liver Cyclosporine 22.1419224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 22.1415345470
MESH:D005234 Fatty Liver pirinixic acid 22.1420131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 22.1414986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0816709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2011858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.2614745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.9219069698
MESH:D005355 Fibrosis arsenite 24.9918296743
MESH:D005355 Fibrosis Cyclosporine 24.9912639820 12168785
MESH:D005355 Fibrosis Quercetin 24.9919474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 24.9920067830
MESH:D005355 Fibrosis Tretinoin 24.9917994277
MESH:D005532 Foot Deformities, Congenital methoxyacetic acid 5.473652986
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.4216452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.958708960
MESH:D005909 Glioblastoma Quercetin 11.0319804834
MESH:D005909 Glioblastoma Tretinoin 11.0317312396
MESH:D005909 Glioblastoma trichostatin A 11.0318801729
MESH:D005910 Glioma Quercetin 2.9517643826
MESH:D005911 Gliosis Paraquat 4.9011124998
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3310696789
MESH:D006258 Head and Neck Neoplasms decitabine 7.2519215824
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.2516096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.8916084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.0811294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 6.0814991402 9664655
MESH:D006333 Heart Failure pirinixic acid 2.3820558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.1615720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1011000095
MESH:D006529 Hepatomegaly pirinixic acid 18.6419772884 19176532 16221962 18467677
MESH:D006529 Hepatomegaly propiconazole 18.6417178689 17178688
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 18.6415340226 16120746 12621046
MESH:D006529 Hepatomegaly triadimefon 18.6417178688 17178689
MESH:D006689 Hodgkin Disease sodium arsenite 2.9412676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.7818606429 15340226 8697196 16959395 16354765
MESH:D006930 Hyperalgesia Tretinoin 3.0116870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.3116778211
MESH:D006943 Hyperglycemia pirinixic acid 8.4920558911
MESH:D006943 Hyperglycemia Quercetin 8.4911834736 18262572
MESH:D006973 Hypertension Cyclosporine 7.9810903974
MESH:D006973 Hypertension Quercetin 7.9818356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.9818850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.5516569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2212013081
MESH:D007248 Infertility, Male decitabine 14.6317581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 14.6317937319
MESH:D007248 Infertility, Male Paraquat 14.634850670
MESH:D007248 Infertility, Male sodium arsenite 14.6312646999 15346721
MESH:D007249 Inflammation Tamoxifen 4.4419457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.4412200463 12878042
MESH:D007251 Influenza, Human Quercetin 4.2416624496
MESH:D007333 Insulin Resistance pirinixic acid 6.7516306350
MESH:D007333 Insulin Resistance Sodium Selenite 6.7514714311
MESH:D007410 Intestinal Diseases Tretinoin 3.5117994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 15.8916580747
MESH:D007569 Jaw Abnormalities Tretinoin 15.8915992940 17551590
MESH:D007569 Jaw Abnormalities triadimefon 15.8915992940 15834900
MESH:D007627 Keloid Quercetin 4.7017086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.1715604871
MESH:D007674 Kidney Diseases Cyclosporine 9.258314463 10903974 18776723
MESH:D007674 Kidney Diseases Quercetin 9.2516962696
MESH:D007674 Kidney Diseases sodium arsenite 9.2520008137
MESH:D007680 Kidney Neoplasms Cyclosporine 6.6012371664
MESH:D007680 Kidney Neoplasms Tamoxifen 6.6018625569
MESH:D007938 Leukemia Azacitidine 13.9419148494
MESH:D007938 Leukemia decitabine 13.9418980019 19235587
MESH:D007938 Leukemia Quercetin 13.9417468513
MESH:D007938 Leukemia Tretinoin 13.9417143497
MESH:D007951 Leukemia, Myeloid Azacitidine 14.7519077051
MESH:D007951 Leukemia, Myeloid decitabine 14.7519117987 18454857 17236224
MESH:D007951 Leukemia, Myeloid Tretinoin 14.7519285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute marker/mechanism 17330099
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 8.4117596541 18720364
MESH:D015470 Leukemia, Myeloid, Acute decitabine 8.4117679729 18206229 18460780 19387464 19010910 18704418
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 8.4117596541 16294345 19850784
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 8.4118206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.1918055864
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 4.9519299654
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.9812679006 17712046 16140955 17361223 17368321 19035177 16935935 19075265 17301526 9834237 19029980 16788101 17506722 17294898 19225113 17649720 16331271 17107899 17217047 16891316 16766008 17339181 15748426 16823087 19642359
MESH:D017880 Limb Deformities, Congenital methoxyacetic acid 8.0415959878 12805644
MESH:D017880 Limb Deformities, Congenital Tretinoin 8.049224671
MESH:D008064 Lipidoses Tamoxifen 2.9717567588 15342952
MESH:D008103 Liver Cirrhosis arsenite 3.2818296743
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.3615474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 6.3612741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 6.3618564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.3612878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.3616248980 18397230
MESH:D008107 Liver Diseases propiconazole 4.6719363144
MESH:D008107 Liver Diseases triadimefon 4.6719363144
MESH:D008113 Liver Neoplasms pirinixic acid 20.3415890375 20007298 16377806
MESH:D008113 Liver Neoplasms propiconazole 20.3419028983
MESH:D008113 Liver Neoplasms Quercetin 20.3418980244
MESH:D008113 Liver Neoplasms sodium arsenite 20.3416712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 20.3416684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 20.3416984957
MESH:D008113 Liver Neoplasms triadimefon 20.3419028983
MESH:D008114 Liver Neoplasms, Experimental propiconazole 12.9017178689
MESH:D008114 Liver Neoplasms, Experimental Quercetin 12.9019519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 12.9012151625
MESH:D008114 Liver Neoplasms, Experimental triadimefon 12.9017178689
MESH:D008171 Lung Diseases sodium arsenite 3.0019095001
MESH:D055370 Lung Injury Asbestos, Crocidolite 3.7717365036
MESH:D008175 Lung Neoplasms arsenite 8.1116809336
MESH:D008175 Lung Neoplasms Azacitidine 8.1121224363
MESH:D008175 Lung Neoplasms Quercetin 8.1116280456
MESH:D008175 Lung Neoplasms sodium arsenite 8.1115276417 17077188 16712894 19931552 17306315
MESH:D008175 Lung Neoplasms Tamoxifen 8.1118625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.1111884234 19555203
MESH:D008223 Lymphoma decitabine 3.2319470736
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 3.8214737004
MESH:D016410 Lymphoma, T-Cell, Cutaneous vorinostat 5.4320479100
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.5019428831
MESH:D008325 Mammary Neoplasms, Experimental 2,4-diaminotoluene 5.7911921183
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 5.7911731420 19196722 14580682 19196723 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 4.2819453300
MESH:D008527 Medulloblastoma Tretinoin 2.6817453147
MESH:D008545 Melanoma decitabine 9.2716505122 17785578
MESH:D008545 Melanoma sodium arsenite 9.2716487513 19082730
MESH:D008545 Melanoma Tamoxifen 9.2712393984 19393235
MESH:D008545 Melanoma Tretinoin 9.2716752155
MESH:D008545 Melanoma trichostatin A 9.2716505122
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.9215990972
MESH:D008569 Memory Disorders Methylmercury Compounds 4.6618436314
MESH:D008591 Meningomyelocele Tretinoin 4.1716940565
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.0816966607 18303189 16166281
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5216801185
MESH:D009006 Monosomy Azacitidine 5.8119299654
MESH:D009069 Movement Disorders Methylmercury Compounds 5.0818436314
MESH:D009101 Multiple Myeloma Azacitidine 11.2819549372 18443271
MESH:D009101 Multiple Myeloma decitabine 11.2818172295
MESH:D009101 Multiple Myeloma trichostatin A 11.2818172295
MESH:D009135 Muscular Diseases pirinixic acid 3.2516239165
MESH:D009190 Myelodysplastic Syndromes Azacitidine 11.5919805378 17596541 18720364 17611569
MESH:D009190 Myelodysplastic Syndromes decitabine 11.5919157545 18608210 19010910 16882708
MESH:D009190 Myelodysplastic Syndromes Tretinoin 11.5917596541
MESH:D009203 Myocardial Infarction pirinixic acid 5.3619151258
MESH:D009203 Myocardial Infarction Quercetin 5.3619595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8112213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.7816411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 7.7819207477
MESH:D009325 Nausea vorinostat 5.2620479100
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.4419393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4319410462
MESH:D009369 Neoplasms decitabine 14.3417925555 19116145 19470736
MESH:D009369 Neoplasms pirinixic acid 14.3417405874
MESH:D009369 Neoplasms Quercetin 14.3415185748
MESH:D009369 Neoplasms sodium arsenite 14.3411559025
MESH:D009369 Neoplasms Tretinoin 14.3416946489 16594593
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.4120056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.7319200415 19189210 19196722
MESH:D009389 Neovascularization, Pathologic arsenite 4.1515738583
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.1717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.0619348381 18481113
MESH:D009410 Nerve Degeneration Paraquat 3.5216893418
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.6814600291
MESH:D009421 Nervous System Malformations Tretinoin 8.689125849
MESH:D009436 Neural Tube Defects sodium arsenite 6.7512854658
MESH:D009436 Neural Tube Defects Tretinoin 6.759142499
MESH:D020078 Neurogenic Inflammation Quercetin 4.1217929310
MESH:D009765 Obesity pirinixic acid 1.7520558911
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 3.8714694615
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 3.9819495926
MESH:D010051 Ovarian Neoplasms decitabine 14.0919331143 19259094
MESH:D010051 Ovarian Neoplasms Quercetin 14.0919005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 14.0915276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 14.0916936753
MESH:D010051 Ovarian Neoplasms trichostatin A 14.0919331143
MESH:D010146 Pain Tretinoin 2.7016870215
MESH:D010190 Pancreatic Neoplasms decitabine 11.6019294695
MESH:D010190 Pancreatic Neoplasms Quercetin 11.6016965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 11.6015976015
MESH:D010190 Pancreatic Neoplasms trichostatin A 11.6019294695
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4411578682
MESH:D010300 Parkinson Disease Paraquat 2.7212911755 11124998 15451049 15824117 11445065 16140633 16510128 11181820
MESH:D010302 Parkinson Disease, Secondary Paraquat 4.1716190885
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9812520081
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.6310923243
MESH:D011014 Pneumonia Paraquat 4.1912504350
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3118163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.3712371664
MESH:D011230 Precancerous Conditions Quercetin 8.3719056647
MESH:D011297 Prenatal Exposure Delayed Effects Methylmercury Compounds 9.0118436314
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.0111896295 11399792 11222880 11118676
MESH:D055728 Primary Myelofibrosis decitabine 11.5717616702
MESH:D055728 Primary Myelofibrosis trichostatin A 11.5717616702
MESH:D011471 Prostatic Neoplasms AGN 194204 2.8616000583
MESH:D011471 Prostatic Neoplasms Azacitidine 2.8618324645
MESH:D011471 Prostatic Neoplasms methylselenic acid 2.8616205645
MESH:D011471 Prostatic Neoplasms Quercetin 2.8614715546 17292933
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.8616039940
MESH:D011471 Prostatic Neoplasms Sodium Selenite 2.8618760546
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.8615067354
MESH:D011471 Prostatic Neoplasms trichostatin A 2.8619789329 18798265
MESH:D011471 Prostatic Neoplasms vorinostat 2.8617218635
MESH:D011507 Proteinuria Tretinoin 3.3616636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.0515861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.1416882103
MESH:D011625 Pterygium Tretinoin 4.5316723453
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 5.5617322281 17365031 15814490 17975199
MESH:D011658 Pulmonary Fibrosis Paraquat 5.5617997886 16324872
MESH:D015427 Reperfusion Injury pirinixic acid 2.2619058328
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 3.6611700416
MESH:D012135 Respiratory Sounds Paraquat 3.8011874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5918990726
MESH:D012162 Retinal Degeneration Paraquat 3.6716458197
MESH:D012208 Rhabdomyosarcoma decitabine 10.1419155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 10.1416116481 16283617
MESH:D012554 Schistosomiasis japonica Quercetin 5.2816862918
MESH:D012878 Skin Neoplasms sodium arsenite 8.7119524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.7116192470
MESH:D012878 Skin Neoplasms Tretinoin 8.7116467112
MESH:D013088 Spermatocele Ethinyl Estradiol 10.6716709447
MESH:D013088 Spermatocele Tamoxifen 10.6716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.7819457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.6012854658
MESH:D013274 Stomach Neoplasms decitabine 3.3319037991
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 3.3312958204 17575124
MESH:D013274 Stomach Neoplasms Tretinoin 3.3317261132
MESH:D013576 Syndactyly methoxyacetic acid 5.381761404 1761407
MESH:D013733 Testicular Diseases methoxyacetic acid 5.076499806 18486176
MESH:D013921 Thrombocytopenia vorinostat 4.7420479100
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9315669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6412697716
MESH:D013964 Thyroid Neoplasms Butyrates 15.6017967635
MESH:D013964 Thyroid Neoplasms decitabine 15.6017967635
MESH:D013964 Thyroid Neoplasms Tretinoin 15.6017045167 16026305
MESH:D013964 Thyroid Neoplasms triadimefon 15.6017178689
MESH:D014062 Tongue Neoplasms Tretinoin 3.5616051514
MESH:D014376 Tuberculosis Tretinoin 3.0716040207
MESH:D001749 Urinary Bladder Neoplasms decitabine 11.1019087683 17616700
MESH:D001749 Urinary Bladder Neoplasms Quercetin 11.1016720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 11.1011723127 16712894 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 11.108653321 16712894 17572228
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 8.6511813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.6516129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.0514692618
MESH:D014604 Uveal Neoplasms decitabine 11.9417785578
MESH:D014604 Uveal Neoplasms Tretinoin 11.9416752155
MESH:D014605 Uveitis Cyclosporine 3.721336536
MESH:D014652 Vascular Diseases sodium arsenite 4.1617056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3312125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3015869587 14671159
MESH:D014820 Vitiligo Tretinoin 3.8116761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9815886252
MESH:D009396 Wilms Tumor Tretinoin 3.7516287080
MESH:D014985 Xerophthalmia Cyclosporine 4.1717120751
Pathway ID Pathway Name
REACT:578 Apoptosis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA29092
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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