AutismKB 2.0

Annotation Detail for SLC40A1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SLC40A1 ( FPN1,HFE4,IREG1,MST079,MTP1,SLC11A3 )
Gene Full Name: solute carrier family 40 (iron-regulated transporter), member 1
Band: 2q32.2
Quick LinksEntrez ID:30061; OMIM: 604653; Uniprot ID:S40A1_HUMAN; ENSEMBL ID: ENSG00000138449; HGNC ID: 10909
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Transmembrane transport of small molecules
No data
No data
Pathway IDPathway Name
500353Metal ion SLC transporters
Related Diseases/Disorders Top
Desease IDDesease Name
Inherited disorders of ion transport and metabolism
H00211Hemochromatosis
Genetic disorders
No data
Desease Name
cystinuria
haemochromatosis
METABOLIC
No data
Desease Name
Hemochromatosis, type 4
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of SLC40A1 mRNAincreases expression 19933214
C018855 2-tert-butylhydroquinone 2-tert-butylhydroquinone results in increased expression of SLC40A1 mRNAincreases expression 16014739
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of SLC40A1 mRNAincreases expression 18648102
C105260 4-tert-octylphenol 4-tert-octylphenol results in increased expression of SLC40A1 mRNAincreases expression 17011747
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of SLC40A1 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SLC40A1 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of SLC40A1 mRNAincreases expression 19128835
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in decreased expression of SLC40A1 mRNAdecreases expression 18687144
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of SLC40A1 mRNAincreases expression 20106945
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of SLC40A1 mRNAincreases expression 20127859
C006780 bisphenol A bisphenol A affects the expression of SLC40A1 mRNAaffects expression 20170705
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of SLC40A1 proteinincreases expression 17544377
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in decreased expression of SLC40A1 mRNAdecreases expression 18178546
D003300 Copper Copper affects the expression of SLC40A1 mRNAaffects expression 16614410
D003300 Copper Copper affects the expression of SLC40A1 proteinaffects expression 16614410
D016572 Cyclosporine Cyclosporine results in decreased expression of SLC40A1 mRNAdecreases expression 20106945
D019259 Lamivudine [Zidovudine co-treated with Lamivudine] results in increased expression of SLC40A1 mRNAaffects cotreatment|increases expression 18313992
D004040 Dietary Carbohydrates Dietary Carbohydrates results in increased expression of SLC40A1 mRNAincreases expression 17490981
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of SLC40A1 mRNAdecreases expression 19061943
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of SLC40A1 proteindecreases expression 19061943
D004052 Diethylnitrosamine Iron inhibits the reaction [Diethylnitrosamine results in decreased expression of SLC40A1 mRNA]decreases expression|decreases reaction 19061943
D004052 Diethylnitrosamine Iron inhibits the reaction [Diethylnitrosamine results in decreased expression of SLC40A1 protein]decreases expression|decreases reaction 19061943
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of SLC40A1 mRNAincreases expression 19638242
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of SLC40A1 mRNAincreases expression 17011747
D004958 Estradiol Estradiol results in increased expression of SLC40A1 mRNAincreases expression 16684588
D000431 Ethanol Ethanol results in increased expression of SLC40A1 proteinincreases expression 16737972
D000431 Ethanol HAMP protein inhibits the reaction [Ethanol results in increased expression of SLC40A1 protein]decreases reaction|increases expression 16737972
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SLC40A1 mRNAaffects expression 20170705
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SLC40A1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SLC40A1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SLC40A1 mRNAincreases expression 17108234
C020326 ferric nitrilotriacetate ferric nitrilotriacetate results in decreased expression of SLC40A1 mRNAdecreases expression 11925462
D005492 Folic Acid Folic Acid affects the expression of SLC40A1 mRNAaffects expression 17868486
D007501 Iron [HBB-B1 gene mutant form results in increased abundance of Iron] which results in increased expression of SLC40A1 mRNAincreases abundance|increases expression 17018382
D007501 Iron [HBB-B2 gene mutant form results in increased abundance of Iron] which results in increased expression of SLC40A1 mRNAincreases abundance|increases expression 17018382
D007501 Iron Iron inhibits the reaction [Diethylnitrosamine results in decreased expression of SLC40A1 mRNA]decreases expression|decreases reaction 19061943
D007501 Iron Iron inhibits the reaction [Diethylnitrosamine results in decreased expression of SLC40A1 protein]decreases expression|decreases reaction 19061943
D007501 Iron Iron results in increased expression of SLC40A1 mRNAincreases expression 16648237
16565419
D007501 Iron SLC40A1 protein affects the metabolism of Ironaffects metabolic processing 17194590
D007501 Iron SLC40A1 protein mutant form results in decreased export of Irondecreases export 16457665
D007501 Iron SLC40A1 protein mutant form results in increased export of Ironincreases export 16457665
D007501 Iron SLC40A1 protein results in increased export of Ironincreases export 16457665
D019266 Iron, Dietary Iron, Dietary affects the expression of SLC40A1 mRNAaffects expression 15637178
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of SLC40A1 mRNAdecreases expression 16648237
16565419
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of SLC40A1 mRNAincreases expression 17560707
D026023 Permethrin Permethrin results in decreased expression of SLC40A1 mRNAdecreases expression 19017407
D010615 Phenacetin Phenacetin results in increased expression of SLC40A1 mRNAincreases expression 17082564
C030299 phenylhydrazine phenylhydrazine results in increased expression of SLC40A1 mRNAincreases expression 17082564
C006253 pirinixic acid pirinixic acid results in decreased expression of SLC40A1 mRNAdecreases expression 18445702
D013629 Tamoxifen Tamoxifen affects the expression of SLC40A1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of SLC40A1 mRNAaffects binding|decreases expression 16214954
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SLC40A1 mRNAincreases expression 19933214
D014415 Tunicamycin Tunicamycin results in decreased expression of SLC40A1 mRNAdecreases expression 17127020
D015215 Zidovudine [Zidovudine co-treated with Lamivudine] results in increased expression of SLC40A1 mRNAaffects cotreatment|increases expression 18313992
D015032 Zinc Zinc results in decreased expression of SLC40A1 proteindecreases expression 16614402
D015032 Zinc Zinc results in increased expression of SLC40A1 proteinincreases expression 16614402
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1714745880
MESH:D000014 Abnormalities, Drug-Induced Ethanol 7.2518926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.2515322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 9.2518287403
MESH:D000138 Acidosis Ethanol 9.2511192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5717505938
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 4.479612607
MESH:D000169 Acrodermatitis Zinc 5.0317202136 16889938 17190629
MESH:D058186 Acute Kidney Injury Folic Acid 4.0016316344 16595132 17003819
MESH:D055371 Acute Lung Injury Lipopolysaccharides 7.9218653653 11850527
MESH:D055371 Acute Lung Injury pirinixic acid 7.9218653653
MESH:D000230 Adenocarcinoma arsenic trioxide 9.2819825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 9.2820464547 20127859
MESH:D000230 Adenocarcinoma Estradiol 9.2811473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.2814692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 14.223712494
MESH:D000236 Adenoma Benzo(a)pyrene 14.226695378
MESH:D000236 Adenoma Diethylnitrosamine 14.2210737359 6695378
MESH:D000236 Adenoma Folic Acid 14.2216963246
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 15.1417162532 18056438 17620307 16434500 19052882 19061943
MESH:D018248 Adenoma, Liver Cell pirinixic acid 15.1416434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 15.1416835633
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.9415451039 15451040
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 5.2816640825
MESH:D000544 Alzheimer Disease Copper 8.7916866297 16325427 16886094 16962711 16410023 17119284
MESH:D000544 Alzheimer Disease Folic Acid 8.7917116317
MESH:D000544 Alzheimer Disease Iron 8.7916563566 16640825
MESH:D000544 Alzheimer Disease Zinc 8.7916580781 16325427 16410023 17119284
MESH:D000686 Amyloidosis Diethylstilbestrol 4.1315469931
MESH:D000690 Amyotrophic Lateral Sclerosis Copper 4.0710694572
MESH:D000740 Anemia marker/mechanism 16434484
MESH:D000740 Anemia Iron 18.7116434484 16566752
MESH:D000740 Anemia Phenacetin 18.712444515
MESH:D000740 Anemia phenylhydrazine 18.712444515
MESH:D000740 Anemia Tetrachlorodibenzodioxin 18.7111748828
MESH:D000743 Anemia, Hemolytic Phenacetin 9.9617698508 1949026 17082564
MESH:D000743 Anemia, Hemolytic phenylhydrazine 9.9617698508 17084956 17082564
MESH:D018798 Anemia, Iron-Deficiency Copper 9.4116614410
MESH:D018798 Anemia, Iron-Deficiency Iron 9.4116569441 17147795 17162259 17375513 17163184
MESH:D000755 Anemia, Sickle Cell Zinc 4.5516916123
MESH:D000756 Anemia, Sideroblastic Iron 4.4816910769
MESH:D000853 Anophthalmos Ethanol 4.4615513904
MESH:D001008 Anxiety Disorders Ethanol 3.7211141031
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.7119183758
MESH:D001145 Arrhythmias, Cardiac Iron 4.0516604332
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.4415885639
MESH:D001249 Asthma Zinc 2.8417085522
MESH:D001260 Ataxia Telangiectasia Iron 5.0815336622
MESH:D050197 Atherosclerosis Iron 3.4916632123 16640825
MESH:D001321 Autistic Disorder marker/mechanism 15446388
MESH:D001321 Autistic Disorder Folic Acid 2.6621388746
MESH:D001321 Autistic Disorder Iron 2.6617352947
MESH:D001424 Bacterial Infections Iron 4.8316640825
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.6411289319 1440618
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 13.3816206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.3819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.3812125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5315746008
MESH:D001862 Bone Resorption bisphenol A 3.5411985600
MESH:D001930 Brain Injuries Zinc 4.3317109824
MESH:D001932 Brain Neoplasms Copper 4.2417079463
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 5.4220146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 5.4217123778
MESH:D001943 Breast Neoplasms Copper 5.4217079463 15986119
MESH:D001943 Breast Neoplasms Diethylnitrosamine 5.4217474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 5.4217129689 15324884
MESH:D001943 Breast Neoplasms Estradiol 5.4217018787 12948864 19861407 14630087 17261762 16675129 17289903 18497071
MESH:D001943 Breast Neoplasms Folic Acid 5.4216777985
MESH:D001943 Breast Neoplasms Tamoxifen 5.4219289846 17893378 16273361 20544844 20135344 18815881 18821012 17049068 18425577 19221464 19410462 15565566 18997820 19189212 20065188 19288272 20005174 19189210 19103187 19084267 17242785 15668708 19059307 16202921 18351453 19155303 19244106 18629630 18984771 19115204 11161223 19011961 16818667 20390343 19066611 19487384 16873071 17261762 21138602 19142967 20859285 19200415 21152245 18855134 17440819
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.4220435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.9911589617
MESH:D002056 Burns Ethanol 4.2916374292
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0916111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.4215700767 16011737 3786805 16097048 16227642 16192424 15721981 16124888 15673190 16050911 10355542 18705752
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5116835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1519066611
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 18.547296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 18.5412907637 21507988 12619106
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 18.5415553829 15073043 11135700 14691202 16217749
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 18.5418788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 18.5416779866 18393292 10672840 3581430 20432363 20007298 18494052 19335982 11831363 17978847 18971187 18210153 18978308 19171122 18785209 19919837 20524982 16878318 21159647 19701751 16328049 19052882 16935385 3084413 19418558 18788625 20514400 17761372 16698587 17138121 19519916 18506893 19822196 17173139 10737359 19539802 20214788 16288022 20935162 20512989 16540662 19383236 19107877 16830150 16502159 17162532 20101231 19208518 16569478 17428255 18056438 19394651 20727157 16681979 18691550 17055752 18665156 20084675 16807293
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 18.5416924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 18.5416924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 18.5418788625 15763234 15289165
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 18.5416924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.6217123778
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.5019014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 6.407296757
MESH:D002292 Carcinoma, Renal Cell ferric nitrilotriacetate 6.408340253
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.8012490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.4020419170
MESH:D002294 Carcinoma, Squamous Cell Zinc 4.4016543248
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.3017572228
MESH:D006332 Cardiomegaly Copper 10.3517327471
MESH:D006332 Cardiomegaly Ethanol 10.3519332462
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 10.3518670907 18850075 16120746
MESH:D009202 Cardiomyopathies Iron 3.8016640825
MESH:D002311 Cardiomyopathy, Dilated Iron 3.3316604332
MESH:D002318 Cardiovascular Diseases Folic Acid 6.9716755160
MESH:D002318 Cardiovascular Diseases Zinc 6.9716936243
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 13.927505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 13.9212371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 13.9217174075 21159647 7505956 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 13.9218566989
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.3019052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.3016835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 16.9919486331 9022650
MESH:D002779 Cholestasis Cyclosporine 16.9919486331
MESH:D002779 Cholestasis Ethinyl Estradiol 16.9915861022 16105132 17333356 16919318 17110522 11677210 17681005
MESH:D002779 Cholestasis pirinixic acid 16.9919176532
MESH:D002971 Cleft Lip Ethanol 7.2315513904
MESH:D002971 Cleft Lip Folic Acid 7.2321254359
MESH:D002972 Cleft Palate Ethanol 9.0215513904
MESH:D002972 Cleft Palate Folic Acid 9.028946559 21254359
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 9.0212621046 15340226 15668235 8697196 16354765
MESH:D003110 Colonic Neoplasms Iron 2.8316640825
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.7120501625
MESH:D015179 Colorectal Neoplasms Folic Acid 2.7117087956 16963246 17116713 16985020 17245555
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7514669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.8412609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 6.8510525206
MESH:D019465 Craniofacial Abnormalities Ethanol 6.8515451039 10194807 19302082 11873399 15513904 11198716 15451040
MESH:D019465 Craniofacial Abnormalities Permethrin 6.8519861644
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 6.8520055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Zinc 6.8519302082
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.2112952375 16002989
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.7615213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0019031437
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.4611298694 8156756 14531868 18759878 11906362 2524372 12868966 8970840
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2518249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 8.552952479 3621924
MESH:D003877 Dermatitis, Contact Permethrin 8.5514617103
MESH:D003920 Diabetes Mellitus Iron 8.6116604332 16640825
MESH:D003920 Diabetes Mellitus Zinc 8.6116479319
MESH:D003922 Diabetes Mellitus, Type 1 Iron 3.2416506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 9.4620387270
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 9.4616886840
MESH:D003924 Diabetes Mellitus, Type 2 Iron 9.4616506275
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 9.4617107852
MESH:D003928 Diabetic Nephropathies Estradiol 7.8219279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 7.8219279558
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 13.6911289319 18648102 18692083 9022650 18289764 9328219 6482804 7440962 16192314 8291058 1440618 9653073 6679447
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 13.6915027814 3786805 7179309 21278145 6884620 7440962 10092053 16227642 6623471 2869522 17522070 9327722 10915739 4309450 19085960 15968718 19336974 16177239 3732212 11566570 15998439 7120509
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 13.6917851650
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 13.6919107877
MESH:D056486 Drug-Induced Liver Injury Ethanol 13.6911566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 13.6920420201
MESH:D004362 Drug Toxicity Lamivudine 12.3115040536
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 12.3111462148
MESH:D004362 Drug Toxicity Zidovudine 12.3115040536
MESH:D004487 Edema perfluorooctanoic acid 9.5812083418 17259670
MESH:D004487 Edema pirinixic acid 9.5812083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 9.5812711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.5316714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 7.7912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 7.7919031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.3216402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 15.8416804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 15.8419148513 18566989 11473722
MESH:D016889 Endometrial Neoplasms Folic Acid 15.8417301261
MESH:D016889 Endometrial Neoplasms Tamoxifen 15.8419155303 16202921 20544844 17893378
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.7110568697 9294722
MESH:D019446 Endotoxemia Lipopolysaccharides 4.0315821434 15328337 17637181
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.7416302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 12.703581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 12.7012903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 12.7016530937
MESH:D004938 Esophageal Neoplasms Ethanol 12.7016704527
MESH:D004938 Esophageal Neoplasms Zinc 12.7016543248
MESH:D017889 Exfoliation Syndrome Folic Acid 5.1216504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.7411564622
MESH:D005234 Fatty Liver arsenic trioxide 49.4115073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 49.4112795759 16045604 12631006 19224547 15959796 16239168 17595544 61145
MESH:D005234 Fatty Liver Cyclosporine 49.4119224547
MESH:D005234 Fatty Liver Diethylnitrosamine 49.4120387270 21071580
MESH:D005234 Fatty Liver Ethanol 49.4116409862 19236843 18620774
MESH:D005234 Fatty Liver Ethinyl Estradiol 49.4115345470
MESH:D005234 Fatty Liver Iron 49.4116640825
MESH:D005234 Fatty Liver pirinixic acid 49.4120131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 49.4114986274 19224547
MESH:D005234 Fatty Liver Zidovudine 49.4118299183
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.2917920746
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 7.4616002989 16513791 15751030 16534752 16611131
MESH:D052776 Female Urogenital Diseases Tamoxifen 7.4616709447
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.9316946407 10194807 15451040 15513904
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1011858732
MESH:D005334 Fever Lipopolysaccharides 3.7011852909 9205823
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.646705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1614745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.8119069698
MESH:D005355 Fibrosis Carbon Tetrachloride 12.6318705752
MESH:D005355 Fibrosis Cyclosporine 12.6312639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 12.6320067830
MESH:D005621 Friedreich Ataxia Iron 5.0716640825 16604332
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.9116904648
MESH:D005756 Gastritis Ethanol 17.0815046732
MESH:D005756 Gastritis Folic Acid 17.0817171786
MESH:D005756 Gastritis Zinc 17.0817241300
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.5816452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.858708960
MESH:D005901 Glaucoma Folic Acid 4.7416504073
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.707505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2210696789
MESH:D006130 Growth Disorders Zinc 3.7217217573
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.0620471113
MESH:D006330 Heart Defects, Congenital Folic Acid 10.0616524890 17286298
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.0610048152 11294989
MESH:D006333 Heart Failure pirinixic acid 6.3920558911
MESH:D006333 Heart Failure Zinc 6.3917162251
MESH:D006335 Heart Injuries Zinc 5.3917074742
MESH:D016481 Helicobacter Infections Zinc 4.1917241300
MESH:D006402 Hematologic Diseases Zidovudine 4.3712579204
MESH:D006432 Hemochromatosis marker/mechanism 16457665
MESH:D006432 Hemochromatosis Iron 4.2217236123 16604332 16640825 16574947 17053826 17255318
MESH:C537249 Hemochromatosis, type 4 marker/mechanism
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0515720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.0716366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0111000095
MESH:D006486 Hemosiderosis Iron 4.8416604332
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.076705139
MESH:D006505 Hepatitis Carbon Tetrachloride 8.0719900420 19110552
MESH:D006509 Hepatitis B Lamivudine 4.7717703166
MESH:D019694 Hepatitis B, Chronic Lamivudine 4.7716476009 15631357 15274664 12044531 15309715
MESH:D006521 Hepatitis, Chronic Copper 4.9017338147
MESH:D006525 Hepatitis, Viral, Human Iron 5.0916640825
MESH:D006527 Hepatolenticular Degeneration Copper 16.5617182432 17109627 19888908 17276780 16607473
MESH:D006527 Hepatolenticular Degeneration Iron 16.5617182432
MESH:D006527 Hepatolenticular Degeneration Zinc 16.5617276780
MESH:D006529 Hepatomegaly Iron 17.7816890145
MESH:D006529 Hepatomegaly perfluorooctanoic acid 17.783609246
MESH:D006529 Hepatomegaly pirinixic acid 17.7819176532 18467677 16221962 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 17.7816120746 15340226 12621046
MESH:D006558 Herpes Genitalis Estradiol 4.6615709030
MESH:D015658 HIV Infections Iron 9.8916597321
MESH:D015658 HIV Infections Lamivudine 9.8911141242 20032539 17530837 9296927
MESH:D015658 HIV Infections Zidovudine 9.8920032539 11363243 11698656 17358032 11141242
MESH:D006679 HIV Seropositivity Folic Acid 5.1217209195
MESH:D019584 Hot Flashes Estradiol 3.3817088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.678697196 15340226 16354765 18606429 16959395
MESH:D006930 Hyperalgesia Ethanol 7.2818783367
MESH:D006930 Hyperalgesia perfluorooctanoic acid 7.2812083418
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1616899240
MESH:D006943 Hyperglycemia pirinixic acid 2.8720558911
MESH:D020138 Hyperhomocysteinemia Folic Acid 4.1916395265 16397167 16433478 16865747 16755160
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 9.6415034207
MESH:D006965 Hyperplasia Diethylstilbestrol 9.6414722030 12960047
MESH:D006973 Hypertension Cyclosporine 4.4510903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.4518670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.7315338365
MESH:D007006 Hypogonadism Iron 4.1416640825
MESH:D007021 Hypospadias Diethylstilbestrol 10.0516002989
MESH:D007021 Hypospadias Ethinyl Estradiol 10.0516569931 16945680
MESH:D007037 Hypothyroidism Iron 4.7216640825
MESH:D007246 Infertility Diethylstilbestrol 4.0115036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.2517937319
MESH:D007249 Inflammation Diethylnitrosamine 13.7718785209
MESH:D007249 Inflammation Lipopolysaccharides 13.7717237260 9205823 17963957 17255318 12878042
MESH:D007249 Inflammation perfluorooctanoic acid 13.7712083418
MESH:D007249 Inflammation Tamoxifen 13.7719457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 13.7712200463 12878042
MESH:D007299 Insect Bites and Stings Permethrin 5.4515189238 12749493 12971516
MESH:D007333 Insulin Resistance bisphenol A 10.9116393666
MESH:D007333 Insulin Resistance Estradiol 10.9116393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 10.9116306350
MESH:D019189 Iron Metabolism Disorders Iron 10.4717163184
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 10.4717255318
MESH:D019190 Iron Overload marker/mechanism 17052926
MESH:D007511 Ischemia Zinc 4.2716584753
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.648074119 9022650
MESH:D007569 Jaw Abnormalities Ethanol 9.0315513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.0316580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0715604871
MESH:D007674 Kidney Diseases Cyclosporine 12.7618776723 10903974 8314463
MESH:D007674 Kidney Diseases Estradiol 12.7615618244
MESH:D007674 Kidney Diseases ferric nitrilotriacetate 12.7615834431 18617210
MESH:D007674 Kidney Diseases Zinc 12.7616960431
MESH:D007676 Kidney Failure, Chronic Copper 9.3616518626
MESH:D007676 Kidney Failure, Chronic Zinc 9.3616518626
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 30.506582329
MESH:D007680 Kidney Neoplasms Cyclosporine 30.5012371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 30.5015003126 16762066 14681315
MESH:D007680 Kidney Neoplasms Estradiol 30.5015610895
MESH:D007680 Kidney Neoplasms ferric nitrilotriacetate 30.509667754 18055543
MESH:D007680 Kidney Neoplasms Tamoxifen 30.5018625569
MESH:D007680 Kidney Neoplasms Zidovudine 30.5012579204
MESH:D007859 Learning Disorders Copper 14.1617134702
MESH:D007859 Learning Disorders Diethylstilbestrol 14.1617184923
MESH:D007859 Learning Disorders Ethanol 14.1615451040
MESH:D007938 Leukemia arsenic trioxide 6.2115070760
MESH:D007938 Leukemia Permethrin 6.2112937054
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 8.7517077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 8.7520370541
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.9416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.4319077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.0720471514 19850784 16467208 16968895 17050201
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 2.9717869043 15213294 15748426 17712046 16330433 19225113 15622746 16823087 16331271 19642359 15336539 12712474 17217047 16966277 11468182 19035177 16112521 17107899 9834237 19075265 12018890 16891316 17649720 12679006 11161223
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.0016882451
MESH:D007970 Leukopenia Lipopolysaccharides 4.3315821434
MESH:D020961 Lewy Body Disease Iron 5.0716563566
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 4.868812269
MESH:D017880 Limb Deformities, Congenital Ethanol 3.5517676605
MESH:D008064 Lipidoses Tamoxifen 2.8917567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 14.1121278145 17157831 16221502 16943688 11408273 17174718 16239168 11903743 17334410
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 14.1120032147 18407596 18665156 18522880 19638242
MESH:D008103 Liver Cirrhosis Ethanol 14.1115289165
MESH:D008103 Liver Cirrhosis Iron 14.1116640825
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.7318295389
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.9715034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 10.1014716833 14748882 18263696 15370692 15876570 14620537 12898905 18210741 16116963 17922224 18156304 15338365 15730626 16638106 18429990 12389079 12958196 17944888 18376398 18006644 12632512 18166357 15893842 14512876 15123356 16248980 16027843 14716496 15650968 17805973 17525996 18481824 12609069 11481614 17640975 12445418 12445421 18412020 18395095 18472094 15673190 17869086 18339082 12666154 15996030 16033810 12586293 16097048 18251166 17481882 16192424 18277467 15818738 12649538 12546737 18054572 16011737 16015684 17976157 14724832 18187930 17698563 12741479 18705752 12667390 20821823 17766677 18395914 17714472 15925388 17708605 15931870 17557913 16136751 17761835 17900296 17565644 15057751 13678700 18472332 15362042 17823541 18205269 12632514 18420326 15052691 18317297 17721639 18418968 10355542 17631135 18279442 15959796
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 10.1014659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 10.1018166357
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 10.1012878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 10.1015474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 10.1018564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 10.1012878042
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.0416246199 15830285 16964402 17285989 15720792
MESH:D008107 Liver Diseases Diethylnitrosamine 6.0417034775
MESH:D008107 Liver Diseases Folic Acid 6.0416877991
MESH:D008108 Liver Diseases, Alcoholic Ethanol 10.3017207112 17347304
MESH:D008108 Liver Diseases, Alcoholic Iron 10.3017207112 16737972
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8015123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.3714706259 16899240
MESH:D008113 Liver Neoplasms Aflatoxin B1 39.5518177683 15890375 2125692 9163691
MESH:D008113 Liver Neoplasms arsenic trioxide 39.5514682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 39.5521137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 39.5519294768
MESH:D008113 Liver Neoplasms Copper 39.5520302851
MESH:D008113 Liver Neoplasms Diethylnitrosamine 39.5519427195 15175105 12771043 2862719 12112319 19073162 16942905 20492335 18754104 19850985 19812893 19090486 19690152 19996281 21047994 20405173 19499222 19254457 19833225 19642983 18644402 2422723 20137499 19255062 19638242 19256749 21278145 20434301 19426721 18648771 20452335 21071580 18978307 20118626 19551842 20501860 21167192 20583210 9163691 15885732 19294768 18977376 10737359 20101389
MESH:D008113 Liver Neoplasms Diethylstilbestrol 39.5516712894 15890375
MESH:D008113 Liver Neoplasms Iron 39.5516640825 20302851
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 39.5514757943 18709148
MESH:D008113 Liver Neoplasms pirinixic acid 39.5516377806 15890375 20007298
MESH:D008113 Liver Neoplasms Tamoxifen 39.5516684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 39.5516984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 20.356587162 1399818 3712494 598648
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 20.358603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 20.3520377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 20.3512014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 20.359362446 18775883 17942915 18093689 2563599 19539802 17854601 18544905 18308698 19126423 21159647 3124819 17174075 16267830 16842330 18079962 18253720 19009564 18164116 19519916 19004024 18282651
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 20.3512151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.0715213294
MESH:D055370 Lung Injury Asbestos, Crocidolite 8.1117365036
MESH:D055370 Lung Injury Lipopolysaccharides 8.1121114838
MESH:D008175 Lung Neoplasms Aflatoxin B1 12.0614755239
MESH:D008175 Lung Neoplasms arsenic trioxide 12.0611798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 12.0617053015 18816296 18520028 18569708 6695378 20064080 20464547 20135361 20869020
MESH:D008175 Lung Neoplasms Diethylnitrosamine 12.0620512841 21163286 6695378 20970405
MESH:D008175 Lung Neoplasms Iron 12.0616640825
MESH:D008175 Lung Neoplasms Tamoxifen 12.0618625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 12.0611884234 19555203
MESH:D008175 Lung Neoplasms Zidovudine 12.0618800350
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.2317718048
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.7815166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.2115700306
MESH:D008268 Macular Degeneration Iron 3.7816640825
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.1416002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.3919428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 8.6516891317 11807958 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 8.6516827153 11731420 19196722 14580682 19196723
MESH:D008325 Mammary Neoplasms, Experimental Zinc 8.6512773700
MESH:D020149 Manganese Poisoning Estradiol 11.4019453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.4019453300
MESH:D019767 Maxillofacial Abnormalities Folic Acid 5.3316832597
MESH:D008545 Melanoma Tamoxifen 1.8319393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.8115990972
MESH:D008569 Memory Disorders Ethanol 3.8415451040 18411066
MESH:D007706 Menkes Kinky Hair Syndrome Copper 5.5117109627 17268249
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.0316166281 16966607 18303189
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4116801185
MESH:D008708 Methemoglobinemia Phenacetin 4.624834387 16296465 3537620 1949026
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 5.4617358032
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.9116381670
MESH:D009101 Multiple Myeloma arsenic trioxide 2.8514977855 19549372 15949261 11468182 19417148
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 5.3017086897
MESH:D009135 Muscular Diseases pirinixic acid 3.1516239165
MESH:D009181 Mycoses Iron 5.0916640825
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.3018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 2.9316882451 16105982
MESH:D009203 Myocardial Infarction pirinixic acid 1.9919151258
MESH:D017202 Myocardial Ischemia Iron 8.2116604332
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.2112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.6316810080
MESH:D015428 Myocardial Reperfusion Injury Iron 12.6316604332
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.6316411023
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.6116624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 8.553581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.553581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 8.5519393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3919410462
MESH:D009369 Neoplasms Benzo(a)pyrene 7.1411141357
MESH:D009369 Neoplasms Diethylstilbestrol 7.1415313581
MESH:D009369 Neoplasms pirinixic acid 7.1417405874
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.6319196722 19189210 19200415
MESH:D009389 Neovascularization, Pathologic Copper 9.1217308104
MESH:D009389 Neovascularization, Pathologic Estradiol 9.1217289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.4618481113 19348381
MESH:D009404 Nephrotic Syndrome Iron 8.4617178036
MESH:D009421 Nervous System Malformations bisphenol A 20.5811399458 16427766
MESH:D009421 Nervous System Malformations Diethylstilbestrol 20.5811399458
MESH:D009421 Nervous System Malformations Estradiol 20.5816427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 20.5814600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 10.856679447
MESH:D009436 Neural Tube Defects arsenic trioxide 10.8510525206
MESH:D009436 Neural Tube Defects Folic Acid 10.8517438019
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.7020387270
MESH:D019636 Neurodegenerative Diseases Iron 7.7017296847 16604332
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.7420387270
MESH:D009503 Neutropenia Folic Acid 4.1716322990
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.599802331
MESH:D009765 Obesity pirinixic acid 1.7220558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.104026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.643988306
MESH:D010003 Osteoarthritis Iron 3.7416640825
MESH:D010024 Osteoporosis Iron 3.6316648989 16640825
MESH:D010049 Ovarian Diseases bisphenol A 4.6211985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 4.4116624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Estradiol 4.4119401270
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 7.8515580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 7.8516540662
MESH:D010190 Pancreatic Neoplasms Ethanol 7.8512384795
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3511578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 8.277296757
MESH:D010212 Papilloma Iron 8.2712065085
MESH:D010235 Paraganglioma arsenic trioxide 3.8219927285
MESH:D020447 Parasomnias Iron 5.6417352947
MESH:D010300 Parkinson Disease Iron 3.1816563566 16640825
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8712520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.106228378
MESH:D010900 Pituitary Diseases Diethylstilbestrol 12.8114722030
MESH:D010900 Pituitary Diseases Iron 12.8116604332
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.3116977796 15687265
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.5310923243
MESH:D011014 Pneumonia Lipopolysaccharides 4.1911605937 12224865
MESH:D011041 Poisoning Iron 3.9616604332
MESH:D017119 Porphyria Cutanea Tarda Iron 9.8616640825
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 9.8618163543
MESH:D011230 Precancerous Conditions Cyclosporine 7.9212371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 7.922563599
MESH:D011225 Pre-Eclampsia Iron 8.6016640825
MESH:D011225 Pre-Eclampsia Zinc 8.6017114810
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 20.2510548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 20.2517184923
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 20.2517132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 20.2511399792 11118676 11222880 11896295
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.4620887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.4620887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.3619131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.3617292933
MESH:D011471 Prostatic Neoplasms bisphenol A 2.3616740699
MESH:D011471 Prostatic Neoplasms Copper 2.3617308104 17079463
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.3617136230 15046698 15846301
MESH:D011471 Prostatic Neoplasms Estradiol 2.3616740699
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.3615067354
MESH:D011471 Prostatic Neoplasms Zinc 2.3616606632 16700911 12429649 16517595
MESH:D011528 Protozoan Infections Iron 5.6416640825
MESH:D011537 Pruritus Ethinyl Estradiol 2.9516919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.1016882103
MESH:D011629 Puberty, Precocious bisphenol A 4.4210548101
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 2.8815814490 17365031 17322281 17975199
MESH:D051437 Renal Insufficiency Folic Acid 4.4215728788
MESH:D015427 Reperfusion Injury pirinixic acid 2.2019058328
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.4910835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4918990726
MESH:D012148 Restless Legs Syndrome Iron 4.2716930377
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 8.103692021
MESH:D012162 Retinal Degeneration Zinc 8.1016584753
MESH:D012206 Rhabdomyolysis Lamivudine 5.179296927
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.6116646077
MESH:D012559 Schizophrenia Copper 4.0516842975
MESH:D012559 Schizophrenia Folic Acid 4.0516641680
MESH:D012640 Seizures Ethanol 2.939754883
MESH:D012871 Skin Diseases Folic Acid 3.1518709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 8.4519755658 10029692
MESH:D012878 Skin Neoplasms Iron 8.4512065085
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.4516192470
MESH:D013088 Spermatocele Diethylstilbestrol 17.9616709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 17.9616709447
MESH:D013088 Spermatocele Tamoxifen 17.9616709447
MESH:D013118 Spinal Cord Diseases Folic Acid 5.1216361298
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.6719457130
MESH:D013274 Stomach Neoplasms arsenic trioxide 7.7417007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 7.7420155912 2093021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 7.7418456281
MESH:D013274 Stomach Neoplasms Ethanol 7.7418456281
MESH:D013274 Stomach Neoplasms Folic Acid 7.7417171786
MESH:D013274 Stomach Neoplasms Zidovudine 7.7417696246
MESH:D013276 Stomach Ulcer Ethanol 3.2211906479 17189318 17918041 9562338 16755016 9211565
MESH:D020521 Stroke Folic Acid 4.0416517955
MESH:D019966 Substance-Related Disorders bisphenol A 3.6216045194 16684133
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.949754883
MESH:D013398 Sudden Infant Death Iron 5.0816640825
MESH:D013436 Sulfhemoglobinemia Phenacetin 6.18978859
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.8515821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8515669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5312697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 10.351399818 6582329 6587162 3712494 7505956
MESH:D013964 Thyroid Neoplasms arsenic trioxide 10.3519014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 10.357505956
MESH:D013978 Tibial Fractures Estradiol 4.3119048282
MESH:D014062 Tongue Neoplasms Zinc 4.0816543248
MESH:D016171 Torsades de Pointes arsenic trioxide 3.5915213294
MESH:D014376 Tuberculosis Iron 3.8616597321
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 17.908074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 17.9012973940 11780464 12845720 20435036
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 17.9017053015
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 17.9016712894 17306315 16452187
MESH:D001749 Urinary Bladder Neoplasms Phenacetin 17.9011144890
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 17.908653321 17572228 16712894
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 3.7216175088
MESH:D014591 Uterine Diseases bisphenol A 12.5714652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 12.5714652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 8.3115809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.3114692618
MESH:D014605 Uveitis Cyclosporine 3.611336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 9.9416513791 16002989
MESH:D014625 Vaginal Neoplasms Zidovudine 9.9412579204
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2114671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8715886252
MESH:D014985 Xerophthalmia Cyclosporine 4.0717120751
Pathway ID Pathway Name
KEGG:04978 Mineral absorption
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35805
    • No data
    Releated disease ID Related disease Name
    PA444405Hemochromatosis
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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