AutismKB 2.0

Annotation Detail for ANXA13


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Basic Information Top
Gene Symbol:ANXA13 ( ANX13,ISA,MGC150460 )
Gene Full Name: annexin A13
Band: 8q24.13
Quick LinksEntrez ID:312; OMIM: 602573; Uniprot ID:ANX13_HUMAN; ENSEMBL ID: ENSG00000104537; HGNC ID: 536
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
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Desease Name
CHEMDEPENDENCY
smoking cessation
No data
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of ANXA13 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in increased expression of ANXA13 mRNAincreases expression 20406850
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of ANXA13 mRNAaffects expression 21346803
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ANXA13 mRNAaffects cotreatment|increases expression 17942748
D005492 Folic Acid Folic Acid affects the expression of ANXA13 mRNAaffects expression 17868486
C051890 irinotecan irinotecan analog results in decreased expression of ANXA13 mRNAdecreases expression 18927307
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ANXA13 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of ANXA13 mRNAincreases expression 17426115
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ANXA13 mRNAaffects cotreatment|increases expression 17942748
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.2411752688 14514962 15322242
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.3817505938
MESH:D058186 Acute Kidney Injury Folic Acid 4.6117003819 16316344 16595132
MESH:D055371 Acute Lung Injury pirinixic acid 3.4218653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8614692618
MESH:D000236 Adenoma Folic Acid 3.9416963246
MESH:D018248 Adenoma, Liver Cell pirinixic acid 11.2616434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 11.2616835633
MESH:D000544 Alzheimer Disease Folic Acid 3.0917116317
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.2111748828
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.8211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8215885639
MESH:D001321 Autistic Disorder Folic Acid 2.8121388746
MESH:D001778 Blood Coagulation Disorders pirinixic acid 9.7319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.7312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.2315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.9315746008
MESH:D001943 Breast Neoplasms Folic Acid 2.2916777985
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.2920435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.0216835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 3.0616705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 3.0616705839
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5018670907 16120746 18850075
MESH:D002318 Cardiovascular Diseases Folic Acid 4.1316755160
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 2.956135515
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.4116835633
MESH:D002779 Cholestasis Ethinyl Estradiol 8.4217333356 16919318 15861022 16105132 11677210 17681005 17110522
MESH:D002779 Cholestasis pirinixic acid 8.4219176532
MESH:D002971 Cleft Lip Folic Acid 4.1021254359
MESH:D002972 Cleft Palate Folic Acid 6.438946559 21254359
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 6.4312621046 8697196 15668235 15340226 16354765
MESH:D003110 Colonic Neoplasms irinotecan 2.6317725105 17287894
MESH:D015179 Colorectal Neoplasms Folic Acid 3.0417116713 17245555 16985020 16963246 17087956
MESH:D015179 Colorectal Neoplasms irinotecan 3.0415273666 16391804 17454858 16303861 17159606 18509181 18259882
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.3114669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2610048152 20055451 15322242
MESH:D003490 Cyanosis 2,4-dinitrotoluene 12.1218551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 12.1218551238
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5318249437
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 4.7516886840
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.7517107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 6.5718551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 6.5721346803 18551238
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.5720420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9611462148
MESH:D004487 Edema pirinixic acid 7.4812083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 7.4811000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.3518230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.5212538720
MESH:D016889 Endometrial Neoplasms Folic Acid 4.1817301261
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.2910568697 9294722
MESH:D017889 Exfoliation Syndrome Folic Acid 5.8916504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.2111564622
MESH:D005234 Fatty Liver Ethinyl Estradiol 8.5015345470
MESH:D005234 Fatty Liver pirinixic acid 8.5019236843 20131406
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.8111858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.3120067830
MESH:D005756 Gastritis Folic Acid 5.5317171786
MESH:D005901 Glaucoma Folic Acid 5.3816504073
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.0410696789
MESH:D006330 Heart Defects, Congenital Folic Acid 7.3016524890 17286298
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 7.3010048152 11294989
MESH:D006333 Heart Failure pirinixic acid 2.6920558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.6211000095
MESH:D006529 Hepatomegaly pirinixic acid 9.4816221962 19772884 19176532 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 9.4816120746 15340226 12621046
MESH:D006679 HIV Seropositivity Folic Acid 5.8917209195
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.4915340226 18606429 8697196 16959395 16354765
MESH:D006943 Hyperglycemia pirinixic acid 3.4520558911
MESH:D020138 Hyperhomocysteinemia Folic Acid 4.7416395265 16755160 16397167 16865747 16433478
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9918670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 4.1716569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.7712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.6617937319
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.9812878042 12200463
MESH:D007333 Insulin Resistance pirinixic acid 2.8016306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.6216580747
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 8.1516705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.1516705839
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.2015474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.2012878042
MESH:D008107 Liver Diseases Folic Acid 3.0916877991
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 7.857678174
MESH:D008113 Liver Neoplasms pirinixic acid 7.8516377806 20007298 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 7.8516984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 6.276135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 6.2712151625
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 1.2419555203 11884234
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.4017718048
MESH:D019767 Maxillofacial Abnormalities Folic Acid 6.0916832597
MESH:D052016 Mucositis irinotecan 5.4017159606
MESH:D009135 Muscular Diseases pirinixic acid 3.8616239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2419151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.2412213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1616411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 11.7018551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 11.7018551238 7678174
MESH:D009362 Neoplasm Metastasis irinotecan 3.2618259882
MESH:D009369 Neoplasms pirinixic acid 2.0617405874
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.5414600291
MESH:D009436 Neural Tube Defects Folic Acid 4.1217438019
MESH:D009447 Neuroblastoma irinotecan 3.608761367
MESH:D017599 Neuroectodermal Tumors irinotecan 5.128761367
MESH:D009503 Neutropenia Folic Acid 4.8116322990
MESH:D009765 Obesity pirinixic acid 1.8620558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 9.7816049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 9.7816049721
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.9911578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.6912520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.8918163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.5911222880 11118676 11399792 11896295
MESH:D011537 Pruritus Ethinyl Estradiol 3.7116919318 15861022
MESH:D051437 Renal Insufficiency Folic Acid 5.1415728788
MESH:D015427 Reperfusion Injury pirinixic acid 2.5019058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.1718990726
MESH:D012559 Schizophrenia Folic Acid 2.9216641680
MESH:D012640 Seizures 2,4-dinitrotoluene 6.4718551238
MESH:D012640 Seizures 2,6-dinitrotoluene 6.4718551238
MESH:D012871 Skin Diseases Folic Acid 3.3018709164
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.1516192470
MESH:D013088 Spermatocele Ethinyl Estradiol 4.3816709447
MESH:D013118 Spinal Cord Diseases Folic Acid 5.8916361298
MESH:D013274 Stomach Neoplasms Folic Acid 3.0317171786
MESH:D013274 Stomach Neoplasms irinotecan 3.0315723263
MESH:D020521 Stroke Folic Acid 4.5516517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.9211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.4015669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.3512697716
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.3216049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.3216049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 13.3510091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 13.3510091137
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.6314692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.0412125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.8214671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.6915886252
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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