AutismKB 2.0

Annotation Detail for HELLS


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Basic Information Top
Gene Symbol:HELLS ( FLJ10339,LSH,PASG,SMARCA6 )
Gene Full Name: helicase, lymphoid-specific
Band: 10q23.33
Quick LinksEntrez ID:3070; OMIM: 603946; Uniprot ID:HELLS_HUMAN; ENSEMBL ID: ENSG00000119969; HGNC ID: 4861
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
P00057Wnt signaling pathway
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of HELLS proteinaffects expression 20106945
C447119 bazedoxifene acetate bazedoxifene acetate results in decreased expression of HELLS mRNAdecreases expression 19914376
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of HELLS mRNAincreases expression 20504355
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of HELLS mRNAdecreases expression 20382639
20018196
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of HELLS mRNAaffects expression 17484886
D016572 Cyclosporine Cyclosporine results in decreased expression of HELLS mRNAdecreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of HELLS mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HELLS mRNAaffects cotreatment|increases expression 17942748
D005480 Flurbiprofen Flurbiprofen results in increased expression of HELLS mRNAincreases expression 16949054
C051890 irinotecan irinotecan analog results in decreased expression of HELLS mRNAdecreases expression 18927307
D010126 Ozone TTPA protein affects the reaction [Ozone results in increased expression of HELLS mRNA]affects reaction|increases expression 19555225
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of HELLS mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital affects the expression of HELLS mRNAaffects expression 19136022
D010634 Phenobarbital Phenobarbital results in increased expression of HELLS mRNAincreases expression 19482888
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of HELLS mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid affects the expression of HELLS mRNAaffects expression 19136022
D011374 Progesterone Progesterone results in decreased expression of HELLS mRNAdecreases expression 16966611
C059514 resveratrol resveratrol results in decreased expression of HELLS mRNAdecreases expression 15767336
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of HELLS mRNAdecreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HELLS mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of HELLS mRNAincreases expression 17942748
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 8.466195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.4615322242 14514962 11752688
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0017505938
MESH:D058186 Acute Kidney Injury resveratrol 3.8816538975
MESH:D055371 Acute Lung Injury pirinixic acid 3.1518653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.2020127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.2014692618
MESH:D000236 Adenoma Benzo(a)pyrene 6.866695378
MESH:D000236 Adenoma resveratrol 6.8615688382
MESH:D018248 Adenoma, Liver Cell Phenobarbital 17.6017620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 17.6016434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 17.6016835633
MESH:D011125 Adenomatous Polyposis Coli Flurbiprofen 5.0910680582
MESH:D000544 Alzheimer Disease Ozone 4.4015513908
MESH:D000544 Alzheimer Disease resveratrol 4.4016162502 16183991
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9711748828
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.1219183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.4215885639
MESH:D001169 Arthritis, Experimental resveratrol 7.4217115116
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5615570426
MESH:D001249 Asthma Ozone 2.6417854713 16373670
MESH:D050197 Atherosclerosis resveratrol 3.2917967414 16873680
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.8619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.8612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7815746008
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.4017868700
MESH:D001930 Brain Injuries Progesterone 4.3015665606 15380490 15845082
MESH:D002545 Brain Ischemia resveratrol 4.3317600658
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9620146248 17474063
MESH:D001943 Breast Neoplasms Progesterone 1.9616175315 15562024 17614352
MESH:D001943 Breast Neoplasms resveratrol 1.9616393696 17651959 17534123
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9620435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.7018417511 16777450 18315731 17626835 15516495 14754758 19059883
MESH:D002100 Cachexia Ozone 4.7916183385
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.8215673190 16011737 16227642 16192424 15700767 18705752 15721981 16124888 10355542 16097048 3786805 16050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8216835633
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 6.6512907637 21507988 12619106
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 6.6518788625
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 6.6520007298 17173139 6705139 1701930 20935162
MESH:D006528 Carcinoma, Hepatocellular resveratrol 6.6519321006 16227395
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.6416675471
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.7520419170
MESH:D002294 Carcinoma, Squamous Cell resveratrol 4.7516227395
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3818850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases resveratrol 3.4915458977
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.6220889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.6212371664
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.294080065
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1916835633
MESH:D002779 Cholestasis Cyclosporine 13.4719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.4717681005 17110522 16919318 15861022 16105132 17333356 11677210
MESH:D002779 Cholestasis pirinixic acid 13.4719176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1112621046 8697196 15668235 15340226 16354765
MESH:D003092 Colitis resveratrol 4.1716474422
MESH:D003110 Colonic Neoplasms irinotecan 4.0617725105 17287894
MESH:D003110 Colonic Neoplasms resveratrol 4.0616338953
MESH:D015179 Colorectal Neoplasms irinotecan 2.8218509181 18259882 15273666 16391804 16303861 17159606 17454858
MESH:D015179 Colorectal Neoplasms resveratrol 2.8216550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0817141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.7716507316
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2515322242 10048152 20055451
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4418249437
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.7916873680
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6717107852
MESH:D003928 Diabetic Nephropathies resveratrol 3.9916286809
MESH:D003929 Diabetic Neuropathies Progesterone 4.5317187935
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 3.7519085960 11566570 17522070 6623471 15968718 10092053 4309450 3786805 16177239 15998439 16227642 6884620 7440962 15027814 2869522 7120509 9327722 7179309 21278145 19336974 10915739 3732212
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.7520420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7811462148
MESH:D004421 Dystonia Phenobarbital 4.041851702
MESH:D004487 Edema pirinixic acid 11.6012083418
MESH:D004487 Edema resveratrol 11.608985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.6012711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9615322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.6112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 15.6117692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 15.6117872969
MESH:D004715 Endometriosis Progesterone 9.0216134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 9.0210568697 9294722
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.8917923197
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.153659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.9311558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.9020417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.576401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.297750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.073659116
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.3720426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.3716530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0311564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 18.9917595544 15959796 19224547 12631006 61145 12795759 16045604 16239168
MESH:D005234 Fatty Liver Cyclosporine 18.9919224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 18.9915345470
MESH:D005234 Fatty Liver pirinixic acid 18.9920131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5011858732
MESH:D005355 Fibrosis Carbon Tetrachloride 14.9718705752
MESH:D005355 Fibrosis Cyclosporine 14.9712639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.9720067830
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.278708960
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6610696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.4920471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.4910048152 11294989
MESH:D006333 Heart Failure pirinixic acid 2.5520558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.4715720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3611000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.6319900420 19110552
MESH:D006529 Hepatomegaly Phenobarbital 14.6416109766
MESH:D006529 Hepatomegaly pirinixic acid 14.6419176532 16221962 19772884 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 14.6416120746 15340226 12621046
MESH:D006561 Herpes Simplex resveratrol 4.2316876885
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1116959395 8697196 16354765 15340226 18606429
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.5816899240
MESH:D006937 Hypercholesterolemia resveratrol 4.0317188708
MESH:D006943 Hyperglycemia pirinixic acid 3.2120558911
MESH:D006949 Hyperlipidemias resveratrol 4.0616873680
MESH:D006973 Hypertension Cyclosporine 4.9810903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.9818850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.1315338365
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.3317488730
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8516945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 11.6315869954
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 11.6317600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5017937319
MESH:D007249 Inflammation Flurbiprofen 12.1711099482
MESH:D007249 Inflammation Progesterone 12.1715869954
MESH:D007249 Inflammation resveratrol 12.1716366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 12.1712878042 12200463
MESH:D007251 Influenza, Human resveratrol 4.6116624496
MESH:D007333 Insulin Resistance pirinixic acid 2.6516306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3616580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.5015604871
MESH:D007674 Kidney Diseases Cyclosporine 2.358314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 2.7612371664
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.5916087638
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.6811408273 11903743 16943688 17157831 17174718 17334410 16239168 16221502 21278145
MESH:D008103 Liver Cirrhosis Phenobarbital 6.6821047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 3.4012389079 13678700 16638106 14724832 14748882 12667390 17698563 15650968 17922224 12609069 15338365 18705752 18054572 17944888 18472094 12958196 17805973 17565644 18210741 18205269 16248980 17640975 17714472 15052691 16136751 18418968 16015684 18472332 17708605 18481824 12445418 18420326 18277467 12445421 18251166 17976157 18376398 15123356 15673190 17900296 17823541 17481882 12666154 12586293 15370692 16033810 14512876 18429990 14716496 12741479 15730626 18339082 17761835 17766677 15925388 16116963 12649538 18279442 15931870 15959796 14620537 18156304 12632514 18395095 18006644 18166357 15818738 10355542 18412020 17721639 17557913 11481614 18395914 15057751 12546737 16027843 12898905 15893842 18317297 18263696 20821823 15362042 17525996 16192424 17869086 15876570 16097048 16011737 15996030 12632512 17631135 18187930 14716833
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.4015474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.4012878042
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.1216246199 17285989 15720792 16964402 15830285
MESH:D008107 Liver Diseases Phenobarbital 4.1219363144
MESH:D017093 Liver Failure Carbon Tetrachloride 4.2115123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.7216899240 14706259
MESH:D008113 Liver Neoplasms Aflatoxin B1 22.092125692 15890375 9163691 18177683
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 22.0921137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 22.0919294768
MESH:D008113 Liver Neoplasms Phenobarbital 22.0915975961 19812893 8742319 21047994 19482888 19073162
MESH:D008113 Liver Neoplasms pirinixic acid 22.0920007298 16377806 15890375
MESH:D008113 Liver Neoplasms resveratrol 22.0919812893 19321006 20405173 19073162
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 22.0916984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 14.268603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 14.2615583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 14.2618308698 1399818 6150874 17172636 2563599
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 14.2612151625
MESH:D008171 Lung Diseases Ozone 3.3919066396 8266340
MESH:D055370 Lung Injury Ozone 3.8920417186
MESH:D008175 Lung Neoplasms Aflatoxin B1 4.8714755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 4.8718569708 20135361 20464547 6695378 18520028 20869020 18816296 17053015 20064080
MESH:D008175 Lung Neoplasms Ozone 4.878597069 7614698
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8719555203 11884234
MESH:D016393 Lymphoma, B-Cell resveratrol 4.3317088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.8914749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.3015688416
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 6.3211408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 6.3211606380 8985016
MESH:D008545 Melanoma resveratrol 2.3717992120
MESH:D008659 Metabolic Diseases resveratrol 4.4117112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.8516801185
MESH:D008679 Metaplasia Ozone 5.1710496685
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.2116381670
MESH:D052016 Mucositis irinotecan 5.0617159606
MESH:D009101 Multiple Myeloma resveratrol 3.4916490592 16267019 17049120 17164350 14749477 17935668
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.9217962980
MESH:D009135 Muscular Diseases pirinixic acid 3.5516239165
MESH:D009203 Myocardial Infarction pirinixic acid 5.7819151258
MESH:D009203 Myocardial Infarction resveratrol 5.7817188708 16456233 16525036 17015251 17125593 16317513
MESH:D017202 Myocardial Ischemia resveratrol 9.0817015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 9.0812213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9716411023
MESH:D009205 Myocarditis resveratrol 4.8117322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.5317484760
MESH:D009362 Neoplasm Metastasis irinotecan 3.1818259882
MESH:D009369 Neoplasms Benzo(a)pyrene 4.8611141357
MESH:D009369 Neoplasms pirinixic acid 4.8617405874
MESH:D009374 Neoplasms, Experimental resveratrol 4.048985016
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.5017954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.3119348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.2514600291
MESH:D009447 Neuroblastoma irinotecan 3.498761367
MESH:D019636 Neurodegenerative Diseases resveratrol 3.8317652729
MESH:D017599 Neuroectodermal Tumors irinotecan 4.788761367
MESH:D020078 Neurogenic Inflammation resveratrol 4.4317929310
MESH:D009765 Obesity pirinixic acid 1.8220558911
MESH:D010018 Osteomalacia Phenobarbital 4.4117016548
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.2917513867
MESH:D010051 Ovarian Neoplasms Progesterone 2.5316525653 17393432
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.5016965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7211578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3112520081
MESH:D010538 Peritonitis Ozone 4.1716369182
MESH:D011014 Pneumonia Ozone 4.4418007984 18929643 18381685
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5918163543
MESH:D011230 Precancerous Conditions Cyclosporine 9.0512371664
MESH:D011230 Precancerous Conditions Phenobarbital 9.052563599
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 9.7616679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.7611222880 11896295 11118676 11399792
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.7717292933
MESH:D011471 Prostatic Neoplasms Flurbiprofen 2.7717409433
MESH:D011471 Prostatic Neoplasms resveratrol 2.7717675339 15767336 17636462 16731767 17804756 17718901
MESH:D011537 Pruritus Ethinyl Estradiol 3.3616919318 15861022
MESH:D019310 Pseudolymphoma Phenobarbital 4.5612752131
MESH:D011565 Psoriasis Cyclosporine 2.2416882103
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.6516325855
MESH:D015427 Reperfusion Injury pirinixic acid 6.6119058328
MESH:D015427 Reperfusion Injury resveratrol 6.6116314181 15827377 17058453 17520802 16317513
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8718990726
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.8618045962
MESH:D012640 Seizures Phenobarbital 2.713137016 11442880 16876388 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 4.876407741
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 9.5219755658 10029692
MESH:D012878 Skin Neoplasms resveratrol 9.528985016 15837718
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.5216192470
MESH:D013088 Spermatocele Ethinyl Estradiol 4.0016709447
MESH:D013119 Spinal Cord Injuries Progesterone 4.3315862959 16503802
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.562093021 20155912
MESH:D013274 Stomach Neoplasms irinotecan 2.5615723263
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.5116321402
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9612697716
MESH:D013964 Thyroid Neoplasms Phenobarbital 3.071399818
MESH:D014062 Tongue Neoplasms resveratrol 4.2416227395
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.1917053015
MESH:D002583 Uterine Cervical Neoplasms resveratrol 4.1317473185
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.6214692618
MESH:D014594 Uterine Neoplasms resveratrol 9.6217044934
MESH:D014605 Uveitis Cyclosporine 4.051336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5714671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.3417488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3115886252
MESH:D014985 Xerophthalmia Cyclosporine 4.5017120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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