AutismKB 2.0

Annotation Detail for MR1


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Basic Information Top
Gene Symbol:MR1 ( FLJ31593,HLALS )
Gene Full Name: major histocompatibility complex, class I-related
Band: 1q25.3
Quick LinksEntrez ID:3140; OMIM: 600764; Uniprot ID:HMR1_HUMAN; ENSEMBL ID: ENSG00000153029; HGNC ID: 4975
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
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Desease Name
Paroxysmal nonkinesigenic dyskinesia
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of MR1 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MR1 mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of MR1 mRNAincreases expression 20106945
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of MR1 mRNAaffects expression 17484886
D016572 Cyclosporine Cyclosporine results in decreased expression of MR1 mRNAdecreases expression 20106945
D004041 Dietary Fats Dietary Fats results in increased expression of MR1 mRNAincreases expression 18042831
D005472 Fluorouracil Fluorouracil results in increased expression of MR1 mRNAincreases expression 16101138
D009151 Mustard Gas Mustard Gas results in increased expression of MR1 mRNAincreases expression 15674844
D010126 Ozone Ozone results in decreased expression of MR1 mRNAdecreases expression 12763052
C041786 palm oil palm oil results in increased expression of MR1 mRNAincreases expression 18042831
D010634 Phenobarbital Phenobarbital results in increased expression of MR1 mRNAincreases expression 19270015
D020849 Raloxifene Raloxifene results in increased expression of MR1 mRNAincreases expression 19429434
D013629 Tamoxifen Tamoxifen results in increased expression of MR1 mRNAincreases expression 19429434
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of MR1 mRNAincreases expression 20106945
D014810 Vitamin E Vitamin E results in decreased expression of MR1 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6114745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 8.466195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.4615322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.6118287403
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.4220127859 20464547
MESH:D000230 Adenocarcinoma Fluorouracil 4.4217638652
MESH:D000236 Adenoma Benzo(a)pyrene 2.676695378
MESH:D018248 Adenoma, Liver Cell Phenobarbital 10.2517620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.2516835633
MESH:D000419 Albuminuria Raloxifene 4.6317308373 17451421
MESH:D000544 Alzheimer Disease Ozone 4.3915513908
MESH:D000544 Alzheimer Disease Raloxifene 4.3915800139
MESH:D000740 Anemia Fluorouracil 8.7717963324 15504547 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.7711748828
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.1219183758
MESH:D001161 Arteriosclerosis Dietary Fats 3.9315238619
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5615570426
MESH:D001249 Asthma Mustard Gas 5.1110378619
MESH:D001249 Asthma Ozone 5.1117854713 16373670
MESH:D001768 Blister Mustard Gas 5.2119167455
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.0712125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7815746008
MESH:D001930 Brain Injuries Raloxifene 4.5216580743
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.9720146248 17474063
MESH:D001943 Breast Neoplasms Dietary Fats 2.9720435547
MESH:D001943 Breast Neoplasms Fluorouracil 2.9719217205 16557594 15136595 18357371 18608205 16595493 16110121
MESH:D001943 Breast Neoplasms Raloxifene 2.9716912660 17242785 15758505 17595753 17261762 17049068 17952589 15775269 15572757 17440819 17893378 16837676
MESH:D001943 Breast Neoplasms Tamoxifen 2.9721152245 20135344 21138602 19189210 16873071 16818667 16273361 20005174 19410462 18425577 19189212 20544844 19103187 18351453 20859285 18984771 19244106 17893378 19288272 19115204 17242785 16202921 19059307 19155303 17261762 11161223 20390343 18815881 17440819 15668708 19487384 19011961 17049068 19289846 19200415 15565566 19084267 18629630 20065188 18855134 18997820 19142967 18821012 19221464 19066611
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.9720435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.7015516495 14754758 18315731 19059883 18417511 17626835 16777450
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 5.2115286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 5.0417687719 10378619
MESH:D002100 Cachexia Ozone 4.7916183385
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 10.0816227642 15721981 15700767 16050911 16124888 18705752 15673190 16192424 16011737 3786805 10355542 16097048
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 10.0816050911
MESH:D002276 Carcinoid Tumor Fluorouracil 4.7316051944
MESH:D002277 Carcinoma Fluorouracil 8.2617121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.2616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5519066611
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 8.9321507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 8.9318788625
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 8.9317971768 16332177 16799960 17045692 18930000 17088986
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 8.9317173139 6705139 20935162 1701930 20007298
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 8.9316924424
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 3.0318695887
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.6720419170
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 4.6716757204 17066447 16280240 18986760
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 9.5917572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 9.5917572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3818850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases Raloxifene 3.4615775269
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.5412371664
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.294080065
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1916835633
MESH:D002779 Cholestasis Cyclosporine 2.9419486331
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1115340226 8697196 12621046 16354765 15668235
MESH:D003072 Cognition Disorders Raloxifene 4.6615800139
MESH:D003110 Colonic Neoplasms Fluorouracil 2.2418772588 17287894 15001691 17172411 17725105 16340194 16510598 17016597 17169374 17018589
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.0014970324 20501625 18288408 16524972 18949393 18448328 17255274 15148649 18383874 16391804 16303861 18802399 17454858 16282729 17594712 17695437 17016601 16331619 15289873 17094418 18509181 17401013
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0814669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4910048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.4919769572
MESH:D007644 Darier Disease Fluorouracil 4.8416733453
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4019031437
MESH:D003865 Depressive Disorder, Major Raloxifene 4.1917474826
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6717107852
MESH:D003928 Diabetic Nephropathies Raloxifene 9.1217308373 15920148 17451421
MESH:D003928 Diabetic Nephropathies Tamoxifen 9.1219279558
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 3.7510092053 17522070 6623471 10915739 7179309 2869522 6884620 4309450 16227642 16177239 15998439 19085960 9327722 15968718 3786805 21278145 19336974 7440962 3732212 15027814 7120509 11566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.7520420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7811462148
MESH:D050171 Dyslipidemias Dietary Fats 3.4718367378
MESH:D004421 Dystonia Phenobarbital 4.041851702
MESH:C538011 Eales disease Vitamin E 4.779068938
MESH:D004487 Edema Mustard Gas 11.719260866 11402378 11428631 11428647
MESH:D004487 Edema Raloxifene 11.7115860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.7112711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9618230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 9.3615845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 9.3619031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.0620544844 19155303 17893378 16202921
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.059294722 10568697
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.153659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.933922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.9020417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.576401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.297750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.073659116
MESH:D004890 Erythema Mustard Gas 5.219357497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.5116530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 4.5116785472 16481741 15173087 17638652 16337965
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0311564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 25.0012795759 16239168 15959796 19224547 12631006 61145 16045604 17595544
MESH:D005234 Fatty Liver Cyclosporine 25.0019224547
MESH:D005234 Fatty Liver Dietary Fats 25.0019551842 18296743 19004024 17967931
MESH:D005234 Fatty Liver Raloxifene 25.0017473493
MESH:D005234 Fatty Liver Tamoxifen 25.0014986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2516709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5011858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.5814745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.2319069698
MESH:D005355 Fibrosis Carbon Tetrachloride 21.5218705752
MESH:D005355 Fibrosis Cyclosporine 21.5212639820 12168785
MESH:D005355 Fibrosis Dietary Fats 21.5218296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 21.5220067830
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.278708960
MESH:D005910 Glioma Fluorouracil 2.8816145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6610696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.4015102660 18337622 15162350
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 11.1920471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.1911294989 10048152
MESH:D006330 Heart Defects, Congenital Vitamin E 11.1916080930
MESH:D006331 Heart Diseases Raloxifene 3.5511110106
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.4715720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3611000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.6319110552 19900420
MESH:D006529 Hepatomegaly Phenobarbital 8.5816109766
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.5812621046 16120746 15340226
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7116490937 16863852
MESH:D019584 Hot Flashes Vitamin E 4.0314716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1118606429 8697196 16354765 15340226 16959395
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.5816899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.6221332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.6521332399
MESH:D006973 Hypertension Cyclosporine 8.6410903974
MESH:D006973 Hypertension Raloxifene 8.6415787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.6418850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.1315338365
MESH:D007249 Inflammation Dietary Fats 12.0920412841
MESH:D007249 Inflammation Mustard Gas 12.0911428620 11428631 8975870 11402378 17524151 11428647 9260866 9357497 16001271
MESH:D007249 Inflammation Tamoxifen 12.0919457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 12.0912200463 12878042
MESH:D007251 Influenza, Human Vitamin E 4.2816624496
MESH:D007333 Insulin Resistance Dietary Fats 3.1211836018 18457598
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3616580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.5015604871
MESH:D007674 Kidney Diseases Cyclosporine 6.0718776723 10903974 8314463
MESH:D007674 Kidney Diseases Vitamin E 6.0712488133
MESH:D007680 Kidney Neoplasms Cyclosporine 12.5612371664
MESH:D007680 Kidney Neoplasms Fluorouracil 12.5616985049
MESH:D007680 Kidney Neoplasms Tamoxifen 12.5618625569
MESH:D007889 Leiomyoma Raloxifene 4.5316973256
MESH:D008064 Lipidoses Tamoxifen 3.1717567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 11.1216943688 16239168 17157831 17334410 17174718 16221502 11408273 11903743 21278145
MESH:D008103 Liver Cirrhosis Dietary Fats 11.1218296743
MESH:D008103 Liver Cirrhosis Phenobarbital 11.1221047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.9717557913 17565644 16638106 18418968 18251166 12741479 18187930 11481614 16248980 17525996 17805973 14512876 12632512 17944888 17714472 12609069 17708605 12389079 16015684 18205269 15338365 15052691 18412020 18279442 17761835 15650968 18395914 18054572 16192424 10355542 12666154 12667390 18210741 12958196 15931870 17976157 18277467 17698563 15362042 18006644 15818738 15370692 15673190 12445421 14748882 12586293 15730626 15123356 18472332 18420326 17823541 15057751 14716496 16027843 12546737 14716833 17631135 15925388 18339082 15876570 18376398 15893842 12898905 17766677 12632514 18429990 16136751 16116963 18472094 17721639 17922224 12649538 17869086 18156304 17481882 20821823 15959796 18481824 18705752 18263696 18317297 17900296 14724832 16011737 12445418 18395095 16033810 14620537 17640975 13678700 15996030 16097048 18166357
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.9718564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.9712878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.9716169303
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.1215830285 16246199 17285989 15720792 16964402
MESH:D008107 Liver Diseases Phenobarbital 4.1219363144
MESH:D017093 Liver Failure Carbon Tetrachloride 4.2115123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.7216899240 14706259
MESH:D008113 Liver Neoplasms Aflatoxin B1 22.092125692 18177683 9163691 15890375
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 22.0920195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 22.0919294768
MESH:D008113 Liver Neoplasms Fluorouracil 22.0915113037 17045692 18383874 16603448
MESH:D008113 Liver Neoplasms Phenobarbital 22.0919812893 21047994 15975961 19482888 8742319 19073162
MESH:D008113 Liver Neoplasms Tamoxifen 22.0916684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 22.0916984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 14.268603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 14.2615583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 14.2618308698 6150874 1399818 17172636 2563599
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 14.2612151625
MESH:D008171 Lung Diseases Mustard Gas 12.5218702808 18161513
MESH:D008171 Lung Diseases Ozone 12.5219066396 8266340
MESH:D008171 Lung Diseases Vitamin E 12.5216863852
MESH:D055370 Lung Injury Ozone 3.8920417186
MESH:D008175 Lung Neoplasms Aflatoxin B1 13.0914755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 13.0918569708 6695378 20464547 20064080 18816296 17053015 20869020 18520028 20135361
MESH:D008175 Lung Neoplasms Fluorouracil 13.0915246190
MESH:D008175 Lung Neoplasms Mustard Gas 13.098781369 3148597
MESH:D008175 Lung Neoplasms Ozone 13.098597069 7614698
MESH:D008175 Lung Neoplasms Tamoxifen 13.0918625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 13.0911884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 13.0911062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.8415086387
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.8119428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.6416827153 19196722 11731420 14580682 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 4.6119453300
MESH:D008545 Melanoma Tamoxifen 1.8819393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.2315990972
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.8516801185
MESH:D008679 Metaplasia Ozone 5.1710496685
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.6215863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.6016381670
MESH:D009062 Mouth Neoplasms Fluorouracil 8.6018986760 16757204
MESH:D009101 Multiple Myeloma Raloxifene 3.4616497877
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0412213967
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.5317484760
MESH:D009232 Myxoma Raloxifene 5.6216343187
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.5519393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5219410462
MESH:D009369 Neoplasms Benzo(a)pyrene 5.1111141357
MESH:D009369 Neoplasms Fluorouracil 5.1118600527 18239605 16928823
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.0619196722 19189210 19200415
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.5017954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.3119348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.2514600291
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.4516436463
MESH:D009503 Neutropenia Mustard Gas 4.0016761898 7688884
MESH:D009765 Obesity Dietary Fats 2.2917217161 16723640 20518802 20132043 21332399 18674790 11836018 19632207 18457598
MESH:D010018 Osteomalacia Phenobarbital 4.4117016548
MESH:D010024 Osteoporosis Raloxifene 3.4117882678 15775268 19059307
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.2617823083 15758505 17893378 15579764
MESH:D010190 Pancreatic Neoplasms Fluorouracil 5.3816500647 16929163 15113037 19003803
MESH:D010190 Pancreatic Neoplasms Phenobarbital 5.3816965848
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3112520081
MESH:D010538 Peritonitis Ozone 4.1716369182
MESH:D011014 Pneumonia Ozone 4.4418007984 18929643 18381685
MESH:D011041 Poisoning Mustard Gas 3.8315727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5918163543
MESH:D011230 Precancerous Conditions Cyclosporine 9.0512371664
MESH:D011230 Precancerous Conditions Phenobarbital 9.052563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2411222880 11118676 11896295 11399792
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.8617292933
MESH:D011471 Prostatic Neoplasms Fluorouracil 1.8618626508 19082440
MESH:D011471 Prostatic Neoplasms Raloxifene 1.8615731164 16220300 16536755
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8615067354
MESH:D011471 Prostatic Neoplasms Vitamin E 1.8615084515
MESH:D011537 Pruritus Mustard Gas 4.1418058305
MESH:D019310 Pseudolymphoma Phenobarbital 4.5612752131
MESH:D011565 Psoriasis Cyclosporine 2.2416882103
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.9417266442 10334151 17894541 17620002 17720292
MESH:D011693 Purpura Raloxifene 5.6215770314
MESH:D012004 Rectal Neoplasms Fluorouracil 4.0418722050 16160472 15538739 18286688
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8718990726
MESH:D012640 Seizures Phenobarbital 2.7111442880 3137016 4039156 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.876407741
MESH:D012871 Skin Diseases Mustard Gas 5.0512880345 15451306 16961503
MESH:D012871 Skin Diseases Vitamin E 5.0518709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.5119755658 10029692
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.5116192470
MESH:D013088 Spermatocele Tamoxifen 4.3516709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0919457130
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.4320155912 2093021
MESH:D013274 Stomach Neoplasms Fluorouracil 2.4318396642 17522103 16424979 15786421 19015929 18567086 19084572 17172411 17498489 16951190
MESH:D020521 Stroke Raloxifene 8.7816837676
MESH:D020521 Stroke Vitamin E 8.7816517955
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9612697716
MESH:D013964 Thyroid Neoplasms Phenobarbital 3.071399818
MESH:D013978 Tibial Fractures Raloxifene 5.2719048282
MESH:D014062 Tongue Neoplasms Fluorouracil 4.0216280240
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.4117053015
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 8.4117572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.4116712894 8653321 17572228
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.9016803524
MESH:D014605 Uveitis Cyclosporine 4.051336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6612125929
MESH:D054556 Venous Thromboembolism Raloxifene 5.2716837676
MESH:D014846 Vulvar Neoplasms Raloxifene 5.6216343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3115886252
MESH:D015430 Weight Gain Dietary Fats 3.7616723640
MESH:D014985 Xerophthalmia Cyclosporine 4.5017120751
Pathway ID Pathway Name
KEGG:04514 Cell adhesion molecules (CAMs)
KEGG:04144 Endocytosis
KEGG:04145 Phagosome
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB00098 antagonist Antithymocyte globulin Immunomodulatory Agents
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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