AutismKB 2.0

Annotation Detail for HMGN2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:HMGN2 ( HMG17,MGC5629,MGC88718 )
Gene Full Name: high-mobility group nucleosomal binding domain 2
Band: 1p36.11
Quick LinksEntrez ID:3151; OMIM: 163910; Uniprot ID:HMGN2_HUMAN; ENSEMBL ID: ENSG00000198830; HGNC ID: 4986
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C063002 2,3-dimethoxy-1,4-naphthoquinone 2,3-dimethoxy-1,4-naphthoquinone results in increased expression of HMGN2 mRNAincreases expression 17547211
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of HMGN2 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of HMGN2 mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of HMGN2 mRNAincreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of HMGN2 mRNAaffects expression 17562736
C006632 arsenic trioxide arsenic trioxide results in increased expression of HMGN2 mRNAincreases expression 20458559
17547211
C006780 bisphenol A bisphenol A results in decreased expression of HMGN2 mRNAdecreases expression 19371625
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of HMGN2 mRNAaffects expression 17484886
D002330 Carmustine Carmustine results in decreased expression of HMGN2 mRNAdecreases expression 15980968
D002857 Chromium Chromium results in increased expression of HMGN2 mRNAincreases expression 17547211
D003345 Corticosterone Corticosterone results in decreased expression of HMGN2 mRNAdecreases expression 15755911
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of HMGN2 mRNAincreases expression 17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of HMGN2 mRNA]decreases reaction|increases expression 17854601
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of HMGN2 mRNAdecreases expression 17557909
D015025 Zearalenone Zearalenone results in decreased expression of HMGN2 mRNAdecreases expression 19371625
D019833 Genistein Genistein results in decreased expression of HMGN2 mRNAdecreases expression 18847459
19371625
D017313 Fenretinide Fenretinide results in decreased expression of HMGN2 mRNAdecreases expression 16671099
D008628 Mercury Mercury results in increased expression of HMGN2 mRNAincreases expression 17547211
C016340 o,p'-DDT o,p'-DDT results in decreased expression of HMGN2 mRNAdecreases expression 19371625
D011192 Potassium Dichromate Potassium Dichromate results in increased expression of HMGN2 mRNAincreases expression 17547211
C059514 resveratrol resveratrol results in decreased expression of HMGN2 mRNAdecreases expression 19371625
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8617505938
MESH:D058186 Acute Kidney Injury resveratrol 3.7716538975
MESH:D000230 Adenocarcinoma arsenic trioxide 10.0411798837 19825857
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.0414692618
MESH:D000230 Adenocarcinoma Fenretinide 10.0410697514
MESH:D000230 Adenocarcinoma Genistein 10.0411473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 10.923712494
MESH:D000236 Adenoma Diethylnitrosamine 10.926695378 10737359
MESH:D000236 Adenoma resveratrol 10.9215688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 3.8219052882 17162532 19061943 18056438 17620307 16434500
MESH:D000544 Alzheimer Disease resveratrol 2.5516162502 16183991
MESH:D000799 Angioedema Acetaminophen 3.7610982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.3811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.1815885639
MESH:D001169 Arthritis, Experimental resveratrol 7.1817115116
MESH:D050197 Atherosclerosis resveratrol 3.2217967414 16873680
MESH:D001321 Autistic Disorder Acetaminophen 2.1418445737
MESH:D001321 Autistic Disorder Mercury 2.1417497416
MESH:D001327 Autoimmune Diseases Mercury 4.7816634805
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.9411289319 1440618
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 3.5916206674
MESH:D001862 Bone Resorption bisphenol A 3.7811985600
MESH:D002545 Brain Ischemia resveratrol 4.2017600658
MESH:D001932 Brain Neoplasms Carmustine 9.0616187019
MESH:D001932 Brain Neoplasms Fenretinide 9.0616187019
MESH:D001943 Breast Neoplasms bisphenol A 2.9417123778
MESH:D001943 Breast Neoplasms Chromium 2.9415986119
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.9417474063
MESH:D001943 Breast Neoplasms Fenretinide 2.9416601279
MESH:D001943 Breast Neoplasms Genistein 2.9416873071 17200150 16541309
MESH:D001943 Breast Neoplasms resveratrol 2.9417651959 16393696 17534123
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.2411589617
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.6915700767 10355542 16227642 3786805 16192424 16124888 15721981 16050911 15673190 16011737 18705752 16097048
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 22.7516705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 22.7516705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 22.757296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 22.753084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 22.7515073043 14691202 15553829 16217749 11135700
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 22.7518788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 22.7518978308 18506893 19335982 17978847 16698587 18788625 20101231 16328049 11831363 20514400 18665156 16502159 16681979 17173139 19822196 17138121 17428255 18393292 20524982 16878318 18785209 17761372 10737359 16288022 16807293 19919837 20935162 19208518 17162532 19171122 18494052 20214788 20432363 16935385 20007298 17055752 16830150 16569478 19418558 10672840 18971187 20727157 19519916 19539802 20512989 19052882 19383236 19701751 18691550 3084413 16779866 18210153 20084675 21159647 16540662 19107877 3581430 18056438 19394651
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 22.7516270382 17159502
MESH:D006528 Carcinoma, Hepatocellular Genistein 22.7516924424
MESH:D006528 Carcinoma, Hepatocellular resveratrol 22.7519321006 16227395
MESH:D002278 Carcinoma in Situ bisphenol A 4.9017123778
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.5116675471
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7919014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.637296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.0412490120
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 5.0516274795
MESH:D002294 Carcinoma, Squamous Cell resveratrol 5.0516227395
MESH:D002311 Cardiomyopathy, Dilated Mercury 3.4210334427
MESH:D002318 Cardiovascular Diseases Genistein 7.3116332659
MESH:D002318 Cardiovascular Diseases resveratrol 7.3115458977
MESH:D002386 Cataract Acetaminophen 2.5310977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 10.836135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 10.837505956
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 10.837505956 17174075 2727394 21159647
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 5.3916154183
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.6119052882
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 7.6419486331 9022650
MESH:D002779 Cholestasis Ethinyl Estradiol 7.6415861022 16919318 11677210 17681005 17333356 16105132 17110522
MESH:D003092 Colitis resveratrol 4.0416474422
MESH:D003110 Colonic Neoplasms Genistein 3.8817182828
MESH:D003110 Colonic Neoplasms resveratrol 3.8816338953
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.5420501625
MESH:D015179 Colorectal Neoplasms Fenretinide 3.5417273769
MESH:D015179 Colorectal Neoplasms resveratrol 3.5416550006
MESH:D003327 Coronary Disease resveratrol 3.6916507316
MESH:D023903 Coronary Restenosis arsenic trioxide 4.1012609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8810525206
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.6018551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.6018551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.0115213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 11.3212868966 2524372 8156756 11298694 18759878 8970840 14531868 11906362
MESH:D017449 Dermatitis, Allergic Contact Mercury 11.3216823706
MESH:D017449 Dermatitis, Allergic Contact Potassium Dichromate 11.3216823706
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.412952479 3621924
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.6916873680
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.4520387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 4.4516647724
MESH:D003928 Diabetic Nephropathies resveratrol 3.8916286809
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 14.9221346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 14.9221346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 14.9218692083 18648102 18289764 9328219 16192314 6679447 7440962 8291058 11289319 9022650 9653073 1440618 6482804
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 14.922444490 18071297 19923254 11421492 17562736 16227642 19164858 12958197 12594235 17906064 10663392 16177239 18713872 12705907 15619225 16081117 16485898 10915739 11529661 14725611 12392966 19085960 19420014 11834606 16393943 19416960 11739529 11461765 12153990 19739265 11743745 11287661 10774834 16109766 12540782 15968718 14550746 14986274 19370779 16781746 17522070
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 14.9215027814 21278145 3732212 19085960 15998439 7440962 19336974 16177239 10092053 15968718 3786805 16227642 11566570 2869522 7120509 17522070 6623471 4309450 6884620 9327722 7179309 10915739
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 14.9219107877
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0219426721
MESH:D004487 Edema resveratrol 3.298985016
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.8412538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 8.8417872969
MESH:D004714 Endometrial Hyperplasia Genistein 4.5016402032
MESH:D016889 Endometrial Neoplasms Genistein 3.3011473722
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.7617923197
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0416302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.403581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.4012903497
MESH:D005234 Fatty Liver arsenic trioxide 18.1015073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 18.1012631006 19224547 15959796 16045604 12795759 16239168 61145 17595544
MESH:D005234 Fatty Liver Diethylnitrosamine 18.1021071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 18.1015345470
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.946705139
MESH:D005355 Fibrosis Carbon Tetrachloride 3.3718705752
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1816904648
MESH:D005756 Gastritis Acetaminophen 3.5916983495
MESH:D005909 Glioblastoma Carmustine 11.7916187019
MESH:D005909 Glioblastoma Fenretinide 11.7916187019
MESH:D005909 Glioblastoma Genistein 11.7916598420
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.957505956
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.946705139
MESH:D006505 Hepatitis Carbon Tetrachloride 8.9419900420 19110552
MESH:D006561 Herpes Simplex resveratrol 4.0916876885
MESH:D006930 Hyperalgesia Acetaminophen 2.6316870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.4516899240
MESH:D006937 Hypercholesterolemia resveratrol 3.9217188708
MESH:D006949 Hyperlipidemias resveratrol 3.9416873680
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.8515034207
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.0015338365
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.2217488730
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7216945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.5617600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4317937319
MESH:D007249 Inflammation Diethylnitrosamine 5.1118785209
MESH:D007249 Inflammation resveratrol 5.1116366677
MESH:D007251 Influenza, Human resveratrol 4.4616624496
MESH:D007333 Insulin Resistance bisphenol A 3.2316393666
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.949022650 8074119
MESH:D007674 Kidney Diseases Acetaminophen 14.1912587719 15629191
MESH:D007674 Kidney Diseases Chromium 14.1917934191
MESH:D007674 Kidney Diseases Mercury 14.1917934191
MESH:D007674 Kidney Diseases Potassium Dichromate 14.1919665454
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 11.9716705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 11.9716705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 11.976582329
MESH:D007938 Leukemia arsenic trioxide 6.2915070760
MESH:D007938 Leukemia Genistein 6.2918980019 17468513
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.7117077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.2216972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.6819077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1216467208 20471514 19850784 17050201 16968895
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.6016331271 15622746 15748426 11161223 17217047 15336539 12018890 19225113 19075265 16966277 17107899 12679006 17649720 17869043 9834237 16330433 15213294 17712046 19642359 19035177 16112521 12712474 16891316 11468182 16823087
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 7.6016087638
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2716882451
MESH:D007972 Leukoplakia, Oral Fenretinide 5.9616707609
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.4511408273 11903743 16943688 17174718 16239168 21278145 16221502 17157831 17334410
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.4518665156 19638242 18522880 18407596 20032147
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.149327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 2.5618277467 17640975 18472332 18395095 14748882 16097048 16015684 15057751 17922224 14716833 12546737 16192424 16638106 20821823 17869086 18156304 17698563 17944888 18395914 18412020 16136751 15650968 12389079 11481614 17761835 13678700 15818738 12445421 15673190 15893842 17708605 15123356 16248980 16116963 18472094 17525996 14512876 16033810 15370692 18420326 17557913 17805973 12666154 18705752 17823541 17721639 17481882 12609069 12445418 18418968 15730626 18279442 14716496 18317297 15931870 16027843 12649538 15338365 18054572 18481824 17714472 15996030 18376398 18263696 18251166 18205269 12898905 14724832 18210741 15959796 12632514 15052691 18006644 10355542 14620537 15876570 15925388 17631135 18166357 17900296 18429990 12667390 12958196 12741479 15362042 17565644 12632512 18187930 16011737 17766677 17976157 12586293 18339082
MESH:D008106 Liver Cirrhosis, Experimental Genistein 2.5617823541
MESH:D008107 Liver Diseases Acetaminophen 6.3419460945 16610002 19784758 12587719 19014921 16611625 11587558 12969438
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.3416246199 15720792 16964402 15830285 17285989
MESH:D008107 Liver Diseases Diethylnitrosamine 6.3417034775
MESH:D017093 Liver Failure Carbon Tetrachloride 4.0815123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.1416871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.1414706259 16899240
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 13.907678174
MESH:D008113 Liver Neoplasms arsenic trioxide 13.9014682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 13.9019294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 13.9019850985 12112319 20492335 20101389 21047994 20137499 21071580 21278145 19833225 20452335 19090486 12771043 20434301 18648771 20118626 15175105 20583210 19254457 19642983 19812893 16942905 19638242 15885732 19294768 9163691 19499222 2862719 18977376 2422723 18754104 18978307 18644402 19551842 19690152 20405173 19426721 10737359 19427195 19996281 21167192 19256749 20501860 19255062 19073162
MESH:D008113 Liver Neoplasms resveratrol 13.9019812893 19073162 19321006 20405173
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 18.062876786 2876784 6135515
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 18.06598648 6587162 3712494 1399818
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 18.0620377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 18.0612014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 18.0617942915 18775883 3124819 18079962 18253720 19539802 21159647 18544905 17854601 16267830 18164116 19009564 2563599 17174075 9362446 18282651 19004024 18093689 16842330 19126423 18308698 19519916
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2815213294
MESH:D008175 Lung Neoplasms arsenic trioxide 2.4611798837 19825857
MESH:D008175 Lung Neoplasms Diethylnitrosamine 2.4621163286 20970405 20512841 6695378
MESH:D016393 Lymphoma, B-Cell resveratrol 4.2117088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.8014749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.1615688416
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 13.9212807724
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 13.9210697514
MESH:D008325 Mammary Neoplasms, Experimental Genistein 13.9214578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 13.9211606380 8985016
MESH:D008545 Melanoma Carmustine 5.3012393984
MESH:D008545 Melanoma Fenretinide 5.3016270382
MESH:D008545 Melanoma resveratrol 5.3017992120
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4819513568
MESH:D008659 Metabolic Diseases resveratrol 4.2917112576
MESH:D009062 Mouth Neoplasms Fenretinide 4.2516274795
MESH:D009101 Multiple Myeloma arsenic trioxide 7.2111468182 19417148 14977855 19549372 15949261
MESH:D009101 Multiple Myeloma resveratrol 7.2117049120 16267019 16490592 17935668 17164350 14749477
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.7817962980
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5918349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.0916882451 16105982
MESH:D009203 Myocardial Infarction Genistein 5.8817141266
MESH:D009203 Myocardial Infarction resveratrol 5.8817015251 17188708 16317513 16525036 16456233 17125593
MESH:D017202 Myocardial Ischemia resveratrol 3.9417125593 17015251
MESH:D015428 Myocardial Reperfusion Injury Genistein 3.5917141266
MESH:D009205 Myocarditis resveratrol 4.6717322642
MESH:D009336 Necrosis 2,4-dinitrotoluene 10.0618551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 10.067678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.8716624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.593581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.593581430 9029167
MESH:D009369 Neoplasms Fenretinide 3.2517353921 15958647
MESH:D009374 Neoplasms, Experimental resveratrol 3.918985016
MESH:D009421 Nervous System Malformations bisphenol A 9.6016427766 11399458
MESH:D009421 Nervous System Malformations Genistein 9.6016427766
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.066679447
MESH:D009436 Neural Tube Defects arsenic trioxide 7.0610525206
MESH:D019636 Neurodegenerative Diseases Acetaminophen 13.6318514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 13.6320387270
MESH:D019636 Neurodegenerative Diseases resveratrol 13.6317652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.3117929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0420387270
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 5.5916303764
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 14.6112819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 14.6116049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 14.616482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.943988306
MESH:D010024 Osteoporosis Genistein 3.2019401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 9.8716169203
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 9.8717513867
MESH:D010049 Ovarian Diseases bisphenol A 4.9011985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 7.8819769630 12452020 16624393
MESH:D010051 Ovarian Neoplasms Fenretinide 7.8816133793
MESH:D010051 Ovarian Neoplasms Genistein 7.8819005980
MESH:D010146 Pain Acetaminophen 2.3216870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.5515580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.5516540662
MESH:D010190 Pancreatic Neoplasms Fenretinide 8.5515580305
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6011578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.407296757
MESH:D010235 Paraganglioma arsenic trioxide 4.0819927285
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.396228378
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.472563599
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 9.5910548101
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 9.5916679765
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.1220887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8919131511
MESH:D011471 Prostatic Neoplasms bisphenol A 1.8916740699
MESH:D011471 Prostatic Neoplasms Fenretinide 1.8917024972
MESH:D011471 Prostatic Neoplasms Genistein 1.8916925846 15256057 15378649
MESH:D011471 Prostatic Neoplasms resveratrol 1.8917675339 15767336 17636462 17718901 17804756 16731767
MESH:D011537 Pruritus Ethinyl Estradiol 3.2316919318 15861022
MESH:D011629 Puberty, Precocious bisphenol A 4.7010548101
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.5016325855
MESH:D015427 Reperfusion Injury resveratrol 3.2316314181 17058453 15827377 16317513 17520802
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 8.893692021
MESH:D012162 Retinal Degeneration Fenretinide 8.8916303925
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.8716646077
MESH:D012640 Seizures 2,4-dinitrotoluene 5.6718551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.6718551238
MESH:D012878 Skin Neoplasms Fenretinide 6.1116467112
MESH:D012878 Skin Neoplasms resveratrol 6.118985016 15837718
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8616709447
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.4217007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.4218456281
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.4016321402
MESH:D019966 Substance-Related Disorders bisphenol A 3.9016684133 16045194
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0715669648
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 11.566582329 1399818 7505956 6587162 3712494
MESH:D013964 Thyroid Neoplasms arsenic trioxide 11.5619014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 11.567505956
MESH:D014062 Tongue Neoplasms resveratrol 4.1316227395
MESH:D016171 Torsades de Pointes arsenic trioxide 3.8815213294
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 15.4516049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 15.4516049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 15.458074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 15.4512845720 12973940 11780464 20435036
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 15.4516720286
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.7010091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.7010091137
MESH:D014581 Urticaria Acetaminophen 2.8910982225
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 9.5916154183
MESH:D002583 Uterine Cervical Neoplasms resveratrol 9.5917473185
MESH:D014591 Uterine Diseases bisphenol A 4.9314652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.2114692618
MESH:D014594 Uterine Neoplasms resveratrol 9.2117044934
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4614671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.2117488730
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved