AutismKB 2.0

Annotation Detail for HK2


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Basic Information Top
Gene Symbol:HK2 ( DKFZp686M1669,HKII,HXK2 )
Gene Full Name: hexokinase 2
Band: 2p12
Quick LinksEntrez ID:3099; OMIM: 601125; Uniprot ID:HXK2_HUMAN; ENSEMBL ID: ENSG00000159399; HGNC ID: 4923
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-842starch degradation
Pathway IDPathway Name
hsa04973Carbohydrate digestion and absorption
hsa04910Insulin signaling pathway
hsa00010Glycolysis / Gluconeogenesis
hsa00524Butirosin and neomycin biosynthesis
hsa00520Amino sugar and nucleotide sugar metabolism
hsa01100Metabolic pathways
hsa00052Galactose metabolism
hsa00051Fructose and mannose metabolism
hsa00500Starch and sucrose metabolism
hsa04930Type II diabetes mellitus
Pathway IDPathway Name
Metabolism of carbohydrates
Transmembrane transport of small molecules
Pathway IDPathway Name
200172HIF-1-alpha transcription factor network
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of HK2 mRNAincreases expression 19933214
C021296 2-ethoxyethanol 2-ethoxyethanol results in increased expression of HK2 mRNAincreases expression 19643169
D000082 Acetaminophen Acetaminophen affects the expression of HK2 mRNAaffects expression 17562736
D000111 Acetylcysteine Acetylcysteine results in increased expression of HK2 mRNAincreases expression 16084531
C430898 AGN 194204 AGN 194204 results in decreased expression of HK2 mRNAdecreases expression 16339527
D001564 Benzo(a)pyrene Benzo(a)pyrene affects the expression of HK2 mRNAaffects expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of HK2 mRNAdecreases expression 19150397
20382639
C002791 bismuth tripotassium dicitrate bismuth tripotassium dicitrate results in increased expression of HK2 mRNAincreases expression 15912405
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of HK2 mRNAaffects expression 17484886
D003035 Cobalt [tungsten carbide binds to Cobalt] which results in increased expression of HK2 mRNAaffects binding|increases expression 20105288
C018021 cobaltous chloride cobaltous chloride results in increased expression of HK2 mRNAincreases expression 20105288
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of HK2 mRNAincreases expression 17654400
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of HK2 mRNAaffects cotreatment|increases expression 16054899
D003907 Dexamethasone EGF protein inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of HK2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D003907 Dexamethasone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of HK2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D004280 Dobutamine Dobutamine results in decreased expression of HK2 proteindecreases expression 19944370
D004317 Doxorubicin Doxorubicin results in decreased expression of HK2 mRNAdecreases expression 16595493
D004317 Doxorubicin Doxorubicin results in decreased expression of HK2 proteindecreases expression 16595493
C045651 epigallocatechin gallate epigallocatechin gallate results in increased expression of HK2 mRNAincreases expression 16084531
D004958 Estradiol Estradiol results in decreased expression of HK2 mRNAdecreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of HK2 mRNAincreases expression 17606305
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HK2 mRNAaffects cotreatment|increases expression 17942748
D005472 Fluorouracil Fluorouracil results in decreased expression of HK2 proteindecreases expression 16595493
D005472 Fluorouracil HK2 protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein]affects reaction|increases activity 18772588
D005472 Fluorouracil HK2 protein affects the susceptibility to Fluorouracilaffects response to substance 18772588
D005485 Flutamide Flutamide analog results in increased expression of HK2 mRNAincreases expression 17702527
D005485 Flutamide Flutamide results in increased expression of HK2 mRNAincreases expression 17702527
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of HK2 mRNAaffects cotreatment|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine EGF protein inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of HK2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of HK2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
C005219 methyl cellosolve methyl cellosolve results in increased expression of HK2 mRNAincreases expression 19643169
C022838 nickel chloride nickel chloride results in increased expression of HK2 mRNAincreases expression 12839937
C006253 pirinixic acid pirinixic acid results in decreased expression of HK2 mRNAdecreases expression 17426115
C006253 pirinixic acid pirinixic acid results in increased expression of HK2 mRNAincreases expression 16985257
D011794 Quercetin Quercetin inhibits the reaction [SP1 protein promotes the reaction [AR protein results in increased expression of HK2 mRNA]]decreases reaction|increases expression|increases reaction 15661808
C059514 resveratrol resveratrol results in decreased expression of HK2 mRNAdecreases expression 16979140
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of HK2 mRNAaffects cotreatment|increases expression 16054899
C089730 rosiglitazone EGF protein inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of HK2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
C089730 rosiglitazone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of HK2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D012402 Rotenone Rotenone results in increased expression of HK2 mRNAincreases expression 17702527
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of HK2 mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HK2 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of HK2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of HK2 mRNAincreases expression 17942748
17035482
19933214
C496197 trans-10,cis-12-conjugated linoleic acid trans-10,cis-12-conjugated linoleic acid results in increased expression of HK2 mRNAincreases expression 17951470
C002802 tungsten carbide [tungsten carbide binds to Cobalt] which results in increased expression of HK2 mRNAaffects binding|increases expression 20105288
D014415 Tunicamycin Tunicamycin results in increased expression of HK2 mRNAincreases expression 17127020
D014638 Vanadates Vanadates results in increased expression of HK2 proteinincreases expression 17874149
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 2-ethoxyethanol 12.646499796 6499812 7151721 6499820 6499823
MESH:D000014 Abnormalities, Drug-Induced methyl cellosolve 12.643652986 6499812 6474471
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 12.6415322242 14514962 11752688
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6117505938
MESH:D058186 Acute Kidney Injury resveratrol 3.5616538975
MESH:D055371 Acute Lung Injury pirinixic acid 2.8218653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 12.5820127859 20464547
MESH:D000230 Adenocarcinoma Doxorubicin 12.5817418594
MESH:D000230 Adenocarcinoma Estradiol 12.5811473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 12.5814692618
MESH:D000230 Adenocarcinoma Fluorouracil 12.5817638652
MESH:D000236 Adenoma Benzo(a)pyrene 6.176695378
MESH:D000236 Adenoma resveratrol 6.1715688382
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.8216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.8216835633
MESH:D000419 Albuminuria Doxorubicin 4.2321441931
MESH:D000544 Alzheimer Disease resveratrol 4.2616162502 16183991
MESH:D000544 Alzheimer Disease rosiglitazone 4.2619621015
MESH:D000740 Anemia Fluorouracil 7.7517963324 15504547 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.7511748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.9517084956
MESH:D000748 Anemia, Macrocytic methyl cellosolve 6.023699323
MESH:D000799 Angioedema Acetaminophen 3.5110982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.7619183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1511256880
MESH:D001169 Arthritis, Experimental Dexamethasone 11.1717659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 11.1715885639
MESH:D001169 Arthritis, Experimental resveratrol 11.1717115116
MESH:D053627 Asthenozoospermia 2-ethoxyethanol 11.5210689203 6499807 6499823
MESH:D053627 Asthenozoospermia methyl cellosolve 11.523987992
MESH:D001249 Asthma epigallocatechin gallate 3.2916516891
MESH:D001259 Ataxia 2-ethoxyethanol 5.157151721
MESH:D001260 Ataxia Telangiectasia Quercetin 4.6515336622
MESH:D050197 Atherosclerosis resveratrol 3.0816873680 17967414
MESH:D001284 Atrophy 2-ethoxyethanol 10.386499799 15850284
MESH:D001284 Atrophy methyl cellosolve 10.386705890 3699323 2626667
MESH:D001321 Autistic Disorder Acetaminophen 1.4518445737
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 10.0219761891
MESH:D001327 Autoimmune Diseases Quercetin 10.0219761891
MESH:D053713 Azoospermia 2-ethoxyethanol 5.266499807 6492198
MESH:D001724 Birth Weight 2-ethoxyethanol 6.186499823 2884743
MESH:D001778 Blood Coagulation Disorders pirinixic acid 7.8019483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 7.8012125929
MESH:D001836 Body Weight Changes 2-ethoxyethanol 10.927151721 6499796
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 10.9215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5615746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.3714601052
MESH:D002545 Brain Ischemia resveratrol 3.9617600658
MESH:D001932 Brain Neoplasms Doxorubicin 3.5317150277
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 4.4417474063 20146248
MESH:D001943 Breast Neoplasms Cobalt 4.4415986119
MESH:D001943 Breast Neoplasms Doxorubicin 4.4417369602 19526202 11325840 15136595 17983394 16096432 16115903 16264153 18234424 18628466 15634643 18695136 15993339 15939500 16322301 17426702 16826403 16935488 15692762 15994142 15668708 18382427 16595493 15567936
MESH:D001943 Breast Neoplasms Estradiol 4.4417289903 14630087 12948864 16675129 18497071 17261762 17018787 19861407
MESH:D001943 Breast Neoplasms Fluorouracil 4.4418608205 16110121 16557594 19217205 18357371 15136595 16595493
MESH:D001943 Breast Neoplasms Quercetin 4.4418628248
MESH:D001943 Breast Neoplasms resveratrol 4.4417534123 17651959 16393696
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 4.4420435547
MESH:D002105 Cadmium Poisoning Quercetin 5.2116962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1416111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.4615721981 16011737 15700767 16050911 16227642 16097048 3786805 10355542 15673190 16124888 16192424 18705752
MESH:D002276 Carcinoid Tumor Doxorubicin 11.2516051944
MESH:D002276 Carcinoid Tumor Fluorouracil 11.2516051944
MESH:D002277 Carcinoma Fluorouracil 7.3417121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.3416835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 13.183084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 13.1818788625
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 13.1816234567 18059187 16023760 17876044
MESH:D006528 Carcinoma, Hepatocellular Estradiol 13.1816924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 13.1816332177 16799960 17045692 17971768 17088986 18930000
MESH:D006528 Carcinoma, Hepatocellular Quercetin 13.1812508355 19519916
MESH:D006528 Carcinoma, Hepatocellular resveratrol 13.1816227395 19321006
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.2716675471
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.6417234771
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.151485588 16201981
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 6.1518695887
MESH:D002294 Carcinoma, Squamous Cell Acetylcysteine 13.2717015178
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 13.2720419170
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 13.276189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 13.2716757204 18986760 17066447 16280240
MESH:D002294 Carcinoma, Squamous Cell resveratrol 13.2716227395
MESH:D006332 Cardiomegaly Quercetin 6.2019794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.2018670907 16120746 18850075
MESH:D009202 Cardiomyopathies Doxorubicin 3.3217928571 17329180 16242529 17131338 17007740 15505089 15811867 16109756 15792986 17519947 17924179 15476868 17382496 16364871 16952015 17308081 16455267 17351982 17974986 16651473 16612575 18627295 16278810 16269455 16731534
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8316243910 17334414
MESH:D002318 Cardiovascular Diseases resveratrol 3.2515458977
MESH:D002386 Cataract Acetaminophen 2.3910977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.0220889678
MESH:D002471 Cell Transformation, Neoplastic Acetylcysteine 10.0218226522
MESH:D002471 Cell Transformation, Neoplastic Estradiol 10.0218566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.8916835633
MESH:D002764 Cholecystitis 2-ethoxyethanol 12.556499794
MESH:D002764 Cholecystitis methyl cellosolve 12.556499794
MESH:D002779 Cholestasis Ethinyl Estradiol 6.9517681005 17110522 16919318 11677210 16105132 15861022 17333356
MESH:D002779 Cholestasis pirinixic acid 6.9519176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.9715668235 15340226 16354765 8697196 12621046
MESH:D003092 Colitis resveratrol 3.8116474422
MESH:D003110 Colonic Neoplasms Dexamethasone 7.7815824018
MESH:D003110 Colonic Neoplasms Fluorouracil 7.7818772588 17725105 17169374 16510598 17172411 17287894 17018589 17016597 15001691 16340194
MESH:D003110 Colonic Neoplasms Quercetin 7.7811134977 17191121 19440933 19056647 17148506 16640504 15741050
MESH:D003110 Colonic Neoplasms resveratrol 7.7816338953
MESH:D015179 Colorectal Neoplasms Doxorubicin 4.5518259882 18802399
MESH:D015179 Colorectal Neoplasms Fluorouracil 4.5515289873 17454858 17594712 17401013 18949393 15148649 17255274 17695437 14970324 18802399 18288408 16303861 18448328 16331619 17094418 17016601 16391804 18383874 16524972 18509181 16282729 20501625
MESH:D015179 Colorectal Neoplasms Quercetin 4.5518852136 18095365
MESH:D015179 Colorectal Neoplasms resveratrol 4.5516550006
MESH:D000013 Congenital Abnormalities methyl cellosolve 8.5212530607 6499821
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.5217141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.5416507316
MESH:D019465 Craniofacial Abnormalities Dexamethasone 2.5117728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.5110048152 15322242 20055451
MESH:D003550 Cystic Fibrosis Acetylcysteine 4.1019747007
MESH:D007644 Darier Disease Fluorouracil 4.4716733453
MESH:D003643 Death 2-ethoxyethanol 5.636499796
MESH:D017449 Dermatitis, Allergic Contact cobaltous chloride 6.4615059100 16823706 11298694
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 6.4612438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2718249437
MESH:D003920 Diabetes Mellitus rosiglitazone 4.0317446233
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 7.6819496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 7.6816873680
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 6.8016988119
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 6.8012642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.8017107852
MESH:D003928 Diabetic Nephropathies Estradiol 8.1219279558
MESH:D003928 Diabetic Nephropathies resveratrol 8.1216286809
MESH:D003967 Diarrhea Dexamethasone 3.407237001
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 13.9114986274 12594235 11287661 19923254 16227642 14550746 19085960 12392966 11834606 10663392 18071297 11529661 17906064 19370779 15968718 16393943 11421492 16177239 11461765 11739529 10915739 10774834 17522070 19420014 12705907 11743745 16109766 2444490 12958197 16485898 19416960 15619225 16081117 18713872 14725611 12153990 16781746 19164858 19739265 12540782 17562736
MESH:D056486 Drug-Induced Liver Injury Acetylcysteine 13.9111287661
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 13.913786805 2869522 11566570 21278145 10092053 10915739 3732212 7440962 7179309 16177239 19336974 19085960 15998439 16227642 15027814 4309450 7120509 9327722 6623471 15968718 6884620 17522070
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 13.9117654400
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 13.9117416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 13.9120420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.7719426721
MESH:D004362 Drug Toxicity Doxorubicin 7.3218602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.3211462148
MESH:D004485 Eczema Dexamethasone 4.1512438553
MESH:D004487 Edema Dexamethasone 18.5919703484
MESH:D004487 Edema pirinixic acid 18.5912083418
MESH:D004487 Edema resveratrol 18.598985016
MESH:D004487 Edema rosiglitazone 18.5912083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 18.5912711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.5715322242 18230668 16714409
MESH:D020964 Embryo Loss 2-ethoxyethanol 6.186499796
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.1012538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 8.1017872969
MESH:D016889 Endometrial Neoplasms Doxorubicin 6.8317359293
MESH:D016889 Endometrial Neoplasms Estradiol 6.8318566989 11473722 19148513
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.749294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.8318037988
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.5317923197
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.6920426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 6.6916530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 6.6916337965 16785472 15173087 17638652 16481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.7711564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 16.4012631006 16239168 12795759 16045604 15959796 61145 17595544 19224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 16.4015345470
MESH:D005234 Fatty Liver pirinixic acid 16.4020131406 19236843
MESH:D005234 Fatty Liver rosiglitazone 16.4019196556
MESH:D005313 Fetal Death 2-ethoxyethanol 9.787151721 6499820 7198755 2884743 6499823
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 9.7811858732
MESH:D005317 Fetal Growth Retardation 2-ethoxyethanol 5.106499796
MESH:D005327 Fetal Resorption 2-ethoxyethanol 11.576499812 6499820
MESH:D005327 Fetal Resorption methyl cellosolve 11.576499821 3987992 6474471 6499812
MESH:D020567 Fetal Weight 2-ethoxyethanol 12.557151721 6499820 2884743
MESH:D020567 Fetal Weight methyl cellosolve 12.556499821 6499812 6474471
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.2619069698
MESH:D005355 Fibrosis Carbon Tetrachloride 12.9718705752
MESH:D005355 Fibrosis Quercetin 12.9719474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 12.9720067830
MESH:D005532 Foot Deformities, Congenital methyl cellosolve 5.173652986
MESH:D005756 Gastritis Acetaminophen 3.3416983495
MESH:D005909 Glioblastoma Doxorubicin 6.6817150277
MESH:D005909 Glioblastoma Quercetin 6.6819804834
MESH:D005910 Glioma Fluorouracil 5.7416145905
MESH:D005910 Glioma Quercetin 5.7417643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2610696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 7.1915692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 7.1915162350 18337622 15102660
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 5.8720471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.8710048152 11294989
MESH:D006331 Heart Diseases Doxorubicin 3.2616144979 16879835 16244371 14766674 16707910 16495754 17888722 16244372 18674790 17875725 16330681 18006777 12587719
MESH:D006333 Heart Failure Dobutamine 10.8317440445
MESH:D006333 Heart Failure Doxorubicin 10.8317481944
MESH:D006333 Heart Failure pirinixic acid 10.8320558911
MESH:D006345 Heart Septal Defects, Ventricular methyl cellosolve 5.456499821
MESH:D006394 Hemangiosarcoma Doxorubicin 3.6115692506
MESH:D006402 Hematologic Diseases 2-ethoxyethanol 5.0910514026 20172899
MESH:D006461 Hemolysis 2-ethoxyethanol 11.2419051582 17874071
MESH:D006461 Hemolysis methyl cellosolve 11.2417874071
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0511000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.2919110552 19900420
MESH:D006529 Hepatomegaly pirinixic acid 7.2118467677 16221962 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.2115340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.957520565
MESH:D006558 Herpes Genitalis Estradiol 4.7015709030
MESH:D006561 Herpes Simplex resveratrol 3.8616876885
MESH:D006689 Hodgkin Disease Doxorubicin 3.1415147373 18501091 17606976
MESH:D019584 Hot Flashes Estradiol 3.4217088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.7115340226 18606429 8697196 16959395 16354765
MESH:D006930 Hyperalgesia Acetaminophen 7.0416870215
MESH:D006930 Hyperalgesia rosiglitazone 7.0412083418
MESH:D017588 Hyperandrogenism Flutamide 5.1315356085
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.2116899240
MESH:D006937 Hypercholesterolemia resveratrol 3.7217188708
MESH:D006943 Hyperglycemia pirinixic acid 8.3120558911
MESH:D006943 Hyperglycemia Quercetin 8.3111834736 18262572
MESH:D006949 Hyperlipidemias resveratrol 3.7316873680
MESH:D006973 Hypertension Cobalt 11.4017039479
MESH:D006973 Hypertension Dexamethasone 11.4017042910
MESH:D006973 Hypertension Quercetin 11.4018356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 11.4018850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.7715338365
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.0217488730
MESH:D007021 Hypospadias Ethinyl Estradiol 3.4916569931 16945680
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 5.1118306037
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.3317600658
MESH:D007247 Infertility, Female 2-ethoxyethanol 9.406499823
MESH:D007247 Infertility, Female Ethinyl Estradiol 9.4012013081
MESH:D007248 Infertility, Male 2-ethoxyethanol 10.266499823
MESH:D007248 Infertility, Male Ethinyl Estradiol 10.2617937319
MESH:D007248 Infertility, Male methyl cellosolve 10.263987992
MESH:D007249 Inflammation Dexamethasone 10.608960868 11099482
MESH:D007249 Inflammation resveratrol 10.6016366677
MESH:D007249 Inflammation rosiglitazone 10.6012083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 10.6012200463 12878042
MESH:D007251 Influenza, Human Quercetin 10.0916624496
MESH:D007251 Influenza, Human resveratrol 10.0916624496
MESH:D007333 Insulin Resistance Estradiol 11.1516393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 11.1516306350
MESH:D007333 Insulin Resistance rosiglitazone 11.1516306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.0516580747
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 5.1118306037
MESH:D007627 Keloid Quercetin 4.6417086741
MESH:D007674 Kidney Diseases Acetaminophen 12.9112587719 15629191
MESH:D007674 Kidney Diseases Doxorubicin 12.9115699352 16775033 15369732
MESH:D007674 Kidney Diseases Estradiol 12.9115618244
MESH:D007674 Kidney Diseases Quercetin 12.9116962696
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.8616707910
MESH:D007680 Kidney Neoplasms Estradiol 6.6215610895
MESH:D007680 Kidney Neoplasms Fluorouracil 6.6216985049
MESH:D007938 Leukemia Quercetin 2.9917468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.8316085563
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.3716087638
MESH:D017880 Limb Deformities, Congenital methyl cellosolve 4.276499821
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.6321278145 11408273 16239168 16943688 16221502 11903743 17157831 17334410 17174718
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 14.8018481824 14512876 15052691 15370692 18166357 15730626 15959796 16638106 14716833 12546737 18263696 17708605 18705752 17869086 11481614 14620537 15057751 15931870 16027843 17698563 17944888 18472094 15123356 15925388 17640975 15673190 12609069 18472332 18395095 18395914 17565644 14748882 12445421 15338365 14724832 12389079 15996030 15650968 18420326 18412020 15876570 17823541 17976157 12898905 16011737 18210741 12741479 17481882 18418968 17714472 18205269 17557913 12667390 16136751 17525996 15893842 18339082 18376398 16033810 16015684 17721639 17922224 10355542 16248980 15362042 18277467 18317297 12649538 18279442 18251166 17900296 17761835 16097048 18006644 12586293 12666154 20821823 17805973 18156304 12632514 18429990 18054572 16116963 12445418 12632512 14716496 17631135 18187930 13678700 16192424 17766677 15818738 12958196
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 14.8016718785
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 14.8016439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 14.8017481882
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 14.8014716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 14.8015474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 14.8012741479
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 14.8017347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 14.8012878042
MESH:D008107 Liver Diseases Acetaminophen 3.6012969438 12587719 19784758 11587558 19460945 16610002 19014921 16611625
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.6016246199 15720792 15830285 16964402 17285989
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8515123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.4716871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.4716899240 14706259
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 19.9121137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 19.9119294768
MESH:D008113 Liver Neoplasms Fluorouracil 19.9116603448 18383874 15113037 17045692
MESH:D008113 Liver Neoplasms pirinixic acid 19.9115890375 20007298 16377806
MESH:D008113 Liver Neoplasms Quercetin 19.9118980244
MESH:D008113 Liver Neoplasms resveratrol 19.9119321006 19812893 20405173 19073162
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 19.9116984957
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 12.4712014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 12.4716842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Quercetin 12.4719519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 12.4712151625
MESH:D008133 Long QT Syndrome Dobutamine 4.4919353679
MESH:D008171 Lung Diseases Acetylcysteine 7.5412815614
MESH:D008171 Lung Diseases Dobutamine 7.5416638327
MESH:D008173 Lung Diseases, Obstructive Cobalt 5.546434250
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 7.9717053015 18816296 6695378 20464547 20869020 18569708 20064080 18520028 20135361
MESH:D008175 Lung Neoplasms Dexamethasone 7.9711195469 15824018
MESH:D008175 Lung Neoplasms Doxorubicin 7.9717418594 6189445
MESH:D008175 Lung Neoplasms Fluorouracil 7.9715246190
MESH:D008175 Lung Neoplasms Quercetin 7.9716280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 7.9711884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.4715086387
MESH:D008223 Lymphoma Doxorubicin 3.2316098063
MESH:D016393 Lymphoma, B-Cell resveratrol 4.0017088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 8.0117654614
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 8.0114749477
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.2515621674
MESH:D008231 Lymphopenia methyl cellosolve 5.453699323
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.9215688416
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 12.6115458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 12.6116891317 11408345 11807958 17203775
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 12.6111606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 12.6116827153
MESH:D020149 Manganese Poisoning Estradiol 4.1519453300
MESH:D008545 Melanoma Doxorubicin 4.9616827129
MESH:D008545 Melanoma epigallocatechin gallate 4.9611746506 17992120
MESH:D008545 Melanoma resveratrol 4.9617992120
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2519513568
MESH:D008654 Mesothelioma Doxorubicin 2.9317638057
MESH:D008659 Metabolic Diseases resveratrol 4.0917112576
MESH:D024821 Metabolic Syndrome X rosiglitazone 4.1117261469
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.2115792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 7.7116381670
MESH:D009062 Mouth Neoplasms Fluorouracil 7.7116757204 18986760
MESH:D052016 Mucositis Doxorubicin 4.4617415656
MESH:D009101 Multiple Myeloma Dexamethasone 6.8015867202 15744524 16118317
MESH:D009101 Multiple Myeloma resveratrol 6.8017935668 16490592 17164350 17049120 14749477 16267019
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 11.5417962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 11.5417962980
MESH:D009135 Muscular Diseases pirinixic acid 3.1916239165
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 3.369809623
MESH:D009203 Myocardial Infarction Doxorubicin 12.4219429709 15857846
MESH:D009203 Myocardial Infarction pirinixic acid 12.4219151258
MESH:D009203 Myocardial Infarction Quercetin 12.4219595682
MESH:D009203 Myocardial Infarction resveratrol 12.4216317513 17188708 17015251 16525036 16456233 17125593
MESH:D017202 Myocardial Ischemia Dobutamine 13.9712447174
MESH:D017202 Myocardial Ischemia resveratrol 13.9717125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 13.9712213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.7616810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.7616411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 12.7619207477
MESH:D009205 Myocarditis resveratrol 4.4317322642
MESH:D009336 Necrosis 2-ethoxyethanol 5.0220172899
MESH:D009362 Neoplasm Metastasis Acetylcysteine 5.8014720322
MESH:D009362 Neoplasm Metastasis Doxorubicin 5.8018259882
MESH:D009369 Neoplasms Benzo(a)pyrene 10.5011141357
MESH:D009369 Neoplasms Fluorouracil 10.5018600527 16928823 18239605
MESH:D009369 Neoplasms pirinixic acid 10.5017405874
MESH:D009369 Neoplasms Quercetin 10.5015185748
MESH:D009374 Neoplasms, Experimental resveratrol 3.698985016
MESH:D009389 Neovascularization, Pathologic Estradiol 3.4117289903
MESH:D009401 Nephrosis Doxorubicin 4.4516636307 16899518
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.7315640375 16889571
MESH:D009410 Nerve Degeneration Rotenone 3.6315790535 17356569 18619942
MESH:D009421 Nervous System Malformations Estradiol 8.4416427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.4414600291
MESH:D009436 Neural Tube Defects Acetylcysteine 3.8119446573
MESH:D009447 Neuroblastoma Doxorubicin 3.0915555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.4818514411
MESH:D019636 Neurodegenerative Diseases resveratrol 7.4817652729
MESH:D020078 Neurogenic Inflammation Quercetin 9.7017929310
MESH:D020078 Neurogenic Inflammation resveratrol 9.7017929310
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.2216436463
MESH:D009765 Obesity pirinixic acid 1.7320558911
MESH:D009845 Oligospermia 2-ethoxyethanol 10.2920172899
MESH:D009845 Oligospermia methyl cellosolve 10.293987992
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 9.2019495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 9.2017513867
MESH:D012516 Osteosarcoma Doxorubicin 3.8615930896
MESH:D010051 Ovarian Neoplasms Estradiol 4.5919401270
MESH:D010051 Ovarian Neoplasms Quercetin 4.5919005980
MESH:D010146 Pain Acetaminophen 2.1416870215
MESH:D010190 Pancreatic Neoplasms Fluorouracil 5.0716929163 19003803 15113037 16500647
MESH:D010190 Pancreatic Neoplasms Quercetin 5.0716965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3911578682
MESH:D010300 Parkinson Disease Rotenone 2.8616140633 18191903 18619942 11535288 16412576 19114014 19232380 11445065 15451049
MESH:D020734 Parkinsonian Disorders Rotenone 3.8015574749 15795934 18197244 15927086
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9212520081
MESH:D003557 Phyllodes Tumor Doxorubicin 4.8317983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.8317638057
MESH:D011085 Polycystic Ovary Syndrome Flutamide 4.7215356085
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2518163543
MESH:D011230 Precancerous Conditions Quercetin 3.7119056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.3621297632
MESH:D011297 Prenatal Exposure Delayed Effects 2-ethoxyethanol 20.687198755 2884743 6499817
MESH:D011297 Prenatal Exposure Delayed Effects methyl cellosolve 20.687974496 6499817 12530607
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 20.6816679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 20.6811896295 11222880 11399792 11118676
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5920887781
MESH:D011471 Prostatic Neoplasms AGN 194204 2.3716000583
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.3717292933
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.3716888761 18437689 16868541 15897917 15749863 16729912
MESH:D011471 Prostatic Neoplasms Estradiol 2.3716740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.3718626508 19082440
MESH:D011471 Prostatic Neoplasms Flutamide 2.373169114
MESH:D011471 Prostatic Neoplasms Quercetin 2.3714715546 17292933
MESH:D011471 Prostatic Neoplasms resveratrol 2.3717804756 16731767 17675339 15767336 17636462 17718901
MESH:D011537 Pruritus Ethinyl Estradiol 2.9916919318 15861022
MESH:D011658 Pulmonary Fibrosis Cobalt 3.876434250
MESH:D012004 Rectal Neoplasms Fluorouracil 3.7415538739 16160472 18722050 18286688
MESH:D051437 Renal Insufficiency Doxorubicin 3.9017922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.2516325855
MESH:D015427 Reperfusion Injury pirinixic acid 6.0319058328
MESH:D015427 Reperfusion Injury resveratrol 6.0317520802 16314181 17058453 16317513 15827377
MESH:D012128 Respiratory Distress Syndrome, Adult Acetylcysteine 8.5012210543
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 8.5018379247 11700416
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5318990726
MESH:D012509 Sarcoma Doxorubicin 3.7117203757 15625365 15675481 16767912 18313854 17710206
MESH:D012512 Sarcoma, Ewing's Doxorubicin 3.9316326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.4617846226
MESH:D012554 Schistosomiasis japonica Quercetin 5.2116862918
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 12.2819755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 12.2815692506
MESH:D012878 Skin Neoplasms resveratrol 12.288985016 15837718
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 12.2816192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.2516767912 17203757 15625365
MESH:D013088 Spermatocele Ethinyl Estradiol 3.6116709447
MESH:D013272 Stomach Diseases Dexamethasone 4.0015472012
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.332093021 20155912
MESH:D013274 Stomach Neoplasms Fluorouracil 2.3316424979 15786421 18396642 19015929 19084572 16951190 17522103 17172411 18567086 17498489
MESH:D013276 Stomach Ulcer 2-ethoxyethanol 10.706499799
MESH:D013276 Stomach Ulcer Acetylcysteine 10.7017918041
MESH:D013276 Stomach Ulcer Dexamethasone 10.7015138204
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.2016321402
MESH:D013733 Testicular Diseases 2-ethoxyethanol 9.9810514026 6499806 10048760
MESH:D013733 Testicular Diseases methyl cellosolve 9.986499806
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5712697716
MESH:D013964 Thyroid Neoplasms Doxorubicin 3.1317909728 16010429
MESH:D013978 Tibial Fractures Estradiol 4.3519048282
MESH:D014062 Tongue Neoplasms Fluorouracil 9.0516280240
MESH:D014062 Tongue Neoplasms resveratrol 9.0516227395
MESH:D016171 Torsades de Pointes Dobutamine 5.0219353679
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 7.6217053015
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 7.6217653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 7.6216720314
MESH:D014581 Urticaria Acetaminophen 2.6810982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 8.6716803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 8.6717473185
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.4714692618
MESH:D014594 Uterine Neoplasms resveratrol 8.4717044934
MESH:D014605 Uveitis Dexamethasone 4.491336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2514671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 9.2817678736 16364871 17334414 17638931
MESH:D018487 Ventricular Dysfunction, Left resveratrol 9.2817488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9215886252
Pathway ID Pathway Name
KEGG:00520 Amino sugar and nucleotide sugar metabolism
KEGG:00524 Butirosin and neomycin biosynthesis
KEGG:04973 Carbohydrate digestion and absorption
KEGG:00051 Fructose and mannose metabolism
KEGG:00052 Galactose metabolism
KEGG:00010 Glycolysis / Gluconeogenesis
KEGG:04910 Insulin signaling pathway
KEGG:01100 Metabolic pathways
REACT:474 Metabolism of carbohydrates
KEGG:00500 Starch and sucrose metabolism
REACT:15518 Transmembrane transport of small molecules
KEGG:04930 Type II diabetes mellitus
Pharmacogenomics Knowledge Base Top
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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