AutismKB 2.0

Annotation Detail for ANXA1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ANXA1 ( ANX1,LPC1 )
Gene Full Name: annexin A1
Band: 9q21.13
Quick LinksEntrez ID:301; OMIM: 151690; Uniprot ID:ANXA1_HUMAN; ENSEMBL ID: ENSG00000135046; HGNC ID: 533
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Signaling by GPCR
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1781Rheumatoid arthritis
1871Hepatitis
1896Adrenoleukodystrophy
1934Cancer
2090Hamman-Rich syndrome
2115Muscular dystrophies
Desease Name
METABOLIC
diabetes, type 2
Desease Name
Schizophrenia, bipolar disorder and depression (combined)
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in increased expression of ANXA1 mRNAincreases expression 20406850
C026137 3-hydroxyacetanilide 3-hydroxyacetanilide results in decreased expression of ANXA1 mRNAdecreases expression 18544908
C002202 4-oxoretinoic acid 4-oxoretinoic acid results in increased expression of ANXA1 mRNAincreases expression 15982314
C029728 4-phenylenediamine 4-phenylenediamine results in increased expression of ANXA1 mRNAincreases expression 16314067
D000082 Acetaminophen Acetaminophen affects the expression of ANXA1 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in increased expression of ANXA1 mRNAincreases expression 18544908
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of ANXA1 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ANXA1 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of and results in increased secretion of ANXA1 proteinincreases expression|increases secretion 18081892
D001205 Ascorbic Acid [Quercetin co-treated with Ascorbic Acid] results in increased expression of ANXA1 mRNAaffects cotreatment|increases expression 17639512
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANXA1 mRNAaffects cotreatment|increases expression 18164116
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of ANXA1 mRNAincreases expression 20018196
19150397
D002351 Carrageenan ANXA1 protein affects the susceptibility to Carrageenanaffects response to substance 12475898
D002351 Carrageenan ANXA1 protein affects the susceptibility to [Dexamethasone co-treated with Carrageenan]affects cotreatment|affects response to substance 12475898
C423222 cotylenin A cotylenin A results in increased expression of ANXA1 mRNAincreases expression 16129123
D016572 Cyclosporine Cyclosporine results in increased expression of ANXA1 mRNAincreases expression 20106945
D003907 Dexamethasone ANXA1 protein inhibits the reaction [Dexamethasone results in decreased susceptibility to IL8 protein]decreases reaction|decreases response to substance 7522859
D003907 Dexamethasone ANXA1 protein affects the susceptibility to Dexamethasoneaffects response to substance 12475898
D003907 Dexamethasone ANXA1 protein affects the susceptibility to [Dexamethasone co-treated with Carrageenan]affects cotreatment|affects response to substance 12475898
D003907 Dexamethasone ANXA1 protein affects the susceptibility to Dexamethasoneaffects response to substance 15472012
D002945 Cisplatin ANXA1 protein affects the susceptibility to Cisplatinaffects response to substance 16217747
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANXA1 mRNAaffects cotreatment|increases expression 18164116
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ANXA1 proteinaffects cotreatment|increases expression 20935162
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of ANXA1 mRNAincreases expression 19638242
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of ANXA1 proteinincreases expression 20935162
D004137 Dinitrochlorobenzene Dinitrochlorobenzene results in increased expression of ANXA1 mRNAincreases expression 16314067
D004050 Ditiocarb Ditiocarb results in increased expression of ANXA1 mRNAincreases expression 16603213
D000431 Ethanol Ethanol results in decreased expression of ANXA1 mRNAdecreases expression 15513904
D000431 Ethanol Ethanol results in decreased expression of ANXA1 mRNAdecreases expression 16946407
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of ANXA1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of ANXA1 mRNAincreases expression 17557909
D005472 Fluorouracil ANXA1 protein affects the susceptibility to Fluorouracilaffects response to substance 16217747
15352031
D005472 Fluorouracil Fluorouracil results in decreased expression of ANXA1 proteindecreases expression 15352031
D005480 Flurbiprofen Flurbiprofen results in increased expression of ANXA1 mRNAincreases expression 16949054
C065382 fluticasone fluticasone affects the localization of ANXA1 proteinaffects localization 15753895
C071834 glycidamide glycidamide results in decreased expression of ANXA1 mRNAdecreases expression 17822822
D006581 Hexachlorobenzene Hexachlorobenzene results in increased expression of ANXA1 mRNAincreases expression 15159207
D007052 Ibuprofen Ibuprofen affects the expression of ANXA1 mRNAaffects expression 17070997
C011890 kojic acid kojic acid results in decreased expression of ANXA1 mRNAdecreases expression 16595896
D008070 Lipopolysaccharides ANXA1 protein affects the reaction [Lipopolysaccharides affects the secretion of IL6 protein]affects reaction|affects secretion 16633358
D008070 Lipopolysaccharides ANXA1 protein affects the reaction [Lipopolysaccharides affects the secretion of TNF protein]affects reaction|affects secretion 16633358
D015735 Mifepristone Mifepristone results in increased expression of ANXA1 mRNAincreases expression 17584828
D009151 Mustard Gas Mustard Gas results in increased expression of ANXA1 mRNAincreases expression 18988085
C029938 nickel sulfate nickel sulfate results in increased expression of ANXA1 mRNAincreases expression 16314067
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of ANXA1 mRNAincreases expression 17616710
D010126 Ozone Ozone results in increased expression of ANXA1 mRNAincreases expression 12763052
D017239 Paclitaxel ANXA1 protein results in increased susceptibility to Paclitaxelincreases response to substance 16734730
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of ANXA1 mRNAincreases expression 16221955
D010634 Phenobarbital [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ANXA1 proteinaffects cotreatment|increases expression 20935162
D011794 Quercetin [Quercetin co-treated with Ascorbic Acid] results in increased expression of ANXA1 mRNAaffects cotreatment|increases expression 17639512
D011794 Quercetin Quercetin results in increased expression of ANXA1 proteinincreases expression 15221776
D011794 Quercetin Quercetin results in decreased expression of ANXA1 mRNAdecreases expression 18095365
C037219 quinoline quinoline analog results in increased expression of ANXA1 proteinincreases expression 18645022
C116926 rofecoxib rofecoxib affects the expression of ANXA1 mRNAaffects expression 17070997
C017947 sodium arsenite sodium arsenite results in increased expression of ANXA1 proteinincreases expression 15899475
D018038 Sodium Selenite Sodium Selenite results in increased expression of ANXA1 mRNAincreases expression 18175754
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of ANXA1 mRNAincreases expression 20067830
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of ANXA1 mRNAdecreases expression 15667827
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of ANXA1 mRNAincreases expression 17035482
15591033
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of ANXA1 mRNAincreases expression 16267337
D013876 Thiophenes Thiophenes analog promotes the reaction [Tretinoin results in increased expression of ANXA1 mRNA]increases expression|increases reaction 16140955
D014212 Tretinoin Thiophenes analog promotes the reaction [Tretinoin results in increased expression of ANXA1 mRNA]increases expression|increases reaction 16140955
D014212 Tretinoin Tretinoin results in increased expression of ANXA1 mRNAincreases expression 15982314
16140955
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of ANXA1 mRNAincreases expression 17982090
C025643 vinclozolin vinclozolin affects the expression of ANXA1 mRNAaffects expression 19015723
D015032 Zinc Zinc affects the expression of ANXA1 mRNAaffects expression 16979875
D015054 Zymosan ANXA1 gene mutant form results in decreased export of Zymosandecreases export 16633358
D015054 Zymosan ANXA1 gene mutant form results in decreased uptake of Zymosandecreases uptake 16633358
D015054 Zymosan ANXA1 protein affects the reaction [Zymosan affects the secretion of TNF protein]affects reaction|affects secretion 16633358
D015054 Zymosan ANXA1 protein affects the susceptibility to Zymosanaffects response to substance 12475898
D015054 Zymosan ANXA1 protein results in increased uptake of Zymosanincreases uptake 12475898
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 11.2718926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 11.276195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 11.2715322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 8.7518287403
MESH:D000138 Acidosis Ethanol 8.7511192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.4117505938
MESH:D000169 Acrodermatitis Zinc 4.8816889938 17190629 17202136
MESH:D058186 Acute Kidney Injury Cisplatin 7.5712690470 15814532 17670903
MESH:D058186 Acute Kidney Injury Ibuprofen 7.576375363
MESH:D055371 Acute Lung Injury Lipopolysaccharides 7.9018653653 11850527
MESH:D055371 Acute Lung Injury nickel sulfate 7.9016100012 19131640 12718980 11954676
MESH:D000230 Adenocarcinoma arsenic trioxide 11.8411798837 19825857
MESH:D000230 Adenocarcinoma Cisplatin 11.8411798837 17638652
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 11.8414692618
MESH:D000230 Adenocarcinoma Fluorouracil 11.8417638652
MESH:D000230 Adenocarcinoma Ibuprofen 11.8410697514
MESH:D000236 Adenoma beta-Naphthoflavone 5.8219389873
MESH:D000236 Adenoma Diethylnitrosamine 5.826695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 14.3517162532 19061943 18056438 19052882 16434500 17620307
MESH:D018248 Adenoma, Liver Cell Phenobarbital 14.3517620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 14.3516835633
MESH:D011125 Adenomatous Polyposis Coli Flurbiprofen 4.6210680582
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.1715276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.3717306315 16712894
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.7915451039 15451040
MESH:D000505 Alopecia Tretinoin 3.2015955085
MESH:D000544 Alzheimer Disease Ibuprofen 5.9618351690
MESH:D000544 Alzheimer Disease Ozone 5.9615513908
MESH:D000544 Alzheimer Disease Zinc 5.9616410023 16580781 17119284 16325427
MESH:D000707 Anaphylaxis Ibuprofen 4.749532969
MESH:D000740 Anemia Fluorouracil 12.3216511603 15504547 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 12.3211748828
MESH:D000740 Anemia Zymosan 12.3218664788
MESH:D000743 Anemia, Hemolytic Quercetin 3.7817084956
MESH:D000755 Anemia, Sickle Cell Zinc 4.4116916123
MESH:D000799 Angioedema Acetaminophen 3.3210982225
MESH:D000853 Anophthalmos Ethanol 4.3115513904
MESH:D001008 Anxiety Disorders Ethanol 7.6411141031
MESH:D001008 Anxiety Disorders vinclozolin 7.6419015723
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 2.9611256880
MESH:D001169 Arthritis, Experimental Carrageenan 24.3917392412
MESH:D001169 Arthritis, Experimental Dexamethasone 24.3917659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 24.3915885639
MESH:D001169 Arthritis, Experimental rofecoxib 24.3916690336
MESH:D001169 Arthritis, Experimental Tretinoin 24.3916412693
MESH:D001169 Arthritis, Experimental Zymosan 24.3915142272 15944321 15188379 17659584 16872482
MESH:D001172 Arthritis, Rheumatoid Ozone 4.1715570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.1716292516
MESH:D001249 Asthma fluticasone 12.9811991558 11101185 11596838
MESH:D001249 Asthma Mustard Gas 12.9810378619
MESH:D001249 Asthma Ozone 12.9817854713 16373670
MESH:D001249 Asthma Tretinoin 12.9816456186
MESH:D001249 Asthma Zinc 12.9817085522
MESH:D001260 Ataxia Telangiectasia Quercetin 4.4615336622
MESH:D001321 Autistic Disorder Acetaminophen 1.4818445737
MESH:D001327 Autoimmune Diseases Quercetin 3.9019761891
MESH:D001471 Barrett Esophagus Tretinoin 3.9116935849
MESH:D001768 Blister Mustard Gas 4.6419167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 12.6616206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 12.6612125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 12.6616206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.2615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4215746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.3614601052
MESH:D001859 Bone Neoplasms Paclitaxel 4.0915867366
MESH:D001930 Brain Injuries Zinc 4.1817109824
MESH:D002545 Brain Ischemia Ibuprofen 4.3715837124
MESH:D001943 Breast Neoplasms Ascorbic Acid 5.1616443354
MESH:D001943 Breast Neoplasms Cisplatin 5.1618382427 19526202
MESH:D001943 Breast Neoplasms Diethylnitrosamine 5.1617474063
MESH:D001943 Breast Neoplasms Fluorouracil 5.1619217205 18608205 18357371 16595493 16110121 16557594 15136595
MESH:D001943 Breast Neoplasms Hexachlorobenzene 5.1615061365 12709520
MESH:D001943 Breast Neoplasms Paclitaxel 5.1618323546 16244791 11325840 16273361 18234424 15136595 16115903 18223236
MESH:D001943 Breast Neoplasms Quercetin 5.1618628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.1620435547
MESH:D001943 Breast Neoplasms Tretinoin 5.1616873071 16166294 16443354
MESH:D016535 Bronchial Hyperreactivity Ozone 3.2715516495 14754758 16777450 19059883 17626835 18315731 18417511
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.6415286001
MESH:D029481 Bronchitis, Chronic fluticasone 11.8717687719
MESH:D029481 Bronchitis, Chronic Mustard Gas 11.8717687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.0716813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.8511589617
MESH:D002056 Burns Ethanol 4.1516374292
MESH:D002100 Cachexia Ibuprofen 10.8415141370
MESH:D002100 Cachexia Ozone 10.8416183385
MESH:D002105 Cadmium Poisoning Quercetin 5.0216962696
MESH:D002276 Carcinoid Tumor Fluorouracil 4.1416051944
MESH:D002277 Carcinoma Fluorouracil 6.8217121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.8216835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.6316168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 32.9516705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 32.953084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 32.9512907637 12619106 21507988
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 32.9514691202 15073043 16217749 15553829 11135700
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 32.9517982673
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 32.9520512989 16830150 17162532 11831363 20514400 16807293 17055752 20524982 18056438 19519916 20727157 18978308 20101231 10737359 17761372 20084675 20432363 3581430 18971187 19394651 18788625 19335982 20214788 17428255 16681979 20935162 18393292 16698587 16502159 16540662 19383236 18785209 16935385 19052882 18494052 19822196 18665156 19171122 16328049 17138121 16878318 19701751 16569478 16779866 19919837 3084413 19107877 17978847 10672840 21159647 19418558 16288022 18691550 20007298 19208518 17173139 18506893 18210153 19539802
MESH:D006528 Carcinoma, Hepatocellular Ethanol 32.9515289165 15763234 18788625
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 32.9517088986 16799960 17971768 18930000 17045692 16332177
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 32.9516313753
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 32.9520007298 1701930 17173139 6705139 20935162
MESH:D006528 Carcinoma, Hepatocellular Quercetin 32.9519519916 12508355
MESH:D006528 Carcinoma, Hepatocellular quinoline 32.95598648
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 32.9517306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 32.951917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.8416685392 12023789
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.4517234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.3519014326
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.7618695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.6612490120
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 12.4117066447 6189445 18337622
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 12.4118986760 17066447 16280240 16757204
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 12.4118572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 12.4116096774 16051514
MESH:D002294 Carcinoma, Squamous Cell Zinc 12.4116543248
MESH:D006332 Cardiomegaly Ethanol 9.6819332462
MESH:D006332 Cardiomegaly Quercetin 9.6819794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 9.6818670907 16120746 18850075
MESH:D002318 Cardiovascular Diseases Zinc 3.3016936243
MESH:D002386 Cataract Acetaminophen 6.1510977129
MESH:D002386 Cataract Tretinoin 6.1517460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 17.206135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 17.2020889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 17.2012371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 17.202727394 7505956 21159647 17174075
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 17.2020056578 19524636
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.754080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.0716129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.8719052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.8716835633
MESH:D002779 Cholestasis Cyclosporine 6.4819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 6.4815861022 11677210 17110522 17333356 16105132 16919318 17681005
MESH:D002822 Choriocarcinoma Tretinoin 4.6316461808
MESH:D019457 Chromosome Breakage Sodium Selenite 4.2515894690
MESH:D002971 Cleft Lip Ethanol 3.3015513904
MESH:D002972 Cleft Palate Ethanol 8.4315513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 8.4315340226 16354765 8697196 12621046 15668235
MESH:D002972 Cleft Palate Tretinoin 8.439407595
MESH:D003092 Colitis Tretinoin 8.1017035595
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 8.1018023891 16782535 17991707 16804969 17936198 11698051 16867261 16474422 18200517
MESH:D003093 Colitis, Ulcerative Dinitrochlorobenzene 5.8419159591 17373747
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 5.8417276891
MESH:D003110 Colonic Neoplasms Dexamethasone 7.3515824018
MESH:D003110 Colonic Neoplasms Fluorouracil 7.3518772588 16510598 17287894 15001691 17016597 17725105 17172411 16340194 17018589 17169374
MESH:D003110 Colonic Neoplasms Quercetin 7.3511134977 15741050 19056647 16640504 17191121 19440933 17148506
MESH:D003110 Colonic Neoplasms rofecoxib 7.3512902858
MESH:D015179 Colorectal Neoplasms arsenic trioxide 5.7820501625
MESH:D015179 Colorectal Neoplasms Cisplatin 5.7815273666
MESH:D015179 Colorectal Neoplasms Fluorouracil 5.7817094418 16331619 17255274 15148649 17016601 17401013 16391804 18383874 18448328 14970324 18949393 15289873 18288408 18802399 17594712 16282729 18509181 20501625 16303861 17695437 17454858 16524972
MESH:D015179 Colorectal Neoplasms Paclitaxel 5.7818802399
MESH:D015179 Colorectal Neoplasms Quercetin 5.7818852136 18095365
MESH:D003139 Common Cold Ascorbic Acid 4.9517323712
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.6214669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.6912609071
MESH:D019465 Craniofacial Abnormalities marker/mechanism 17405164
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 8.4710525206
MESH:D019465 Craniofacial Abnormalities Dexamethasone 8.4717728286
MESH:D019465 Craniofacial Abnormalities Ethanol 8.4710194807 19302082 11873399 15451039 15451040 15513904 11198716
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 8.4720055451 15322242 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 8.4716925845 9664655 9142499 10589399 8800419 14991402 9224671 9125849 9211117 17551590
MESH:D019465 Craniofacial Abnormalities Zinc 8.4719302082
MESH:D003456 Cryptorchidism vinclozolin 3.8514966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.5118551238
MESH:D007644 Darier Disease Fluorouracil 4.2716733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.6215213294
MESH:D017449 Dermatitis, Allergic Contact 4-phenylenediamine 12.6119470301 11298694 11906362 16533241 16823706 18759875
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 12.6112438553
MESH:D017449 Dermatitis, Allergic Contact Dinitrochlorobenzene 12.6115491423
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 12.6116823706 11298694 16780908
MESH:D003877 Dermatitis, Contact 4-phenylenediamine 4.8611531941
MESH:D003920 Diabetes Mellitus Sodium Selenite 7.9316285004
MESH:D003920 Diabetes Mellitus Zinc 7.9316479319
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.3119496084
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 6.2716506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.2720387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.2717107852
MESH:D003967 Diarrhea Dexamethasone 3.227237001
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 12.8521346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.8517522070 11461765 11421492 11739529 11287661 14725611 19739265 19416960 10915739 12153990 16081117 12540782 15968718 11529661 16109766 14550746 17906064 12705907 14986274 12392966 19420014 18071297 19085960 16781746 15619225 17562736 19923254 16485898 16177239 19370779 10774834 16393943 19164858 18713872 2444490 10663392 16227642 11743745 12594235 12958197 11834606
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 12.8519107877
MESH:D056486 Drug-Induced Liver Injury Ethanol 12.8511566570
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 12.8515131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.8520420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.5719426721
MESH:D004362 Drug Toxicity Cisplatin 6.8819839026 12231392 12649298 15033597
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.8811462148
MESH:D004374 Ductus Arteriosus, Patent Ibuprofen 5.0916133044 18446180 18450898
MESH:D004421 Dystonia Phenobarbital 3.531851702
MESH:C538011 Eales disease Ascorbic Acid 4.959068938
MESH:D004485 Eczema Dexamethasone 3.9712438553
MESH:D004487 Edema Carrageenan 21.1112798668 18841975 16100529 10653021 15860553 8985016 18449507 17259670 18621150 12083418 12787963
MESH:D004487 Edema Dexamethasone 21.1119703484
MESH:D004487 Edema Mustard Gas 21.1111402378 11428647 11428631 9260866
MESH:D004487 Edema perfluorooctanoic acid 21.1117259670 12083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 21.1111000095 12711302
MESH:D004487 Edema Zymosan 21.117907874
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.1915322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.1918230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 2.7012538720
MESH:D016889 Endometrial Neoplasms Tretinoin 2.7616569247
MESH:D004715 Endometriosis Ibuprofen 18.2415652904
MESH:D004715 Endometriosis Mifepristone 18.2416134523
MESH:D004715 Endometriosis rofecoxib 18.2415652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 18.249294722 10568697
MESH:D019446 Endotoxemia Ibuprofen 9.1011545620
MESH:D019446 Endotoxemia Lipopolysaccharides 9.1015821434 17637181 15328337
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.603659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.3511558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.6120417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.116401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.757750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.503659116
MESH:D004890 Erythema Mustard Gas 4.649357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.5916302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 22.3420426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 22.3412903497
MESH:D004938 Esophageal Neoplasms Cisplatin 22.3416481741 15464296 16785472 15173087 17638652
MESH:D004938 Esophageal Neoplasms Ethanol 22.3416704527
MESH:D004938 Esophageal Neoplasms Fluorouracil 22.3415173087 16337965 17638652 16785472 16481741
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 22.3415547733 15264214 16805852 15878914 15150132 16704527 15623463 16510608 15547721
MESH:D004938 Esophageal Neoplasms Paclitaxel 22.3416481741
MESH:D004938 Esophageal Neoplasms Zinc 22.3416543248
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.5311564622
MESH:D005124 Eye Abnormalities Tretinoin 7.5316938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 19.7615073043
MESH:D005234 Fatty Liver Cyclosporine 19.7619224547
MESH:D005234 Fatty Liver Diethylnitrosamine 19.7621071580 20387270
MESH:D005234 Fatty Liver Ethanol 19.7619236843 18620774 16409862
MESH:D005234 Fatty Liver Ethinyl Estradiol 19.7615345470
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.1417920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.7810194807 15451040 16946407 15513904
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.9511858732
MESH:D005334 Fever Ibuprofen 8.0316997862
MESH:D005334 Fever Lipopolysaccharides 8.0311852909 9205823
MESH:D005354 Fibrosarcoma Carrageenan 5.7610962813
MESH:D005355 Fibrosis Cyclosporine 22.4112168785 12639820
MESH:D005355 Fibrosis Quercetin 22.4119474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 22.4120067830
MESH:D005355 Fibrosis Tretinoin 22.4117994277
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 22.4117994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.7716904648
MESH:D005756 Gastritis Acetaminophen 16.0116983495
MESH:D005756 Gastritis Ethanol 16.0115046732
MESH:D005756 Gastritis Zinc 16.0117241300
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.4216973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.7716417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.1616452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.708708960
MESH:D005909 Glioblastoma Quercetin 6.0919804834
MESH:D005909 Glioblastoma Tretinoin 6.0917312396
MESH:D005910 Glioma Fluorouracil 5.4116145905
MESH:D005910 Glioma Quercetin 5.4117643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.0710696789
MESH:D006130 Growth Disorders Zinc 3.6217217573
MESH:D006258 Head and Neck Neoplasms Cisplatin 10.9115464296 15102660
MESH:D006258 Head and Neck Neoplasms Fluorouracil 10.9118337622 15102660 15162350
MESH:D006258 Head and Neck Neoplasms Tretinoin 10.9116096774
MESH:D034381 Hearing Loss Cisplatin 3.8619898482
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.6316084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.9915464296
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 9.5316080930
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.5311294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 9.539664655 14991402
MESH:D006333 Heart Failure Zinc 3.2817162251
MESH:D006335 Heart Injuries Zinc 5.2417074742
MESH:D016481 Helicobacter Infections Zinc 4.0617241300
MESH:D006390 Hemangioendothelioma quinoline 5.38598648
MESH:D006394 Hemangiosarcoma quinoline 4.53598648
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9015720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.9316366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.8711000095
MESH:D006505 Hepatitis Zymosan 4.2119110552
MESH:D006527 Hepatolenticular Degeneration Zinc 4.1817276780
MESH:D006529 Hepatomegaly perfluorooctanoic acid 11.623609246
MESH:D006529 Hepatomegaly Phenobarbital 11.6216109766
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 11.6215340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 5.5616863852 16490937
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 5.567520565
MESH:D006689 Hodgkin Disease Cisplatin 6.1116170182 16200630
MESH:D006689 Hodgkin Disease sodium arsenite 6.1112676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.5216959395 15340226 16354765 18606429 8697196
MESH:D006930 Hyperalgesia Acetaminophen 15.3116870215
MESH:D006930 Hyperalgesia Ethanol 15.3118783367
MESH:D006930 Hyperalgesia perfluorooctanoic acid 15.3112083418
MESH:D006930 Hyperalgesia Tretinoin 15.3116870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.0616778211
MESH:D006943 Hyperglycemia Quercetin 3.5811834736 18262572
MESH:D006973 Hypertension Cyclosporine 10.5210903974
MESH:D006973 Hypertension Dexamethasone 10.5217042910
MESH:D006973 Hypertension Quercetin 10.5218356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 10.5218850075 18670907
MESH:D006984 Hypertrophy Ibuprofen 4.5116672835
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3016945680 16569931
MESH:D007235 Infant, Premature, Diseases Ibuprofen 5.3116133044
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.9812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 9.1417937319
MESH:D007248 Infertility, Male sodium arsenite 9.1415346721 12646999
MESH:D007248 Infertility, Male vinclozolin 9.1416467254
MESH:D007249 Inflammation Carrageenan 31.4310653021 16100529 8985016 18295198 12787963 12798668 19934399 12428691 7907874
MESH:D007249 Inflammation Dexamethasone 31.438960868 11099482
MESH:D007249 Inflammation Diethylnitrosamine 31.4318785209
MESH:D007249 Inflammation Flurbiprofen 31.4311099482
MESH:D007249 Inflammation Ibuprofen 31.433291741
MESH:D007249 Inflammation Lipopolysaccharides 31.4312878042 17255318 17237260 9205823 17963957
MESH:D007249 Inflammation Mustard Gas 31.439260866 11402378 11428631 16001271 11428620 11428647 9357497 17524151 8975870
MESH:D007249 Inflammation perfluorooctanoic acid 31.4312083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 31.4312200463 12878042
MESH:D007249 Inflammation Zymosan 31.438014878 11289658
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 3.3518200517
MESH:D007251 Influenza, Human Quercetin 3.9816624496
MESH:D007333 Insulin Resistance Sodium Selenite 2.9314714311
MESH:D007410 Intestinal Diseases rofecoxib 13.7215831440
MESH:D007410 Intestinal Diseases Tretinoin 13.7217994277
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 13.7217994277
MESH:D007417 Intestinal Polyps rofecoxib 4.8911245490
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.1517255318
MESH:D043183 Irritable Bowel Syndrome Zymosan 5.3217553498
MESH:D007511 Ischemia Zinc 4.1316584753
MESH:D007569 Jaw Abnormalities Ethanol 14.5015513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 14.5016580747
MESH:D007569 Jaw Abnormalities Tretinoin 14.5017551590 15992940
MESH:D007627 Keloid Quercetin 4.4517086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.9115604871
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.6115464296
MESH:D007674 Kidney Diseases Acetaminophen 19.7615629191 12587719
MESH:D007674 Kidney Diseases Cisplatin 19.7619839026 18289764 12231392 15190930 12649298
MESH:D007674 Kidney Diseases Cyclosporine 19.768314463 18776723 10903974
MESH:D007674 Kidney Diseases Quercetin 19.7616962696
MESH:D007674 Kidney Diseases sodium arsenite 19.7620008137
MESH:D007674 Kidney Diseases Zinc 19.7616960431
MESH:D007676 Kidney Failure, Chronic Zinc 3.9616518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 9.9716705839
MESH:D007680 Kidney Neoplasms Cyclosporine 9.9712371664
MESH:D007680 Kidney Neoplasms Fluorouracil 9.9716985049
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.2711231351
MESH:D007859 Learning Disorders Ethanol 3.7115451040
MESH:D007938 Leukemia arsenic trioxide 8.8815070760
MESH:D007938 Leukemia Quercetin 8.8817468513
MESH:D007938 Leukemia Tretinoin 8.8817143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.3317077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.7916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.0414633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 7.9319077051
MESH:D007951 Leukemia, Myeloid Tretinoin 7.9316482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.4919850784 20471514 16968895 17050201 16467208
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.4916294345 17596541 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 10.9117869043 12712474 11161223 17649720 15622746 17712046 19075265 16891316 12679006 15213294 15336539 17107899 16330433 9834237 16966277 19642359 19225113 16823087 19035177 16112521 12018890 17217047 15748426 16331271 11468182
MESH:D015473 Leukemia, Promyelocytic, Acute Thiophenes 10.9116140955 16140954
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 10.9117712046 9834237 16788101 16331271 17107899 16140955 19075265 19035177 19642359 17217047 17339181 15748426 17506722 17368321 19029980 16766008 16891316 17294898 17301526 16935935 17649720 17361223 16823087 19225113 12679006
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.8616882451
MESH:D007970 Leukopenia Lipopolysaccharides 4.1815821434
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 11.218812269
MESH:D007984 Leydig Cell Tumor vinclozolin 11.2116417039
MESH:D017880 Limb Deformities, Congenital Ethanol 7.0517676605
MESH:D017880 Limb Deformities, Congenital Tretinoin 7.059224671
MESH:D008080 Liposarcoma Paclitaxel 4.3417353645
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 9.3218522880 19638242 18407596 20032147 18665156
MESH:D008103 Liver Cirrhosis Ethanol 9.3215289165
MESH:D008103 Liver Cirrhosis Phenobarbital 9.3221047994
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.5818295389
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 9.6116718785
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 9.6118166357
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 9.6112878042
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 9.6112741479
MESH:D008106 Liver Cirrhosis, Experimental rofecoxib 9.6117565644
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 9.6112878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 9.6118397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 5.5319460945 12969438 19014921 16611625 11587558 19784758 12587719 16610002
MESH:D008107 Liver Diseases Diethylnitrosamine 5.5317034775
MESH:D008107 Liver Diseases Phenobarbital 5.5319363144
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.1517347304 17207112
MESH:D017114 Liver Failure, Acute Acetaminophen 2.7917185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 33.407678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 33.4018177683 15890375 9163691 2125692
MESH:D008113 Liver Neoplasms arsenic trioxide 33.4014682389
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 33.4021295105 19389873
MESH:D008113 Liver Neoplasms Diethylnitrosamine 33.4019255062 18978307 19642983 19294768 21071580 20434301 21167192 2422723 20405173 19812893 10737359 20452335 20492335 19551842 2862719 15175105 20583210 18977376 9163691 20118626 19256749 15885732 19996281 19090486 18644402 19254457 21278145 20501860 19690152 19850985 19833225 18648771 21047994 20101389 19638242 19499222 20137499 16942905 19073162 12771043 12112319 19427195 19426721 18754104
MESH:D008113 Liver Neoplasms Fluorouracil 33.4018383874 15113037 17045692 16603448
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 33.4018709148 14757943
MESH:D008113 Liver Neoplasms Phenobarbital 33.4021047994 8742319 19073162 15975961 19812893 19482888
MESH:D008113 Liver Neoplasms Quercetin 33.4018980244
MESH:D008113 Liver Neoplasms sodium arsenite 33.4015276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 33.4016984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 40.972876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 40.978603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 40.9720377131
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 40.9718544905
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 40.9718164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 40.9718308698 18775883 16842330 18093689 9362446 19126423 18164116 17174075 18253720 16267830 17942915 18079962 18282651 2563599 19519916 19009564 3124819 19004024 21159647 18544905 19539802 17854601
MESH:D008114 Liver Neoplasms, Experimental Hexachlorobenzene 40.971423854
MESH:D008114 Liver Neoplasms, Experimental kojic acid 40.9718544905
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 40.976150874 1399818 18308698 2563599 17172636
MESH:D008114 Liver Neoplasms, Experimental Quercetin 40.9719519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 40.9712151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.9515213294
MESH:D008171 Lung Diseases Ascorbic Acid 14.6916863852
MESH:D008171 Lung Diseases Mustard Gas 14.6918161513 18702808
MESH:D008171 Lung Diseases Ozone 14.698266340 19066396
MESH:D008171 Lung Diseases sodium arsenite 14.6919095001
MESH:D055370 Lung Injury Lipopolysaccharides 7.5721114838
MESH:D055370 Lung Injury Ozone 7.5720417186
MESH:D008175 Lung Neoplasms Aflatoxin B1 21.0414755239
MESH:D008175 Lung Neoplasms arsenic trioxide 21.0411798837 19825857
MESH:D008175 Lung Neoplasms Ascorbic Acid 21.0416401635
MESH:D008175 Lung Neoplasms Cisplatin 21.0417225452 11798837 6189445
MESH:D008175 Lung Neoplasms Dexamethasone 21.0415824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 21.0421163286 20970405 20512841 6695378
MESH:D008175 Lung Neoplasms Fluorouracil 21.0415246190
MESH:D008175 Lung Neoplasms Mustard Gas 21.048781369 3148597
MESH:D008175 Lung Neoplasms Ozone 21.047614698 8597069
MESH:D008175 Lung Neoplasms Quercetin 21.0416280456
MESH:D008175 Lung Neoplasms sodium arsenite 21.0415276417 16712894 17306315 19931552 17077188
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 21.0419555203 11884234
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.2715086387
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 3.5814737004
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 3.6714749477
MESH:D008325 Mammary Neoplasms, Experimental Ibuprofen 5.5010697514
MESH:D008325 Mammary Neoplasms, Experimental Zinc 5.5012773700
MESH:D008527 Medulloblastoma Tretinoin 2.5617453147
MESH:D008545 Melanoma Cisplatin 8.5612374674 15577323 18332650 18176117 12883367 11135225 16248763 12393984 17761969 16809738 18505091 17023156 16432458
MESH:D008545 Melanoma Dinitrochlorobenzene 8.5617334785 12202904
MESH:D008545 Melanoma Paclitaxel 8.5616342250 12025231 12040289
MESH:D008545 Melanoma sodium arsenite 8.5616487513 19082730
MESH:D008545 Melanoma Tretinoin 8.5616752155
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.2615990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.0619513568
MESH:D008569 Memory Disorders Ethanol 3.7018411066 15451040
MESH:D008591 Meningomyelocele Tretinoin 3.9216940565
MESH:D008654 Mesothelioma Cisplatin 3.0217638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.2616801185
MESH:D008679 Metaplasia Ozone 4.5810496685
MESH:D009062 Mouth Neoplasms Fluorouracil 3.2318986760 16757204
MESH:D009101 Multiple Myeloma arsenic trioxide 10.0411468182 14977855 19549372 15949261 19417148
MESH:D009101 Multiple Myeloma Dexamethasone 10.0415867202 15744524 16118317
MESH:D009101 Multiple Myeloma Paclitaxel 10.0414749477
MESH:D009102 Multiple Organ Failure Zymosan 4.7317724436 12130978 15834315 10479408 12879239 15213630 15259001 15241586 10890648 18160304
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.1418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 10.5416882451 16105982
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 10.549809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 10.5417596541
MESH:D009203 Myocardial Infarction Quercetin 2.7619595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6112213967
MESH:D015428 Myocardial Reperfusion Injury Quercetin 3.3919207477
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.9617484760
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.357678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.4716624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.409029167 3581430
MESH:D009362 Neoplasm Metastasis Paclitaxel 8.4015867366
MESH:D009362 Neoplasm Metastasis quinoline 8.40598648
MESH:D009369 Neoplasms Cisplatin 12.7816773208
MESH:D009369 Neoplasms Fluorouracil 12.7818239605 18600527 16928823
MESH:D009369 Neoplasms Quercetin 12.7815185748
MESH:D009369 Neoplasms sodium arsenite 12.7811559025
MESH:D009369 Neoplasms Tretinoin 12.7816946489 16594593
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.1720056578
MESH:D009395 Nephritis, Interstitial Cisplatin 9.1615464296
MESH:D009395 Nephritis, Interstitial Ibuprofen 9.166375363
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.9117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.8519348381 18481113
MESH:D009410 Nerve Degeneration Ibuprofen 3.9910961664
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 7.8814600291
MESH:D009421 Nervous System Malformations Tretinoin 7.889125849
MESH:D009436 Neural Tube Defects arsenic trioxide 10.1210525206
MESH:D009436 Neural Tube Defects sodium arsenite 10.1212854658
MESH:D009436 Neural Tube Defects Tretinoin 10.129142499
MESH:D009447 Neuroblastoma Cisplatin 3.168761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 6.7718514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 6.7720387270
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.188761367
MESH:D020078 Neurogenic Inflammation Quercetin 3.8817929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.5920387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.0816436463
MESH:D009503 Neutropenia Mustard Gas 3.507688884 16761898
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.459802331
MESH:D009765 Obesity Ascorbic Acid 3.0017217161
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 2.9816049721
MESH:D010003 Osteoarthritis Ibuprofen 7.217009135
MESH:D010003 Osteoarthritis rofecoxib 7.2116690336
MESH:D010014 Osteolysis Paclitaxel 4.4615867366
MESH:D010018 Osteomalacia Phenobarbital 3.8517016548
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 3.7419495926
MESH:D010051 Ovarian Neoplasms arsenic trioxide 19.9816624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Cisplatin 19.986897625 19769630 17225452 15464296
MESH:D010051 Ovarian Neoplasms Mifepristone 19.9816525653
MESH:D010051 Ovarian Neoplasms Paclitaxel 19.9811161223
MESH:D010051 Ovarian Neoplasms Quercetin 19.9819005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 19.9815276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 19.9816936753
MESH:D010146 Pain Acetaminophen 8.9116870215
MESH:D010146 Pain Ibuprofen 8.913291741
MESH:D010146 Pain Tretinoin 8.9116870215
MESH:D010149 Pain, Postoperative Ibuprofen 9.9816678543
MESH:D010149 Pain, Postoperative rofecoxib 9.9816678543 18165598
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 29.7715580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 29.7719003803
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 29.7716540662
MESH:D010190 Pancreatic Neoplasms Ethanol 29.7712384795
MESH:D010190 Pancreatic Neoplasms Fluorouracil 29.7716500647 16929163 19003803 15113037
MESH:D010190 Pancreatic Neoplasms Ibuprofen 29.7712384795
MESH:D010190 Pancreatic Neoplasms Phenobarbital 29.7716965848
MESH:D010190 Pancreatic Neoplasms Quercetin 29.7716965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 29.7715976015
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 3.7317698068
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2111578682
MESH:D010235 Paraganglioma arsenic trioxide 3.6819927285
MESH:D010300 Parkinson Disease Ditiocarb 4.1111445065
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.7212520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.8215464296
MESH:D010538 Peritonitis Ozone 8.7416369182
MESH:D010538 Peritonitis Zymosan 8.7415259001 17371808 19641140 15979727 18977430 18557954 17826846 19088179 11985352 18760300 14761945
MESH:D010997 Pleural Neoplasms Cisplatin 4.8117638057
MESH:D010998 Pleurisy Carrageenan 6.2219934399
MESH:D011014 Pneumonia Lipopolysaccharides 9.3811605937 12224865
MESH:D011014 Pneumonia Ozone 9.3818007984 18929643 18381685
MESH:D011041 Poisoning Mustard Gas 3.3315727166
MESH:D017119 Porphyria Cutanea Tarda Hexachlorobenzene 9.479918132
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 9.4718163543
MESH:D011230 Precancerous Conditions Cyclosporine 18.2912371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 18.292563599
MESH:D011230 Precancerous Conditions Phenobarbital 18.292563599
MESH:D011230 Precancerous Conditions Quercetin 18.2919056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.2421297632
MESH:D011225 Pre-Eclampsia Zinc 3.7717114810
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 13.3217132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 13.3211222880 11118676 11896295 11399792
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 13.3218220299 19015723 18042343
MESH:D011469 Prostatic Diseases vinclozolin 4.4218220299
MESH:D011471 Prostatic Neoplasms marker/mechanism 17566973
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.7119131511
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.7119082440 18626508
MESH:D011471 Prostatic Neoplasms Flurbiprofen 2.7117409433
MESH:D011471 Prostatic Neoplasms Ibuprofen 2.7117409433
MESH:D011471 Prostatic Neoplasms Paclitaxel 2.7117136230 17172428 16729912 16356831
MESH:D011471 Prostatic Neoplasms Quercetin 2.7114715546 17292933
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.7116039940
MESH:D011471 Prostatic Neoplasms Sodium Selenite 2.7118760546
MESH:D011471 Prostatic Neoplasms Zinc 2.7116517595 16700911 12429649 16606632
MESH:D011472 Prostatitis vinclozolin 4.4218629315
MESH:D011507 Proteinuria Ibuprofen 7.926375363
MESH:D011507 Proteinuria Tretinoin 7.9216636307
MESH:D011537 Pruritus Ethinyl Estradiol 7.8116919318 15861022
MESH:D011537 Pruritus Mustard Gas 7.8118058305
MESH:D019310 Pseudolymphoma Phenobarbital 3.9712752131
MESH:D011565 Psoriasis Cyclosporine 2.0316882103
MESH:D011625 Pterygium Tretinoin 4.2716723453
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 4.8014606601
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.7117620002 17894541 10334151 17720292 17266442
MESH:D012004 Rectal Neoplasms Fluorouracil 3.5718722050 15538739 16160472 18286688
MESH:D051437 Renal Insufficiency Cisplatin 3.9015464296
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 3.5418379247 11700416
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.3810835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.3418990726
MESH:D012162 Retinal Degeneration Zinc 3.7316584753
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 3.1516849425
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.6216116481 16283617
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 8.7116646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 8.7114601052
MESH:D012554 Schistosomiasis japonica Quercetin 5.0216862918
MESH:D012640 Seizures 2,6-dinitrotoluene 7.8018551238
MESH:D012640 Seizures Ethanol 7.809754883
MESH:D012640 Seizures Phenobarbital 7.804039156 3137016 16876388 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 4.306407741
MESH:D018805 Sepsis Zymosan 4.2211441115
MESH:D012871 Skin Diseases Ascorbic Acid 4.7718709164
MESH:D012871 Skin Diseases Mustard Gas 4.7715451306 12880345 16961503
MESH:D012878 Skin Neoplasms sodium arsenite 7.8718572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 7.8716192470
MESH:D012878 Skin Neoplasms Tretinoin 7.8716467112
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.8115464296
MESH:D013088 Spermatocele Ethinyl Estradiol 3.4116709447
MESH:D016135 Spinal Dysraphism sodium arsenite 3.3912854658
MESH:D013272 Stomach Diseases therapeutic 15472012
MESH:D013272 Stomach Diseases Dexamethasone 3.8115472012
MESH:D013274 Stomach Neoplasms arsenic trioxide 11.3617007042
MESH:D013274 Stomach Neoplasms Cisplatin 11.3618396642 15958060 17522103
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 11.3618456281
MESH:D013274 Stomach Neoplasms Ethanol 11.3618456281
MESH:D013274 Stomach Neoplasms Fluorouracil 11.3616424979 17522103 17498489 18567086 17172411 18396642 19015929 19084572 15786421 16951190
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 11.3617575124 12958204
MESH:D013274 Stomach Neoplasms Paclitaxel 11.3618396642 18506536
MESH:D013274 Stomach Neoplasms Tretinoin 11.3617261132
MESH:D013276 Stomach Ulcer Ascorbic Acid 9.5918726076
MESH:D013276 Stomach Ulcer Dexamethasone 9.5915138204
MESH:D013276 Stomach Ulcer Ethanol 9.599211565 17918041 9562338 16755016 17189318 11906479
MESH:D020521 Stroke Ascorbic Acid 3.8816517955 16403987
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.809754883
MESH:D024801 Tauopathies Paclitaxel 4.2916930453
MESH:D013736 Testicular Neoplasms Cisplatin 4.1517225452 15464296
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.7115821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.1411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7215669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.3712697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 13.8319014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 13.837505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 13.831399818
MESH:D013964 Thyroid Neoplasms Tretinoin 13.8316026305 17045167
MESH:D014062 Tongue Neoplasms Fluorouracil 14.0016280240
MESH:D014062 Tongue Neoplasms Tretinoin 14.0016051514
MESH:D014062 Tongue Neoplasms Zinc 14.0016543248
MESH:D016171 Torsades de Pointes arsenic trioxide 3.4515213294
MESH:D014376 Tuberculosis Tretinoin 2.8916040207
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 13.3616049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 13.3611780464 20435036 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 13.3615464296 17225452 12973940
MESH:D001749 Urinary Bladder Neoplasms Quercetin 13.3616720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 13.3617306315 16712894 16452187 11723127
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.8010091137
MESH:D014581 Urticaria Acetaminophen 2.5010982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 18.9416803524
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 18.9416803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 18.9411813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 18.9416129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.8114692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.0816752155
MESH:D014605 Uveitis Cyclosporine 17.251336536
MESH:D014605 Uveitis Dexamethasone 17.251336536
MESH:D014605 Uveitis Zymosan 17.2511006244
MESH:D014625 Vaginal Neoplasms Cisplatin 4.1015577323
MESH:D014652 Vascular Diseases sodium arsenite 3.9117056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.0712125929
MESH:D020301 Vasospasm, Intracranial Ibuprofen 4.6719057314
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.0714671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.5616761959
MESH:D014839 Vomiting Cisplatin 4.1911897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.7215886252
MESH:D009396 Wilms Tumor Tretinoin 3.5316287080
MESH:D014985 Xerophthalmia Cyclosporine 3.9117120751
Pathway ID Pathway Name
REACT:14797 Signaling by GPCR
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA24823
    • No data
    No data
    Releated drug ID Related drug Name
    PA448547beclomethasone
    PA164754818betamethasone
    PA448681budesonide
    PA164781399ciclesonide
    PA164776996desonide
    PA449247dexamethasone
    PA449661flunisolide
    PA449686fluticasone propionate
    PA452347glucocorticoids
    PA449905hydrocortisone
    PA448478l-arginine
    PA164747225l-citrulline
    PA450466methylprednisolone
    PA450541mometasone
    PA450635nitric oxide
    PA164777035paramethasone
    PA451096prednisolone
    PA451100prednisone
    PA164752251rimexolone
    PA451749triamcinolone
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00288 agonist Amcinonide Corticosteroids, topical
    DB00741 agonist Vosol Hc Anti-inflammatory Agents
    DB01234 stimulator Tresaderm Dermatologic Solution Anti-inflammatory Agents;Adrenergic Agents;Antiemetics;Antineoplastic Agents, Hormonal;Glucocorticoids
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved