AutismKB 2.0

Annotation Detail for HMMR


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Basic Information Top
Gene Symbol:HMMR ( CD168,IHABP,MGC119494,MGC119495,RHAMM )
Gene Full Name: hyaluronan-mediated motility receptor (RHAMM)
Band: 5q34
Quick LinksEntrez ID:3161; OMIM: 600936; Uniprot ID:HMMR_HUMAN; ENSEMBL ID: ENSG00000072571; HGNC ID: 5012
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04512ECM-receptor interaction
No data
No data
No data
No data
Related Diseases/Disorders Top
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Desease Name
Breast cancer, susceptibility to
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C010914 2,4-diaminotoluene 2,4-diaminotoluene results in increased expression of HMMR mRNAincreases expression 20713471
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in increased expression of HMMR mRNAincreases expression 20406850
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of HMMR mRNAincreases expression 18648102
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of HMMR proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of HMMR mRNAaffects expression 16483693
D001241 Aspirin Aspirin results in increased expression of HMMR mRNAincreases expression 11906190
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of HMMR mRNAdecreases expression 20064835
20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of HMMR mRNAdecreases expression 20018196
20382639
C002791 bismuth tripotassium dicitrate bismuth tripotassium dicitrate results in decreased expression of HMMR mRNAdecreases expression 15912405
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of HMMR mRNAaffects expression 17484886
D016572 Cyclosporine Cyclosporine results in decreased expression of HMMR mRNAdecreases expression 20106945
D004317 Doxorubicin HMMR protein affects the susceptibility to Doxorubicinaffects response to substance 16217747
D005419 Flavonoids Flavonoids results in decreased expression of HMMR mRNAdecreases expression 18035473
D005472 Fluorouracil TP53 protein affects the reaction [Fluorouracil results in decreased expression of HMMR mRNA]affects reaction|decreases expression 15016801
D006820 Hyaluronic Acid Hyaluronic Acid binds to and results in increased activity of HMMR proteinaffects binding|increases activity 16864594
C051890 irinotecan irinotecan metabolite results in decreased expression of HMMR mRNAdecreases expression 15956246
C051890 irinotecan irinotecan results in decreased expression of HMMR mRNAdecreases expression 15956246
C011890 kojic acid kojic acid results in decreased expression of HMMR mRNAdecreases expression 16595896
C533894 LG 100815 LG 100815 results in decreased expression of HMMR mRNAdecreases expression 16951191
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of HMMR mRNAincreases expression 20713471
C062198 octa-2,4,6-trienoic acid octa-2,4,6-trienoic acid results in decreased expression of HMMR mRNAdecreases expression 16951191
D010634 Phenobarbital Phenobarbital results in increased expression of HMMR mRNAincreases expression 19363144
C006253 pirinixic acid pirinixic acid results in increased expression of HMMR mRNAincreases expression 18301758
D011374 Progesterone Progesterone results in increased expression of HMMR mRNAincreases expression 18070364
D013467 Sulindac Sulindac results in decreased expression of HMMR mRNAdecreases expression 11906190
D014747 Vinblastine HMMR protein affects the susceptibility to Vinblastineaffects response to substance 16217747
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Sulindac 5.3014745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 3.256195326
MESH:D000138 Acidosis Ammonium Chloride 3.3718287403
MESH:D058186 Acute Kidney Injury Sulindac 4.147897758
MESH:D055371 Acute Lung Injury pirinixic acid 2.9418653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 9.8420127859 20464547
MESH:D000230 Adenocarcinoma Doxorubicin 9.8417418594
MESH:D000230 Adenocarcinoma Fluorouracil 9.8417638652
MESH:D000230 Adenocarcinoma Sulindac 9.8411910360
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 15.133712494
MESH:D000236 Adenoma Benzo(a)pyrene 15.136695378
MESH:D000236 Adenoma Methylcholanthrene 15.1310545420 6695378
MESH:D000236 Adenoma Sulindac 15.1310223192
MESH:D018248 Adenoma, Liver Cell Phenobarbital 9.4817620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.4816434500
MESH:D011125 Adenomatous Polyposis Coli Sulindac 4.4311535846 17611924 11874996 16460482 15623613 12394442 19003578
MESH:D000419 Albuminuria Doxorubicin 4.3621441931
MESH:D000740 Anemia Fluorouracil 3.5517963324 16511603 15504547
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.8819183758
MESH:D055963 Asthma, Aspirin-Induced Aspirin 4.5420485159 12372130
MESH:D050197 Atherosclerosis Methylcholanthrene 3.3411922910
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.831440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 2.9719483382
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.5114601052
MESH:D001913 Bowen's Disease Sulindac 5.1611207687
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.1417868700
MESH:D001930 Brain Injuries Progesterone 4.0715665606 15845082 15380490
MESH:D001932 Brain Neoplasms Aspirin 8.5815481559
MESH:D001932 Brain Neoplasms Doxorubicin 8.5817150277
MESH:D001943 Breast Neoplasms marker/mechanism 17922014
MESH:D001943 Breast Neoplasms 2,4-diaminotoluene 4.5811921183
MESH:D001943 Breast Neoplasms Aspirin 4.5815161893
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 4.5817474063 20146248
MESH:D001943 Breast Neoplasms Doxorubicin 4.5815994142 16264153 16115903 15136595 11325840 16096432 16826403 15939500 15634643 18628466 16595493 18695136 18382427 19526202 17983394 15692762 15668708 16322301 17369602 17426702 15567936 15993339 18234424 16935488
MESH:D001943 Breast Neoplasms Fluorouracil 4.5815136595 16595493 19217205 18357371 16110121 16557594 18608205
MESH:D001943 Breast Neoplasms Methylcholanthrene 4.5817474063
MESH:D001943 Breast Neoplasms Progesterone 4.5816175315 15562024 17614352
MESH:D001943 Breast Neoplasms Sulindac 4.5816642371
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.5916097048 15721981 16050911 16227642 16011737 15700767 16192424 15673190 18705752 10355542 3786805 16124888
MESH:D002276 Carcinoid Tumor Doxorubicin 11.7116051944
MESH:D002276 Carcinoid Tumor Fluorouracil 11.7116051944
MESH:D002277 Carcinoma Fluorouracil 8.1217121937
MESH:D002277 Carcinoma Methylcholanthrene 8.1210545420
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 13.6016705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 13.607296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 13.6012907637 21507988 12619106
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 13.6018788625
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 13.6017876044 18059187 16234567 16023760
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 13.6017971768 17045692 17088986 16332177 18930000 16799960
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 13.6020935162 20007298 6705139 17173139 1701930
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 14.677296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 14.671485588 16201981
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 14.6718695887
MESH:D002292 Carcinoma, Renal Cell Vinblastine 14.671485588
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.2420419170
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 7.246189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 7.2416757204 16280240 18986760 17066447
MESH:D009202 Cardiomyopathies Doxorubicin 3.4117131338 17924179 17519947 15792986 15505089 16612575 15476868 17974986 17308081 17007740 16651473 16278810 16269455 15811867 18627295 16242529 17351982 17928571 17329180 16455267 16109756 16952015 16364871 17382496 16731534
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8817334414 16243910
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 19.716135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 19.717505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 19.7120889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 19.7112371664
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 19.7116192471
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.064080065
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 12.579022650 19486331
MESH:D002779 Cholestasis Cyclosporine 12.5719486331
MESH:D002779 Cholestasis pirinixic acid 12.5719176532
MESH:D003110 Colonic Neoplasms Aspirin 8.1112411196
MESH:D003110 Colonic Neoplasms Fluorouracil 8.1117169374 15001691 17016597 16510598 17018589 17725105 18772588 16340194 17172411 17287894
MESH:D003110 Colonic Neoplasms irinotecan 8.1117725105 17287894
MESH:D003110 Colonic Neoplasms Sulindac 8.1112902858 12458338
MESH:D015179 Colorectal Neoplasms Aspirin 8.1617047198
MESH:D015179 Colorectal Neoplasms Doxorubicin 8.1618802399 18259882
MESH:D015179 Colorectal Neoplasms Fluorouracil 8.1616331619 17016601 16282729 17255274 16524972 18949393 18383874 17594712 18802399 17094418 17454858 16391804 17401013 18448328 18509181 14970324 15148649 15289873 16303861 18288408 17695437 20501625
MESH:D015179 Colorectal Neoplasms irinotecan 8.1618259882 17454858 16391804 16303861 17159606 18509181 15273666
MESH:D015179 Colorectal Neoplasms Sulindac 8.1610666051 18059344 11197048 11076880
MESH:D015179 Colorectal Neoplasms Vinblastine 8.1618802399
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.8318551238
MESH:D007644 Darier Disease Fluorouracil 4.6016733453
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.6218759878 14531868 2524372 11906362 8156756 11298694 12868966 8970840
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3418249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.312952479 3621924
MESH:D003929 Diabetic Neuropathies Progesterone 4.3017187935
MESH:D003930 Diabetic Retinopathy Sulindac 4.9912861449 17621415
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 8.5318551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 8.5318289764 1440618 9653073 18648102 8291058 6679447 9022650 11289319 18692083 6482804 16192314 9328219 7440962
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 8.537120509 19085960 6623471 21278145 10092053 9327722 6884620 7179309 11566570 10915739 15998439 15968718 19336974 2869522 3732212 15027814 3786805 4309450 16177239 16227642 17522070 7440962
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 8.5317416283
MESH:D004362 Drug Toxicity Doxorubicin 3.5318602426
MESH:D004421 Dystonia Phenobarbital 3.831851702
MESH:D004487 Edema Aspirin 6.5317259670
MESH:D004487 Edema pirinixic acid 6.5312083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 3.6017692515
MESH:D016889 Endometrial Neoplasms Doxorubicin 3.3317359293
MESH:D004715 Endometriosis Progesterone 8.9116134523
MESH:D004715 Endometriosis Sulindac 8.9115652904
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.9618037988
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.923659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.683922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.7920417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.386401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.067750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.833659116
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 13.303581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 13.3020426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 13.3016530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 13.3016337965 16785472 15173087 17638652 16481741
MESH:D004938 Esophageal Neoplasms Sulindac 13.3012235107
MESH:D005234 Fatty Liver Carbon Tetrachloride 12.0516045604 12631006 19224547 15959796 61145 12795759 17595544 16239168
MESH:D005234 Fatty Liver Cyclosporine 12.0519224547
MESH:D005234 Fatty Liver pirinixic acid 12.0519236843 20131406
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.836705139
MESH:D018221 Fibromatosis, Abdominal Sulindac 5.2914745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 11.1519069698
MESH:D018222 Fibromatosis, Aggressive Sulindac 11.1519069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.7514633661 10962813
MESH:D005355 Fibrosis Carbon Tetrachloride 8.0418705752
MESH:D005355 Fibrosis Cyclosporine 8.0412639820 12168785
MESH:D005764 Gastroesophageal Reflux Sulindac 4.8311910360
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.038708960
MESH:D005909 Glioblastoma Aspirin 7.1812870263
MESH:D005909 Glioblastoma Doxorubicin 7.1817150277
MESH:D005910 Glioma Fluorouracil 2.7916145905
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.867505956
MESH:D006261 Headache Aspirin 4.7715240983
MESH:D006258 Head and Neck Neoplasms Doxorubicin 7.5015692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 7.5015162350 18337622 15102660
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.5620471113
MESH:D006331 Heart Diseases Doxorubicin 3.3518006777 12587719 16495754 16144979 16330681 18674790 17875725 16707910 16879835 16244371 14766674 17888722 16244372
MESH:D006333 Heart Failure Doxorubicin 6.6617481944
MESH:D006333 Heart Failure pirinixic acid 6.6620558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.7315692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2315720958
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.616705139
MESH:D006505 Hepatitis Carbon Tetrachloride 8.6119110552 19900420
MESH:D006529 Hepatomegaly Phenobarbital 7.8516109766
MESH:D006529 Hepatomegaly pirinixic acid 7.8518467677 16221962 19176532 19772884
MESH:D006689 Hodgkin Disease Doxorubicin 7.2718501091 15147373 17606976
MESH:D006689 Hodgkin Disease Vinblastine 7.2718501091 18180244
MESH:D012001 Hyperacusis Aspirin 5.5715240983
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.3416899240
MESH:D006943 Hyperglycemia pirinixic acid 3.0220558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.7515034207
MESH:D006973 Hypertension Cyclosporine 2.0310903974
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9015338365
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.2115869954
MESH:D007249 Inflammation Flavonoids 7.9617296493
MESH:D007249 Inflammation Progesterone 7.9615869954
MESH:D007249 Inflammation Sulindac 7.963291741
MESH:D007333 Insulin Resistance pirinixic acid 2.5116306350
MESH:D007414 Intestinal Neoplasms Sulindac 4.4712584176 12663524 10223192 10213222 12351151 12628509
MESH:D007417 Intestinal Polyps Sulindac 4.8111245490 12394442
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.838074119 9022650
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2515604871
MESH:D007674 Kidney Diseases Cyclosporine 5.758314463 10903974 18776723
MESH:D007674 Kidney Diseases Doxorubicin 5.7515699352 15369732 16775033
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.9816707910
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 16.4816705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 16.486582329
MESH:D007680 Kidney Neoplasms Cyclosporine 16.4812371664
MESH:D007680 Kidney Neoplasms Fluorouracil 16.4816985049
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.9616085563
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.2911903743 11408273 16221502 16943688 17157831 17174718 17334410 21278145 16239168
MESH:D008103 Liver Cirrhosis Phenobarbital 6.2921047994
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 8.129327722 15034207
MESH:D008105 Liver Cirrhosis, Biliary Sulindac 8.1212468960
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 3.3815338365 11481614 12649538 16097048 16248980 16033810 16136751 10355542 15673190 16011737 17805973 18339082 17922224 18472094 16015684 15057751 12445418 18187930 18376398 17721639 14748882 14716833 18251166 17525996 15730626 18395095 18054572 17631135 16638106 15052691 15931870 18705752 12632514 17944888 17761835 18277467 15925388 12632512 18006644 17766677 14620537 18429990 12389079 12609069 17708605 14724832 17869086 18317297 18210741 12741479 17698563 15996030 18472332 18166357 17714472 17976157 15370692 15959796 17481882 18279442 14512876 15876570 17823541 12586293 12666154 18481824 14716496 12667390 15818738 18156304 18412020 16027843 17557913 12445421 18395914 12958196 12546737 15362042 18205269 18420326 13678700 17640975 12898905 16192424 17900296 15123356 16116963 15650968 18263696 17565644 20821823 15893842 18418968
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 3.3816439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.3815474484
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.3715720792 16246199 17285989 15830285 16964402
MESH:D008107 Liver Diseases Phenobarbital 6.3719363144
MESH:D008107 Liver Diseases Sulindac 6.3714986274 16867024
MESH:D017093 Liver Failure Carbon Tetrachloride 3.9715123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.5214706259 16899240
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 20.797678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 20.7918177683 9163691 15890375 2125692
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 20.7921137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 20.7919294768
MESH:D008113 Liver Neoplasms Fluorouracil 20.7918383874 17045692 16603448 15113037
MESH:D008113 Liver Neoplasms Phenobarbital 20.7919812893 8742319 19482888 21047994 19073162 15975961
MESH:D008113 Liver Neoplasms pirinixic acid 20.7920007298 16377806 15890375
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 31.276135515 2876784 2876786
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 31.27598648 3712494 1399818 6587162
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 31.278603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 31.2715583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 31.2716842330 17085340
MESH:D008114 Liver Neoplasms, Experimental kojic acid 31.2718544905
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 31.27598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 31.276150874 1399818 18308698 17172636 2563599
MESH:D008175 Lung Neoplasms Aflatoxin B1 8.2514755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 8.2518569708 20869020 20464547 20064080 18816296 17053015 18520028 20135361 6695378
MESH:D008175 Lung Neoplasms Doxorubicin 8.2517418594 6189445
MESH:D008175 Lung Neoplasms Fluorouracil 8.2515246190
MESH:D008175 Lung Neoplasms Methylcholanthrene 8.2521163286 11893704 6695378 10545420 20512841 15390079 17909032 16337739 9230183 1399818 20970405 16271038 7750092
MESH:D008175 Lung Neoplasms Sulindac 8.2519359593 15713900
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.6015086387
MESH:D008223 Lymphoma Doxorubicin 3.3316098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.6317654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.3815621674
MESH:D008325 Mammary Neoplasms, Experimental 2,4-diaminotoluene 9.4611921183
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 9.4615458769
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 9.4617203775 11408345
MESH:D008545 Melanoma Doxorubicin 5.1916827129
MESH:D008545 Melanoma Sulindac 5.1916642371
MESH:D008545 Melanoma Vinblastine 5.1916248763 15577320 16432458 18332650 15577323 12374674 17761969 18176117 18505091 16809738
MESH:D008654 Mesothelioma Doxorubicin 2.9817638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5916801185
MESH:D008881 Migraine Disorders Aspirin 3.9315240983
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.3215792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.0516381670
MESH:D009062 Mouth Neoplasms Fluorouracil 8.0516757204 18986760
MESH:D052016 Mucositis Doxorubicin 11.7817415656
MESH:D052016 Mucositis irinotecan 11.7817159606
MESH:D009135 Muscular Diseases pirinixic acid 3.3216239165
MESH:D009203 Myocardial Infarction Aspirin 9.1212692751
MESH:D009203 Myocardial Infarction Doxorubicin 9.1215857846 19429709
MESH:D009203 Myocardial Infarction pirinixic acid 9.1219151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8016411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.2817484760
MESH:D009325 Nausea Aspirin 5.0215240983
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.677678174 18551238
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 9.153581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 9.1518259882
MESH:D009362 Neoplasm Metastasis irinotecan 9.1518259882
MESH:D009369 Neoplasms Benzo(a)pyrene 7.6711141357
MESH:D009369 Neoplasms Fluorouracil 7.6718239605 18600527 16928823
MESH:D009369 Neoplasms pirinixic acid 7.6717405874
MESH:D009401 Nephrosis Doxorubicin 4.5816636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.7618481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.7616889571 15640375
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 2.796679447
MESH:D009447 Neuroblastoma Doxorubicin 6.8315555623
MESH:D009447 Neuroblastoma irinotecan 6.838761367
MESH:D019636 Neurodegenerative Diseases Sulindac 4.1116850258 17266991
MESH:D017599 Neuroectodermal Tumors irinotecan 4.548761367
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.3116436463
MESH:D009503 Neutropenia Vinblastine 4.3917378895
MESH:D009765 Obesity pirinixic acid 1.7720558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.3316049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 8.334026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.833988306
MESH:D010003 Osteoarthritis Aspirin 3.947009135
MESH:D010018 Osteomalacia Phenobarbital 4.1717016548
MESH:D012516 Osteosarcoma Doxorubicin 3.9615930896
MESH:D010051 Ovarian Neoplasms Progesterone 2.4716525653 17393432
MESH:D010146 Pain Aspirin 6.946363464 6995502
MESH:D010146 Pain Sulindac 6.943291741
MESH:D010190 Pancreatic Neoplasms Fluorouracil 8.3619003803 16929163 16500647 15113037
MESH:D010190 Pancreatic Neoplasms Phenobarbital 8.3616965848
MESH:D010190 Pancreatic Neoplasms Sulindac 8.3611504793 16820089
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.307296757
MESH:D010438 Peptic Ulcer Hemorrhage Aspirin 5.3511156591
MESH:D020795 Photophobia Aspirin 5.5715240983
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.286228378
MESH:D003557 Phyllodes Tumor Doxorubicin 4.9617983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.9617638057
MESH:D011230 Precancerous Conditions Cyclosporine 8.4312371664
MESH:D011230 Precancerous Conditions Phenobarbital 8.432563599
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.2117292933
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.2115749863 16729912 16868541 18437689 16888761 15897917
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.2118626508 19082440
MESH:D011471 Prostatic Neoplasms Hyaluronic Acid 2.2116864594
MESH:D019310 Pseudolymphoma Phenobarbital 4.3012752131
MESH:D011565 Psoriasis Cyclosporine 2.1616882103
MESH:D012004 Rectal Neoplasms Fluorouracil 3.8518722050 15538739 18286688 16160472
MESH:D051437 Renal Insufficiency Doxorubicin 4.0317922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.2919058328
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.233692021
MESH:D012220 Rhinitis Aspirin 4.2112372130
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7918045962
MESH:D012509 Sarcoma Doxorubicin 3.8215625365 17710206 16767912 17203757 15675481 18313854
MESH:D012512 Sarcoma, Ewing's Doxorubicin 4.0614601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.6017846226
MESH:D012640 Seizures 2,6-dinitrotoluene 5.5018551238
MESH:D012640 Seizures Phenobarbital 5.503137016 4039156 11442880 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.636407741
MESH:D012851 Sinus Thrombosis, Intracranial Aspirin 5.0712269725
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.5110029692 19755658
MESH:D012878 Skin Neoplasms Doxorubicin 5.5115692506
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.3817203757 15625365 16767912
MESH:D013119 Spinal Cord Injuries Progesterone 4.0915862959 16503802
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.332093021 20155912
MESH:D013274 Stomach Neoplasms Fluorouracil 3.3316424979 16951190 18396642 15786421 17522103 17498489 18567086 17172411 19084572 19015929
MESH:D013274 Stomach Neoplasms irinotecan 3.3315723263
MESH:D020521 Stroke Aspirin 4.2316403987
MESH:D013927 Thrombosis Aspirin 4.3517672075
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 11.171399818 6582329 6587162 7505956 3712494
MESH:D013964 Thyroid Neoplasms Doxorubicin 11.1717909728 16010429
MESH:D013964 Thyroid Neoplasms Phenobarbital 11.171399818
MESH:D014062 Tongue Neoplasms Fluorouracil 3.8216280240
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 11.3116049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 11.318074119
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 11.3117053015
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 11.3117653716
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.1310091137
MESH:D014581 Urticaria Aspirin 4.2610982225 20485159
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.7116803524
MESH:D014594 Uterine Neoplasms Sulindac 4.4218645019
MESH:D014605 Uveitis Cyclosporine 3.791336536
MESH:D014625 Vaginal Neoplasms Vinblastine 4.8615577323
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.0316364871 17638931 17678736 17334414
MESH:D014985 Xerophthalmia Cyclosporine 4.2517120751
Pathway ID Pathway Name
KEGG:04512 ECM-receptor interaction
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA29340
    • No data
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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