AutismKB 2.0

Annotation Detail for HIST1H1A


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Basic Information Top
Gene Symbol:HIST1H1A ( H1.1,H1A,H1F1,HIST1,MGC126642,MGC138345 )
Gene Full Name: histone cluster 1, H1a
Band: 6p22.2
Quick LinksEntrez ID:3024; OMIM: 142709; Uniprot ID:H11_HUMAN; ENSEMBL ID: ENSG00000124610; HGNC ID: 4715
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001104 Arbutin Arbutin results in increased expression of HIST1H1A mRNAincreases expression 17103032
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of HIST1H1A mRNAincreases expression 20504355
C011890 kojic acid kojic acid results in increased expression of HIST1H1A mRNAincreases expression 16595896
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0620464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 2.886695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.7319183758
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9920146248 17474063
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1420419170
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0916530937
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8520471113
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 2.1720195826 21137059
MESH:D008114 Liver Neoplasms, Experimental kojic acid 3.5818544905
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5718569708 20135361 20464547 20869020 18816296 17053015 18520028 20064080 6695378
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5316381670
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3511141357
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9017292933
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5419755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.3117053015
Pathway ID Pathway Name
REACT:578 Apoptosis
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018