AutismKB 2.0

Annotation Detail for CXXC1


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Basic Information Top
Gene Symbol:CXXC1 ( 2410002I16Rik,5830420C16Rik,CFP1,CGBP,HsT2645,PCCX1,PHF18,SPP1,ZCGPC1,hCGBP )
Gene Full Name: CXXC finger protein 1
Band: 18q21.1
Quick LinksEntrez ID:30827; OMIM: 609150; Uniprot ID:CXXC1_HUMAN; ENSEMBL ID: ENSG00000154832; HGNC ID: 24343
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
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Pathway IDPathway Name
Diabetes pathways
No data
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No data
Related Diseases/Disorders Top
No data
No data
Desease Name
CANCER
Chronic lymphocytic leukemia
Desease Name
Chronic lymphocytic leukemia
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of CXXC1 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of CXXC1 mRNAaffects expression 17562736
D012643 Selenium Selenium results in increased expression of CXXC1 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 2.9716705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.973084413
MESH:D002386 Cataract Acetaminophen 2.8110977129
MESH:D003092 Colitis Selenium 4.4317936198
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.6718551238
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 6.8018551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.8012540782 12705907 16485898 15968718 15619225 12958197 19739265 14725611 17906064 16781746 19923254 17522070 12594235 11421492 18713872 18071297 10663392 11461765 14550746 19416960 19164858 16109766 11743745 17562736 19420014 14986274 11287661 19085960 11739529 11834606 11529661 16081117 10915739 16177239 2444490 12392966 12153990 19370779 10774834 16227642 16393943
MESH:D056486 Drug-Induced Liver Injury Selenium 6.8015131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D006333 Heart Failure Selenium 3.3217162251
MESH:D006930 Hyperalgesia Acetaminophen 3.0616870215
MESH:D007251 Influenza, Human Selenium 5.0616624496
MESH:D007674 Kidney Diseases Acetaminophen 2.4215629191 12587719
MESH:D007676 Kidney Failure, Chronic Selenium 4.3716518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 3.3616705839
MESH:D008107 Liver Diseases Acetaminophen 1.7119014921 12969438 19460945 16611625 12587719 16610002 19784758 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6816871587 17185352
MESH:D008325 Mammary Neoplasms, Experimental Selenium 3.0215318939
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D008654 Mesothelioma Selenium 2.9315107826
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.6018551238
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.8812819281 16049721
MESH:D010146 Pain Acetaminophen 2.7716870215
MESH:D010954 Plasmacytoma Selenium 5.7615087411
MESH:D012640 Seizures 2,4-dinitrotoluene 2.8118551238
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.4216049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 5.0610091137
MESH:D014581 Urticaria Acetaminophen 3.5010982225
Pathway ID Pathway Name
REACT:15380 Diabetes pathways
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018